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01-06-2007 | Review

The remission of rheumatoid arthritis during pregnancy

Authors: Monika Østensen, Peter M. Villiger

Published in: Seminars in Immunopathology | Issue 2/2007

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease that is favorably influenced by pregnancy but relapses after delivery. A variety of circulating factors has been considered as candidates for inducing gestational improvement of RA; however, the factors/pathways responsible remain still elusive. This review discusses recent research on the effect of pregnancy on RA with a focus on immunregulation, cytokine secretion, HLA antigens, microchimerism, and innate immunity. The complex hormonal and immunological alterations of pregnancy may temporarily correct the disturbed immunregulation of RA.

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Title: The remission of rheumatoid arthritis during pregnancy
Authors: Monika Østensen
Peter M. Villiger
Publication date: 01-06-2007
Publisher: Springer-Verlag
Published in: Seminars in Immunopathology / Issue 2/2007
Print ISSN: 1863-2297
Electronic ISSN: 1863-2300
DOI: https://doi.org/10.1007/s00281-007-0072-5

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The remission of rheumatoid arthritis during pregnancy

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