Top

Published in:

01-12-2020 | Stroke | COVID-19

COVID-19 presenting with agraphia and conduction aphasia in a patient with left-hemisphere ischemic stroke

Authors: Konstantinos Priftis, Lorella Algeri, Stella Villella, Maria Simonetta Spada

Published in: Neurological Sciences | Issue 12/2020

Abstract

COVID-19 following infection by SARS-CoV-2 can affect the brain causing confusion, depression, and dementia-like signs. Nonetheless, the presence of more specific neuropsychological signs because of COVID-19 remains unexplored. We report on LA, a patient who was affected by a left-hemisphere ischemic stroke, probably because of SARS-CoV-2. The patient showed a highly specific neuropsychological profile characterized by severe agraphia and some signs of conduction aphasia. All other cognitive and sensorimotor functions remained intact. We sustain that specific neuropsychological signs can be observed in patients with COVID-19. Therefore, in-depth and comprehensive neuropsychological assessment should be included to better explore and qualify the neuropsychological consequences of COVID-19. This is a new challenge for diagnosis and rehabilitation, with important consequences for the involved neuropsychological services.

Paterson RW, Brown RL, Benjamin L, Nortley R, Wiethoff S, Bharucha T, Jayaseelan DL, Kumar G, Raftopoulos RE, Zambreanu L, Vivekanandam V, Khoo A, Geraldes R, Chinthapalli K, Boyd E, Tuzlali H, Price G, Christofi G, Morrow J et al (in press) The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings. Brain. https://doi.org/10.1093/brain/awaa240

Varatharaj A, Thomas N, Ellul MA, Davies NWS, Pollak TA, Tenorio EL, Sultan M, Easton A, Breen G, Zandi M, Coles JP, Manji H, Al-Shahi Salman R, Menon DK, Nicholson TR, Benjamin LA, Carson A, Smith C, Turner MR et al (in press) Neurological and neuropsychiatric complications of COVID-19 in 153 patients: A UK-wide surveillance study. Lancet Psychiatry. https://doi.org/10.1016/S2215-0366(20)30287-X

Helms J, Kremer S, Merdji H, Clere-Jehl R, Schenck M, Kummerlen C, Collange O, Boulay C, Fafi-Kremer S, Ohana M, Anheim M, Meziani F (2020) Neurologic features in severe SARS-CoV-2 infection. N Engl J Med 382(23):2268–2270. https://doi.org/10.1056/NEJMc2008597CrossRefPubMed

Capasso R, Miceli G (2001) Esame neuropsicologico per l’afasia. Springer

Spinnler H, Tognoni G (1987) Standardizzazione e taratura italiana di test neuropsicologici. Ital J Neurol Sci 6(Suppl. 8):25–27

Title: COVID-19 presenting with agraphia and conduction aphasia in a patient with left-hemisphere ischemic stroke
Authors: Konstantinos Priftis
Lorella Algeri
Stella Villella
Maria Simonetta Spada
Publication date: 01-12-2020
Publisher: Springer International Publishing
Keywords: Stroke
SARS-CoV-2
Confusion
COVID-19
Aphasia
Apraxia
Published in: Neurological Sciences / Issue 12/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04768-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

COVID-19 presenting with agraphia and conduction aphasia in a patient with left-hemisphere ischemic stroke

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 12/2020

Locking down the CGRP pathway during the COVID-19 pandemic lockdown: the PandeMig study

Thiazolidinedione use is associated with reduced risk of Parkinson’s disease in patients with diabetes: a meta-analysis of real-world evidence

Application of the p9NORM correction method to timed neuropsychological tests in Parkinson’s disease and multiple system atrophy

West syndrome: a comprehensive review

Nerve ultrasonography findings as possible pitfall in differential diagnosis between hereditary transthyretin amyloidosis with polyneuropathy and chronic inflammatory demyelinating polyneuropathy

Wearable haptic anklets for gait and freezing improvement in Parkinson’s disease: a proof-of-concept study