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Published in: International Urogynecology Journal 10/2011

01-10-2011 | Review Article

Genetics of pelvic organ prolapse: crossing the bridge between bench and bedside in urogynecologic research

Authors: Maria Augusta Tezelli Bortolini, Diaa E. E. Rizk

Published in: International Urogynecology Journal | Issue 10/2011

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Abstract

An increasing number of scientists have studied the molecular and biochemical basis of pelvic organ prolapse (POP). The extracellular matrix content of the pelvic floor is the major focus of those investigations and pointed for potential molecular markers of the dysfunction. The identification of women predisposed to develop POP would help in the patients’ management and care. This article includes a critical analysis of the literature up to now; discusses implications for future research and the role of the genetics in POP.
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Metadata
Title
Genetics of pelvic organ prolapse: crossing the bridge between bench and bedside in urogynecologic research
Authors
Maria Augusta Tezelli Bortolini
Diaa E. E. Rizk
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 10/2011
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-011-1502-4

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