Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Annals of Hematology
Published in: Annals of Hematology 10/2020

01-10-2020 | Chronic Myeloid Leukemia | Letter to the Editor

Identification of a novel ETV6 truncated fusion gene in myeloproliferative neoplasm, unclassifiable with t(4;12)(q12;p13)

Authors: Ling Zhang, Man Wang, Zheng Wang, Zhao Zeng, Lijun Wen, Yi Xu, Li Yao, Jiannong Cen, Hongzhi Li, Jinlan Pan, Aining Sun, Depei Wu, Suning Chen, Liang Ma, Xiaofei Yang

Published in: Annals of Hematology | Issue 10/2020

Login to get access

Excerpt

Dear Editor. …
Appendix
Available only for authorised users
Literature
1.
Wlodarska I, Mecucci C, Baens M, Marynen P, van den Berghe H (1996) ETV6 gene rearrangements in hematopoietic malignant disorders. Leuk Lymphoma 23(3–4):287–295CrossRef
2.
De Braekeleer E, Douet-Guilbert N, Morel F, Le Bris MJ, Basinko A, De Braekeleer M (2012) ETV6 fusion genes in hematological malignancies: a review. Leuk Res 36(8):945–961CrossRef
3.
Murga Penas EM, Cools J, Algenstaedt P, Hinz K, Seeger D, Schafhausen P et al (2003) A novel cryptic translocation t(12;17)(p13;p12-p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene. Genes Chromosomes Cancer 37(1):79–83CrossRef
4.
Odero MD, Vizmanos JL, Roman JP, Lahortiga I, Panizo C, Calasanz MJ et al (2002) A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome. Genes Chromosomes Cancer 35(1):11–19CrossRef
5.
Suto Y, Sato Y, Smith SD, Rowley JD, Bohlander SK (1997) A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line. Genes Chromosomes Cancer 18(4):254–268CrossRef
6.
Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM et al (2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 127(20):2391–2405CrossRef
7.
Oikawa T, Yamada T (2003) Molecular biology of the Ets family of transcription factors. Gene. 303:11–34CrossRef
8.
Cools J, Mentens N, Odero MD, Peeters P, Wlodarska I, Delforge M, Hagemeijer A, Marynen P (2002) Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13). Blood. 99(5):1776–1784CrossRef
9.
Gianelli U, Cattaneo D, Bossi A, Cortinovis I, Boiocchi L, Liu YC, Augello C, Bonometti A, Fiori S, Orofino N, Guidotti F, Orazi A, Iurlo A (2017) The myeloproliferative neoplasms, unclassifiable: clinical and pathological considerations. Mod Pathol 30(7):1043CrossRef
Metadata
Title
Identification of a novel ETV6 truncated fusion gene in myeloproliferative neoplasm, unclassifiable with t(4;12)(q12;p13)
Authors
Ling Zhang
Man Wang
Zheng Wang
Zhao Zeng
Lijun Wen
Yi Xu
Li Yao
Jiannong Cen
Hongzhi Li
Jinlan Pan
Aining Sun
Depei Wu
Suning Chen
Liang Ma
Xiaofei Yang
Publication date
01-10-2020
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 10/2020
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-020-04207-y

Other articles of this Issue 10/2020

Annals of Hematology 10/2020 Go to the issue

Review Article

Germinotropic lymphoproliferative disorder: a systematic review

Original Article

Treatment of pediatric primary hemophagocytic lymphohistiocytosis with the HLH-94/2004 regimens and hematopoietic stem cell transplantation in China

Review Article

Long non-coding RNAs and MYC association in hematological malignancies

Letter to the Editor

Battle of the clones: paroxysmal nocturnal hemoglobinuria vs myelodysplastic syndrome

Original Article

Predictive factors for response and survival in elderly acute myeloid leukemia patients treated with hypomethylating agents: a real-life experience

Original Article

Tacrolimus ameliorates thrombocytopenia in an ITP mouse model
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits