Top

Published in:

01-03-2006 | Year in Review 2005

Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury

Authors: Peter Andrews, Elie Azoulay, Massimo Antonelli, Laurent Brochard, Christian Brun-Buisson, Geoffrey Dobb, Jean-Yves Fagon, Herwig Gerlach, Johan Groeneveld, Jordi Mancebo, Philipp Metnitz, Stefano Nava, Jerome Pugin, Michael Pinsky, Peter Radermacher, Christian Richard, Robert Tasker

Published in: Intensive Care Medicine | Issue 3/2006

Excerpt

Because of their poor prognosis, patients with advanced haematological malignancies may be denied ICU admission. In a prospective cohort study of 172 patients with haematological malignancy admitted to a single ICU over a 4-year period, Benoit et al. [1] examined hospital and 6-month mortality after stratification on whether an infection was present, suspected or absent on ICU admission. After adjustment for the severity of critical and underlying haematological illness and the duration of hospitalisation before admission, documented ([odds ratio] OR 0.20; p = 0.006) and clinically suspected bacterial infection (OR 0.18; p = 0.002) were found associated with a more favourable outcome than nonbacterial complications leading to admission. The authors conclude that since the former have a better outcome, such patients should receive full supportive care for an adequate period of time. …

Benoit DD, Depuydt PO, Peleman RA, Offner FC, Vandewoude KH, Vogelaers DP, Blot SI, Noens LA, Colardyn FA, Decruyenaere JM (2005) Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome. Intensive Care Med 31:934–942PubMedCrossRef

Brivet FG, Ducuing S, Jacobs F, Chary I, Pompier R, Prat D, Grigoriu BD, Nordmann P (2005) Accuracy of clinical presentation for differentiating bacterial from viral meningitis in adults: a multivariate approach. Intensive Care Med 31:1654--1660PubMedCrossRef

Zimmerli W (2005) How to differentiate bacterial from viral meningitis. Intensive Care Med 31:1608--1610PubMedCrossRef

Laupland KB, Zygun DA, Doig CJ, Bagshaw SM, Svenson LW, Fick GH (2005) One-year mortality of bloodstream infection-associated sepsis and septic shock among patients presenting to a regional critical care system. Intensive Care Med 31:213–219PubMedCrossRef

Quartin AA, Schein RM, Kett DH, Peduzzi PN (1997) Magnitude and duration of the effect of sepsis on survival. Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group. JAMA 277:1058–1063PubMedCrossRef

Dodek P (2005) Surviving sepsis-but for how long? Intensive Care Med 31:171–173PubMedCrossRef

Tsai MS, Chiang WC, Lee CC, Hsieh CC, Ko PC, Hsu CY, Su CP, Chen SY, Chang WT, Yuan A, Ma MH, Chen SC, Chen WJ (2005) Infections in the survivors of out-of-hospital cardiac arrest in the first 7 days. Intensive Care Med 31:621–626PubMedCrossRef

Tanguy M, Seguin P, Laviolle B, Desbordes L, Malledant Y (2005) Hub qualitative blood culture is useful for diagnosis of catheter-related infections in critically ill patients. Intensive Care Med 31:645--648PubMedCrossRef

Harb A, Estphan G, Nitenberg G, Chachaty E, Raynard B, Blot F (2005) Indwelling time and risk of infection of dialysis catheters in critically ill cancer patients. Intensive Care Med 31:812–817PubMedCrossRef

10.

Charles PE, Dalle F, Aube H, Doise JM, Quenot JP, Aho LS, Chavanet P, Blettery B (2005) Candida spp. colonization significance in critically ill medical patients: a prospective study. Intensive Care Med 31:393–400PubMedCrossRef

11.

Normand S, Francois B, Darde ML, Bouteille B, Bonnivard M, Preux PM, Gastinne H, Vignon P (2005) Oral nystatin prophylaxis of Candida spp. colonization in ventilated critically ill patients. Intensive Care Med 31:1508–1513PubMedCrossRef

12.

Eggimann P, Calandra T, Fluckiger U, Bille J, Garbino J, Glauser MP, Marchetti O, Ruef C, Tauber M, Pittet D (2005) Invasive candidiasis: comparison of management choices by infectious disease and critical care specialists. Intensive Care Med 31:1514–1521PubMedCrossRef

13.

Eggimann P, Wolff M, Garbino J (2005) Oral nystatin as antifungal prophylaxis in critically ill patients: an old SDD tool to be renewed? Intensive Care Med 31:1466–1468PubMedCrossRef

14.

Lucet JC, Paoletti X, Lolom I, Paugam-Burtz C, Trouillet JL, Timsit JF, Deblangy C, Andremont A, Regnier B (2005) Successful long-term program for controlling methicillin-resistant Staphylococcus aureus in intensive care units. Intensive Care Med 31:1051–1057PubMedCrossRef

15.

Pittet D, Hugonnet S, Harbarth S, Mourouga P, Sauvan V, Touveneau S, Perneger TV (2000) Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme. Lancet 356:1307–1312PubMedCrossRef

16.

Trouillet JL, Chastre J, Vuagnat A, Joly-Guillou ML, Combaux D, Dombret MC, Gibert C (1998) Ventilator-associated pneumonia caused by potentially drug-resistant bacteria. Am J Respir Crit Care Med 157:531–539PubMed

17.

Leone M, Delliaux S, Bourgoin A, Albanese J, Garnier F, Boyadjiev I, Antonini F, Martin C (2005) Risk factors for late-onset ventilator-associated pneumonia in trauma patients receiving selective digestive decontamination. Intensive Care Med 31:64–70PubMedCrossRef

18.

Garnacho-Montero J, Ortiz-Leyba C, Fernandez-Hinojosa E, Aldabo-Pallas T, Cayuela A, Marquez-Vacaro JA, Garcia-Curiel A, Jimenez-Jimenez FJ (2005) Acinetobacter baumannii ventilator-associated pneumonia: epidemiological and clinical findings. Intensive Care Med 31:649–655PubMedCrossRef

19.

Reina R, Estenssoro E, Saenz G, Canales HS, Gonzalvo R, Vidal G, Martins G, Das Neves A, Santander O, Ramos C (2005) Safety and efficacy of colistin in Acinetobacter and Pseudomonas infections: a prospective cohort study. Intensive Care Med 31:1058–1065PubMedCrossRef

20.

Garnacho-Montero J, Ortiz-Leyba C, Jimenez-Jimenez FJ, Barrero-Almodovar E, Garcia-Garmendia JL, Bernabeu-Witell M, Gallego-Lara S, Madrazo-Osuna J (2003) Treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia with intravenous colistin: a comparison with imipenem-susceptible VAP. Clin Infect Dis 36:1111–1118PubMedCrossRef

21.

Acquarolo A, Urli T, Perone G, Giannotti C, Candiani A, Latronico N (2005) Antibiotic prophylaxis of early onset pneumonia in critically ill comatose patients. A randomized study. Intensive Care Med 31:510–516PubMedCrossRef

22.

Ibrahim EH, Ward S, Sherman G, Kollef MH (2000) A comparative analysis of patients with early-onset vs late-onset nosocomial pneumonia in the ICU setting. Chest 117:1434–1442PubMedCrossRef

23.

Giantsou E, Liratzopoulos N, Efraimidou E, Panopoulou M, Alepopoulou E, Kartali-Ktenidou S, Minopoulos GI, Zakynthinos S, Manolas KI (2005) Both early-onset and late-onset ventilator-associated pneumonia are caused mainly by potentially multiresistant bacteria. Intensive Care Med 31:1488–1494PubMedCrossRef

24.

Chastre J (2005) Antibiotic prescribing for ventilator-associated pneumonia: get it right from the beginning but be able to rapidly deescalate. Intensive Care Med 31:1463–1465PubMedCrossRef

25.

Determann RM, Millo JL, Gibot S, Korevaar JC, Vroom MB, van der Poll T, Garrard CS, Schultz MJ (2005) Serial changes in soluble triggering receptor expressed on myeloid cells in the lung during development of ventilator-associated pneumonia. Intensive Care Med 31:1495–1500PubMedCrossRef

26.

Carlet J, Thijs LG, Antonelli M, Cassell J, Cox P, Hill N, Hinds C, Pimentel JM, Reinhart K, Thompson BT (2004) Challenges in end-of-life care in the ICU. Statement of the Fifth International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. Intensive Care Med 30:770–784PubMedCrossRef

27.

Yazigi A, Riachi M, Dabbar G (2005) Withholding and withdrawal of life-sustaining treatment in a Lebanese intensive care unit: a prospective observational study. Intensive Care Med 31:562–567PubMedCrossRef

28.

Pochard F, Abroug F (2005) End-of-life decisions in ICU and cultural specificities. Intensive Care Med 31:506–507PubMedCrossRef

29.

Ho KM, English S, Bell J (2005) The involvement of intensive care nurses in end-of-life decisions: a nationwide survey. Intensive Care Med 31:668–673PubMedCrossRef

30.

Wunsch H, Harrison DA, Harvey S, Rowan K (2005) End-of-life decisions: a cohort study of the withdrawal of all active treatment in intensive care units in the United Kingdom. Intensive Care Med 31:823–831PubMedCrossRef

31.

Cohen S, Sprung C, Sjokvist P, Lippert A, Ricou B, Baras M, Hovilehto S, Maia P, Phelan D, Reinhart K, Werdan K, Bulow HH, Woodcock T (2005) Communication of end-of-life decisions in European intensive care units. Intensive Care Med 31:1215–1221PubMedCrossRef

32.

Sluiter JK, Bos AP, Tol D, Calff M, Krijnen M, Frings-Dresen MH (2005) Is staff well-being and communication enhanced by multidisciplinary work shift evaluations? Intensive Care Med 31:1409–1414PubMedCrossRef

33.

Young E, Eddleston J, Ingleby S, Streets J, McJanet L, Wang M, Glover L (2005) Returning home after intensive care: a comparison of symptoms of anxiety and depression in ICU and elective cardiac surgery patients and their relatives. Intensive Care Med 31:86–91PubMedCrossRef

34.

Crowther MA, Cook DJ, Griffith LE, Meade M, Hanna S, Rabbat C, Bates SM, Geerts W, Johnston M, Guyatt G (2005) Neither baseline tests of molecular hypercoagulability nor D-dimer levels predict deep venous thrombosis in critically ill medical-surgical patients. Intensive Care Med 31:48–55PubMedCrossRef

35.

Le Gal G, Bounameaux H (2005) D-dimer for the diagnosis of pulmonary embolism: a call for sticking to evidence. Intensive Care Med 31:1–2PubMedCrossRef

36.

Sivula M, Tallgren M, Pettila V (2005) Modified score for disseminated intravascular coagulation in the critically ill. Intensive Care Med 31:1209–1214PubMedCrossRef

37.

Pene F, Vigneau C, Auburtin M, Moreau D, Zahar JR, Coste J, Heshmati F, Mira JP (2005) Outcome of severe adult thrombotic microangiopathies in the intensive care unit. Intensive Care Med 31:71–78PubMedCrossRef

38.

Aegerter P, Boumendil A, Retbi A, Minvielle E, Dervaux B, Guidet B (2005) SAPS II revisited. Intensive Care Med 31:416–423PubMedCrossRef

39.

Metnitz PG, Moreno RP, Almeida E, Jordan B, Bauer P, Campos RA, Iapichino G, Edbrooke D, Capuzzo M, Le Gall JR (2005) SAPS 3-From evaluation of the patient to evaluation of the intensive care unit. Part 1: Objectives, methods and cohort description. Intensive Care Med 31:1336–1344PubMedCrossRef

40.

Moreno RP, Metnitz PG, Almeida E, Jordan B, Bauer P, Campos RA, Iapichino G, Edbrooke D, Capuzzo M, Le Gall JR (2005) SAPS 3-From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med 31:1345–1355PubMedCrossRef

41.

Suter PM (2005) Some ICUs save more lives than others: we need to know why! Intensive Care Med 31:1301–1302PubMedCrossRef

42.

Afessa B, Keegan MT, Gajic O, Hubmayr RD, Peters SG (2005) The influence of missing components of the Acute Physiology Score of APACHE III on the measurement of ICU performance. Intensive Care Med 31:1537–1543PubMedCrossRef

43.

Soares M, Salluh JI, Ferreira CG, Luiz RR, Spector N, Rocco JR (2005) Impact of two different comorbidity measures on the 6-month mortality of critically ill cancer patients. Intensive Care Med 31:408–415PubMedCrossRef

44.

Kajdacsy-Balla Amaral AC, Andrade FM, Moreno R, Artigas A, Cantraine F, Vincent JL (2005) Use of the sequential organ failure assessment score as a severity score. Intensive Care Med 31:243–249CrossRef

45.

Cabré L, Mancebo J, Solsona JF, Saura P, Gich I, Blanch L, Carrasco G, Martin MC (2005) Multicenter study of the multiple organ dysfunction syndrome in intensive care units: the usefulness of Sequential Organ Failure Assessment scores in decision making. Intensive Care Med 31:927–933PubMedCrossRef

46.

du Cheyron D, Bouchet B, Parienti JJ, Ramakers M, Charbonneau P (2005) The attributable mortality of acute renal failure in critically ill patients with liver cirrhosis. Intensive Care Med 31:1693–1699CrossRef

47.

Munnur U, Karnad DR, Bandi VD, Lapsia V, Suresh MS, Ramshesh P, Gardner MA, Longmire S, Guntupalli KK (2005) Critically ill obstetric patients in an American and an Indian public hospital: comparison of case-mix, organ dysfunction, intensive care requirements, and outcomes. Intensive Care Med 31:1087–1094PubMedCrossRef

48.

Azoulay E, Alberti C, Legendre I, Buisson CB, Le Gall JR (2005) Post-ICU mortality in critically ill infected patients: an international study. Intensive Care Med 31:56–63PubMedCrossRef

49.

Heidegger CP, Treggiari MM, Romand JA (2005) A nationwide survey of intensive care unit discharge practices. Intensive Care Med 31:1676--1682PubMedCrossRef

50.

Barrett H, Bion JF (2005) An international survey of training in adult intensive care medicine. Intensive Care Med 31:553–561PubMedCrossRef

51.

Lescot T, Bonnet MP, Zouaoui A, Muller JC, Fetita C, Coriat P, Puybasset L (2005) A quantitative computed tomography assessment of brain weight, volume, and specific gravity in severe head trauma. Intensive Care Med 31:1042–1050PubMedCrossRef

52.

Stocchetti N (2005) Does the brain become heavier or lighter after trauma? The long story of brain water content and its direct or indirect measurement. Intensive Care Med 31:1009–1011PubMedCrossRef

53.

Hukkelhoven CW, Steyerberg EW, Habbema JD, Maas AI (2005) Admission of patients with severe and moderate traumatic brain injury to specialized ICU facilities: a search for triage criteria. Intensive Care Med 31:799–806PubMedCrossRef

54.

Patel HC, Bouamra O, Woodford M, King AT, Yates DW, Lecky FE (2005) Trends in head injury outcome from 1989 to 2003 and the effect of neurosurgical care: an observational study. Lancet 366:1538–1544PubMedCrossRef

55.

Jaffres P, Brun J, Declety P, Bosson JL, Fauvage B, Schleiermacher A, Kaddour A, Anglade D, Jacquot C, Payen JF (2005) Transcranial Doppler to detect on admission patients at risk for neurological deterioration following mild and moderate brain trauma. Intensive Care Med 31:785–790PubMedCrossRef

56.

Doi M, Morita K, Mantzaridis H, Sato S, Kenny GN (2005) Prediction of responses to various stimuli during sedation: a comparison of three EEG variables. Intensive Care Med 31:41–47PubMedCrossRef

57.

Walsh TS, Ramsay P, Kinnunen R (2004) Monitoring sedation in the intensive care unit: can “black boxes” help us? Intensive Care Med 30:1511–1513PubMedCrossRef

58.

Mascia L, Grasso S, Fiore T, Bruno F, Berardino M, Ducati A (2005) Cerebro-pulmonary interactions during the application of low levels of positive end-expiratory pressure. Intensive Care Med 31:373–379PubMedCrossRef

59.

Andrews PJ (2005) Pressure, flow and Occam's Razor: a matter of “steal”? Intensive Care Med 31:323–324PubMedCrossRef

60.

Martinez-Lucas P, Moreno-Cuesta J, Garcia-Olmo DC, Sanchez-Sanchez F, Escribano-Martinez J, del Pozo AC, Lizan-Garcia M, Garcia-Olmo D (2005) Relationship between the Arg72Pro polymorphism of p53 and outcome for patients with traumatic brain injury. Intensive Care Med 31:1168–1173PubMedCrossRef

61.

Nakos G, Tziakou E, Maneta-Peyret L, Nassis C, Lekka ME (2005) Anti-phospholipid antibodies in serum from patients with Guillain-Barre syndrome. Intensive Care Med 31:1401–1408PubMedCrossRef

62.

Laplace C, Huet O, Vicaut E, Ract C, Martin L, Benhamou D, Duranteau J (2005) Endothelial oxidative stress induced by serum from patients with severe trauma hemorrhage. Intensive Care Med 31:1174–1180PubMedCrossRef

63.

Minambres E, Lopez-Escribano H, Ballesteros MA, Pena M, Lopez-Hoyos M (2005) Apoptosis of Jurkat cells induced by serum of patients with acute severe brain injury. Intensive Care Med 31:791–798PubMedCrossRef

Title: Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury
Authors: Peter Andrews
Elie Azoulay
Massimo Antonelli
Laurent Brochard
Christian Brun-Buisson
Geoffrey Dobb
Jean-Yves Fagon
Herwig Gerlach
Johan Groeneveld
Jordi Mancebo
Philipp Metnitz
Stefano Nava
Jerome Pugin
Michael Pinsky
Peter Radermacher
Christian Richard
Robert Tasker
Publication date: 01-03-2006
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 3/2006
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-005-0060-y

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury

Excerpt

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 3/2006

Melatonin: possible implications for the postoperative and critically ill patient

Dramatic beneficial effects of sildenafil in recurrent massive pulmonary embolism

Weight-adjusted resting energy expenditure is not constant in critically ill patients

Organ dysfunction during sepsis

Authors' reply to the comment by Dr. Cakar et al.

An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence in Acutely ill Patients (SOAP) study