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Published in: Heart and Vessels 10/2022

05-05-2022 | Heart Failure | Original Article

Relationship between physical function at discharge and hospital meal intake in elderly patients with heart failure

Authors: Ikko Kubo, Kazuhiro P. Izawa, Nozomu Kajisa, Asami Ogura, Masashi Kanai, Ryo Nishio, Daisuke Matsumoto

Published in: Heart and Vessels | Issue 10/2022

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Abstract

The relationship between low physical function (LPF) at discharge and food intake percentage (FIP) during hospitalization is unclear. We aimed to clarify the relationship between LPF at discharge and FIP and the change in nutritional status during hospitalization in elderly patients with heart failure (HF), and determine cutoff values for FIP and change in nutritional status during hospitalization. We included 431 consecutive patients aged ≥ 65 years who were hospitalized for HF and underwent cardiac rehabilitation (CR) from 2017 to 2019. Physical function at discharge was classified into two groups according to the Short Performance Physical Battery (SPPB): low physical function (LPF) (SPPB ≤ 9) and high physical function (HPF) (SPPB > 9). We compared background, clinical parameters, pre-hospital walking level, CR progress, nutritional factors during hospitalization including FIP of the main dish and side dish, and changes in nutritional status using the Geriatric Nutritional Risk Index (ΔGNRI) at admission and discharge. Multiple logistic regression analysis was also performed. The final analysis included 213 patients (age, 81.6 years) divided into the LPF (n = 136) and HPF groups (n = 77). The LPF group showed low FIP and a high ΔGNRI value. Multivariate analysis showed FIP main dish, ΔGNRI, worsening renal function, pre-hospital walking level, and days to start of walking to be factors influencing LPF at discharge. Respective cutoff values for FIP main dish and ΔGNRI predicting LPF at discharge were 82.2% and 4.24. FIP main dish during hospitalization and ΔGNRI were associated with LPF at discharge.
Literature
1.
go back to reference Okura Y, Ramadan MM, Ohno Y, Mitsuma W, Tanaka K, Ito M, Suzuki K, Tanabe N, Kodama M, Aizawa Y (2008) Impending epidemic: future projection of heart failure in Japan to the year 2055. Circ J 72:489–491CrossRef Okura Y, Ramadan MM, Ohno Y, Mitsuma W, Tanaka K, Ito M, Suzuki K, Tanabe N, Kodama M, Aizawa Y (2008) Impending epidemic: future projection of heart failure in Japan to the year 2055. Circ J 72:489–491CrossRef
2.
go back to reference Tanaka S, Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Maekawa E, Noda C, Yamaoka-T M, Matsunaga A, Masuda T, Ako J (2018) Incremental value of objective frailty assessment to predict mortality in elderly patients hospitalized for heart failure. J Card Fail 24(11):723–732CrossRef Tanaka S, Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Maekawa E, Noda C, Yamaoka-T M, Matsunaga A, Masuda T, Ako J (2018) Incremental value of objective frailty assessment to predict mortality in elderly patients hospitalized for heart failure. J Card Fail 24(11):723–732CrossRef
3.
go back to reference Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Tanaka S, Ichinosawa Y, Maekawa R, Noda C, Yamamoto-T M, Matsunaga A, Ako J (2017) Sarcopenia prevalence and prognostic implications in elderly patients with cardiovascular disease. JCSM Clin Rep 2(2):1–13CrossRef Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Tanaka S, Ichinosawa Y, Maekawa R, Noda C, Yamamoto-T M, Matsunaga A, Ako J (2017) Sarcopenia prevalence and prognostic implications in elderly patients with cardiovascular disease. JCSM Clin Rep 2(2):1–13CrossRef
4.
go back to reference Murad K, Kitzman DW (2012) Frailty and multiple comorbidities in the elderly patient with heart failure: implications for management. Heart Fail Rev 17:581–588CrossRef Murad K, Kitzman DW (2012) Frailty and multiple comorbidities in the elderly patient with heart failure: implications for management. Heart Fail Rev 17:581–588CrossRef
5.
go back to reference Saltin B, Blomqvist G, Hitchell JH, Johnson RL Jr, Wildenthal K, Chapman CB (1968) Response to exercise after bed rest and after training. Circulation 38(5 Suppl):VII1–VII78PubMed Saltin B, Blomqvist G, Hitchell JH, Johnson RL Jr, Wildenthal K, Chapman CB (1968) Response to exercise after bed rest and after training. Circulation 38(5 Suppl):VII1–VII78PubMed
6.
go back to reference Gill TM, Allore HG, Gahbauer EA, Murphy TE (2010) Change in disability after hospitalization or restricted activity in older persons. JAMA 304:1919–1928CrossRef Gill TM, Allore HG, Gahbauer EA, Murphy TE (2010) Change in disability after hospitalization or restricted activity in older persons. JAMA 304:1919–1928CrossRef
8.
go back to reference Giezenaar C, Chapman I, Luscombe-Marsh N, Feinle-Bisset C, Horowitz M, Soenen S (2016) Ageing is associated with decreases in appetite and energy intake–a meta-analysis in healthy adults. Nutrients 8:28CrossRef Giezenaar C, Chapman I, Luscombe-Marsh N, Feinle-Bisset C, Horowitz M, Soenen S (2016) Ageing is associated with decreases in appetite and energy intake–a meta-analysis in healthy adults. Nutrients 8:28CrossRef
9.
go back to reference Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, Jang HC, Kang K, Kim M, Kim S, Kojima T, Kuzuya M, Lee SY, Lee WJ, Lee Y, Liang CK, Lim JY, Peng LN, Sugimoto K, Tanaka T, Won CW, Yamada M, Zhang T, Akishita M, Arai H (2020) Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc 21:300-307.e2CrossRef Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, Jang HC, Kang K, Kim M, Kim S, Kojima T, Kuzuya M, Lee SY, Lee WJ, Lee Y, Liang CK, Lim JY, Peng LN, Sugimoto K, Tanaka T, Won CW, Yamada M, Zhang T, Akishita M, Arai H (2020) Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc 21:300-307.e2CrossRef
10.
go back to reference Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB (1995) Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 332:556–561CrossRef Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB (1995) Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 332:556–561CrossRef
11.
go back to reference Puthoff ML (2008) Outcome measures in cardiopulmonary physical therapy: short physical performance battery. Cardiopulm Phys Ther J 19:17–22CrossRef Puthoff ML (2008) Outcome measures in cardiopulmonary physical therapy: short physical performance battery. Cardiopulm Phys Ther J 19:17–22CrossRef
12.
go back to reference Saitoh M, Itoh H, Moritomi N, Ozawa T, Ishii N, Uewaki R, Hori K, Shiotani Y, Ando M, Nakashima S, Kawai K, Ohno A, Nagayama M (2014) Impact of chronic kidney disease and anemia on physical function in patients with chronic heart failure. Cardiorenal Med 4(2):73–81CrossRef Saitoh M, Itoh H, Moritomi N, Ozawa T, Ishii N, Uewaki R, Hori K, Shiotani Y, Ando M, Nakashima S, Kawai K, Ohno A, Nagayama M (2014) Impact of chronic kidney disease and anemia on physical function in patients with chronic heart failure. Cardiorenal Med 4(2):73–81CrossRef
13.
go back to reference Izawa KP, Watanabe S, Oka K (2015) Relationship of thresholds of physical performance to nutritional status in older hospitalized male cardiac patients. Geriatr Gerontol Int 15(2):189–195CrossRef Izawa KP, Watanabe S, Oka K (2015) Relationship of thresholds of physical performance to nutritional status in older hospitalized male cardiac patients. Geriatr Gerontol Int 15(2):189–195CrossRef
14.
go back to reference Matsuo H, Yoshimura Y, Fujita S, Maeno Y (2019) Risk of malnutrition is associated with poor physical function in patients undergoing cardiac rehabilitation following heart failure. Nutr Diet 76:82–88CrossRef Matsuo H, Yoshimura Y, Fujita S, Maeno Y (2019) Risk of malnutrition is associated with poor physical function in patients undergoing cardiac rehabilitation following heart failure. Nutr Diet 76:82–88CrossRef
15.
go back to reference Kubo I, Izawa KP, Kajisa N, Ryu M, Hideki Akasaka H, Ogura A, Kanai M, Matsuzoe H, Matsumoto D (2020) Worsening renal function during hospitalization in elderly patients with heart failure: an independent factor of activities of daily living decline. Heart Vessels 36:76–84CrossRef Kubo I, Izawa KP, Kajisa N, Ryu M, Hideki Akasaka H, Ogura A, Kanai M, Matsuzoe H, Matsumoto D (2020) Worsening renal function during hospitalization in elderly patients with heart failure: an independent factor of activities of daily living decline. Heart Vessels 36:76–84CrossRef
16.
go back to reference Yoshida T, Shoji S, Shiraishi Y, Kawana M, Kohno T, Inoue K, Fukuda K, Hidenreich PA, Kohsaka S (2020) Hospital meal intake in acute heart failure patients and its association with long-term outcomes. Open Heart 7:e001248CrossRef Yoshida T, Shoji S, Shiraishi Y, Kawana M, Kohno T, Inoue K, Fukuda K, Hidenreich PA, Kohsaka S (2020) Hospital meal intake in acute heart failure patients and its association with long-term outcomes. Open Heart 7:e001248CrossRef
17.
go back to reference Iida S, Aoki C (2017) Reliability of 10-meter walking test [part 1]: Influence of different measurement orders on the fast walking and normal walking. Rigakuryoho Gaku 32:81–84CrossRef Iida S, Aoki C (2017) Reliability of 10-meter walking test [part 1]: Influence of different measurement orders on the fast walking and normal walking. Rigakuryoho Gaku 32:81–84CrossRef
18.
go back to reference Kinugasa Y, Kato M, Sugihara S, Hirai M, Yamada K, Yanagihara K, Yamamoto K (2013) Geriatric nutritional risk index predicts functional dependency and mortality in patients with heart failure with preserved ejection fraction. Circ J 77:705-711CrossRef Kinugasa Y, Kato M, Sugihara S, Hirai M, Yamada K, Yanagihara K, Yamamoto K (2013) Geriatric nutritional risk index predicts functional dependency and mortality in patients with heart failure with preserved ejection fraction. Circ J 77:705-711CrossRef
19.
go back to reference Honda Y, Nagai T, Iwakami N, Sugano Y, Honda S, Okada A, Asaumi Y, Aiba T, Noguchi T, Kusano K, Ogawa H, Yasuda S, Anzai T (2016) Usefulness of Geriatric Nutritional Risk Index for assessing nutritional status and its prognostic impact in patients aged ≥65 years with acute heart failure. Am J Cardiol 118:550–555CrossRef Honda Y, Nagai T, Iwakami N, Sugano Y, Honda S, Okada A, Asaumi Y, Aiba T, Noguchi T, Kusano K, Ogawa H, Yasuda S, Anzai T (2016) Usefulness of Geriatric Nutritional Risk Index for assessing nutritional status and its prognostic impact in patients aged ≥65 years with acute heart failure. Am J Cardiol 118:550–555CrossRef
20.
go back to reference Yajima T, Yajima K, Takahashi H (2020) Impact of annual change in geriatric nutritional risk index on mortality in patients undergoing hemodialysis. Nutrients 12:3333CrossRef Yajima T, Yajima K, Takahashi H (2020) Impact of annual change in geriatric nutritional risk index on mortality in patients undergoing hemodialysis. Nutrients 12:3333CrossRef
21.
go back to reference Mudge AM, Ross LJ, Young AM, Isenring EA, Banks MD (2011) Helping understand nutritional gaps in the elderly (HUNGER): a prospective study of patient factors associated with inadequate nutritional intake in older medical inpatients. Clin Nutr 30:320–325CrossRef Mudge AM, Ross LJ, Young AM, Isenring EA, Banks MD (2011) Helping understand nutritional gaps in the elderly (HUNGER): a prospective study of patient factors associated with inadequate nutritional intake in older medical inpatients. Clin Nutr 30:320–325CrossRef
22.
go back to reference Ogawa M, Izawa KP, Satomi-Kobayashi S, Tuboi Y, Komaki K, Gotake Y, Yoshida N, Wakita J, Uchida J, Sakai Y, Okita Y (2019) Effects of postoperative dietary intake on functional recovery of patients undergoing cardiac surgery. Nutr Metab Cardiovasc Dis 29:90–96CrossRef Ogawa M, Izawa KP, Satomi-Kobayashi S, Tuboi Y, Komaki K, Gotake Y, Yoshida N, Wakita J, Uchida J, Sakai Y, Okita Y (2019) Effects of postoperative dietary intake on functional recovery of patients undergoing cardiac surgery. Nutr Metab Cardiovasc Dis 29:90–96CrossRef
23.
go back to reference Ishihara K, Izawa KP, Kitamura M, Ogawa M, Shimogai T, Kanejima Y, Morisawa T, Shimizu I (2020) Relation of poor nutritional status to mild cognitive impairment in patients with coronary artery disease. J Nutr Health Aging 24:1080–1086CrossRef Ishihara K, Izawa KP, Kitamura M, Ogawa M, Shimogai T, Kanejima Y, Morisawa T, Shimizu I (2020) Relation of poor nutritional status to mild cognitive impairment in patients with coronary artery disease. J Nutr Health Aging 24:1080–1086CrossRef
24.
go back to reference Harris JA, Benedict FG (1918) A biometric study of human basal metabolism. Proc Natl Acad Sci USA 4:370–373CrossRef Harris JA, Benedict FG (1918) A biometric study of human basal metabolism. Proc Natl Acad Sci USA 4:370–373CrossRef
25.
go back to reference Tanaka S, Ohkawara K, Ishikawa TK, Morita A, Watanabe S (2008) Accuracy of predictive equations for basal metabolic rate and contribution of abdominal fat distribution to basal metabolic rate in obese Japanese people. Anti-Aging Med 5:17–21CrossRef Tanaka S, Ohkawara K, Ishikawa TK, Morita A, Watanabe S (2008) Accuracy of predictive equations for basal metabolic rate and contribution of abdominal fat distribution to basal metabolic rate in obese Japanese people. Anti-Aging Med 5:17–21CrossRef
26.
go back to reference Okabe T, Yakushiji T, Kido T, Oyama Y, Igawa W, Ono M, Ebara S, Yamashita K, Yamamoto MH, Saito S, Amemiya K, Isomura N, Araki H, Ochiai M (2017) Relationship between worsening renal function and long-term cardiovascular mortality in heart failure patients. Int J Cardiol 230:47–52CrossRef Okabe T, Yakushiji T, Kido T, Oyama Y, Igawa W, Ono M, Ebara S, Yamashita K, Yamamoto MH, Saito S, Amemiya K, Isomura N, Araki H, Ochiai M (2017) Relationship between worsening renal function and long-term cardiovascular mortality in heart failure patients. Int J Cardiol 230:47–52CrossRef
27.
go back to reference Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A (2009) Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 53:982–992CrossRef Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A (2009) Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 53:982–992CrossRef
28.
go back to reference JCS Joint Working Group (2013) Guidelines for treatment of acute heart failure (JCS 2011). Circ J 77:2157–2201CrossRef JCS Joint Working Group (2013) Guidelines for treatment of acute heart failure (JCS 2011). Circ J 77:2157–2201CrossRef
29.
go back to reference Ottenbacher KJ, Hsu Y, Granger CV, Fiedler RC (1996) The reliability of the functional independence measure: a quantitative review. Arch Phys Med Rehabil 77:1226–1232CrossRef Ottenbacher KJ, Hsu Y, Granger CV, Fiedler RC (1996) The reliability of the functional independence measure: a quantitative review. Arch Phys Med Rehabil 77:1226–1232CrossRef
30.
go back to reference Akobeng AK (2007) Understanding diagnostic tests 3: receiver operating characteristic curves. Acta Paediatr 96:644–647CrossRef Akobeng AK (2007) Understanding diagnostic tests 3: receiver operating characteristic curves. Acta Paediatr 96:644–647CrossRef
31.
go back to reference Yokoyama Y, Kitamura A, Seino S, Kim H, Obuchi S, Kawai H, Hirano H, Watanabe Y, Motokawa K, Narita M, Shinkai S (2021) Association of nutrient-derived dietary pattern with sarcopenia and its components in community-dwelling older Japanese: a cross-sectional study. Nutr J 20:7CrossRef Yokoyama Y, Kitamura A, Seino S, Kim H, Obuchi S, Kawai H, Hirano H, Watanabe Y, Motokawa K, Narita M, Shinkai S (2021) Association of nutrient-derived dietary pattern with sarcopenia and its components in community-dwelling older Japanese: a cross-sectional study. Nutr J 20:7CrossRef
32.
go back to reference Landi F, Liperoti R, Russo A, Giovannini S, Tosato M, Barillaro C, Capoluongo E, Bernabei R, Onder G (2013) Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study. Eur J Nutr 52:1261–1268CrossRef Landi F, Liperoti R, Russo A, Giovannini S, Tosato M, Barillaro C, Capoluongo E, Bernabei R, Onder G (2013) Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study. Eur J Nutr 52:1261–1268CrossRef
33.
go back to reference Valente MA, Voors AA, Damman K, Van Veldhuisen DJ, Massie BM, O’Connor CM, Metra M, Ponikowski P, Teerlink J, Cotter G, Davison B, Cleland JGF, Givertz MM, Bloomfield DM, Fiuzat M, Dittrich HC, Hillege HL (2014) Diuretic response in acute heart failure: clinical characteristic and prognostic significance. Eur Heart J 35:1284–1293CrossRef Valente MA, Voors AA, Damman K, Van Veldhuisen DJ, Massie BM, O’Connor CM, Metra M, Ponikowski P, Teerlink J, Cotter G, Davison B, Cleland JGF, Givertz MM, Bloomfield DM, Fiuzat M, Dittrich HC, Hillege HL (2014) Diuretic response in acute heart failure: clinical characteristic and prognostic significance. Eur Heart J 35:1284–1293CrossRef
34.
go back to reference Voors AA, Davison BA, Teerlink JR, Felker GM, Cotter G, Filippatos G, Greenberg BH, Pang PS, Levin B, Hua TA, Severin T, Ponikowski P, Metra M (2014) Diuretic response in patients with acute decompensated heart failure: characteristics and clinical outcome–an analysis from RELAX-AHF. Eur J Heart Fail 16:1230–1240CrossRef Voors AA, Davison BA, Teerlink JR, Felker GM, Cotter G, Filippatos G, Greenberg BH, Pang PS, Levin B, Hua TA, Severin T, Ponikowski P, Metra M (2014) Diuretic response in patients with acute decompensated heart failure: characteristics and clinical outcome–an analysis from RELAX-AHF. Eur J Heart Fail 16:1230–1240CrossRef
35.
go back to reference Cowie MR, Komajda M, Murray-Thomas T, Underwood J, Ticho B (2006) Prevalence and impact of worsening renal function in patients hospitalized with decompensated heart failure: results of the prospective outcomes study in heart failure (POSH). Eur Heart J 27:1216–1222CrossRef Cowie MR, Komajda M, Murray-Thomas T, Underwood J, Ticho B (2006) Prevalence and impact of worsening renal function in patients hospitalized with decompensated heart failure: results of the prospective outcomes study in heart failure (POSH). Eur Heart J 27:1216–1222CrossRef
36.
go back to reference Martone AM, Bianchi L, Abete P, Bellelly G, Bo M, Cherubini A, Corica F, Bari MD, Maggio M, Manca GM, Marzetti E, Rizzo MR, Rossi A, Volpato S, Landi F (2017) The incidence of sarcopenia among hospitalized older patients: results from the Glisten study. J Cachexia Sarcopenia Muscle 8:907–914CrossRef Martone AM, Bianchi L, Abete P, Bellelly G, Bo M, Cherubini A, Corica F, Bari MD, Maggio M, Manca GM, Marzetti E, Rizzo MR, Rossi A, Volpato S, Landi F (2017) The incidence of sarcopenia among hospitalized older patients: results from the Glisten study. J Cachexia Sarcopenia Muscle 8:907–914CrossRef
37.
go back to reference Carrero JJ, Aguilera A, Stenvinkel P, Gil F, Selgas R, Lindholm B (2008) Appetite disorders in uremia. J Ren Nutr 18(1):107–113CrossRef Carrero JJ, Aguilera A, Stenvinkel P, Gil F, Selgas R, Lindholm B (2008) Appetite disorders in uremia. J Ren Nutr 18(1):107–113CrossRef
38.
go back to reference Landi F, Calvani R, Tosato M, Marton AM, Ortolani E, Savera G, Sisto A, Marzetti E (2016) Anorexia of aging: Risk factors, consequences, and potential treatments. Nutrients 8:69CrossRef Landi F, Calvani R, Tosato M, Marton AM, Ortolani E, Savera G, Sisto A, Marzetti E (2016) Anorexia of aging: Risk factors, consequences, and potential treatments. Nutrients 8:69CrossRef
Metadata
Title
Relationship between physical function at discharge and hospital meal intake in elderly patients with heart failure
Authors
Ikko Kubo
Kazuhiro P. Izawa
Nozomu Kajisa
Asami Ogura
Masashi Kanai
Ryo Nishio
Daisuke Matsumoto
Publication date
05-05-2022
Publisher
Springer Japan
Keyword
Heart Failure
Published in
Heart and Vessels / Issue 10/2022
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-022-02077-0

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