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Open Access 01-05-2020 | Urge Incontinence | Clinical Opinion

Posterior tibial nerve stimulation for overactive bladder—techniques and efficacy

Authors: Alka A. Bhide, Visha Tailor, Ruwan Fernando, Vik. Khullar, Giuseppe Alessandro Digesu

Published in: International Urogynecology Journal | Issue 5/2020

Abstract

The ideal treatment for overactive bladder is still elusive. In those where medication fails to improve symptoms options include invasive treatments such as botulinum toxin-A, sacral neural stimulation or posterior tibial nerve stimulation. Scientific professional society guidelines advise percutaneous posterior tibial nerve stimulation as a third line treatment option only after multi-disciplinary team review as well as failure of both conservative and pharmacological management. The aim of this article is to review all techniques for tibial nerve stimulation and their efficacy.

Bo K, Frawley HC, Haylen BT, et al. An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for the conservative and nonpharmacological management of female pelvic floor dysfunction. Int Urogynecol J. 2017;28(2):191–213. https://doi.org/10.1007/s00192-016-3123-4.CrossRefPubMed

Rachaneni S, Latthe P. Effectiveness of BTX-A and neuromodulation in treating OAB with or without detrusor overactivity: a systematic review. Int Urogynecol J. 2017;28(6):805–16. https://doi.org/10.1007/s00192-016-3225-z.CrossRefPubMed

Elmer-Lyon CG, Streit JA, Takacs EB, Ten Eyck PP, Bradley CS. Urinary tract infection and drug-resistant urinary tract infection after intradetrusor onabotulinumtoxinA injection versus sacral neuromodulation. Int Urogynecol J. 2019. https://doi.org/10.1007/s00192-019-04007-7.

Tran AM, Sand PK, Seitz MJ, Gafni-Kane A, Zhou Y, Botros SM. Does physician specialty affect persistence to pharmacotherapy among patients with overactive bladder syndrome? Int Urogynecol J. 2017;28(3):409–15. https://doi.org/10.1007/s00192-016-3118-1.CrossRefPubMed

Foust-Wright C, Wissig S, Stowell C, Olson E, Anderson A, Anger J, et al. Development of a core set of outcome measures for OAB treatment. Int Urogynecol J. 2017;28(12):1785–93. https://doi.org/10.1007/s00192-017-3481-6.CrossRefPubMedPubMedCentral

Gaziev G, Topazio L, Iacovelli V, Asimakopoulos A, Di Santo A, De Nunzio C, et al. Percutaneous tibial nerve stimulation (PTNS) efficacy in the treatment of lower urinary tract dysfunctions: a systematic review. BMC Urol. 2013;13:61.CrossRef

Ramirez-Garcia I, Blanco-Ratto L, Kauffman S, Carralero-Martinez A, Sanchez E. Efficacy of transcutaneous stimulation of the posterior tibial nerve compared to percutaneous stimulation in idiopathic overactive bladder syndrome: randomized control trial. Neuro Urol. 2019;38:261–8.CrossRef

Van Der Pal F, Van Balken MR, Heesakkers JPFA, Debruyne FMJ, Bemelmans BLH. Implant-driven tibial nerve stimulation in the treatment of refractory overactive bladder syndrome: 12-month follow-up. Neuromodulation. 2006;9(2):163–71.CrossRef

Janssen DA, Farag F, Heesakkers J. Urgent-SQ implant in treatment of overactive bladder syndrome: 9-year follow-up study. Neurourol Urodyn Jun. 2013;32(5):472–5.CrossRef

10.

Breda HMK, Van Martens FMJ, Tromp J, Heesakkers J (2017). New technology and techniques a new implanted posterior Tibial nerve stimulator for the treatment of overactive bladder syndrome: 3-month results of a novel therapy at a single center. J Urol 198(1):205–210. Available from: doi:https://doi.org/10.1016/j.juro.2017.01.078.

11.

MacDiarmid S, Staskin DR, Lucente V, Kaaki B, Sharon English P, Gilling, et al. Feasibility of a fully implanted, nickel sized and shaped Tibial nerve stimulator for the treatment of overactive bladder syndrome with urgency incontinence. J Urol. 2019;201(5):967–72.CrossRef

12.

Karademir K, Baykal K, Sen B, Senkul T, Iseri C. A peripheric neuromodulation technique for curing detrusor overactivity: Stoller afferent neurostimulation. Scand J Urol Nephrol. 2009;39(3):230–3.CrossRef

13.

Sancaktar M, Ceyhan ST, Akyol I, Muhcu M, Ercan CM, Atay V. (2010) The outcome of adding peripheral neuromodulation (stoller afferent neuro- stimulation) to anti-muscarinic therapy in women with severe overactive bladder. Gynecol Endocrinol. Oct;26(10):729-732.

14.

Vecchioli-scaldazza C, Morosetti C. Effectiveness and durability of solifenacin versus percutaneous tibial nerve stimulation versus their combination for the treatment of women with overactive bladder syndrome: a randomized controlled study with a follow-up of ten months. Int Braz J Urol. 2018;44(1):102–8.CrossRef

15.

Finazzi-agrò E, Petta F, Sciobica F, Pasqualetti P, Musco S, Bove P. (2010) Percutaneous Tibial nerve stimulation effects on detrusor Overactivity incontinence are not due to a placebo effect: a randomized, double-blind, placebo controlled trial. J Urology 184(5):2001–2006. Available from doi:https://doi.org/10.1016/j.juro.2010.06.113.

16.

Peters KM, Carrico DJ, Perez-marrero RA, Khan AU, Wooldridge LS, Davis GL, et al. (2010) Randomized trial of percutaneous Tibial nerve stimulation versus sham efficacy in the treatment of overactive bladder syndrome: results from the SUmiT trial. J Urol 183(4):1438–1443. Available from: doi:https://doi.org/10.1016/j.juro.2009.12.036.

17.

Ugurlucan FG, Onal M, Aslan E, Ayyildiz Erkan H, Kizilkaya Beji N, Yalcin O. Comparison of the effects of electrical stimulation and posterior tibial nerve stimulation in the treatment of overactive bladder syndrome. Gynecol Obstet Investig. 2013;75(1):46–52.CrossRef

18.

Scaldazza CV, Morosetti C, Giampieretti R, Lorenzetti R. Percutaneous tibial nerve stimulation versus electrical stimulation with pelvic floor muscle training for overactive bladder syndrome in women: results of a randomized controlled study. Int Braz J Urol. 2017;43(1):121–6.CrossRef

19.

Yoong W, Ridout AE, Damodaram M, Dadswell R. Tibial nerve stimulation for intractable detrusor 6-week protocol. BJU Int. 2010;106(11):1673–6.CrossRef

20.

Van Der Pal F, Van Balken MR, Heesakkers JPFA, Debruyne FMJ, Bemelmans BLH. Percutaneous tibial nerve stimulation in the treatment of refractory overactive bladder syndrome: is maintenance treatment necessary? BJU Int. 2006;97:547–50.CrossRef

21.

Iyer S, Laus K, Rugino A, Botros C, Lozo S, Botros SM, et al. Subjective and objective responses to PTNS and predictors for success: a retrospective cohort study of percutaneous tibial nerve stimulation for overactive bladder. Int Urogynecol J. 2018. https://doi.org/10.1007/s00192-018-3822-0.

22.

Rostaminia G, Chang C, Pincus JB, Sand PK, Goldberg RP. Predictors of successful percutaneous tibial nerve stimulation (PTNS) in the treatment of overactive bladder syndrome. Int Urogynecol J. 2018. https://doi.org/10.1007/s00192-018-3834-9.

23.

Verghese TS, Middleton LJ, Daniels JP, Deeks JJ, Latthe PM. The impact of urodynamics on treatment and outcomes in women with an overactive bladder: a longitudinal prospective follow-up study. Int Urogynecol J. 2018;29(4):513–9. https://doi.org/10.1007/s00192-017-3414-4.CrossRefPubMed

24.

Macdiarmid SA, Peters KM, Shobeiri SA, Wooldridge LS, Rovner ES, Leong C, et al. (2010) Long-term durability of percutaneous Tibial nerve stimulation for the treatment of overactive bladder. J Urology 183(1):234–240. Available from: doi:https://doi.org/10.1016/j.juro.2009.08.160.

25.

Peters KM, Carrico DJ, Wooldridge LS, Miller CJ, Macdiarmid SA (2013). Percutaneous Tibial nerve stimulation for the long-term treatment of overactive bladder: 3-year results of the STEP study. J Urology 189(6):2194–2201. Available from: doi:https://doi.org/10.1016/j.juro.2012.11.175.

26.

Arrabal-polo MA, Palao-yago F, Campon-pacheco I, Martinez-sanchez M, Zuluaga-gomez A, Arrabal-martin M. Clinical efficacy in the treatment of overactive bladder refractory to anticholinergics by posterior tibial nerve stimulation. Korean J Urol. 2012;53(7):483–6.CrossRef

27.

Río-gonzalez S Del, Aragon IM, Castillo E, Milla-españa F, Galacho A, Machuca J, et al. (2017) Percutaneous tibial nerve stimulation therapy for overactive bladder syndrome: clinical effectiveness, urodynamic, and durability evaluation. Urology 108:52–58. Available from: doi:https://doi.org/10.1016/j.urology.2017.04.059.

28.

Zecca C, Panicari L, Disanto G, Maino P, Singh A, Digesu GA, et al. Posterior tibial nerve stimulation in the management of lower urinary tract symptoms in patients with multiple sclerosis. Int Urogynecol J. 2016;27(4):521–7.CrossRef

29.

Kabay SC, Kabay S, Mestan E, Cetiner M, Ayas S, Sevim M, et al. Long term sustained therapeutic effects of percutaneous posterior tibial nerve stimulation treatment of neurogenic overactive bladder in multiple sclerosis patients: 12-months results. Neurourol Urodyn. 2017;36(1):104–10.CrossRef

30.

Kershaw V, Khunda A, McCormick C, Ballard P. The effect of percutaneous tibial nerve stimulation (PTNS) on sexual function: a systematic review and meta-analysis. Int Urogynecol J. 2019. https://doi.org/10.1007/s00192-019-04027-3.

31.

Souto SC, Reis LO. Prospective and randomized comparison of electrical stimulation of the posterior tibial nerve versus oxybutynin versus their combination for treatment of women with overactive bladder syndrome. World J Urol. 2014;32(1):179–84.CrossRef

32.

Manríquez V, Guzmán R, Naser M, Aguilera A, Narvaez S, Castro A, et al. Transcutaneous posterior tibial nerve stimulation versus extended release oxybutynin in overactive bladder patients. A prospective randomized trial. Eur J Obstet Gynecol Reprod Biol. 2016;196:6–10.CrossRef

33.

Furtado-Albanezi D, Jürgensen SP, Avila MA, Correia GN, Driusso P. Effects of two nonpharmacological treatments on the sleep quality of women with nocturia: a randomized controlled clinical trial. Int Urogynecol J. 2019;30(2):279–86.CrossRef

34.

van Breda HMK, Martens FMJ, Tromp J, Heesakkers JPFA. A new implanted posterior tibial nerve stimulator for the treatment of overactive bladder syndrome: 3-month results of a novel therapy at a single center. J Urol. 2017;198(1):205–10.CrossRef

35.

Heesakkers JPFA, Van Kerrebroeck P. A novel leadless, miniature implantable tibial nerve neuromodulation system for the management of overactive bladder complaints. Neurourol Urodyn. 2018;37(3):1060–7.CrossRef

36.

Rohloff M, Peifer G, Thompson JH. Patient navigation for overactive bladder improves access to care. Int Urogynecol J. 2019, 2019. https://doi.org/10.1007/s00192-019-04085-7.

Title: Posterior tibial nerve stimulation for overactive bladder—techniques and efficacy
Authors: Alka A. Bhide
Visha Tailor
Ruwan Fernando
Vik. Khullar
Giuseppe Alessandro Digesu
Publication date: 01-05-2020
Publisher: Springer International Publishing
Keywords: Urge Incontinence
Overactive Bladder
Nerve Stimulation
Published in: International Urogynecology Journal / Issue 5/2020
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-019-04186-3

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Posterior tibial nerve stimulation for overactive bladder—techniques and efficacy

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