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Published in: Rheumatology International 11/2008

01-09-2008 | Original Article

Significance of risk factors for osteoporosis is dependent on gender and menopause in rheumatoid arthritis

Authors: Peter Oelzner, Antje Schwabe, Gabriele Lehmann, Thorsten Eidner, Sybille Franke, Gunter Wolf, Gert Hein

Published in: Rheumatology International | Issue 11/2008

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Abstract

The aim of our study was to compare the significance of risk factors for osteoporosis according to gender and menopausal state in patients with rheumatoid arthritis (RA). Bone mineral density (dual X-ray absorptiometry), cumulative glucocorticoid dose, age, disease duration, body mass index (BMI) and parameters of disease activity and bone turnover were registered in 343 postmenopausal women, 100 premenopausal women and 108 men with RA. Osteoporosis was found in a significantly higher percentage in postmenopausal women (55.7%) and in men (50.5%) in comparison with premenopausal women (18%; P < 0.001). The following risk factors for osteoporosis were found: older age, low BMI and high cumulative glucocorticoid dose in postmenopausal women, low BMI and high cumulative glucocorticoid dose in men and low BMI in premenopausal women. There is a very high prevalence of osteoporosis not only in postmenopausal women but also in men with RA. Osteoporosis risk factors are strongly dependent from gender and menopausal state.
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Metadata
Title
Significance of risk factors for osteoporosis is dependent on gender and menopause in rheumatoid arthritis
Authors
Peter Oelzner
Antje Schwabe
Gabriele Lehmann
Thorsten Eidner
Sybille Franke
Gunter Wolf
Gert Hein
Publication date
01-09-2008
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 11/2008
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-008-0576-x

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