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Open Access 01-02-2010 | Year in Review 2009

Year in review in Intensive Care Medicine 2009: I. Pneumonia and infections, sepsis, outcome, acute renal failure and acid base, nutrition and glycaemic control

Authors: Massimo Antonelli, Elie Azoulay, Marc Bonten, Jean Chastre, Giuseppe Citerio, Giorgio Conti, Daniel De Backer, François Lemaire, Herwig Gerlach, Goran Hedenstierna, Michael Joannidis, Duncan Macrae, Jordi Mancebo, Salvatore M. Maggiore, Alexandre Mebazaa, Jean-Charles Preiser, Jerôme Pugin, Jan Wernerman, Haibo Zhang

Published in: Intensive Care Medicine | Issue 2/2010

Excerpt

Any delay in adequate antibiotic treatment may compromise the outcome of ventilator-associated pneumonia (VAP). However, the diagnosis and optimal treatment of VAP remain a challenge for intensivists. Jung et al. [1] assessed the potential impact of using results of once-a-week routine quantitative endotracheal aspirate (EA) cultures to guide initial antibiotic treatment in a study of 113 episodes of bronchoalveolar lavage-confirmed VAP. When guided by EA, the initial antibiotic regimen was adequate in 85% of situations, a proportion significantly superior to that resulting from application of the ATS guidelines (73%). When clinicians did not have a pre-VAP EA to guide their treatment (EA not performed group), only 61% of treatments were adequate, confirming that routine surveillance cultures may help to improve the adequacy of empiric antibiotic therapy for VAP. …

Jung B, Sebbane M, Chanques G, Courouble P, Verzilli D, Perrigault PF, Jean-Pierre H, Eledjam JJ, Jaber S (2009) Previous endotracheal aspirate allows guiding the initial treatment of ventilator-associated pneumonia. Intensive Care Med 35:101–107CrossRefPubMed

Patman S, Jenkins S, Stiller K (2009) Physiotherapy does not prevent, or hasten recovery from, ventilator-associated pneumonia in patients with acquired brain injury. Intensive Care Med 35:258–265CrossRefPubMed

Martinez JA, Delgado E, Marti S, Marco F, Vila J, Mensa J, Torres A, Codina C, Trilla A, Soriano A, Alquezar A, Castro P, Nicolas JM (2009) Influence of antipseudomonal agents on Pseudomonas aeruginosa colonization and acquisition of resistance in critically ill medical patients. Intensive Care Med 35:439–447CrossRefPubMed

Rodriguez A, Lisboa T, Blot S, Martin-Loeches I, Sole-Violan J, De Mendoza D, Rello J (2009) Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough. Intensive Care Med 35:430–438CrossRefPubMed

Knight DJ, Gardiner D, Banks A, Snape SE, Weston VC, Bengmark S, Girling KJ (2009) Effect of synbiotic therapy on the incidence of ventilator associated pneumonia in critically ill patients: a randomised, double-blind, placebo-controlled trial. Intensive Care Med 35:854–861CrossRefPubMed

Baldesi O, Michel F, Guervilly C, Embriaco N, Granfond A, La Scola B, Portugal H, Papazian L (2009) Bacterial ventilator-associated pneumonia: bronchoalveolar lavage results are not influenced by dilution. Intensive Care Med 35:1210–1215CrossRefPubMed

Oudhuis GJ, Beuving J, Bergmans D, Stobberingh EE, ten Velde G, Linssen CF, Verbon A (2009) Soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid is not predictive for ventilator-associated pneumonia. Intensive Care Med 35:1265–1270CrossRefPubMed

Jiyong J, Tiancha H, Wei C, Huahao S (2009) Diagnostic value of the soluble triggering receptor expressed on myeloid cells-1 in bacterial infection: a meta-analysis. Intensive Care Med 35:587–595CrossRefPubMed

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Meyer E, Lapatschek M, Bechtold A, Schwarzkopf G, Gastmeier P, Schwab F (2009) Impact of restriction of third generation cephalosporins on the burden of third generation cephalosporin resistant K. pneumoniae and E. coli in an ICU. Intensive Care Med 35:862–870CrossRefPubMed

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Title: Year in review in Intensive Care Medicine 2009: I. Pneumonia and infections, sepsis, outcome, acute renal failure and acid base, nutrition and glycaemic control
Authors: Massimo Antonelli
Elie Azoulay
Marc Bonten
Jean Chastre
Giuseppe Citerio
Giorgio Conti
Daniel De Backer
François Lemaire
Herwig Gerlach
Goran Hedenstierna
Michael Joannidis
Duncan Macrae
Jordi Mancebo
Salvatore M. Maggiore
Alexandre Mebazaa
Jean-Charles Preiser
Jerôme Pugin
Jan Wernerman
Haibo Zhang
Publication date: 01-02-2010
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 2/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1742-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Year in review in Intensive Care Medicine 2009: I. Pneumonia and infections, sepsis, outcome, acute renal failure and acid base, nutrition and glycaemic control

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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