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01-10-2021 | Joint Pain | Multicenter Seminars: IBD (MUSE: IBD)

Clinical Challenge: From Ulcerative Colitis to Crohn’s Disease-Like Pouch Inflammation

Authors: Maia Kayal, Bhavana Bhagya Rao, Abhik Bhattacharya, Ryan Ungaro

Published in: Digestive Diseases and Sciences | Issue 10/2021

Excerpt

A 30-year-old man with a history of medically refractory ulcerative colitis (UC) and primary sclerosing cholangitis (PSC) for which he underwent three-stage total proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) was evaluated for complaints of frequency, urgency of bowel movements, abdominal pain, and joint pain. …

Kayal M, Plietz M, Rizvi A, et al. Inflammatory Pouch Conditions Are Common After Ileal Pouch Anal Anastomosis in Ulcerative Colitis Patients. Inflamm Bowel Dis 2019 2019/10/07. DOI: https://doi.org/10.1093/ibd/izz227.

Barnes EL, Kochar B, Jessup HR, et al. The Incidence and Definition of Crohn's Disease of the Pouch: A Systematic Review and Meta-analysis. Inflamm Bowel Dis 2019; 25: 1474–1480. 2019/01/31. DOI: https://doi.org/10.1093/ibd/izz005.

Lightner AL, Pemberton JH and Loftus EJ, Jr. Crohn's Disease of the Ileoanal Pouch. Inflamm Bowel Dis 2016; 22: 1502–1508. 2016/04/09. DOI: https://doi.org/10.1097/mib.0000000000000712.

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Truta B, Li DX, Mahadevan U, et al. Serologic markers associated with development of Crohn's disease after ileal pouch anal anastomosis for ulcerative colitis. Dig Dis Sci 2014; 59: 135–145. 2013/10/05. DOI: https://doi.org/10.1007/s10620-013-2866-8.

Coukos JA, Howard LA, Weinberg JM, et al. ASCA IgG and CBir antibodies are associated with the development of Crohn's disease and fistulae following ileal pouch-anal anastomosis. Dig Dis Sci 2012; 57: 1544–1553. 2012/02/09. DOI: https://doi.org/10.1007/s10620-012-2050-6.

Gregory M, Weaver KN, Hoversten P, et al. Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis 2019; 25: 1569–1576. 2019/02/28. DOI: https://doi.org/10.1093/ibd/izz030.

Huguet M, Pereira B, Goutte M, et al. Systematic Review With Meta-Analysis: Anti-TNF Therapy in Refractory Pouchitis and Crohn's Disease-Like Complications of the Pouch After Ileal Pouch-Anal Anastomosis Following Colectomy for Ulcerative Colitis. Inflamm Bowel Dis 2018; 24: 261–268. 2018/01/24. DOI: https://doi.org/10.1093/ibd/izx049.

Ollech JE, Rubin DT, Glick L, et al. Ustekinumab Is Effective for the Treatment of Chronic Antibiotic-Refractory Pouchitis. Dig Dis Sci 2019; 64: 3596–3601. 2019/06/13. DOI: https://doi.org/10.1007/s10620-019-05697-1.

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Kayal M, Lambin T, Plietz M, et al. Recycling of Precolectomy Anti-Tumor Necrosis Factor Agents in Chronic Pouch Inflammation Is Associated With Treatment Failure. Clin Gastroenterol Hepatol 2020 2020/07/16. DOI: https://doi.org/10.1016/j.cgh.2020.07.008.

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Mertz A, Nguyen NA, Katsanos KH, et al. Primary sclerosing cholangitis and inflammatory bowel disease comorbidity: an update of the evidence. Ann Gastroenterol 2019; 32: 124–133. 2019/03/07. DOI: https://doi.org/10.20524/aog.2019.0344.

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Barnes EL, Holubar SD and Herfarth HH. Systematic Review and Meta-Analysis of Outcomes after Ileal Pouch-Anal Anastomosis in Primary Sclerosing Cholangitis-Ulcerative Colitis. J Crohns Colitis 2021 2021/02/06. DOI: https://doi.org/10.1093/ecco-jcc/jjab025.

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Title: Clinical Challenge: From Ulcerative Colitis to Crohn’s Disease-Like Pouch Inflammation
Authors: Maia Kayal
Bhavana Bhagya Rao
Abhik Bhattacharya
Ryan Ungaro
Publication date: 01-10-2021
Publisher: Springer US
Keywords: Joint Pain
Ulcerative Colitis
Crohn's Disease
Ustekinumab
Primary Sclerosing Cholangitis
Pouchoscopy
Ileostomy
Erythema
Published in: Digestive Diseases and Sciences / Issue 10/2021
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI: https://doi.org/10.1007/s10620-021-07220-x

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