Issue 9/2010
Content (37 Articles)
Glucose-lowering therapies and cancer risk: the trials and tribulations of trials and observations
J. A. Johnson, Y. Yasui
The glucagon-producing alpha cell: an electrophysiologically exceptional cell
M. Braun, P. Rorsman
Tribbles homologue 3 (TRIB3) and the insulin-resistance genes in type 2 diabetes
F. Beguinot
Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials
P. D. Home, S. E. Kahn, N. P. Jones, D. Noronha, H. Beck-Nielsen, G. Viberti
Ability of traditional lipid ratios and apolipoprotein ratios to predict cardiovascular risk in people with type 2 diabetes
M.-R. Taskinen, P. J. Barter, C. Ehnholm, D. R. Sullivan, K. Mann, J. Simes, J. D. Best, S. Hamwood, A. C. Keech
Autonomic neuropathy predisposes to rosiglitazone-induced vascular leakage in insulin-treated patients with type 2 diabetes: a randomised, controlled trial on thiazolidinedione-induced vascular leakage
A. J. Rennings, P. Smits, M. W. Stewart, C. J. Tack
Diabetes, prediabetes and cancer mortality
X. H. Zhou, Q. Qiao, B. Zethelius, K. Pyörälä, S. Söderberg, A. Pajak, C. D. A. Stehouwer, R. J. Heine, P. Jousilahti, G. Ruotolo, P. M. Nilsson, G. Calori, J. Tuomilehto
Low-intensity physical activity is associated with reduced risk of incident type 2 diabetes in older adults: evidence from the English Longitudinal Study of Ageing
P. Demakakos, M. Hamer, E. Stamatakis, A. Steptoe
Proteinuria modifies the effects of physical activity on total and cardiovascular disease mortality rates in patients with type 2 diabetes
T. Vepsäläinen, M. Soinio, S. Lehto, A. Juutilainen, M. Laakso, T. Rönnemaa
Recent population changes in HbA1c and fasting insulin concentrations among US adults with preserved glucose homeostasis
Y. J. Cheng, H. S. Kahn, E. W. Gregg, G. Imperatore, L. S. Geiss
Homeostasis model assessment of insulin resistance and the risk of cardiovascular events in middle-aged non-diabetic Japanese men
K. Nakamura, M. Sakurai, K. Miura, Y. Morikawa, M. Ishizaki, K. Yoshita, T. Kido, Y. Naruse, H. Nakagawa
DDOST, PRKCSH and LGALS3, which encode AGE-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes
A. Hoverfelt, R. Sallinen, J. M. Söderlund, C. Forsblom, K. Pettersson-Fernholm, M. Parkkonen, P.-H. Groop, M. Wessman
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
E. A. Andersson, K. Pilgaard, C. Pisinger, M. N. Harder, N. Grarup, K. Færch, P. Poulsen, D. R. Witte, T. Jørgensen, A. Vaag, T. Hansen, O. Pedersen
Voltage-dependent K+ channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans
A. F. Spigelman, X. Dai, P. E. MacDonald
ADP mediates inhibition of insulin secretion by activation of P2Y13 receptors in mice
S. Amisten, S. Meidute-Abaraviciene, C. Tan, B. Olde, I. Lundquist, A. Salehi, D. Erlinge
The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion
P. Lebrun, E. Cognard, P. Gontard, R. Bellon-Paul, C. Filloux, M. F. Berthault, C. Magnan, J. Ruberte, M. Luppo, A. Pujol, N. Pachera, A. Herchuelz, F. Bosch, E. Van Obberghen
Subplasmalemmal Ca2+ measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretion
M. A. Ravier, R. Cheng-Xue, A. E. Palmer, J. C. Henquin, P. Gilon
Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNγ
G. Fousteri, A. Dave, A. Bot, T. Juntti, S. Omid, M. von Herrath
Aberrant hepatic TRIB3 gene expression in insulin-resistant obese humans
H. Oberkofler, A. Pfeifenberger, S. Soyal, T. Felder, P. Hahne, K. Miller, F. Krempler, W. Patsch
Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes
M. Hey-Mogensen, K. Højlund, B. F. Vind, L. Wang, F. Dela, H. Beck-Nielsen, M. Fernström, K. Sahlin
Naturally occurring R225W mutation of the gene encoding AMP-activated protein kinase (AMPK)γ3 results in increased oxidative capacity and glucose uptake in human primary myotubes
S. A. Crawford, S. R. Costford, C. Aguer, S. C. Thomas, R. A. deKemp, J. N. DaSilva, D. Lafontaine, M. Kendall, R. Dent, R. S. B. Beanlands, R. McPherson, M.-E. Harper
Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action
M. Friedrichsen, P. Poulsen, E. A. Richter, B. F. Hansen, J. B. Birk, R. Ribel-Madsen, K. Stender-Petersen, E. Nilsson, H. Beck-Nielsen, A. Vaag, J. F. P. Wojtaszewski
Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1α) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats
C. R. Benton, G. P. Holloway, X.-X. Han, Y. Yoshida, L. A. Snook, J. Lally, J. F. C. Glatz, J. J. F. P. Luiken, A. Chabowski, A. Bonen
Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes
A. Willcox, S. J. Richardson, A. J. Bone, A. K. Foulis, N. G. Morgan
Capillary pressure may predict preclinical changes in the eye
K. M. Gooding, J. E. Tooke, H. von Lany, M. Mitra, R. Ling, C. I. Ball, D. Mawson, K. Skinner, A. C. Shore
QT interval prolongation during spontaneous episodes of hypoglycaemia in type 1 diabetes: the impact of heart rate correction
T. F. Christensen, L. Tarnow, J. Randløv, L. E. Kristensen, J. J. Struijk, E. Eldrup, O. K. Hejlesen
Retinal fractal dimension is increased in persons with diabetes but not impaired glucose metabolism: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study
J. W. Y. Yau, R. Kawasaki, F. M. A. Islam, J. Shaw, P. Zimmet, J. J. Wang, T. Y. Wong
Transgenic mice overproducing human thioredoxin-1, an antioxidative and anti-apoptotic protein, prevents diabetic embryopathy
Y. Kamimoto, T. Sugiyama, T. Kihira, L. Zhang, N. Murabayashi, T. Umekawa, K. Nagao, N. Ma, N. Toyoda, J. Yodoi, N. Sagawa
Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats
A. Kuwabara, M. Satoh, N. Tomita, T. Sasaki, N. Kashihara
Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes
R. Boizel, G. Bruttmann, P. Y. Benhamou, S. Halimi, F. Stanke-Labesque
Should the algorithm for the treatment of type 2 diabetes be evidence-based?
P.-J. Guillausseau