Published in:
01-08-2009 | Original Paper
Low-dose prospectively gated 256-slice coronary computed tomographic angiography
Authors:
Wm. Guy Weigold, Mark E. Olszewski, Matthew J. Walker
Published in:
The International Journal of Cardiovascular Imaging
|
Special Issue 2/2009
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Abstract
Since the introduction of 64-slice scanners, multidetector computed tomography (MDCT) has experienced a marked increase in adoption for the noninvasive assessment of coronary artery disease, although radiation dose concerns remain. The recent introduction of prospective coronary CT angiography (CCTA) has begun to address these concerns; however, its applicability with existing scanners remains limited to cohorts defined by heart rate, heart rate variability, and body mass index. This paper reviews prospective CCTA, the effect of heart rate and heart rate variability on image quality, and the physiologic basis for selection of optimal prospective imaging windows. We then discuss 256-slice technology and our first 4 months of clinical experience with 256-slice prospective CCTA. Our early clinical results indicate that high-quality, low-dose prospective coronary CTA may be applied to patients with higher heart rates, higher BMI, and with less sensitivity to heart rate variability using 256-slice MDCT.