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Pediatric Radiology
Published in: Pediatric Radiology 4/2019

01-04-2019 | Magnetic Resonance Imaging | Minisymposium: Quality and safety

Gadolinium-based contrast agents — review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients

Authors: Einat Blumfield, David W. Swenson, Ramesh S. Iyer, A. Luana Stanescu

Published in: Pediatric Radiology | Issue 4/2019

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Abstract

Gadolinium has been used as a base for contrast agents in MRI for the last three decades. Numerous studies over the last 4 years have reported increased signal intensity in deep brain nuclei in non-contrast MRI images following gadolinium-based contrast agent (GBCA) administration. Pathology studies performed on adults and children, and rodent necropsy studies have also shown gadolinium deposition in brain and other tissues after GBCA administration. The purpose of this review was to summarize and discuss the knowledge gained from these reports and the relevance for imaging pediatric patients.
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Metadata
Title
Gadolinium-based contrast agents — review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients
Authors
Einat Blumfield
David W. Swenson
Ramesh S. Iyer
A. Luana Stanescu
Publication date
01-04-2019
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 4/2019
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-018-4304-8

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