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01-05-2020 | Magnetic Resonance Imaging | Special Section: Pancreatitis

Differentiation of focal autoimmune pancreatitis from pancreatic ductal adenocarcinoma

Authors: Camila Lopes Vendrami, Joon Soo Shin, Nancy A. Hammond, Kunal Kothari, Pardeep K. Mittal, Frank H. Miller

Published in: Abdominal Radiology | Issue 5/2020

Abstract

Autoimmune pancreatitis (AIP) is an inflammatory process of the pancreas that occurs most commonly in elderly males and clinically can mimic pancreatic adenocarcinoma and present with jaundice, weight loss, and abdominal pain. Mass-forming lesions in the pancreas are seen in the focal form of AIP and both clinical and imaging findings can overlap those of pancreatic cancer. The accurate distinction of AIP from pancreatic cancer is of utmost importance as it means avoiding unnecessary surgery in AIP cases or inaccurate steroid treatment in patients with pancreatic cancer. Imaging concomitantly with serological examinations (IgG4 and Ca 19-9) plays an important role in the distinction between these entities. Characteristic extra-pancreatic manifestations as well as favorable good response to treatment with steroids are characteristic of AIP. This paper will review current diagnostic parameters useful in differentiating between focal AIP and pancreatic adenocarcinoma.

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Title: Differentiation of focal autoimmune pancreatitis from pancreatic ductal adenocarcinoma
Authors: Camila Lopes Vendrami
Joon Soo Shin
Nancy A. Hammond
Kunal Kothari
Pardeep K. Mittal
Frank H. Miller
Publication date: 01-05-2020
Publisher: Springer US
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Computed Tomography
Computed Tomography
Autoimmune Pancreatitis
Chronic Pancreatitis
Pancreatitis
Pancreatic Cancer
Pancreatic Cancer
Published in: Abdominal Radiology / Issue 5/2020
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-019-02210-0

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