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Antiarrhythmic Drugs 

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  1. Open Access 18-04-2024 | Atrial Fibrillation | Online First

    Three-year incidence of pacemaker implantation in patients with atrial fibrillation and sinus node dysfunction receiving ablation versus antiarrhythmic drugs

    Atrial fibrillation (AF) is the most common cardiac arrhythmia among adults affecting up to 6 million people in the US and is expected to rise to 7.2 million by 2035 [ 1 , 2 ]. Sinus node dysfunction (SND) is characterized by abnormalities in the …

  2. Open Access 20-01-2024 | Antiarrhythmic Drugs | OriginalPaper

    An Economic Evaluation of a Streamlined Day-Case Atrial Fibrillation Ablation Protocol and Conventional Cryoballoon Ablation versus Antiarrhythmic Drugs in a UK Paroxysmal Atrial Fibrillation Population

    Ablation is a recognised treatment option for individuals with atrial fibrillation (AF) who remain symptomatic despite optimised antiarrhythmic drug (AAD) therapy, and while ablation can be performed on a day-case basis, it usually involves an …

  3. Open Access 19-02-2024 | Implantable Cardioverter Defibrillator | Online First

    Use of class IC antiarrhythmic drugs in patients with structural heart disease and implantable cardioverter defibrillator

    The presence of structural heart disease (SHD) and reduced ejection fraction predispose to ventricular arrhythmias (VA), affecting morbidity and mortality in a relevant subgroup of patients [ 1 ]. Pharmacological treatment options are limited as …

  4. 01-01-2022 | Antiarrhythmic Drugs | News

    Antiarrhythmic drugs

    Lack of efficacy: case report
  5. 01-03-2022 | Antiarrhythmic Drugs | News

    Antiarrhythmic drugs

    Various toxicities: 5 case reports
  6. 01-05-2022 | Antiarrhythmic Drugs | Report

    Catheter Ablation vs. Antiarrhythmic Drugs as Therapy for Paroxysmal Atrial Fibrillation

    For patients with paroxysmal atrial fibrillation (PAF), catheter ablation was a superior therapy compared to antiarrhythmic drugs in reducing both atrial fibrillation and hospitalizations without an increase in adverse events.

  7. 06-07-2022 | Antiarrhythmic Drugs | EditorialNotes

    Do class IC antiarrhythmics drugs need to be cast aside in atrial fibrillation patients with minimal coronary artery disease?

  8. 01-07-2021 | Antiarrhythmic Drugs | OriginalPaper

    Safety and Effectiveness of Rivaroxaban in Combination with Various Antiarrhythmic Drugs in Patients with Non-Permanent Atrial Fibrillation

    Atrial fibrillation (AF) is associated with an increased risk of ischemic stroke. Some patients with AF receive rhythm control therapy using various antiarrhythmic drugs (AADs), such as amiodarone, dronedarone, or propafenone, to maintain sinus …

  9. 01-05-2021 | Antiarrhythmic Drugs | ReviewPaper

    Long-Term Outcomes and Improvements in Quality of Life in Patients with Atrial Fibrillation Treated with Catheter Ablation vs. Antiarrhythmic Drugs

    Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of stroke, heart failure, and death in the general population [ 1 – 4 ]. Catheter ablation (CA) and antiarrhythmic drugs (AADs) are the most commonly employed …

  10. 01-12-2019 | Antiarrhythmic Drugs | OriginalPaper

    A Long-Term Cost-Effectiveness Analysis Comparing Radiofrequency Catheter Ablation with Antiarrhythmic Drugs in Treatment of Chinese Patients with Atrial Fibrillation

    Atrial fibrillation (AF) is the most common cardiac arrhythmia seen in clinical practice and is associated with substantial morbidity and mortality. The lifetime risk of AF between the ages of 40 and 95 years is around 25%, as documented by the …

  11. 01-10-2018 | Events

    If necessary, use antiarrhythmic drugs to treat acute and chronic supraventricular tachycardia in infants

    Supraventricular tachycardia (SVT) is the most common arrhythmia in infants. Older children and adults with SVT are commonly managed with catheter ablation of the SVT substrate; however, such treatment is the last resort in infants because the …

  12. 01-11-2017 | ReviewPaper

    Safety and Interactions of Direct Oral Anticoagulants with Antiarrhythmic Drugs

    Direct oral anticoagulants (DOACs) are novel direct-acting medications that are selective for either thrombin or activated factor X. Due to their obvious benefits for patients (fewer interactions, broader therapeutic window, etc.), they are …

  13. 01-07-1997 | ReviewPaper

    Adverse Effects of Class I Antiarrhythmic Drugs

    Class I antiarrhythmic drugs are characterised by their ability to block the fast inward sodium current in cardiac muscle tissue. However, at the same time, they can be responsible for various effects involving other organs and systems. Although …

  14. 01-06-2010 | ReviewPaper

    Non-Antiarrhythmic Drugs to Prevent Atrial Fibrillation

    Atrial fibrillation (AF) is the most frequent arrhythmia found in clinical practice. The majority of patients with AF are still candidates for antiarrhythmic drug treatment, not only for acute reversion to sinus rhythm but also for long-term …

  15. 01-11-2005 | ReviewPaper

    Antiarrhythmic Drugs in Patients with Implantable Cardioverter-Defibrillators

    Antiarrhythmic drugs need to be initiated in up to 70% of patients with implantable cardioverter-defibrillators (ICDs) in order to treat atrial tachyarrhythmias, decrease the frequency of defibrillator shocks, and terminate ventricular arrhythmias …

  16. 01-05-2003 | ReviewPaper

    Potentially Significant Drug Interactions of Class III Antiarrhythmic Drugs

    Class III antiarrhythmic drugs, especially amiodarone (a broad-spectrum antiarrhythmic agent), have gained popularity for use in clinical practice in recent years. Other class III antiarrhythmic drugs include bretylium, dofetilide, ibutilide and …

  17. 01-04-2002 | ReviewPaper

    Safety of Non-Antiarrhythmic Drugs that Prolong the QT Interval or Induce Torsade de Pointes

    An Overview

    The long and growing list of non-antiarrhythmic drugs associated with prolongation of the QT interval of the electrocardiogram has generated concern not only for regulatory interventions leading to drug withdrawal, but also for the unjustified …

  18. Open Access 01-02-2019 | OriginalPaper

    Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic–clonic seizure model in mice

    Increasing evidence indicates that some antiarrhythmic drugs play a pivotal role in seizures, not only in vivo studies on animals, but also in clinical trials. Some of these antiarrhythmic drugs potentiate or alleviate the anticonvulsant action of …

  19. Open Access 01-12-2017 | ReviewPaper

    Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation

    This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017 . Further information about the Annual …

  20. Open Access 01-12-2017 | Letter

    Antiarrhythmic drugs in out-of-hospital cardiac arrest: is there a place for potassium chloride?

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