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International Urogynecology Journal
Published in: International Urogynecology Journal 8/2019

01-08-2019 | Original Article

Subjective and objective responses to PTNS and predictors for success: a retrospective cohort study of percutaneous tibial nerve stimulation for overactive bladder

Authors: Shilpa Iyer, Katharina Laus, Angela Rugino, Carolyn Botros, Svjetlana Lozo, Sylvia M. Botros, Roger Goldberg, Janet Tomezsko, Adam Gafni-Kane, Kristen Wroblewski, Peter Sand

Published in: International Urogynecology Journal | Issue 8/2019

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Abstract

Introduction and hypothesis

We investigated the objective improvements in overactive bladder (OAB) symptoms in patients undergoing percutaneous tibial nerve stimulation (PTNS) and predictive factors of patient satisfaction.

Methods

In this single-center retrospective cohort study at a tertiary urogynecology center, we identified all female patients who underwent PTNS therapy from 1 October 2007 – 1 January 2016 and followed them from their initial visit through medication therapy and PTNS treatments. Patients who tried at least one medication prior to starting PTNS therapy and completed at least one PTNS visit were included. Baseline demographic data, urinary data, and details of medication and PTNS therapy sessions were collected from records through chart review. Paired or two-sample t-tests were used to compare changes over time or groups. Bivariate and multivariable logistic regression were performed.

Results

Two hundred thirteen patients underwent PTNS therapy and 183 patients met the criteria. Overall patients were able to decrease voiding frequency by 1 h, decrease nocturia episodes by 0.8, and decrease urge incontinence episodes with PTNS therapy by ten episodes per week (p = 0.02). Patients who continued OAB medications did not have additional improvements compared with patients who did not continue OAB medications during PTNS. Overall, 25.4% (43/169) patients reported ≥ 75% improvement during PTNS therapy, and 61.5% (104/169) reported ≥ 50% improvement. When evaluating predictive factors of ≥ 50% overall improvement, the number of PTNS sessions increased odds of subjective success (OR = 1.8, p = 0.004). Other factors were not significant predictors of subjective PTNS success.

Conclusions

PTNS can provide both objective and subjective improvements for patients who do not respond to OAB medication therapy.
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Metadata
Title
Subjective and objective responses to PTNS and predictors for success: a retrospective cohort study of percutaneous tibial nerve stimulation for overactive bladder
Authors
Shilpa Iyer
Katharina Laus
Angela Rugino
Carolyn Botros
Svjetlana Lozo
Sylvia M. Botros
Roger Goldberg
Janet Tomezsko
Adam Gafni-Kane
Kristen Wroblewski
Peter Sand
Publication date
01-08-2019
Publisher
Springer International Publishing
Published in
International Urogynecology Journal / Issue 8/2019
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-018-3822-0

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