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Published in: Current HIV/AIDS Reports 5/2021

01-10-2021 | Human Immunodeficiency Virus | Behavioral-Bio-Medical Interface (RJ DiClemente and JL Brown, Section Editors)

A Review of Interventions to Enhance HIV Medication Adherence

Authors: Laura B. Whiteley, Elizabeth M. Olsen, Kayla K. Haubrick, Enyonam Odoom, Nicholas Tarantino, Larry K. Brown

Published in: Current HIV/AIDS Reports | Issue 5/2021

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Abstract

Purpose of Review

Adherence to antiretroviral treatment (ART) is crucial for the successful treatment of HIV. Unfortunately, it is estimated that 45% of persons living with HIV (PLWH) have poor adherence to ART. To provide health care professionals and PLWH with effective tools for supporting adherence, researchers have investigated the effectiveness of psychosocial interventions to enhance adherence to ART. In this paper, interventional studies, systematic reviews, and meta-analyses that examine ART adherence interventions for PLWH are reviewed.

Recent Findings

There is great variability among interventions in terms of quality, sample, measures, and outcome characteristics. Despite a diverse and wide-ranging assortment of ART adherence interventions, consistent lessons have been learned. Interventions that focus on individual and interpersonal factors have been effective for improving ART adherence; however, the improvement in adherence tends to be short-lived. Additionally, interventions are most successful when tailored to those at risk for poor adherence. Finally, theory-based interventions are more likely to be effective than non-theory-based interventions.

Summary

A variety of individual-level psychological interventions have been shown to be effective in improving ART adherence in the short term. Digital and mobile interventions have the potential to improve dissemination and implementation of these evidence-based interventions and could be used to extend intervention effects. Future interventions that address issues of accessibility, inequality, structural and institutional barriers to ART adherence should also be tested and prioritized. Implementation science frameworks can be used to assess and address issues of accessibility and systematic barriers to care.
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Metadata
Title
A Review of Interventions to Enhance HIV Medication Adherence
Authors
Laura B. Whiteley
Elizabeth M. Olsen
Kayla K. Haubrick
Enyonam Odoom
Nicholas Tarantino
Larry K. Brown
Publication date
01-10-2021
Publisher
Springer US
Published in
Current HIV/AIDS Reports / Issue 5/2021
Print ISSN: 1548-3568
Electronic ISSN: 1548-3576
DOI
https://doi.org/10.1007/s11904-021-00568-9

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Prof. Anoop Chauhan
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