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Diabetologia
Published in: Diabetologia 9/2010

01-09-2010 | Commentary

The glucagon-producing alpha cell: an electrophysiologically exceptional cell

Authors: M. Braun, P. Rorsman

Published in: Diabetologia | Issue 9/2010

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Abstract

Activation of potassium channels normally serves to reduce cellular activity but recent data indicate that the glucagon-secreting alpha cells are different in this respect and that inhibition of voltage-gated potassium channels results in a paradoxical inhibition of glucagon secretion. Here we discuss these findings and attempt to provide a model for the regulation of glucagon secretion that incorporates these observations.
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Metadata
Title
The glucagon-producing alpha cell: an electrophysiologically exceptional cell
Authors
M. Braun
P. Rorsman
Publication date
01-09-2010
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 9/2010
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-010-1823-8

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Keynote webinar | Spotlight on medication adherence

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