Skip to main content
Top
Published in: European Radiology 1/2006

01-01-2006 | Cardiac

Evaluation of a semiautomatic software tool for left ventricular function analysis with 16-slice computed tomography

Authors: Marc Dewey, Mira Müller, Florian Teige, Bernd Hamm

Published in: European Radiology | Issue 1/2006

Login to get access

Abstract

The purpose of the study was to evaluate a semiautomatic analysis tool for assessing global left ventricular myocardial function with multislice computed tomography (MSCT). We examined 33 patients with MSCT using 16×0.5 mm detector collimation and magnetic resonance imaging (MRI) on a 1.5-T scanner. MSCT data were analyzed using semiautomatic volumetric analysis software (ANET, CSCF-001A, Toshiba). This software tool automatically creates endo- and epicardial contours that can be manually corrected on all short-axis slices at all reconstructed time points within the cardiac cycle, based on a contour-detection and density-threshold algorithm. All global left ventricular function parameters assessed with the semiautomatic MSCT software were highly correlated with the results of MRI. Bland-Altman analysis showed minor systematic overestimation of end-diastolic (10.7 ml) and end-systolic volumes (5.6 ml) and underestimation of ejection fraction (2.1%) with MSCT as compared with MRI. The post-processing time was moderately but significantly longer with the MSCT software (15.9±2.8 min) than necessary for MRI (14.0±2.5 min, P<0.01), mainly as a result of the longer time required for uploading of the MSCT datasets, which were on average 54 times larger (1.3 GByte). In conclusion, it appears feasible to accurately assess global left ventricular function with MSCT in a reasonable post-processing time using a semiautomatic software tool.
Literature
1.
go back to reference Kopp AF, Küttner A, Trabold T, Heuschmid M, Schröder S, Claussen CD (2003) MDCT: cardiology indications. Eur Radiol 13(Suppl 5):M102–M115PubMed Kopp AF, Küttner A, Trabold T, Heuschmid M, Schröder S, Claussen CD (2003) MDCT: cardiology indications. Eur Radiol 13(Suppl 5):M102–M115PubMed
2.
go back to reference Nikolaou K, Sagmeister S, Knez A et al (2003) Multidetector-row computed tomography of the coronary arteries: predictive value and quantitative assessment of non-calcified vessel-wall changes. Eur Radiol 13:2505–2512CrossRefPubMed Nikolaou K, Sagmeister S, Knez A et al (2003) Multidetector-row computed tomography of the coronary arteries: predictive value and quantitative assessment of non-calcified vessel-wall changes. Eur Radiol 13:2505–2512CrossRefPubMed
3.
go back to reference Rodenwaldt J (2003) Multislice computed tomography of the coronary arteries. Eur Radiol 13:748–757PubMed Rodenwaldt J (2003) Multislice computed tomography of the coronary arteries. Eur Radiol 13:748–757PubMed
4.
go back to reference Juergens KU, Grude M, Maintz D et al (2004) Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience. Radiology 230:403–410PubMed Juergens KU, Grude M, Maintz D et al (2004) Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience. Radiology 230:403–410PubMed
5.
go back to reference Mahnken AH, Spuntrup E, Wildberger JE et al (2003) Quantification of cardiac function with multislice spiral CT using retrospective EKG-gating: comparison with MRI. Fortschr Röntgenstr 175:83–88CrossRef Mahnken AH, Spuntrup E, Wildberger JE et al (2003) Quantification of cardiac function with multislice spiral CT using retrospective EKG-gating: comparison with MRI. Fortschr Röntgenstr 175:83–88CrossRef
6.
go back to reference Grude M, Juergens KU, Wichter T et al (2003) Evaluation of global left ventricular myocardial function with electrocardiogram-gated multidetector computed tomography: comparison with magnetic resonance imaging. Invest Radiol 38:653–661PubMed Grude M, Juergens KU, Wichter T et al (2003) Evaluation of global left ventricular myocardial function with electrocardiogram-gated multidetector computed tomography: comparison with magnetic resonance imaging. Invest Radiol 38:653–661PubMed
7.
go back to reference Heuschmid M, Rothfuss J, Schröder S et al (2005) Left ventricular functional parameters: comparison of 16-slice spiral CT and MRI. Röfo 177:60–66PubMed Heuschmid M, Rothfuss J, Schröder S et al (2005) Left ventricular functional parameters: comparison of 16-slice spiral CT and MRI. Röfo 177:60–66PubMed
8.
go back to reference The Multicenter Postinfarction Research Group (1983) Risk stratification and survival after myocardial infarction. N Engl J Med 309:331–336 The Multicenter Postinfarction Research Group (1983) Risk stratification and survival after myocardial infarction. N Engl J Med 309:331–336
9.
go back to reference Hammermeister KE, DeRouen TA, Dodge HT (1979) Variables predictive of survival in patients with coronary disease. Selection by univariate and multivariate analyses from the clinical, electrocardiographic, exercise, arteriographic, and quantitative angiographic evaluations. Circulation 59:421–430PubMed Hammermeister KE, DeRouen TA, Dodge HT (1979) Variables predictive of survival in patients with coronary disease. Selection by univariate and multivariate analyses from the clinical, electrocardiographic, exercise, arteriographic, and quantitative angiographic evaluations. Circulation 59:421–430PubMed
10.
go back to reference Boehm T, Alkadhi H, Roffi M et al (2004) Time-effectiveness, observer-dependence, and accuracy of measurements of left ventricular ejection fraction using 4-channel MDCT. Röfo 176:529–537PubMed Boehm T, Alkadhi H, Roffi M et al (2004) Time-effectiveness, observer-dependence, and accuracy of measurements of left ventricular ejection fraction using 4-channel MDCT. Röfo 176:529–537PubMed
11.
go back to reference Frericks BB, Caldarone FC, Nashan B et al (2004) 3D CT modeling of hepatic vessel architecture and volume calculation in living donated liver transplantation. Eur Radiol 14:326–333CrossRefPubMed Frericks BB, Caldarone FC, Nashan B et al (2004) 3D CT modeling of hepatic vessel architecture and volume calculation in living donated liver transplantation. Eur Radiol 14:326–333CrossRefPubMed
12.
go back to reference Neri E, Bargellini I, Rieger M et al (2005) Abdominal aortic aneurysms: virtual imaging and analysis through a remote web server. Eur Radiol 15:348–352CrossRefPubMed Neri E, Bargellini I, Rieger M et al (2005) Abdominal aortic aneurysms: virtual imaging and analysis through a remote web server. Eur Radiol 15:348–352CrossRefPubMed
13.
go back to reference Dewey M, Schnapauff D, Laule M et al (2004) Multislice CT coronary angiography: evaluation of an automatic vessel detection tool. Fortschr Röntgenstr 176:478–483 Dewey M, Schnapauff D, Laule M et al (2004) Multislice CT coronary angiography: evaluation of an automatic vessel detection tool. Fortschr Röntgenstr 176:478–483
14.
go back to reference Wessling J, Fischbach R, Domagk D, Lugering N, Neumann E, Heindel W (2001) Colorectal polyps: detection with multi-slice CT colonography. Fortschr Röntgenstr 173:1069–1071CrossRef Wessling J, Fischbach R, Domagk D, Lugering N, Neumann E, Heindel W (2001) Colorectal polyps: detection with multi-slice CT colonography. Fortschr Röntgenstr 173:1069–1071CrossRef
15.
go back to reference Zhang Z, Berg MH, Ikonen AE, Vanninen RL, Manninen HI (2004) Carotid artery stenosis: reproducibility of automated 3D CT angiography analysis method. Eur Radiol 14:665–672CrossRefPubMed Zhang Z, Berg MH, Ikonen AE, Vanninen RL, Manninen HI (2004) Carotid artery stenosis: reproducibility of automated 3D CT angiography analysis method. Eur Radiol 14:665–672CrossRefPubMed
16.
go back to reference Dewey M, Laule M, Krug L et al (2004) Multisegment and halfscan reconstruction of 16-slice computed tomography for detection of coronary artery stenoses. Invest Radiol 39:223–229CrossRefPubMed Dewey M, Laule M, Krug L et al (2004) Multisegment and halfscan reconstruction of 16-slice computed tomography for detection of coronary artery stenoses. Invest Radiol 39:223–229CrossRefPubMed
17.
go back to reference Aspelin P, Aubry P, Fransson SG, Strasser R, Willenbrock R, Berg KJ (2003) Nephrotoxic effects in high-risk patients undergoing angiography. N Engl J Med 348:491–499CrossRefPubMed Aspelin P, Aubry P, Fransson SG, Strasser R, Willenbrock R, Berg KJ (2003) Nephrotoxic effects in high-risk patients undergoing angiography. N Engl J Med 348:491–499CrossRefPubMed
18.
go back to reference Koch K, Oellig F, Kunz P et al (2004) Assessment of global and regional left ventricular function with a 16-slice spiral-CT using two different software tools for quantitative functional analysis and qualitative evaluation of wall motion changes in comparison with magnetic resonance imaging. Röfo 176:1786–1793PubMed Koch K, Oellig F, Kunz P et al (2004) Assessment of global and regional left ventricular function with a 16-slice spiral-CT using two different software tools for quantitative functional analysis and qualitative evaluation of wall motion changes in comparison with magnetic resonance imaging. Röfo 176:1786–1793PubMed
19.
go back to reference Yamaoka O, Yabe T, Okada M et al (1993) Evaluation of left ventricular mass: comparison of ultrafast computed tomography, magnetic resonance imaging, and contrast left ventriculography. Am Heart J 126:1372–1379CrossRefPubMed Yamaoka O, Yabe T, Okada M et al (1993) Evaluation of left ventricular mass: comparison of ultrafast computed tomography, magnetic resonance imaging, and contrast left ventriculography. Am Heart J 126:1372–1379CrossRefPubMed
20.
go back to reference Lorenz CH, Walker ES, Morgan VL, Klein SS, Graham TP Jr (1999) Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. J Cardiovasc Magn Reson 1:7–21 Lorenz CH, Walker ES, Morgan VL, Klein SS, Graham TP Jr (1999) Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. J Cardiovasc Magn Reson 1:7–21
21.
go back to reference Wintersperger BJ, Nikolaou K, Dietrich O et al (2003) Single breath-hold real-time cine MR imaging: improved temporal resolution using generalized autocalibrating partially parallel acquisition (GRAPPA) algorithm. Eur Radiol 13:1931–1936CrossRefPubMed Wintersperger BJ, Nikolaou K, Dietrich O et al (2003) Single breath-hold real-time cine MR imaging: improved temporal resolution using generalized autocalibrating partially parallel acquisition (GRAPPA) algorithm. Eur Radiol 13:1931–1936CrossRefPubMed
22.
go back to reference Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMed Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMed
23.
go back to reference Stamm G, Nagel HD (2002) CT-expo–a novel program for dose evaluation in CT. Fortschr Röntgenstr 174:1570–1576CrossRef Stamm G, Nagel HD (2002) CT-expo–a novel program for dose evaluation in CT. Fortschr Röntgenstr 174:1570–1576CrossRef
24.
go back to reference Crawford MH, Souchek J, Oprian CA et al (1990) Determinants of survival and left ventricular performance after mitral valve replacement. Department of Veterans Affairs Cooperative Study on Valvular Heart Disease. Circulation 81:1173–1181PubMed Crawford MH, Souchek J, Oprian CA et al (1990) Determinants of survival and left ventricular performance after mitral valve replacement. Department of Veterans Affairs Cooperative Study on Valvular Heart Disease. Circulation 81:1173–1181PubMed
25.
go back to reference Borow KM, Green LH, Mann T et al (1980) End-systolic volume as a predictor of postoperative left ventricular performance in volume overload from valvular regurgitation. Am J Med 68:655–663CrossRefPubMed Borow KM, Green LH, Mann T et al (1980) End-systolic volume as a predictor of postoperative left ventricular performance in volume overload from valvular regurgitation. Am J Med 68:655–663CrossRefPubMed
26.
go back to reference White HD, Norris RM, Brown MA, Brandt PW, Whitlock RM, Wild CJ (1987) Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 76:44–51PubMed White HD, Norris RM, Brown MA, Brandt PW, Whitlock RM, Wild CJ (1987) Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 76:44–51PubMed
27.
go back to reference Juergens KU, Maintz D, Grude M et al (2005) Multi-detector row computed tomography of the heart: does a multi-segment reconstruction algorithm improve left ventricular volume measurements? Eur Radiol 15:111–117CrossRefPubMed Juergens KU, Maintz D, Grude M et al (2005) Multi-detector row computed tomography of the heart: does a multi-segment reconstruction algorithm improve left ventricular volume measurements? Eur Radiol 15:111–117CrossRefPubMed
28.
go back to reference Mahnken AH, Spuentrup E, Niethammer M et al (2003) Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI. Acta Radiol 44:604–611PubMed Mahnken AH, Spuentrup E, Niethammer M et al (2003) Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI. Acta Radiol 44:604–611PubMed
29.
go back to reference Yamamuro M, Tadamura E, Kubo S et al (2005) Cardiac functional analysis with multi-detector row CT and segmental reconstruction algorithm: comparison with echocardiography, SPECT, and MR imaging. Radiology 234:381–390PubMed Yamamuro M, Tadamura E, Kubo S et al (2005) Cardiac functional analysis with multi-detector row CT and segmental reconstruction algorithm: comparison with echocardiography, SPECT, and MR imaging. Radiology 234:381–390PubMed
30.
go back to reference Koch K, Oellig F, Oberholzer K et al (2005) Assessment of right ventricular function by 16-detector-row CT: comparison with magnetic resonance imaging. Eur Radiol 15:312–318CrossRefPubMed Koch K, Oellig F, Oberholzer K et al (2005) Assessment of right ventricular function by 16-detector-row CT: comparison with magnetic resonance imaging. Eur Radiol 15:312–318CrossRefPubMed
Metadata
Title
Evaluation of a semiautomatic software tool for left ventricular function analysis with 16-slice computed tomography
Authors
Marc Dewey
Mira Müller
Florian Teige
Bernd Hamm
Publication date
01-01-2006
Publisher
Springer-Verlag
Published in
European Radiology / Issue 1/2006
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-005-2817-7

Other articles of this Issue 1/2006

European Radiology 1/2006 Go to the issue