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Heart and Vessels
Published in: Heart and Vessels 10/2022

30-04-2022 | Intravascular Ultrasound | Original Article

Influence of myocardial bridge on atherosclerotic plaque distribution and characteristics evaluated by near-infrared spectroscopy intravascular ultrasound

Authors: Kan Saito, Hideki Kitahara, Takaaki Mastuoka, ·Naoto Mori, Kazuya Tateishi, Yoshihide Fujimoto, Yoshio Kobayashi

Published in: Heart and Vessels | Issue 10/2022

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Abstract

Background

This study aims to clarify whether myocardial bridge (MB) could influence atherosclerotic plaque characteristics assessed using near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) imaging.

Methods

One hundred and sixteen patients who underwent percutaneous coronary intervention (PCI) using NIRS-IVUS imaging were included. MB was defined as an echo-lucent band surrounding left anterior descending artery (LAD). In MB patients, LAD was divided into three segments: proximal, MB, and distal segments. In non-MB patients, corresponding three segments were defined based on the average length of the above segments. Segmental maximum plaque burden and lipid content derived from NIRS-IVUS imaging in the section of maximum plaque burden were evaluated in each segment. Lipid content of atherosclerotic plaque was evaluated as lipid core burden index (LCBI) and maxLCBI4mm. LCBI is the fraction of pixels indicating lipid within a region multiplied by 1000, and the maximum LCBI in any 4-mm region was defined as maxLCBI4mm.

Results

MB was identified in 42 patients. MB was not associated with maximum plaque burden in proximal segment. LCBI and maxLCBI4mm were significantly lower in patients with MB than those without in proximal segment. Multivariable analysis demonstrated both MB and maximum plaque burden in proximal segment to be independent predictors of LCBI in proximal segment.

Conclusions

Lipid content of atherosclerotic plaque assessed by NIRS-IVUS imaging was significantly smaller in patients with MB than those without. MB could be considered as a predictor of lipid content of atherosclerotic plaque when assessed by NIRS-IVUS imaging.
Appendix
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Metadata
Title
Influence of myocardial bridge on atherosclerotic plaque distribution and characteristics evaluated by near-infrared spectroscopy intravascular ultrasound
Authors
Kan Saito
Hideki Kitahara
Takaaki Mastuoka
·Naoto Mori
Kazuya Tateishi
Yoshihide Fujimoto
Yoshio Kobayashi
Publication date
30-04-2022
Publisher
Springer Japan
Published in
Heart and Vessels / Issue 10/2022
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-022-02083-2

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