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Published in: Heart and Vessels 12/2020

01-12-2020 | Antiarrhythmic Drugs | Original Article

Cryoballoon versus radiofrequency ablation for paroxysmal atrial fibrillation in hemodialysis patients

Authors: Tomomasa Takamiya, Junichi Nitta, Osamu Inaba, Akira Sato, Yukihiro Inamura, Nobutaka Kato, Kazuya Murata, Takashi Ikenouchi, Toshikazu Kono, Giichi Nitta, Yutaka Matsumura, Yoshihide Takahashi, Masahiko Goya, Tetsuo Sasano

Published in: Heart and Vessels | Issue 12/2020

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Abstract

Introduction

Little evidence exists regarding cryoballoon ablation (CBA) of paroxysmal atrial fibrillation (PAF) in hemodialysis (HD) patients. We compared CBA and radiofrequency ablation (RFA) of PAF in HD patients, referring to CBA of PAF in non-HD patients.

Methods and results

This historical cohort study examined 88 patients who underwent catheter ablation of PAF, including 21 HD patients with a second-generation 28-mm cryoballoon (CB-HD group), 17 HD patients with a non-force-sensing radiofrequency catheter (RF-HD group), and 50 non-HD patients with a cryoballoon (CB-non-HD group). Pulmonary vein (PV) isolation alone aside from cavotricuspid isthmus ablation was performed in 14 (67%) in the CB-HD group, 12 (71%) in the RF-HD group, and 36 (72%) in the CB-non-HD group (P = 0.95), without isoproterenol-induced non-PV triggers. Non-PV trigger ablation was added to the other patients. The Kaplan–Meier estimated 1-year freedom from atrial tachyarrhythmia recurrence without antiarrhythmic drugs after a single procedure was 76%, 59%, and, 92% in the CB-HD, RF-HD, and CB-non-HD groups, respectively (P = 0.002). The mean procedure time was shorter in the CB-HD group than in the RF-HD group (127 vs. 199 min; P < 0.001). In the second procedure, the median number of reconnected pulmonary veins was 0.5 in the CB-HD group versus 2.0 in the RF-HD group (P = 0.17).

Conclusion

For PAF in HD patients, CBA showed a comparable single-procedure efficacy to that of RFA with a short procedure time. CBA may be a reasonable initial procedure for HD patients suffering from symptomatic PAF.
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Metadata
Title
Cryoballoon versus radiofrequency ablation for paroxysmal atrial fibrillation in hemodialysis patients
Authors
Tomomasa Takamiya
Junichi Nitta
Osamu Inaba
Akira Sato
Yukihiro Inamura
Nobutaka Kato
Kazuya Murata
Takashi Ikenouchi
Toshikazu Kono
Giichi Nitta
Yutaka Matsumura
Yoshihide Takahashi
Masahiko Goya
Tetsuo Sasano
Publication date
01-12-2020
Publisher
Springer Japan
Published in
Heart and Vessels / Issue 12/2020
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-020-01646-5

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