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Insights into Imaging

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Open Access 01-10-2017 | Review

The value of advanced MRI techniques in the assessment of cervical cancer: a review

Authors: Evelyn Dappa, Tania Elger, Annette Hasenburg, Christoph Düber, Marco J. Battista, Andreas M. Hötker

Published in: Insights into Imaging | Issue 5/2017

Abstract

Objectives

To assess the value of new magnetic resonance imaging (MRI) techniques in cervical cancer.

Methods

We searched PubMed and MEDLINE and reviewed articles published from 1990 to 2016 to identify studies that used MRI techniques, such as diffusion weighted imaging (DWI), intravoxel incoherent motion (IVIM) and dynamic contrast enhancement (DCE) MRI, to assess parametric invasion, to detect lymph node metastases, tumour subtype and grading, and to detect and predict tumour recurrence.

Results

Seventy-nine studies were included. The additional use of DWI improved the accuracy and sensitivity of the evaluation of parametrial extension. Most studies reported improved detection of nodal metastases. Functional MRI techniques have the potential to assess tumour subtypes and tumour grade differentiation, and they showed additional value in detecting and predicting treatment response. Limitations included a lack of technical standardisation, which limits reproducibility.

Conclusions

New advanced MRI techniques allow improved analysis of tumour biology and the tumour microenvironment. They can improve TNM staging and show promise for tumour classification and for assessing the risk of tumour recurrence. They may be helpful for developing optimised and personalised therapy for patients with cervical cancer.

Teaching points

• Conventional MRI plays a key role in the evaluation of cervical cancer.

• DWI improves tumour delineation and detection of nodal metastases in cervical cancer.

• Advanced MRI techniques show promise regarding histological grading and subtype differentiation.

• Tumour ADC is a potential biomarker for response to treatment.

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Title: The value of advanced MRI techniques in the assessment of cervical cancer: a review
Authors: Evelyn Dappa
Tania Elger
Annette Hasenburg
Christoph Düber
Marco J. Battista
Andreas M. Hötker
Publication date: 01-10-2017
Publisher: Springer Berlin Heidelberg
Published in: Insights into Imaging / Issue 5/2017
Electronic ISSN: 1869-4101
DOI: https://doi.org/10.1007/s13244-017-0567-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The value of advanced MRI techniques in the assessment of cervical cancer: a review

Abstract

Objectives

Methods

Results

Conclusions

Teaching points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Teaching points

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