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01-02-2021 | Glioblastoma | Original Article

Thalamic tumors in children: case series from our institution and literature review

Authors: Daniela Renedo, Florencia Ferraro, Agustín Ruiz Johnson, Romina Argañaraz, Sebastian Giovannini, Joaquín Pérez Zabala, Elena Zemma, Beatriz Mantese

Published in: Child's Nervous System | Issue 2/2021

Abstract

Purpose

To describe a case series of children with thalamic tumors treated at our institution in a 5-year period.

Method

A retrospective and observational study was performed. The records of 15 patients between 2013 and 2018 were analyzed.

Results

From 2013 to 2018, 15 patients were treated at our institution. The male to female index was 1.5, and the median age was 8.9 (IQR 4.75–13). Seven (46%) tumors were left-sided, seven (46%) were right-sided, and one (6%) was bilateral. All patients were symptomatic at the time of treatment. Motor deficit was the most common form of presentation (73%). Gross-total resection was performed in two (13.3%) patients, subtotal resection was performed in two other patients (13.3%), and for the rest of the patients (73.3%), the chosen surgical approach was a stereotactic-guided biopsy. The average of procedures was 3.4, mostly related to the treatment for hydrocephalus. Twelve patients (80%) received treatment for hydrocephalus. Nine patients (75%) were treated with ventriculoperitoneal shunts, and four patients (33%) underwent endoscopic third ventriculostomy. High-grade tumors predominated. Grade IV tumors were diagnosed in six patients (40%), followed by grade III in four patients (26.6%), grade II in three (20%) patients, and grade I in two (13.3%) patients. Chemotherapy was given in 93% of the cases, being temozolomide, the most used drug.

Conclusion

The clinical and surgical approaches for thalamic tumors in children have changed over time. At our institution, the lesser invasive surgical procedures are now being used more frequently.

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Title: Thalamic tumors in children: case series from our institution and literature review
Authors: Daniela Renedo
Florencia Ferraro
Agustín Ruiz Johnson
Romina Argañaraz
Sebastian Giovannini
Joaquín Pérez Zabala
Elena Zemma
Beatriz Mantese
Publication date: 01-02-2021
Publisher: Springer Berlin Heidelberg
Keywords: Glioblastoma
Astrocytoma
Glioma
Hydrocephalus
Hydrocephalus
Glioma
Astrocytoma
Glioblastoma
Hydrocephalus
Astrocytoma
Glioblastoma
Glioma
Published in: Child's Nervous System / Issue 2/2021
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-020-04830-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Thalamic tumors in children: case series from our institution and literature review

Abstract

Purpose

Method

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Method

Results

Conclusion

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