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Intensive Care Medicine
Published in: Intensive Care Medicine 10/2005

Open Access 01-10-2005 | Original

SAPS 3—From evaluation of the patient to evaluation of the intensive care unit. Part 1: Objectives, methods and cohort description

Authors: Philipp G. H. Metnitz, Rui P. Moreno, Eduardo Almeida, Barbara Jordan, Peter Bauer, Ricardo Abizanda Campos, Gaetano Iapichino, David Edbrooke, Maurizia Capuzzo, Jean-Roger Le Gall, on behalf of the SAPS 3 Investigators

Published in: Intensive Care Medicine | Issue 10/2005

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Abstract

Objective

Risk adjustment systems now in use were developed more than a decade ago and lack prognostic performance. Objective of the SAPS 3 study was to collect data about risk factors and outcomes in a heterogeneous cohort of intensive care unit (ICU) patients, in order to develop a new, improved model for risk adjustment.

Design

Prospective multicentre, multinational cohort study.

Patients and setting

A total of 19,577 patients consecutively admitted to 307 ICUs from 14 October to 15 December 2002.

Measurements and results

Data were collected at ICU admission, on days 1, 2 and 3, and the last day of the ICU stay. Data included sociodemographics, chronic conditions, diagnostic information, physiological derangement at ICU admission, number and severity of organ dysfunctions, length of ICU and hospital stay, and vital status at ICU and hospital discharge. Data reliability was tested with use of kappa statistics and intraclass-correlation coefficients, which were >0.85 for the majority of variables. Completeness of the data was also satisfactory, with 1 [0–3] SAPS II parameter missing per patient. Prognostic performance of the SAPS II was poor, with significant differences between observed and expected mortality rates for the overall cohort and four (of seven) defined regions, and poor calibration for most tested subgroups.

Conclusions

The SAPS 3 study was able to provide a high-quality multinational database, reflecting heterogeneity of current ICU case-mix and typology. The poor performance of SAPS II in this cohort underscores the need for development of a new risk adjustment system for critically ill patients.
Appendix
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Metadata
Title
SAPS 3—From evaluation of the patient to evaluation of the intensive care unit. Part 1: Objectives, methods and cohort description
Authors
Philipp G. H. Metnitz
Rui P. Moreno
Eduardo Almeida
Barbara Jordan
Peter Bauer
Ricardo Abizanda Campos
Gaetano Iapichino
David Edbrooke
Maurizia Capuzzo
Jean-Roger Le Gall
on behalf of the SAPS 3 Investigators
Publication date
01-10-2005
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 10/2005
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2762-6

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