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Published in: European Radiology 6/2014

01-06-2014 | Cardiac

Contrast agent bolus tracking with a fixed threshold or a manual fast start for coronary CT angiography

Authors: Fabian Stenzel, Matthias Rief, Elke Zimmermann, Johannes Greupner, Felicitas Richter, Marc Dewey

Published in: European Radiology | Issue 6/2014

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Abstract

Objectives

Comparison of bolus tracking with a fixed threshold versus a manual fast start for coronary CT angiography.

Methods

We retrospectively analysed 320-row coronary CT angiography of 50 patients with suspected or known coronary artery disease. Twenty-five examinations were initiated by a bolus tracking method (group 1), 25 examinations with a manual fast surestart (group 2).

Results

Mean attenuation values in the ascending aorta were 519 ± 111 Hounsfield units (HU) in group 1 and 476 ± 65 HU in group 2 (p = 0.10). Assessable vessel lengths were 171 ± 44 mm vs 172 ± 29 mm for the right coronary artery (p = 0.91), 11 ± 4 mm vs 12 ± 4 mm for the left main (p = 0.9), 163 ± 28 mm vs 151 ± 26 mm for the left anterior descending coronary artery (p = 0.11) and 125 ± 41 mm vs 110 ± 37 mm for the left circumflex coronary artery (p = 0.18). Image quality for all coronary arteries was not significantly different between the groups (p > 0.41). The attenuation ratio between the left and right ventricle was 2.8 ± 0.7 vs 3.6 ± 1.0 (p = 0.003). Significantly less contrast agent was used in group 2 (64 ± 6 ml vs 80 ± 0 ml; p < 0.001).

Conclusions

Bolus tracking with a fixed threshold and with a manual fast start are both suitable methods; the fast start allowed a reduction of contrast agent volumes.

Key Points

Fixed threshold bolus tracking is suitable for coronary 320-row CT angiography
Manual fast start bolus tracking can reduce contrast agent volumes
Manual fast start and fixed threshold initiation achieve good image quality
Fixed threshold bolus tracking achieves a more reliable contrast bolus position
Literature
1.
go back to reference Schuetz GM, Zacharopoulou NM, Schlattmann P, Dewey M (2010) Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging. Ann Intern Med 152:167–177PubMedCrossRef Schuetz GM, Zacharopoulou NM, Schlattmann P, Dewey M (2010) Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging. Ann Intern Med 152:167–177PubMedCrossRef
2.
go back to reference Miller JM, Rochitte CE, Dewey M et al (2008) Diagnostic performance of coronary angiography by 64-row CT. N Engl J Med 359:2324–2336PubMedCrossRef Miller JM, Rochitte CE, Dewey M et al (2008) Diagnostic performance of coronary angiography by 64-row CT. N Engl J Med 359:2324–2336PubMedCrossRef
3.
go back to reference Hamon M, Biondi-Zoccai GG, Malagutti P, Agostoni P, Morello R, Valgimigli M (2006) Diagnostic performance of multislice spiral computed tomography of coronary arteries as compared with conventional invasive coronary angiography: a meta-analysis. J Am Coll Cardiol 48:1896–1910PubMedCrossRef Hamon M, Biondi-Zoccai GG, Malagutti P, Agostoni P, Morello R, Valgimigli M (2006) Diagnostic performance of multislice spiral computed tomography of coronary arteries as compared with conventional invasive coronary angiography: a meta-analysis. J Am Coll Cardiol 48:1896–1910PubMedCrossRef
4.
go back to reference Leschka S, Alkadhi H, Plass A et al (2005) Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J 26:1482–1487PubMedCrossRef Leschka S, Alkadhi H, Plass A et al (2005) Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J 26:1482–1487PubMedCrossRef
5.
go back to reference de Graaf FR, Schuijf JD, van Velzen JE et al (2010) Diagnostic accuracy of 320-row multidetector computed tomography coronary angiography in the non-invasive evaluation of significant coronary artery disease. Eur Heart J 31:1908–1915PubMedCrossRef de Graaf FR, Schuijf JD, van Velzen JE et al (2010) Diagnostic accuracy of 320-row multidetector computed tomography coronary angiography in the non-invasive evaluation of significant coronary artery disease. Eur Heart J 31:1908–1915PubMedCrossRef
6.
go back to reference Budoff MJ, Dowe D, Jollis JG et al (2008) Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am Coll Cardiol 52:1724–1732PubMedCrossRef Budoff MJ, Dowe D, Jollis JG et al (2008) Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am Coll Cardiol 52:1724–1732PubMedCrossRef
7.
go back to reference Dewey M, Borges AC, Kivelitz D et al (2004) Coronary artery disease: new insights and their implications for radiology. Eur Radiol 14:1048–1054PubMedCrossRef Dewey M, Borges AC, Kivelitz D et al (2004) Coronary artery disease: new insights and their implications for radiology. Eur Radiol 14:1048–1054PubMedCrossRef
8.
go back to reference Johnson TR, Nikolaou K, Wintersperger BJ et al (2006) Dual-source CT cardiac imaging: initial experience. Eur Radiol 16:1409–1415PubMedCrossRef Johnson TR, Nikolaou K, Wintersperger BJ et al (2006) Dual-source CT cardiac imaging: initial experience. Eur Radiol 16:1409–1415PubMedCrossRef
9.
go back to reference Klass O, Walker M, Siebach A et al (2010) Prospectively gated axial CT coronary angiography: comparison of image quality and effective radiation dose between 64- and 256-slice CT. Eur Radiol 20:1124–1131PubMedCrossRef Klass O, Walker M, Siebach A et al (2010) Prospectively gated axial CT coronary angiography: comparison of image quality and effective radiation dose between 64- and 256-slice CT. Eur Radiol 20:1124–1131PubMedCrossRef
10.
go back to reference Pugliese F, Mollet NR, Runza G et al (2006) Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris. Eur Radiol 16:575–582PubMedCrossRef Pugliese F, Mollet NR, Runza G et al (2006) Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris. Eur Radiol 16:575–582PubMedCrossRef
11.
go back to reference Leschka S, Wildermuth S, Boehm T et al (2006) Noninvasive coronary angiography with 64-section CT: effect of average heart rate and heart rate variability on image quality. Radiology 241:378–385PubMedCrossRef Leschka S, Wildermuth S, Boehm T et al (2006) Noninvasive coronary angiography with 64-section CT: effect of average heart rate and heart rate variability on image quality. Radiology 241:378–385PubMedCrossRef
12.
go back to reference Dewey M, Teige F, Laule M, Hamm B (2007) Influence of heart rate on diagnostic accuracy and image quality of 16-slice CT coronary angiography: comparison of multisegment and halfscan reconstruction approaches. Eur Radiol 17:2829–2837PubMedCrossRef Dewey M, Teige F, Laule M, Hamm B (2007) Influence of heart rate on diagnostic accuracy and image quality of 16-slice CT coronary angiography: comparison of multisegment and halfscan reconstruction approaches. Eur Radiol 17:2829–2837PubMedCrossRef
13.
go back to reference Dewey M, Vavere AL, Arbab-Zadeh A et al (2010) Patient characteristics as predictors of image quality and diagnostic accuracy of MDCT compared with conventional coronary angiography for detecting coronary artery stenoses: CORE-64 Multicenter International Trial. AJR Am J Roentgenol 194:93–102PubMedCentralPubMedCrossRef Dewey M, Vavere AL, Arbab-Zadeh A et al (2010) Patient characteristics as predictors of image quality and diagnostic accuracy of MDCT compared with conventional coronary angiography for detecting coronary artery stenoses: CORE-64 Multicenter International Trial. AJR Am J Roentgenol 194:93–102PubMedCentralPubMedCrossRef
14.
go back to reference Schnapauff D, Teige F, Hamm B, Dewey M (2009) Comparison between the image quality of multisegment and halfscan reconstructions of non-invasive CT coronary angiography. Br J Radiol 82:969–975PubMedCentralPubMedCrossRef Schnapauff D, Teige F, Hamm B, Dewey M (2009) Comparison between the image quality of multisegment and halfscan reconstructions of non-invasive CT coronary angiography. Br J Radiol 82:969–975PubMedCentralPubMedCrossRef
15.
go back to reference Tomizawa N, Nojo T, Akahane M, Torigoe R, Kiryu S, Ohtomo K (2013) Shorter delay time reduces interpatient variability in coronary enhancement in coronary CT angiography using the bolus tracking method with 320-row CT. Int J Cardiovasc Imaging. doi:10.1007/s10554-012-0045-1 Tomizawa N, Nojo T, Akahane M, Torigoe R, Kiryu S, Ohtomo K (2013) Shorter delay time reduces interpatient variability in coronary enhancement in coronary CT angiography using the bolus tracking method with 320-row CT. Int J Cardiovasc Imaging. doi:10.​1007/​s10554-012-0045-1
16.
go back to reference Cademartiri F, de Monye C, Pugliese F et al (2006) High iodine concentration contrast material for noninvasive multislice computed tomography coronary angiography: iopromide 370 versus iomeprol 400. Invest Radiol 41:349–353PubMedCrossRef Cademartiri F, de Monye C, Pugliese F et al (2006) High iodine concentration contrast material for noninvasive multislice computed tomography coronary angiography: iopromide 370 versus iomeprol 400. Invest Radiol 41:349–353PubMedCrossRef
17.
go back to reference Cademartiri F, Mollet NR, van der Lugt A et al (2005) Intravenous contrast material administration at helical 16-detector row CT coronary angiography: effect of iodine concentration on vascular attenuation. Radiology 236:661–665PubMedCrossRef Cademartiri F, Mollet NR, van der Lugt A et al (2005) Intravenous contrast material administration at helical 16-detector row CT coronary angiography: effect of iodine concentration on vascular attenuation. Radiology 236:661–665PubMedCrossRef
18.
go back to reference Cademartiri F, van der Lugt A, Luccichenti G, Pavone P, Krestin GP (2002) Parameters affecting bolus geometry in CTA: a review. J Comput Assist Tomogr 26:598–607PubMedCrossRef Cademartiri F, van der Lugt A, Luccichenti G, Pavone P, Krestin GP (2002) Parameters affecting bolus geometry in CTA: a review. J Comput Assist Tomogr 26:598–607PubMedCrossRef
19.
go back to reference Lell M, Marwan M, Schepis T et al (2009) Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience. Eur Radiol 19:2576–2583PubMedCrossRef Lell M, Marwan M, Schepis T et al (2009) Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience. Eur Radiol 19:2576–2583PubMedCrossRef
20.
go back to reference Seifarth H, Puesken M, Kalafut JF et al (2009) Introduction of an individually optimized protocol for the injection of contrast medium for coronary CT angiography. Eur Radiol 19:2373–2382PubMedCrossRef Seifarth H, Puesken M, Kalafut JF et al (2009) Introduction of an individually optimized protocol for the injection of contrast medium for coronary CT angiography. Eur Radiol 19:2373–2382PubMedCrossRef
21.
go back to reference Tomizawa N, Nojo T, Akahane M, Torigoe R, Kiryu S, Ohtomo K (2012) Prediction of the attenuation of the ascending aorta using bolus-tracking parameters and heart rate in coronary computed tomography angiography. Eur J Radiol. doi:10.1016/j.ejrad.2012.02.001 Tomizawa N, Nojo T, Akahane M, Torigoe R, Kiryu S, Ohtomo K (2012) Prediction of the attenuation of the ascending aorta using bolus-tracking parameters and heart rate in coronary computed tomography angiography. Eur J Radiol. doi:10.​1016/​j.​ejrad.​2012.​02.​001
22.
go back to reference Bae KT (2010) Intravenous contrast medium administration and scan timing at CT: considerations and approaches. Radiology 256:32–61PubMedCrossRef Bae KT (2010) Intravenous contrast medium administration and scan timing at CT: considerations and approaches. Radiology 256:32–61PubMedCrossRef
23.
go back to reference Rybicki FJ, Otero HJ, Steigner ML et al (2008) Initial evaluation of coronary images from 320-detector row computed tomography. Int J Cardiovasc Imaging 24:535–546PubMedCrossRef Rybicki FJ, Otero HJ, Steigner ML et al (2008) Initial evaluation of coronary images from 320-detector row computed tomography. Int J Cardiovasc Imaging 24:535–546PubMedCrossRef
24.
go back to reference de Graaf FR, Schuijf JD, van Velzen JE et al (2010) Diagnostic accuracy of 320-row multidetector computed tomography coronary angiography to noninvasively assess in-stent restenosis. Invest Radiol 45:331–340PubMed de Graaf FR, Schuijf JD, van Velzen JE et al (2010) Diagnostic accuracy of 320-row multidetector computed tomography coronary angiography to noninvasively assess in-stent restenosis. Invest Radiol 45:331–340PubMed
25.
go back to reference Dewey M, Muller M, Teige F, Hamm B (2006) Evaluation of a semiautomatic software tool for left ventricular function analysis with 16-slice computed tomography. Eur Radiol 16:25–31PubMedCrossRef Dewey M, Muller M, Teige F, Hamm B (2006) Evaluation of a semiautomatic software tool for left ventricular function analysis with 16-slice computed tomography. Eur Radiol 16:25–31PubMedCrossRef
27.
go back to reference Dewey M, Zimmermann E, Deissenrieder F et al (2009) Noninvasive coronary angiography by 320-row computed tomography with lower radiation exposure and maintained diagnostic accuracy: comparison of results with cardiac catheterization in a head-to-head pilot investigation. Circulation 120:867–875PubMedCrossRef Dewey M, Zimmermann E, Deissenrieder F et al (2009) Noninvasive coronary angiography by 320-row computed tomography with lower radiation exposure and maintained diagnostic accuracy: comparison of results with cardiac catheterization in a head-to-head pilot investigation. Circulation 120:867–875PubMedCrossRef
28.
go back to reference Dewey M, Hoffmann H, Hamm B (2006) Multislice CT coronary angiography: effect of sublingual nitroglycerine on the diameter of coronary arteries. Rofo 178:600–604PubMedCrossRef Dewey M, Hoffmann H, Hamm B (2006) Multislice CT coronary angiography: effect of sublingual nitroglycerine on the diameter of coronary arteries. Rofo 178:600–604PubMedCrossRef
29.
go back to reference Dewey M, Schnapauff D, Laule M et al (2004) Multislice CT coronary angiography: evaluation of an automatic vessel detection tool. Rofo 176:478–483PubMedCrossRef Dewey M, Schnapauff D, Laule M et al (2004) Multislice CT coronary angiography: evaluation of an automatic vessel detection tool. Rofo 176:478–483PubMedCrossRef
30.
go back to reference Zhu X, Chen W, Li M et al (2012) Contrast material injection protocol with the flow rate adjusted to the heart rate for dual source CT coronary angiography. Int J Cardiovasc Imaging 28:1557–1565PubMedCrossRef Zhu X, Chen W, Li M et al (2012) Contrast material injection protocol with the flow rate adjusted to the heart rate for dual source CT coronary angiography. Int J Cardiovasc Imaging 28:1557–1565PubMedCrossRef
31.
go back to reference Becker CR, Hong C, Knez A et al (2003) Optimal contrast application for cardiac 4-detector-row computed tomography. Invest Radiol 38:690–694PubMedCrossRef Becker CR, Hong C, Knez A et al (2003) Optimal contrast application for cardiac 4-detector-row computed tomography. Invest Radiol 38:690–694PubMedCrossRef
32.
go back to reference Yang WJ, Chen KM, Liu B et al (2013) Contrast media volume optimization in high-pitch dual-source CT coronary angiography: feasibility study. Int J Cardiovasc Imaging 29:245–252PubMedCrossRef Yang WJ, Chen KM, Liu B et al (2013) Contrast media volume optimization in high-pitch dual-source CT coronary angiography: feasibility study. Int J Cardiovasc Imaging 29:245–252PubMedCrossRef
33.
go back to reference La Grutta L, Galia M, Gentile G et al (2013) Comparison of iodinated contrast media for the assessment of atherosclerotic plaque attenuation values by CT coronary angiography: observations in an ex vivo model. Br J Radiol 86:20120238PubMedCrossRef La Grutta L, Galia M, Gentile G et al (2013) Comparison of iodinated contrast media for the assessment of atherosclerotic plaque attenuation values by CT coronary angiography: observations in an ex vivo model. Br J Radiol 86:20120238PubMedCrossRef
34.
go back to reference Cademartiri F, Mollet NR, van der Lugt A et al (2005) Intravenous contrast material administration at helical 16-detector row CT coronary angiography: effect of iodine concentration on vascular attenuation. Radiology 236:661–665PubMedCrossRef Cademartiri F, Mollet NR, van der Lugt A et al (2005) Intravenous contrast material administration at helical 16-detector row CT coronary angiography: effect of iodine concentration on vascular attenuation. Radiology 236:661–665PubMedCrossRef
35.
go back to reference Mühlenbruch G, Behrendt F, Eddahabi M et al (2008) Which iodine concentration in chest CT? – A prospective study in 300 patients. Eur Radiol 18:2826–2832PubMedCrossRef Mühlenbruch G, Behrendt F, Eddahabi M et al (2008) Which iodine concentration in chest CT? – A prospective study in 300 patients. Eur Radiol 18:2826–2832PubMedCrossRef
36.
go back to reference Rubin GD, Lane MJ, Bloch DA, Leung AN, Stark P (1996) Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration. Radiology 201:785–791PubMed Rubin GD, Lane MJ, Bloch DA, Leung AN, Stark P (1996) Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration. Radiology 201:785–791PubMed
37.
go back to reference Cademartiri F, Nieman K, van der Lugt A et al (2004) Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique. Radiology 233:817–823PubMedCrossRef Cademartiri F, Nieman K, van der Lugt A et al (2004) Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique. Radiology 233:817–823PubMedCrossRef
38.
go back to reference Ramos-Duran LR, Kalafut JF, Hanley M, Schoepf UJ (2010) Current contrast media delivery strategies for cardiac and pulmonary multidetector-row computed tomography angiography. J Thorac Imaging 25:270–277PubMedCrossRef Ramos-Duran LR, Kalafut JF, Hanley M, Schoepf UJ (2010) Current contrast media delivery strategies for cardiac and pulmonary multidetector-row computed tomography angiography. J Thorac Imaging 25:270–277PubMedCrossRef
39.
go back to reference Johnson TR, Nikolaou K, Wintersperger BJ et al (2007) Optimization of contrast material administration for electrocardiogram-gated computed tomographic angiography of the chest. J Comput Assist Tomogr 31:265–271PubMedCrossRef Johnson TR, Nikolaou K, Wintersperger BJ et al (2007) Optimization of contrast material administration for electrocardiogram-gated computed tomographic angiography of the chest. J Comput Assist Tomogr 31:265–271PubMedCrossRef
40.
go back to reference Cademartiri F, Mollet NR, Lemos PA et al (2006) Higher intracoronary attenuation improves diagnostic accuracy in MDCT coronary angiography. AJR Am J Roentgenol 187:W430–433PubMedCrossRef Cademartiri F, Mollet NR, Lemos PA et al (2006) Higher intracoronary attenuation improves diagnostic accuracy in MDCT coronary angiography. AJR Am J Roentgenol 187:W430–433PubMedCrossRef
41.
go back to reference Fei X, Du X, Yang Q et al (2008) 64-MDCT coronary angiography: phantom study of effects of vascular attenuation on detection of coronary stenosis. AJR Am J Roentgenol 191:43–49PubMedCrossRef Fei X, Du X, Yang Q et al (2008) 64-MDCT coronary angiography: phantom study of effects of vascular attenuation on detection of coronary stenosis. AJR Am J Roentgenol 191:43–49PubMedCrossRef
42.
go back to reference Tonino PA, De Bruyne B, Pijls NH et al (2009) Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 360:213–224PubMedCrossRef Tonino PA, De Bruyne B, Pijls NH et al (2009) Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 360:213–224PubMedCrossRef
43.
go back to reference De Bruyne B, Pijls NH, Kalesan B et al (2012) Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med 367:991–1001PubMedCrossRef De Bruyne B, Pijls NH, Kalesan B et al (2012) Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med 367:991–1001PubMedCrossRef
44.
go back to reference Min JK, Leipsic J, Pencina MJ et al (2012) Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. JAMA 308:1237–1245PubMedCrossRef Min JK, Leipsic J, Pencina MJ et al (2012) Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. JAMA 308:1237–1245PubMedCrossRef
45.
go back to reference Yoon YE, Choi JH, Kim JH et al (2012) Noninvasive diagnosis of ischemia-causing coronary stenosis using CT angiography: diagnostic value of transluminal attenuation gradient and fractional flow reserve computed from coronary CT angiography compared to invasively measured fractional flow reserve. JACC Cardiovasc Imaging 5:1088–1096PubMedCrossRef Yoon YE, Choi JH, Kim JH et al (2012) Noninvasive diagnosis of ischemia-causing coronary stenosis using CT angiography: diagnostic value of transluminal attenuation gradient and fractional flow reserve computed from coronary CT angiography compared to invasively measured fractional flow reserve. JACC Cardiovasc Imaging 5:1088–1096PubMedCrossRef
46.
go back to reference Koo BK, Erglis A, Doh JH et al (2011) Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study. J Am Coll Cardiol 58:1989–1997PubMedCrossRef Koo BK, Erglis A, Doh JH et al (2011) Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study. J Am Coll Cardiol 58:1989–1997PubMedCrossRef
47.
go back to reference Steigner ML, Mitsouras D, Whitmore AG et al (2010) Iodinated contrast opacification gradients in normal coronary arteries imaged with prospectively ECG-gated single heart beat 320-detector row computed tomography. Circ Cardiovasc Imaging 3:179–186PubMedCentralPubMedCrossRef Steigner ML, Mitsouras D, Whitmore AG et al (2010) Iodinated contrast opacification gradients in normal coronary arteries imaged with prospectively ECG-gated single heart beat 320-detector row computed tomography. Circ Cardiovasc Imaging 3:179–186PubMedCentralPubMedCrossRef
48.
go back to reference Choi JH, Koo BK, Yoon YE et al (2012) Diagnostic performance of intracoronary gradient-based methods by coronary computed tomography angiography for the evaluation of physiologically significant coronary artery stenoses: a validation study with fractional flow reserve. Eur Heart J Cardiovasc Imaging 13:1001–1007PubMedCrossRef Choi JH, Koo BK, Yoon YE et al (2012) Diagnostic performance of intracoronary gradient-based methods by coronary computed tomography angiography for the evaluation of physiologically significant coronary artery stenoses: a validation study with fractional flow reserve. Eur Heart J Cardiovasc Imaging 13:1001–1007PubMedCrossRef
49.
go back to reference Choi JH, Min JK, Labounty TM et al (2011) Intracoronary transluminal attenuation gradient in coronary CT angiography for determining coronary artery stenosis. JACC Cardiovasc Imaging 4:1149–1157PubMedCrossRef Choi JH, Min JK, Labounty TM et al (2011) Intracoronary transluminal attenuation gradient in coronary CT angiography for determining coronary artery stenosis. JACC Cardiovasc Imaging 4:1149–1157PubMedCrossRef
50.
go back to reference Wong DT, Ko BS, Cameron JD et al (2013) Transluminal attenuation gradient in coronary computed tomography angiography is a novel noninvasive approach to the identification of functionally significant coronary artery stenosis: a comparison with fractional flow reserve. J Am Coll Cardiol 61:1271–1279PubMedCrossRef Wong DT, Ko BS, Cameron JD et al (2013) Transluminal attenuation gradient in coronary computed tomography angiography is a novel noninvasive approach to the identification of functionally significant coronary artery stenosis: a comparison with fractional flow reserve. J Am Coll Cardiol 61:1271–1279PubMedCrossRef
51.
go back to reference Cademartiri F, Mollet N, van der Lugt A et al (2004) Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser. Eur Radiol 14:178–183PubMedCrossRef Cademartiri F, Mollet N, van der Lugt A et al (2004) Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser. Eur Radiol 14:178–183PubMedCrossRef
52.
go back to reference Kim DJ, Kim TH, Kim SJ et al (2008) Saline flush effect for enhancement of aorta and coronary arteries at multidetector CT coronary angiography. Radiology 246:110–115PubMedCrossRef Kim DJ, Kim TH, Kim SJ et al (2008) Saline flush effect for enhancement of aorta and coronary arteries at multidetector CT coronary angiography. Radiology 246:110–115PubMedCrossRef
Metadata
Title
Contrast agent bolus tracking with a fixed threshold or a manual fast start for coronary CT angiography
Authors
Fabian Stenzel
Matthias Rief
Elke Zimmermann
Johannes Greupner
Felicitas Richter
Marc Dewey
Publication date
01-06-2014
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 6/2014
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3148-3

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