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01-02-2004 | Cardiac

Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser

Authors: Filippo Cademartiri, Nico Mollet, Aad van der Lugt, Koen Nieman, Peter M. T. Pattynama, Pim J. de Feyter, Gabriel P. Krestin

Published in: European Radiology | Issue 2/2004

Abstract

The aim of this study was to investigate the usefulness of saline chaser in 16-row multislice CT (16-MSCT) coronary angiography. Forty-two patients were divided into two groups for contrast material (CM) administration: group 1 (140 ml at 4 ml/s) and group 2 (100 ml at 4 ml/s followed by 40 ml of saline chaser at 4 ml/s). All patients underwent retrospectively ECG-gated 16-MSCT coronary angiography. The attenuation at the origin coronary vessels was assessed. Three regions of interest (ROIs) were drawn throughout the data set: (a) ascending aorta (ROI 1); (b) descending aorta (ROI 2); and (c) pulmonary artery (ROI 3). The attenuation in the superior vena cava was recorded (ROI 4). The average attenuation and the slope were calculated in each ROI and differences were assessed with a Student’s t test. The average attenuation in the coronary vessels was not significantly different in the two groups. The average attenuations in ROI 1 were 325 and 327 HU, in ROI 2 were 328 and 329 HU and in ROI 3 were 357 and 320 HU, for groups 1 and 2, respectively (p>0.05). The slopes in ROI 1 were −0.2 and 1.1, in ROI 2 were 2.8 and 2.1 (p>0.05) and in ROI3 were 3.9 and −9.0 (p<0.05), for groups 1 and 2, respectively. The average attenuations in ROI 4 were 927 and 643 HU (p<0.05), for groups 1 and 2, respectively. One hundred milliliters of CM with 40 ml of saline chaser provides the same attenuation as 140 ml of CM (35% less) with decreased hyper-attenuation in the superior vena cava.

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Title: Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser
Authors: Filippo Cademartiri
Nico Mollet
Aad van der Lugt
Koen Nieman
Peter M. T. Pattynama
Pim J. de Feyter
Gabriel P. Krestin
Publication date: 01-02-2004
Publisher: Springer-Verlag
Published in: European Radiology / Issue 2/2004
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-003-2188-x

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Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser

Abstract

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