Issue 1/2018
Content (371 Articles)
Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma
Ruzena Stranska, Laurens Gysbrechts, Jens Wouters, Pieter Vermeersch, Katarzyna Bloch, Daan Dierickx, Graciela Andrei, Robert Snoeck
Placental hypoxia-regulating network in relation to birth weight and ponderal index: the ENVIRONAGE Birth Cohort Study
Karen Vrijens, Maria Tsamou, Narjes Madhloum, Wilfried Gyselaers, Tim S. Nawrot
Gamma-delta (γδ) T cells: friend or foe in cancer development?
Yijing Zhao, Chao Niu, Jiuwei Cui
Accuracy of four mononucleotide-repeat markers for the identification of DNA mismatch-repair deficiency in solid tumors
Yuko Takehara, Takeshi Nagasaka, Akihiro Nyuya, Tomoko Haruma, Junko Haraga, Yoshiko Mori, Keiichiro Nakamura, Toshiyoshi Fujiwara, C. Richard Boland, Ajay Goel
Association between non-cholesterol sterol concentrations and Achilles tendon thickness in patients with genetic familial hypercholesterolemia
Lucía Baila-Rueda, Itziar Lamiquiz-Moneo, Estíbaliz Jarauta, Rocío Mateo-Gallego, Sofía Perez-Calahorra, Victoria Marco-Benedí, Ana M. Bea, Ana Cenarro, Fernando Civeira
TIPE2 suppresses progression and tumorigenesis of esophageal carcinoma via inhibition of the Wnt/β-catenin pathway
Linan Zhu, Xudong Zhang, Xiaorui Fu, Zhaoming Li, Zhenchang Sun, Jingjing Wu, Xinhua Wang, Feng Wang, Xiangke Li, Songtao Niu, Mengjie Ding, Zhenzhen Yang, Wanqiu Yang, Meifeng Yin, Lei Zhang, Mingzhi Zhang
Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence
Ryungsa Kim
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer
Zhen-Fei Zhang, Han-Rong Zhang, Qing-Yan Zhang, Shu-Yu Lai, Yu-Zhen Feng, Yi Zhou, Si-Rong Zheng, Rong Shi, Jue-Yu Zhou
Effect of the replacement of dietary vegetable oils with a low dose of extravirgin olive oil in the Mediterranean Diet on cognitive functions in the elderly
Elisa Mazza, Antonietta Fava, Yvelise Ferro, Stefania Rotundo, Stefano Romeo, Domenico Bosco, Arturo Pujia, Tiziana Montalcini
Comparative salivary proteomics analysis of children with and without dental caries using the iTRAQ/MRM approach
Kun Wang, Yufei Wang, Xiuqing Wang, Qian Ren, Sili Han, Longjiang Ding, Zhongcheng Li, Xuedong Zhou, Wei Li, Linglin Zhang
The prognostic value of preoperative prognostic nutritional index in patients with hypopharyngeal squamous cell carcinoma: a retrospective study
Lu-Lu Ye, Ronald Wihal Oei, Fang-Fang Kong, Cheng-Run Du, Rui-Ping Zhai, Qing-Hai Ji, Chao-Su Hu, Hong-Mei Ying
Enhanced clinical-scale manufacturing of TCR transduced T-cells using closed culture system modules
Jianjian Jin, Nikolaos Gkitsas, Vicki S. Fellowes, Jiaqiang Ren, Steven A. Feldman, Christian S. Hinrichs, David F. Stroncek, Steven L. Highfill
Chronic diseases, inflammation, and spices: how are they linked?
Ajaikumar B. Kunnumakkara, Bethsebie L. Sailo, Kishore Banik, Choudhary Harsha, Sahdeo Prasad, Subash Chandra Gupta, Alok Chandra Bharti, Bharat B. Aggarwal
Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization
Jianling Zou, Ying Liu, Jingyuan Wang, Zhentao Liu, Zhihao Lu, Zuhua Chen, Zhongwu Li, Bin Dong, Wenwen Huang, Yanyan Li, Jing Gao, Lin Shen
Toolbox for Research, or how to facilitate a central data management in small-scale research projects
Martin Bialke, Henriette Rau, Oliver C. Thamm, Ronny Schuldt, Peter Penndorf, Arne Blumentritt, Robert Gött, Jens Piegsa, Thomas Bahls, Wolfgang Hoffmann
Voltammetric analysis for fast and inexpensive diagnosis of urinary tract infection: a diagnostic study
Diana Lelli, Claudio Pedone, Pamela Alemanno, Alessandra Bertini, Claudia Di Gioia, Sara Fazzina, Giorgio Pennazza, Marco Santonico, Simone Grasso, Alessandro Zompanti, Silvia Angeletti, Raffaele Antonelli Incalzi
Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis
Claudio Carini, Ewan Hunter, Duncan Porter, Iain McInnes, David Reid, Stuart H. Ralston, Neil Basu, Leon Collis, Carl S. Goodyear, Janet Liversidge, Caron Paterson, Jane Hair, Sharon Kean, Ashley Gilmour, Margaret Duncan, Susan Fraser, Lisa Hutton, John Harvie, Vinod Kumar, Mike McMahon, Robin Munro, John Larkin, Neil McKay, John McLaren, David M. Reid, Duncan Porter, Ruth Richmond, Gillian Roberts, Sarah Saunders, Hilary Wilson, Aroul S. Ramadass, Jayne Green, Alexandre Akoulitchev, Iain B. McInnes, Carl S. Goodyear
Myeloid-derived suppressor cells in transplantation: the dawn of cell therapy
Weitao Zhang, Jiawei Li, Guisheng Qi, Guowei Tu, Cheng Yang, Ming Xu
Investigation of genetic variation and lifestyle determinants in vitamin D levels in Arab individuals
Massimo Mezzavilla, Sara Tomei, Fadi Alkayal, Motasem Melhem, Maisa M. Ali, Monira Al-Arouj, Abdullah Bennakhi, Osama Alsmadi, Naser Elkum
Improvement of severe myalgic encephalomyelitis/chronic fatigue syndrome symptoms following surgical treatment of cervical spinal stenosis
Peter C. Rowe, Colleen L. Marden, Scott Heinlein, Charles C. Edwards II
Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy
Elisa Melucci, Beatrice Casini, Livia Ronchetti, Laura Pizzuti, Francesca Sperati, Matteo Pallocca, Francesca De Nicola, Frauke Goeman, Enzo Gallo, Carla Azzurra Amoreo, Domenico Sergi, Irene Terrenato, Patrizia Vici, Luigi Di Lauro, Maria Grazia Diodoro, Edoardo Pescarmona, Maddalena Barba, Marco Mazzotta, Marcella Mottolese, Maurizio Fanciulli, Gennaro Ciliberto, Ruggero De Maria, Simonetta Buglioni, Marcello Maugeri-Saccà
Immune monitoring and TCR sequencing of CD4 T cells in a long term responsive patient with metastasized pancreatic ductal carcinoma treated with individualized, neoepitope-derived multipeptide vaccines: a case report
Katja Sonntag, Hisayoshi Hashimoto, Matthias Eyrich, Moritz Menzel, Max Schubach, Dennis Döcker, Florian Battke, Carolina Courage, Helmut Lambertz, Rupert Handgretinger, Saskia Biskup, Karin Schilbach
Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons
Amy Wallis, Michelle Ball, Henry Butt, Donald P. Lewis, Sandra McKechnie, Phillip Paull, Amber Jaa-Kwee, Dorothy Bruck
Turning the tables on cytomegalovirus: targeting viral Fc receptors by CARs containing mutated CH2–CH3 IgG spacer domains
Julia Proff, Charlotte U. Brey, Armin Ensser, Wolfgang Holter, Manfred Lehner
Facial nerve stimulation in normal pigs and healthy human volunteers: transitional development of a medical device for the emergency treatment of ischemic stroke
Olivia Sanchez, Andrea García, Fernando Castro-Prado, Miriam Perez, Rafael Lara-Estrada, Martin Ramirez-Meza, Montserrat Godinez, Michael L. Coco, Joaquín Azpiroz, Mark K. Borsody, Emilio Sacristán
Academic medical centers as innovation ecosystems to address population –omics challenges in precision medicine
Patrick J. Silva, Valerie M. Schaibley, Kenneth S. Ramos
Non-viral gene delivery systems for tissue repair and regeneration
Pan Wu, Haojiao Chen, Ronghua Jin, Tingting Weng, Jon Kee Ho, Chuangang You, Liping Zhang, Xingang Wang, Chunmao Han
Double-negative (CD27−IgD−) B cells are expanded in NSCLC and inversely correlate with affinity-matured B cell populations
Sara M. Centuori, Cecil J. Gomes, Samuel S. Kim, Charles W. Putnam, Brandon T. Larsen, Linda L. Garland, David W. Mount, Jesse D. Martinez
Immunomodulatory plasticity of mesenchymal stem cells: a potential key to successful solid organ transplantation
Urvashi Kaundal, Upma Bagai, Aruna Rakha
Computational analysis identifies putative prognostic biomarkers of pathological scarring in skin wounds
Sridevi Nagaraja, Lin Chen, Luisa A. DiPietro, Jaques Reifman, Alexander Y. Mitrophanov
Correction to: Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: a multivariate analysis of 214 cases
Maria A. Pizzichetta, Daniela Massi, Mario Mandalà, Paola Queirolo, Ignazio Stanganelli, Vincenzo De Giorgi, Giovanni Ghigliotti, Stefano Cavicchini, Pietro Quaglino, Maria T. Corradin, Pietro Rubegni, Mauro Alaibac, Stefano Astorino, Fabrizio Ayala, Serena Magi, Laura Mazzoni, Maria Ausilia Manganoni, Renato Talamini, Diego Serraino, Giuseppe Palmieri
Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients
Ákos Tényi, Isaac Cano, Francesco Marabita, Narsis Kiani, Susana G. Kalko, Esther Barreiro, Pedro de Atauri, Marta Cascante, David Gomez-Cabrero, Josep Roca
Telomere attrition in heart failure: a flow-FISH longitudinal analysis of circulating monocytes
Iris Teubel, Elena Elchinova, Santiago Roura, Marco A. Fernández, Carolina Gálvez-Montón, Pedro Moliner, Marta de Antonio, Josep Lupón, Antoni Bayés-Genís
Bronchopulmonary dysplasia: clinical aspects and preventive and therapeutic strategies
Nicola Principi, Giada Maria Di Pietro, Susanna Esposito
A probiotic complex, rosavin, zinc, and prebiotics ameliorate intestinal inflammation in an acute colitis mouse model
Jin-Sil Park, JeongWon Choi, Ji Ye Kwon, Kyung-Ah Jung, Chul Woo Yang, Sung-Hwan Park, Mi-La Cho
Tumor-promoting properties of miR-8084 in breast cancer through enhancing proliferation, suppressing apoptosis and inducing epithelial–mesenchymal transition
Yujing Gao, Hongning Ma, Chanchan Gao, Ye Lv, XueHua Chen, Rongrong Xu, Miao Sun, Xinrui Liu, Xiaohong Lu, Xiuying Pei, Pu Li
Correction to: Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons
Amy Wallis, Michelle Ball, Henry Butt, Donald P. Lewis, Sandra McKechnie, Phillip Paull, Amber Jaa‑Kwee, Dorothy Bruck
Correction to: Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma
Alexander W. Eckert, Claudia Wickenhauser, Paul C. Salins, Matthias Kappler, Juergen Bukur, Barbara Seliger
Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer
Honghao Yu, Weihu Long, Xuezeng Zhang, Kaixiang Xu, Jianxiong Guo, Heng Zhao, Honghui Li, Yubo Qing, Weirong Pan, Baoyu Jia, Hong-Ye Zhao, Xingxu Huang, Hong-Jiang Wei
Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children
Yong Song, Hilda Higgins, Jing Guo, Katrina Harrison, En Nee Schultz, Belinda J. Hales, Eric K. Moses, Jack Goldblatt, Nicholas Pachter, Guicheng Zhang
Identification of candidate genes associated with fibromyalgia susceptibility in southern Spanish women: the al-Ándalus project
Fernando Estévez-López, Daniel Camiletti-Moirón, Virginia A. Aparicio, Víctor Segura-Jiménez, Inmaculada C. Álvarez-Gallardo, Alberto Soriano-Maldonado, Milkana Borges-Cosic, Pedro Acosta-Manzano, Rinie Geenen, Manuel Delgado-Fernández, Luis J. Martínez-González, Jonatan R. Ruiz, María J. Álvarez-Cubero
Association of chronic fatigue syndrome with premature telomere attrition
Mangalathu S. Rajeevan, Janna Murray, Lisa Oakley, Jin-Mann S. Lin, Elizabeth R. Unger
A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway
Micaela Freitas, Fábio Ferreira, Sónia Carvalho, Fernanda Silva, Paula Lopes, Luís Antunes, Sofia Salta, Francisca Diniz, Lúcio Lara Santos, José Flávio Videira, Rui Henrique, Carmen Jerónimo
Identification and validation a TGF-β-associated long non-coding RNA of head and neck squamous cell carcinoma by bioinformatics method
Teng Huang, Wei Huang, Hong Lu, Bi-yun Zhang, Jun Ma, Di Zhao, Yi-jun Wang, Da-hai Yu, Xia He
Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia
Manman Deng, Jie Zha, Zhiwu Jiang, Xian Jia, Yuanfei Shi, Peng Li, Xiao Lei Chen, Zhihong Fang, Zhiqiang Du, Bing Xu
Distinct alterations of CD68+CD163+ M2-like macrophages and myeloid-derived suppressor cells in newly diagnosed primary immune thrombocytopenia with or without CR after high-dose dexamethasone treatment
Xia Shao, Boting Wu, Luya Cheng, Feng Li, Yanxia Zhan, Chanjuan Liu, Lili Ji, Zhihui Min, Yang Ke, Lihua Sun, Hao Chen, Yunfeng Cheng
Safety, tolerability and efficacy of intra-articular Progenza in knee osteoarthritis: a randomized double-blind placebo-controlled single ascending dose study
D. Kuah, S. Sivell, T. Longworth, K. James, A. Guermazi, F. Cicuttini, Y. Wang, S. Craig, G. Comin, D. Robinson, J. Wilson
CD133 expression in cancer cells predicts poor prognosis of non-mucin producing intrahepatic cholangiocarcinoma
Xiaobo Cai, Jun Li, Xiaodong Yuan, Jingbo Xiao, Steven Dooley, Xinjian Wan, Honglei Weng, Lungen Lu
Physiological and molecular effects of interleukin-18 administration on the mouse kidney
Kyosuke Yamanishi, Keiichiro Mukai, Takuya Hashimoto, Kaoru Ikubo, Keiji Nakasho, Yosif El-Darawish, Wen Li, Daisuke Okuzaki, Yuko Watanabe, Tetsu Hayakawa, Hiroshi Nojima, Hiromichi Yamanishi, Haruki Okamura, Hisato Matsunaga
Allogeneic mesenchymal stem cells as induction therapy are safe and feasible in renal allografts: pilot results of a multicenter randomized controlled trial
Qipeng Sun, Zhengyu Huang, Fei Han, Ming Zhao, Ronghua Cao, Daqiang Zhao, Liangqing Hong, Ning Na, Heng Li, Bin Miao, Jianmin Hu, Fanhang Meng, Yanwen Peng, Qiquan Sun
The role of atorvastatin in suppressing tumor growth of uterine fibroids
Zhaojun Shen, Saisai Li, Bo Sheng, Qi Shen, Lu-Zhe Sun, Haiyan Zhu, Xueqiong Zhu
Study on the progression types of cancer in patients with breast cancer undergoing eribulin chemotherapy and tumor microenvironment
Shinichiro Kashiwagi, Gen Tsujio, Yuka Asano, Wataru Goto, Koji Takada, Katsuyuki Takahashi, Tamami Morisaki, Hisakazu Fujita, Tsutomu Takashima, Shuhei Tomita, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira
Low dose Naltrexone for induction of remission in inflammatory bowel disease patients
Mitchell R. K. L. Lie, Janine van der Giessen, Gwenny M. Fuhler, Alison de Lima, Maikel P. Peppelenbosch, Cokkie van der Ent, C. Janneke van der Woude
The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis
Erik Lindström, Biljana Rizoska, Karin Tunblad, Charlotte Edenius, Alison M. Bendele, Don Maul, Michael Larson, Neha Shah, Valerie Yoder Otto, Chris Jerome, Urszula Grabowska
Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis
Neil H. Riordan, Isabela Morales, Giselle Fernández, Nicole Allen, Neal E. Fearnot, Michael E. Leckrone, Dedra Jones Markovich, Darla Mansfield, Dorita Avila, Amit N. Patel, Santosh Kesari, Jorge Paz Rodriguez
Alloxan-induced diabetes exacerbates coronary atherosclerosis and calcification in Ossabaw miniature swine with metabolic syndrome
Jill K. Badin, Ayeeshik Kole, Benjamin Stivers, Victor Progar, Anisha Pareddy, Mouhamad Alloosh, Michael Sturek
Effect of γ-secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis-like skin inflammation
Lei Ma, Haibo Xue, Ruiqun Qi, Yanqin Wang, Libing Yuan
Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome
Masood Abu-Halima, Mustafa Kahraman, Dominic Henn, Tanja Rädle-Hurst, Andreas Keller, Hashim Abdul-Khaliq, Eckart Meese
T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans
Franklin R. Toapanta, Paula J. Bernal, Karen L. Kotloff, Myron M. Levine, Marcelo B. Sztein
Identification of the cellular components involved in de novo immune hepatitis: a quantitative immunohistochemical analysis
Elena Aguado-Domínguez, Lourdes Gómez, José Manuel Sousa, Miguel Ángel Gómez-Bravo, Antonio Núñez-Roldán, Isabel Aguilera
RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells
George Inana, Christopher Murat, Weijun An, Xiang Yao, Ian R. Harris, Jing Cao
Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells
Tiziana Alberio, Greta Forlani, Marta Lualdi, Giovanna Tosi, Roberto S. Accolla, Mauro Fasano
Comparison of human bone marrow stromal cells cultured in human platelet growth factors and fetal bovine serum
Jiaqiang Ren, Dawn Ward, Steven Chen, Katherine Tran, Ping Jin, Marianna Sabatino, Pamela G. Robey, David F. Stroncek
Relationship between mismatch repair immunophenotype and long-term survival in patients with resected periampullary adenocarcinoma
Margareta Heby, Sebastian Lundgren, Björn Nodin, Jacob Elebro, Jakob Eberhard, Karin Jirström
HNA-3a and HNA-3b antigens among 9 ethnic populations and the Han population in Southwest China
Guo-Jin Ou, Pin-Can Su, Hao Yu, Xin Ji, Fan Liu, Sheng-Lan Wang, Yu-Jie Kong, Ling Li, Jue Wang, Zhong Liu, Willy Albert Flegel
MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia
Qiu-Ling Ma, Jing-Han Wang, Min Yang, Huan-ping Wang, Jie Jin
Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease
Yung-Che Chen, Meng-Chih Lin, Chih-Hung Lee, Shih-Feng Liu, Chin-Chou Wang, Wen-Feng Fang, Tung-Ying Chao, Chao-Chien Wu, Yu-Feng Wei, Huang-Chih Chang, Chia-Cheng Tsen, Hung-Chen Chen
Intermittent PTH administration improves alveolar bone formation in type 1 diabetic rats with periodontitis
Ji-Hye Kim, Ae Ri Kim, Yun Hui Choi, Aeryun Kim, Yongsung Sohn, Gye-Hyeong Woo, Jeong-Heon Cha, Eun-Jung Bak, Yun-Jung Yoo
Oral Escherichia coli expressing IL-35 meliorates experimental colitis in mice
Baoren Zhang, Yi Liu, Xu Lan, Xiaoxi Xu, Xiaoning Zhang, Xiang Li, Yiming Zhao, Guang Li, Caigan Du, Shanzheng Lu, Hao Wang
Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling
Ping-er Wang, Lei Zhang, Jun Ying, Xing Jin, Cheng Luo, Shibing Xu, Rui Dong, Luwei Xiao, Peijian Tong, Hongting Jin
Improving cancer detection through combinations of cancer and immune biomarkers: a modelling approach
Raluca Eftimie, Esraa Hassanein
OX40L induces helper T cell differentiation during cell immunity of asthma through PI3K/AKT and P38 MAPK signaling pathway
Li Huang, Meijuan Wang, Yongdong Yan, Wenjing Gu, Xinxing Zhang, Jiahong Tan, Huiming Sun, Wei Ji, Zhengrong Chen
The influence of diet on anti-cancer immune responsiveness
Laura Soldati, Laura Di Renzo, Emilio Jirillo, Paolo A. Ascierto, Francesco M. Marincola, Antonino De Lorenzo
Association of adiponectin gene variants with idiopathic recurrent miscarriage according to obesity status: a case–control study
Maryam Dendana, Wael Bahia, Ramzi R. Finan, Mariam Al-Mutawa, Wassim Y. Almawi
Telomerase promoter mutations in human immunodeficiency virus-related conjunctiva neoplasia
Noemy Starita, Luigi Buonaguro, Franco M. Buonaguro, Maria Lina Tornesello
Dexmedetomidine attenuates lung apoptosis induced by renal ischemia–reperfusion injury through α2AR/PI3K/Akt pathway
Juanjuan Li, Qian Chen, Xinhai He, Azeem Alam, Jiaolin Ning, Bin Yi, Kaizhi Lu, Jianteng Gu
YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma
Xin Zhang, Xuehai Wang, Ran Xu, Jianxiong Ji, Yangyang Xu, Mingzhi Han, Yuzhen Wei, Bin Huang, Anjing Chen, Qing Zhang, Wenjie Li, Jian Wang, Xingang Li, Chen Qiu
HLA alleles modulate EBV viral load in multiple sclerosis
Simone Agostini, Roberta Mancuso, Franca R. Guerini, Sandra D’Alfonso, Cristina Agliardi, Ambra Hernis, Milena Zanzottera, Nadia Barizzone, Maurizio A. Leone, Domenico Caputo, Marco Rovaris, Mario Clerici
Distinctive features of immunostaining and mutational load in primary pulmonary enteric adenocarcinoma: implications for differential diagnosis and immunotherapy
Ming Chen, Pu Liu, Feifei Yan, Suzhen Xu, Qi Jiang, Jingying Pan, Mengye He, Peng Shen
Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors
Michael F. Gowen, Keith M. Giles, Danny Simpson, Jeremy Tchack, Hua Zhou, Una Moran, Zarmeena Dawood, Anna C. Pavlick, Shaohui Hu, Melissa A. Wilson, Hua Zhong, Michelle Krogsgaard, Tomas Kirchhoff, Iman Osman
Association between serum S100A9 levels and liver necroinflammation in chronic hepatitis B
Rui Wu, Yuhong Zhang, Yu Xiang, Yishu Tang, Fang Cui, Ju Cao, Lan Zhou, Yan You, Liang Duan
Adolescent mental health education InSciEd Out: a case study of an alternative middle school population
Joanna Yang, Roberto Lopez Cervera, Susannah J. Tye, Stephen C. Ekker, Chris Pierret
An in vitro investigation of telocytes-educated macrophages: morphology, heterocellular junctions, apoptosis and invasion analysis
Xiao-Juan Jiang, Dragos Cretoiu, Zong-Ji Shen, Xiao-Jun Yang
Use of the tumor-infiltrating CD8 to FOXP3 lymphocyte ratio in predicting treatment responses to combination therapy with pertuzumab, trastuzumab, and docetaxel for advanced HER2-positive breast cancer
Koji Takada, Shinichiro Kashiwagi, Wataru Goto, Yuka Asano, Katsuyuki Takahashi, Tsutomu Takashima, Shuhei Tomita, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira
Prediction of treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer by analysis of immune checkpoint protein expression
Yuka Asano, Shinichiro Kashiwagi, Wataru Goto, Koji Takada, Katsuyuki Takahashi, Tamami Morisaki, Hisakazu Fujita, Tsutomu Takashima, Shuhei Tomita, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira
CD109 and squamous cell carcinoma
Ruixia Qi, Fengyun Dong, Qiang Liu, Yoshiki Murakumo, Ju Liu
Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
Seán Fitzgerald, Virginia Espina, Lance Liotta, Katherine M. Sheehan, Anthony O’Grady, Robert Cummins, Richard O’Kennedy, Elaine W. Kay, Gregor S. Kijanka
Association of genetic polymorphisms in genes involved in Ara-C and dNTP metabolism pathway with chemosensitivity and prognosis of adult acute myeloid leukemia (AML)
Ke-Wei Zhu, Peng Chen, Dao-Yu Zhang, Han Yan, Han Liu, Li-Na Cen, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao, Xiao-Ping Chen
Urinary miR-196a predicts disease progression in patients with chronic kidney disease
Changming Zhang, Shaoshan Liang, Shuiqin Cheng, Wei Li, Xia Wang, Chunxia Zheng, Caihong Zeng, Shaolin Shi, Lu Xie, Ke Zen, Zhihong Liu
Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention
Larisa H. Cavallari, Francesco Franchi, Fabiana Rollini, Latonya Been, Andrea Rivas, Malhar Agarwal, D. Max Smith, Kimberly Newsom, Yan Gong, Amanda R. Elsey, Petr Starostik, Julie A. Johnson, Dominick J. Angiolillo
Simultaneous VENTANA IHC and RT-PCR testing of ALK status in Chinese non-small cell lung cancer patients and response to crizotinib
Chun-wei Xu, Wen-xian Wang, Yan-ping Chen, Yu Chen, Wei Liu, Li-hua Zhong, Fang-fang Chen, Wu Zhuang, Zheng-bo Song, Xiao-hui Chen, Yun-jian Huang, Yan-fang Guan, Xin Yi, Tang-feng Lv, Wei-feng Zhu, Jian-ping Lu, Xiao-jiang Wang, Yi Shi, Xian-dong Lin, Gang Chen, Yong Song
Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade
Sara Valpione, Sandro Pasquali, Luca Giovanni Campana, Luisa Piccin, Simone Mocellin, Jacopo Pigozzo, Vanna Chiarion-Sileni
Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis
Yoshinobu Ikeno, Satoru Seo, Keiko Iwaisako, Tomoaki Yoh, Yuji Nakamoto, Hiroaki Fuji, Kojiro Taura, Hideaki Okajima, Toshimi Kaido, Shimon Sakaguchi, Shinji Uemoto
Cisplatin based therapy: the role of the mitogen activated protein kinase signaling pathway
Iman W. Achkar, Nabeel Abdulrahman, Hend Al-Sulaiti, Jensa Mariam Joseph, Shahab Uddin, Fatima Mraiche
Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection
Alice M. Richardson, Don P. Lewis, Badia Kita, Helen Ludlow, Nigel P. Groome, Mark P. Hedger, David M. de Kretser, Brett A. Lidbury
The physiological role of Motin family and its dysregulation in tumorigenesis
Tingting Huang, Yuhang Zhou, Jinglin Zhang, Alfred S. L. Cheng, Jun Yu, Ka Fai To, Wei Kang
Harnessing Qatar Biobank to understand type 2 diabetes and obesity in adult Qataris from the First Qatar Biobank Project
Ehsan Ullah, Raghvendra Mall, Reda Rawi, Naima Moustaid-Moussa, Adeel A. Butt, Halima Bensmail
The positive role of vitronectin in radiation induced lung toxicity: the in vitro and in vivo mechanism study
Tian-Le Shen, Mi-Na Liu, Qin Zhang, Wen Feng, Wen Yu, Xiao-Long Fu, Xu-Wei Cai
The Great Debate at “Melanoma Bridge”, Napoli, December 2nd, 2017
Paolo A. Ascierto, Corrado Caracò, Jeffrey E. Gershenwald, Omid Hamid, Merrick Ross, Ryan J. Sullivan, Igor Puzanov
Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation?
C. Tersigni, S. D’Ippolito, F. Di Nicuolo, R. Marana, V. Valenza, V. Masciullo, F. Scaldaferri, F. Malatacca, C. de Waure, A. Gasbarrini, G. Scambia, N. Di Simone
Recombinant mouse periostin ameliorates coronal sutures fusion in Twist1+/− mice
Shanshan Bai, Dong Li, Liang Xu, Huichuan Duan, Jie Yuan, Min Wei
Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease
Vasiliki Lygirou, Agnieszka Latosinska, Manousos Makridakis, William Mullen, Christian Delles, Joost P. Schanstra, Jerome Zoidakis, Burkert Pieske, Harald Mischak, Antonia Vlahou
Endoplasmic reticulum stress in perivascular adipose tissue promotes destabilization of atherosclerotic plaque by regulating GM-CSF paracrine
Ru Ying, Sheng-Wei Li, Jia-Yuan Chen, Hai-Feng Zhang, Ying Yang, Zhen-Jie Gu, Yang-Xin Chen, Jing-Feng Wang
Contribution of TLR4 signaling in intermittent hypoxia-mediated atherosclerosis progression
Xianqin Zeng, Rong Guo, Mei Dong, Julia Zheng, Huili Lin, Huixia Lu
Patient-derived xenograft models in musculoskeletal malignancies
Wan Lu, Tu Chao, Chen Ruiqi, Su Juan, Li Zhihong
CCL20 is up-regulated in non-alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading
Xin Chu, Qunyan Jin, Hui Chen, G. Craig Wood, Anthony Petrick, William Strodel, Jon Gabrielsen, Peter Benotti, Tooraj Mirshahi, David J. Carey, Christopher D. Still, Johanna K. DiStefano, Glenn S. Gerhard
MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus
Julia Slotta-Huspenina, Enken Drecoll, Marcus Feith, Daniel Habermehl, Stephanie Combs, Wilko Weichert, Marcus Bettstetter, Karen Becker, Rupert Langer
Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose
Michael P. O’Leary, Audrey H. Choi, Sang-In Kim, Shyambabu Chaurasiya, Jianming Lu, Anthony K. Park, Yanghee Woo, Susanne G. Warner, Yuman Fong, Nanhai G. Chen
Cardiopulmonary bypass reduces myocardial oxidative stress, inflammation and increases c-kit+CD45− cell population in newborns
Johannes Petersen, Andrey Kazakov, Michael Böhm, Hans-Joachim Schäfers, Ulrich Laufs, Hashim Abdul-Khaliq
The release of cardioprotective humoral factors after remote ischemic preconditioning in humans is age- and sex-dependent
André Heinen, Friederike Behmenburg, Aykut Aytulun, Maximilian Dierkes, Lea Zerbin, Wolfgang Kaisers, Maximilian Schaefer, Tanja Meyer-Treschan, Susanne Feit, Inge Bauer, Markus W. Hollmann, Ragnar Huhn
Effects of mesenchymal stem cells on solid tumor metastasis in experimental cancer models: a systematic review and meta-analysis
Jing-Huan Li, Wen-Shuai Fan, Mi-Mi Wang, Yan-Hong Wang, Zheng-Gang Ren
Postprandial increase in serum CA125 as a surrogate biomarker for early diagnosis of ovarian cancer
Zhuowei Gu, Yifeng He, Yue Zhang, Mo Chen, Keqi Song, Yuting Huang, Qing Li, Wen Di
A validation study of crescents in predicting ESRD in patients with IgA nephropathy
Xiaoyan Zhang, Sufang Shi, Yan Ouyang, Meng Yang, Manman Shi, Xiaoxia Pan, Jicheng Lv, Zhaohui Wang, Hong Ren, Pingyan Shen, Weiming Wang, Hong Zhang, Jingyuan Xie, Nan Chen
Establishment and validation of a predictive nomogram model for non-small cell lung cancer patients with chronic hepatitis B viral infection
Shulin Chen, Yanzhen Lai, Zhengqiang He, Jianpei Li, Xia He, Rui Shen, Qiuying Ding, Hao Chen, Songguo Peng, Wanli Liu
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury
Yu Gu, Fei Huang, Yanling Wang, Chaojin Chen, Shan Wu, Shaoli Zhou, Ziqing Hei, Dongdong Yuan
Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer
Pascale Kündig, Charlotte Giesen, Hartland Jackson, Bernd Bodenmiller, Bärbel Papassotirolopus, Sandra Nicole Freiberger, Catharine Aquino, Lennart Opitz, Zsuzsanna Varga
Open innovation and external sources of innovation. An opportunity to fuel the R&D pipeline and enhance decision making?
Alexander Schuhmacher, Oliver Gassmann, Nigel McCracken, Markus Hinder
Gastric cancer vaccines synthesized using a TLR7 agonist and their synergistic antitumor effects with 5-fluorouracil
Xiaodong Wang, Yu Liu, Yuwen Diao, Ningning Gao, Yanyan Wan, Jingjing Zhong, Huali Zheng, Zhulin Wang, Guangyi Jin
The role of HIV Tat protein in HIV-related cardiovascular diseases
Yanan Jiang, Lu Chai, Moyondafoluwa Blessing Fasae, Yunlong Bai
Correction to: Gamma-delta (γδ) T cells: friend or foe in cancer development?
Yijing Zhao, Chao Niu, Jiuwei Cui
Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
Zhaofeng Jia, Qisong Liu, Yujie Liang, Xingfu Li, Xiao Xu, Kan Ouyang, Jianyi Xiong, Daping Wang, Li Duan
Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts
Regina Gary, Michael Aigner, Stephanie Moi, Stefanie Schaffer, Anja Gottmann, Stefanie Maas, Robert Zimmermann, Jürgen Zingsem, Julian Strobel, Andreas Mackensen, Josef Mautner, Andreas Moosmann, Armin Gerbitz
Nonclinical and clinical pharmacological characterization of the potent and selective cathepsin K inhibitor MIV-711
Erik Lindström, Biljana Rizoska, Ian Henderson, Ylva Terelius, Markus Jerling, Charlotte Edenius, Urszula Grabowska
Clinical performance of stem cell therapy in patients with acute-on-chronic liver failure: a systematic review and meta-analysis
Ran Xue, Qinghua Meng, Jinling Dong, Juan Li, Qinwei Yao, Yueke Zhu, Hongwei Yu
Comprehensive and integrative analysis identifies microRNA-106 as a novel non-invasive biomarker for detection of gastric cancer
Qiliang Peng, Yi Shen, Kaisu Lin, Li Zou, Yuntian Shen, Yaqun Zhu
Correction to: MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus
Julia Slotta-Huspenina, Enken Drecoll, Marcus Feith, Daniel Habermehl, Stephanie E. Combs, Wilko Weichert, Marcus Bettstetter, Karen Becker, Rupert Langer
Observational study of coagulation activation in early breast cancer: development of a prognostic model based on data from the real world setting
Chiara Mandoj, Laura Pizzuti, Domenico Sergi, Isabella Sperduti, Marco Mazzotta, Luigi Di Lauro, Antonella Amodio, Silvia Carpano, Anna Di Benedetto, Claudio Botti, Francesca Ferranti, Anna Antenucci, Maria Gabriella D’Alessandro, Paolo Marchetti, Silverio Tomao, Giuseppe Sanguineti, Antonio Giordano, Marcello Maugeri-Saccà, Gennaro Ciliberto, Laura Conti, Patrizia Vici, Maddalena Barba
Evidence for a hyper-reductive redox in a sub-set of heart failure patients
Thiagarajan Sairam, Amit N. Patel, Meenu Subrahmanian, Rajendiran Gopalan, Steven M. Pogwizd, Sudha Ramalingam, Ramalingam Sankaran, Namakkal Soorapan Rajasekaran
Identification of micro-RNA expression profile related to recurrence in women with ESMO low-risk endometrial cancer
Tiphaine de Foucher, Maria Sbeih, Jenifer Uzan, Sofiane Bendifallah, Marine Lefevre, Nathalie Chabbert-Buffet, Selim Aractingi, Catherine Uzan, Issam Abd Alsalam, Rana Mitri, Romain H. Fontaine, Emile Daraï, Bassam Haddad, Céline Méhats, Marcos Ballester, Geoffroy Canlorbe, Cyril Touboul
CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma
Chun Xu, Xian Lu, Wei Liu, Anxian Chen, Gang Meng, Hailin Zhang, Binghua Li, Yonghui Zhang, Junhua Wu, Jiwu Wei
The homing of bone marrow stem cells is differentially activated in ischemic and valvular heart diseases and influenced by beta-blockers
Melissa Kristocheck, Lucinara D. Dias, Carine Ghem, Bruna Eibel, Renato A. K. Kalil, Melissa M. Markoski
Biomarker microRNAs for prostate cancer metastasis: screened with a network vulnerability analysis model
Yuxin Lin, Feifei Chen, Li Shen, Xiaoyu Tang, Cui Du, Zhandong Sun, Huijie Ding, Jiajia Chen, Bairong Shen
Dysregulation of miR-200s clusters as potential prognostic biomarkers in acute myeloid leukemia
Jing-dong Zhou, Liu-chao Zhang, Ting-juan Zhang, Yu Gu, De-hong Wu, Wei Zhang, Ji-chun Ma, Xiang-mei Wen, Hong Guo, Jiang Lin, Jun Qian
Biobanks and scientists: supply and demand
Angelo Virgilio Paradiso, Maria Grazia Daidone, Vincenzo Canzonieri, Alfredo Zito
Endothelial progenitor cells improve the therapeutic effect of mesenchymal stem cell sheets on irradiated bone defect repair in a rat model
Huan Liu, Yang Jiao, Wei Zhou, Shizhu Bai, Zhihong Feng, Yan Dong, Qian Liu, Xiaoke Feng, Yimin Zhao
Establishment of lung cancer patient-derived xenograft models and primary cell lines for lung cancer study
Yanan Jiang, Jimin Zhao, Yi Zhang, Ke Li, Tiepeng Li, Xinhuan Chen, Simin Zhao, Song Zhao, Kangdong Liu, Ziming Dong
Wedge-shaped microfluidic chip for circulating tumor cells isolation and its clinical significance in gastric cancer
Chaogang Yang, Nangang Zhang, Shuyi Wang, Dongdong Shi, Chunxiao Zhang, Kan Liu, Bin Xiong
Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation
S. Castellani, A. Trapani, A. Spagnoletta, L. di Toma, T. Magrone, S. Di Gioia, D. Mandracchia, G. Trapani, E. Jirillo, M. Conese
Abnormalities of hair structure and skin histology derived from CRISPR/Cas9-based knockout of phospholipase C-delta 1 in mice
Yu-Min Liu, Wei Liu, Jun-Shuang Jia, Bang-Zhu Chen, Heng-Wei Chen, Yu Liu, Ya-Nan Bie, Peng Gu, Yan Sun, Dong Xiao, Wei-Wang Gu
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
Linda M. Liau, Keyoumars Ashkan, David D. Tran, Jian L. Campian, John E. Trusheim, Charles S. Cobbs, Jason A. Heth, Michael Salacz, Sarah Taylor, Stacy D. D’Andre, Fabio M. Iwamoto, Edward J. Dropcho, Yaron A. Moshel, Kevin A. Walter, Clement P. Pillainayagam, Robert Aiken, Rekha Chaudhary, Samuel A. Goldlust, Daniela A. Bota, Paul Duic, Jai Grewal, Heinrich Elinzano, Steven A. Toms, Kevin O. Lillehei, Tom Mikkelsen, Tobias Walbert, Steven R. Abram, Andrew J. Brenner, Steven Brem, Matthew G. Ewend, Simon Khagi, Jana Portnow, Lyndon J. Kim, William G. Loudon, Reid C. Thompson, David E. Avigan, Karen L. Fink, Francois J. Geoffroy, Scott Lindhorst, Jose Lutzky, Andrew E. Sloan, Gabriele Schackert, Dietmar Krex, Hans-Jorg Meisel, Julian Wu, Raphael P. Davis, Christopher Duma, Arnold B. Etame, David Mathieu, Santosh Kesari, David Piccioni, Manfred Westphal, David S. Baskin, Pamela Z. New, Michel Lacroix, Sven-Axel May, Timothy J. Pluard, Victor Tse, Richard M. Green, John L. Villano, Michael Pearlman, Kevin Petrecca, Michael Schulder, Lynne P. Taylor, Anthony E. Maida, Robert M. Prins, Timothy F. Cloughesy, Paul Mulholland, Marnix L. Bosch
Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF
Krzysztof Laudanski, Mateusz Zawadka, Jacek Polosak, Jaymin Modi, Matthew DiMeglio, Jacob Gutsche, Wilson Y. Szeto, Monika Puzianowska-Kuznicka
Regulatory γδ T cells induced by G-CSF participate in acute graft-versus-host disease regulation in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation
Li Xuan, Xiuli Wu, Dan Qiu, Li Gao, Hui Liu, Zhiping Fan, Fen Huang, Zhenyi Jin, Jing Sun, Yangqiu Li, Qifa Liu
Distinct mutations with different inheritance mode caused similar retinal dystrophies in one family: a demonstration of the importance of genetic annotations in complicated pedigrees
Xue Chen, Xunlun Sheng, Yani Liu, Zili Li, Xiantao Sun, Chao Jiang, Rui Qi, Shiqin Yuan, Xuhui Wang, Ge Zhou, Yanyan Zhen, Ping Xie, Qinghuai Liu, Biao Yan, Chen Zhao
Role of p53/miR-155-5p/sirt1 loop in renal tubular injury of diabetic kidney disease
Yue Wang, Zong-ji Zheng, Yi-jie Jia, Yan-lin Yang, Yao-ming Xue
Immunotherapeutic interventions of Triple Negative Breast Cancer
Zehuan Li, Yiran Qiu, Weiqi Lu, Ying Jiang, Jin Wang
Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime
Solange Moll, Yukari Yasui, Ahmed Abed, Takeshi Murata, Hideaki Shimada, Akira Maeda, Naoshi Fukushima, Masakazu Kanamori, Sabine Uhles, Laura Badi, Thomas Cagarelli, Ivan Formentini, Faye Drawnel, Guy Georges, Tobias Bergauer, Rodolfo Gasser, R. Daniel Bonfil, Rafael Fridman, Hans Richter, Juergen Funk, Marcus J. Moeller, Christos Chatziantoniou, Marco Prunotto
Expected advances in human fertility treatments and their likely translational consequences
Norbert Gleicher
Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway
Yi Pan, Siu Tim Cheung, Joanna Hung Man Tong, Ka Yee Tin, Wei Kang, Raymond Wai Ming Lung, Feng Wu, Hui Li, Simon Siu Man Ng, Tony Wing Chung Mak, Ka Fai To, Anthony Wing Hung Chan
Multimodal characterization of the semantic N400 response within a rapid evaluation brain vital sign framework
Sujoy Ghosh Hajra, Careesa C. Liu, Xiaowei Song, Shaun D. Fickling, Teresa P. L. Cheung, Ryan C. N. D’Arcy
Decrease of the DNA methylation levels of the ADRB3 gene in leukocytes is related with serum folate in eutrophic adults
Yohanna de Oliveira, Raquel Patrícia Ataíde Lima, Rafaella Cristhine Pordeus Luna, Mussara Gomes Cavalcanti Alves Monteiro, Cássia Surama Oliveira da Silva, Rayner Anderson Ferreira do Nascimento, Keylha Querino de Farias Lima, Ana Hermínia Andrade e Silva, Flávia Emília Leite de Lima Ferreira, Rodrigo Pinheiro de Toledo Vianna, Ronei Marcos de Moraes, Naila Francis Paulo de Oliveira, Aléssio Tony Cavalcanti de Almeida, Alexandre Sérgio Silva, Alcides da Silva Diniz, Maria José de Carvalho Costa, Maria da Conceição Rodrigues Gonçalves
Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults
Christine M. D. Lingblom, Sangeeta Kowli, Nithya Swaminathan, Holden T. Maecker, Stacie L. Lambert
In silico identification of drug target pathways in breast cancer subtypes using pathway cross-talk inhibition
Claudia Cava, Gloria Bertoli, Isabella Castiglioni
Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice
Jia Cao, Yanyong Xu, Feifei Li, Liang Shang, Daping Fan, Hong Yu
Discriminating phenotypic signatures identified for tocilizumab, adalimumab, and tofacitinib monotherapy and their combinations with methotrexate
Alison O’Mahony, Markus R. John, Hannah Cho, Misato Hashizume, Ernest H. Choy
A strategy for designing voriconazole dosage regimens to prevent invasive pulmonary aspergillosis based on a cellular pharmacokinetics/pharmacodynamics model
Taotao Wang, Tao Zhang, Ti Meng, Ying Li, Lu Chen, Qianting Yang, Haiyan Dong, Jin’e Lei, Limei Chen, Yalin Dong
Family specific genetic predisposition to breast cancer: results from Tunisian whole exome sequenced breast cancer cases
Yosr Hamdi, Maroua Boujemaa, Mariem Ben Rekaya, Cherif Ben Hamda, Najah Mighri, Houda El Benna, Nesrine Mejri, Soumaya Labidi, Nouha Daoud, Chokri Naouali, Olfa Messaoud, Mariem Chargui, Kais Ghedira, Mohamed Samir Boubaker, Ridha Mrad, Hamouda Boussen, Sonia Abdelhak
Microfibrillar-associated protein 4 variation in symptomatic peripheral artery disease
Line Ea Hemstra, Anders Schlosser, Jes Sanddal Lindholt, Grith L. Sorensen
Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2 G2019S -Parkinson’s disease
Diana Luz Juárez-Flores, Ingrid González-Casacuberta, Mario Ezquerra, María Bañó, Francesc Carmona-Pontaque, Marc Catalán-García, Mariona Guitart-Mampel, Juan José Rivero, Ester Tobias, Jose Cesar Milisenda, Eduard Tolosa, Maria Jose Marti, Ruben Fernández-Santiago, Francesc Cardellach, Constanza Morén, Glòria Garrabou
MiR-1-3p that correlates with left ventricular function of HCM can serve as a potential target and differentiate HCM from DCM
Mengmeng Li, Xiao Chen, Liang Chen, Kai Chen, Jianye Zhou, Jiangping Song
Clinicopathologic implication of microRNA-197 in diffuse large B cell lymphoma
Jeong Mi Yang, Ji-Young Jang, Yoon Kyung Jeon, Jin Ho Paik
Identification of a low risk population for parametrial invasion in patients with early-stage cervical cancer
Yohann Dabi, Claire Willecocq, Marcos Ballester, Xavier Carcopino, Sofiane Bendifallah, Lobna Ouldamer, Vincent Lavoue, Geoffroy Canlorbe, Emilie Raimond, Charles Coutant, Olivier Graesslin, Pierre Collinet, Alexandre Bricou, Cyrille Huchon, Emile Daraï, Bassam Haddad, Cyril Touboul
Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway
Tianxiao Gong, Liuqing Cui, Haili Wang, Haoxun Wang, Na Han
Serum IFN-γ levels predict the therapeutic effect of mesenchymal stem cell transplantation in active rheumatoid arthritis
Yi Yang, Xiao He, Rongseng Zhao, Wei Guo, Ming Zhu, Wei Xing, Dongpo Jiang, Chongyang Liu, Xiang Xu
Prediction of hepatic necroinflammatory activity in patients with chronic hepatitis B by a simple noninvasive model
Fei-Fei Shen, Yan Wang, Yi-Fei Wang, Rui-Dan Zheng, Jian-Chun Xian, Jun-Ping Shi, Ying Qu, Yu-Wei Dong, Ming-Yi Xu, Lun-Gen Lu
3D printing individualized heel cup for improving the self-reported pain of plantar fasciitis
Lan Li, Longfei Yang, Fei Yu, Jianping Shi, Liya Zhu, Xianfeng Yang, Huajian Teng, Xingsong Wang, Qing Jiang
Polyethylene glycol-conjugated HER2-targeted peptides as a nuclear imaging probe for HER2-overexpressed gastric cancer detection in vivo
Siao-Syun Guan, Cheng-Tien Wu, Chen-Yuan Chiu, Tsai-Yueh Luo, Jeng-Yih Wu, Tse-Zung Liao, Shing-Hwa Liu
CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E-cadherin
Jingjing Xu, Jun Zhou, Hanjue Dai, Fei Liu, Wenjing Li, Wenjuan Wang, Feng Guo
Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia
Sharon Wu, Yang Du, John Beckford, Houda Alachkar
A prospective study on the changes and clinical significance of pre-operative and post-operative circulating tumor cells in resectable gastric cancer
Qiyue Zhang, Fei Shan, Ziyu Li, Jing Gao, Yilin Li, Lin Shen, Jiafu Ji, Ming Lu
Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients
Serena De Matteis, Chiara Molinari, Giulia Abbati, Tania Rossi, Roberta Napolitano, Martina Ghetti, Andrea Ghelli Luserna Di Rorà, Gerardo Musuraca, Alessandro Lucchesi, Gian Matteo Rigolin, Antonio Cuneo, Daniele Calistri, Pier Paolo Fattori, Massimiliano Bonafè, Giovanni Martinelli
Association of viral hepatitis and bipolar disorder: a nationwide population-based study
Lee-Won Chong, Chih-Chao Hsu, Chang-Yin Lee, Ruey-Hwang Chou, Cheng-Li Lin, Kuang-Hsi Chang, Yi-Chao Hsu
Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials
H. Chopra, C. Liao, C. F. Zhang, E. H. N. Pow
Triglyceride profiling in adipose tissues from obese insulin sensitive, insulin resistant and type 2 diabetes mellitus individuals
Haya Al-Sulaiti, Ilhame Diboun, Sameem Banu, Mohamed Al-Emadi, Parvaneh Amani, Thomas M. Harvey, Alex S. Dömling, Aishah Latiff, Mohamed A. Elrayess
Efficacy and safety of the artificial pancreas in the paediatric population with type 1 diabetes
Susanna Esposito, Elisa Santi, Giulia Mancini, Francesco Rogari, Giorgia Tascini, Giada Toni, Alberto Argentiero, Maria Giulia Berioli
Identification of anti-SF3B1 autoantibody as a diagnostic marker in patients with hepatocellular carcinoma
Hai-Min Hwang, Chang-Kyu Heo, Hye Jung Lee, Sang-Seob Kwak, Won-Hee Lim, Jong-Shin Yoo, Dae-Yuel Yu, Kook Jin Lim, Jeong-Yoon Kim, Eun-Wie Cho
Obstacles to successful treatment of hepatitis C in uninsured patients from a minority population
Alexandra DeBose-Scarlett, Raymond Balise, Deukwoo Kwon, Susan Vadaparampil, Steven Xi Chen, Eugene R. Schiff, Gladys Patricia Ayala, Emmanuel Thomas
Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
Linda M. Liau, Keyoumars Ashkan, David D. Tran, Jian L. Campian, John E. Trusheim, Charles S. Cobbs, Jason A. Heth, Michael Salacz, Sarah Taylor, Stacy D. D’Andre, Fabio M. Iwamoto, Edward J. Dropcho, Yaron A. Moshel, Kevin A. Walter, Clement P. Pillainayagam, Robert Aiken, Rekha Chaudhary, Samuel A. Goldlust, Daniela A. Bota, Paul Duic, Jai Grewal, Heinrich Elinzano, Steven A. Toms, Kevin O. Lillehei, Tom Mikkelsen, Tobias Walbert, Steven R. Abram, Andrew J. Brenner, Steven Brem, Matthew G. Ewend, Simon Khagi, Jana Portnow, Lyndon J. Kim, William G. Loudon, Reid C. Thompson, David E. Avigan, Karen L. Fink, Francois J. Geoffroy, Scott Lindhorst, Jose Lutzky, Andrew E. Sloan, Gabriele Schackert, Dietmar Krex, Hans-Jorg Meisel, Julian Wu, Raphael P. Davis, Christopher Duma, Arnold B. Etame, David Mathieu, Santosh Kesari, David Piccioni, Manfred Westphal, David S. Baskin, Pamela Z. New, Michel Lacroix, Sven-Axel May, Timothy J. Pluard, Victor Tse, Richard M. Green, John L. Villano, Michael Pearlman, Kevin Petrecca, Michael Schulder, Lynne P. Taylor, Anthony E. Maida, Robert M. Prins, Timothy F. Cloughesy, Paul Mulholland, Marnix L. Bosch
Correction to: Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer
Pascale Kündig, Charlotte Giesen, Hartland Jackson, Bernd Bodenmiller, Bärbel Papassotirolopus, Sandra Nicole Freiberger, Catharine Aquino, Lennart Opitz, Zsuzsanna Varga
Computer-aided prediction of antigen presenting cell modulators for designing peptide-based vaccine adjuvants
Gandharva Nagpal, Kumardeep Chaudhary, Piyush Agrawal, Gajendra P. S. Raghava
Epstein–Barr virus- and cytomegalovirus-specific immune response in patients with brain cancer
Zhenjiang Liu, Thomas Poiret, Qingda Meng, Martin Rao, Anna von Landenberg, Esther Schoutrop, Davide Valentini, Ernest Dodoo, Inti Peredo-Harvey, Markus Maeurer
Nuclear Klf4 accumulation is associated with cetuximab drug-resistance and predicts poor prognosis of nasopharyngeal carcinoma
Xiqing Li, Zunlan Zhao, Shijiang Yi, Lei Ma, Ming Li, Mingyue Liu, Yaping Zhang, Guangzhi Liu
Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma
Janet Retseck, Alexis Nasr, Yan Lin, Huang Lin, Prateek Mendiratta, Lisa H. Butterfield, Ahmad A. Tarhini
Genetic characterisation of molecular targets in carcinoma of unknown primary
B. Clynick, B. Dessauvagie, G. Sterrett, N. T. Harvey, R. J. N. Allcock, C. Saunders, W. Erber, K. Meehan
Association of the peripheral blood levels of circulating microRNAs with both recurrent miscarriage and the outcomes of embryo transfer in an in vitro fertilization process
Qian Yang, Wen-Wen Gu, Yan Gu, Na-Na Yan, Yan-Yan Mao, Xing-Xing Zhen, Jian-Mei Wang, Jing Yang, Hui-Juan Shi, Xuan Zhang, Jian Wang
A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients
Yanqiong Zhang, Hailong Wang, Xia Mao, Qiuyan Guo, Weijie Li, Xiaoyue Wang, Guangyao Li, Na Lin
Serum and thyroid tissue level of let-7b and their correlation with TRAb in Graves’ disease
Xinxin Chen, Fengjiao Huang, Yicheng Qi, Mengxi Zhou, Qinglei Yin, Ying Peng, Yulin Zhou, Guang Ning, Shu Wang
Gene expression pattern of TCR repertoire and alteration expression of IL-17A gene of γδ T cells in patients with acute myocardial infarction
Xiao-ming Chen, Tao Zhang, Dan Qiu, Jian-yi Feng, Zhen-yi Jin, Qiang Luo, Xin-yu Wang, Xiu-li Wu
Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer
Prakash C. Thakur, Jennifer L. Miller-Ocuin, Khanh Nguyen, Rina Matsuda, Aatur D. Singhi, Herbert J. Zeh, Nathan Bahary
The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs
Andrew J. Pellatt, Lila E. Mullany, Jennifer S. Herrick, Lori C. Sakoda, Roger K. Wolff, Wade S. Samowitz, Martha L. Slattery
The dimensionality of fatigue in Parkinson’s disease
Raymond Chong, Lauren Albor, Chandramohan Wakade, John Morgan
Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model
Xue-Mei Zhang, Jiao Ma, Yang Sun, Bing-Qian Yu, Zhuo-Min Jiao, Duo Wang, Mei-Yu Yu, Jin-Yue Li, Jin Fu
Detecting germline BAP1 mutations in patients with peritoneal mesothelioma: benefits to patient and family members
Muaiad Kittaneh, Charles Berkelhammer
Comparison of immunological characteristics between paired mismatch repair-proficient and -deficient colorectal cancer patients
Shou-Sheng Liu, Yuan-Zhong Yang, Chang Jiang, Qi Quan, Qian-Kun Xie, Xiao-Pai Wang, Wen-Zhuo He, Yu-Ming Rong, Ping Chen, Qiong Yang, Lin Yang, Bei Zhang, Xiao-Jun Xia, Peng-Fei Kong, Liang-Ping Xia
A Phase 1 trial of autologous monocytes stimulated ex vivo with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for intra-peritoneal administration in recurrent ovarian cancer
Daniel S. Green, Ana T. Nunes, Virginia David-Ocampo, Irene B. Ekwede, Nicole D. Houston, Steven L. Highfill, Hanh Khuu, David F. Stroncek, Seth M. Steinberg, Kathryn C. Zoon, Christina M. Annunziata
Influence of UGT1A1 polymorphisms on the outcome of acute myeloid leukemia patients treated with cytarabine-base regimens
Peng Chen, Ke-Wei Zhu, Dao-Yu Zhang, Han Yan, Han Liu, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao, Jing Yang, Xiao-Ping Chen
PBMC fixation and processing for Chromium single-cell RNA sequencing
Jinguo Chen, Foo Cheung, Rongye Shi, Huizhi Zhou, Wenrui Lu, Julián Candia, Yuri Kotliarov, Katie R. Stagliano, John S. Tsang
Platelet storage induces accelerated desialylation of platelets and increases hepatic thrombopoietin production
Jooyoung Cho, Hyunkyung Kim, Jaewoo Song, June-Won Cheong, Jeong Won Shin, Woo Ick Yang, Hyun Ok Kim
A clarion call to the community of current and potential journal reviewers
Michael N. Liebman, Franco Marincola
Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis
Qinrui Han, Ye Ma, Hao Wang, Yu Dai, Chunhui Chen, Yawei Liu, Linlin Jing, Xuegang Sun
GC/MS-based urine metabolomics analysis of renal allograft recipients with acute rejection
Long Zheng, Jina Wang, Wenjun Gao, Chao Hu, Shuo Wang, Ruiming Rong, Yinlong Guo, Tongyu Zhu, Dong Zhu
Novel distance-progesterone-combined selection approach improves human sperm quality
Kun Li, Rui Li, Ya Ni, Peibei Sun, Ye Liu, Dan Zhang, Hefeng Huang
In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
Marta Starczak, Ewelina Zarakowska, Martyna Modrzejewska, Tomasz Dziaman, Anna Szpila, Kinga Linowiecka, Jolanta Guz, Justyna Szpotan, Maciej Gawronski, Anna Labejszo, Ariel Liebert, Zbigniew Banaszkiewicz, Maria Klopocka, Marek Foksinski, Daniel Gackowski, Ryszard Olinski
Identification of an early diagnostic biomarker of lung adenocarcinoma based on co-expression similarity and construction of a diagnostic model
Zhirui Fan, Wenhua Xue, Lifeng Li, Chaoqi Zhang, Jingli Lu, Yunkai Zhai, Zhenhe Suo, Jie Zhao
Screening and identification of a six-cytokine biosignature for detecting TB infection and discriminating active from latent TB
Sen Wang, Yang Li, Yaojie Shen, Jing Wu, Yan Gao, Shu Zhang, Lingyun Shao, Jialin Jin, Ying Zhang, Wenhong Zhang
Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)
Paolo A. Ascierto, Igor Puzanov, Sanjiv S. Agarwala, Carlo Bifulco, Gerardo Botti, Corrado Caracò, Gennaro Ciliberto, Michael A. Davies, Reinhard Dummer, Soldano Ferrone, Thomas F. Gajewski, Claus Garbe, Jason J. Luke, Francesco M. Marincola, Giuseppe Masucci, Janice M. Mehnert, Nicola Mozzillo, Giuseppe Palmieri, Michael A. Postow, Stephen P. Schoenberger, Ena Wang, Magdalena Thurin
Numerical simulation of patient-specific endovascular stenting and coiling for intracranial aneurysm surgical planning
Xiaochang Leng, Yang Wang, Jing Xu, Yeqing Jiang, Xiaolong Zhang, Jianping Xiang
Dexmedetomidine attenuates spinal cord ischemia–reperfusion injury through both anti-inflammation and anti-apoptosis mechanisms in rabbits
Zhixiang Sun, Tianyun Zhao, Shaojun Lv, Ying Gao, Joe Masters, Hao Weng
Comprehensive identification of immune-associated biomarkers based on network and mRNA expression patterns in membranous glomerulonephritis
Chengwei Zhang, Lei Leng, Xiaoming Zhang, Yao Zhao, Zhaozheng Li
The new era of precision population health: insights for the All of Us Research Program and beyond
Courtney R. Lyles, Mitchell R. Lunn, Juno Obedin-Maliver, Kirsten Bibbins-Domingo
Fibroblasts as a practical alternative to mesenchymal stem cells
Thomas E. Ichim, Pete O’Heeron, Santosh Kesari
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II)
José María Lamo-Espinosa, Gonzalo Mora, Juan F. Blanco, Froilán Granero-Moltó, Jorge María Núñez-Córdoba, Silvia López-Elío, Enrique Andreu, Fermín Sánchez-Guijo, José Dámaso Aquerreta, José María Bondía, Andrés Valentí-Azcárate, María del Consuelo del Cañizo, Eva María Villarón, Juan Ramón Valentí-Nin, Felipe Prósper
Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis
Marianne Engström, Kaja Eriksson, Linkiat Lee, Monika Hermansson, Anders Johansson, Anthony P. Nicholas, Natalija Gerasimcik, Karin Lundberg, Lars Klareskog, Anca Irinel Catrina, Tülay Yucel-Lindberg
MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits
Erik Taylor, Nasi Huang, Jacob Bodde, Andrew Ellison, Ronald Killiany, Markus Michael Bachschmid, James Hamilton
Regulatory network of circRNA–miRNA–mRNA contributes to the histological classification and disease progression in gastric cancer
Jia Cheng, Huiqin Zhuo, Mao Xu, Linpei Wang, Hao Xu, Jigui Peng, Jingjing Hou, Lingyun Lin, Jianchun Cai
Improving knowledge on the activation of bone marrow fibroblasts in MGUS and MM disease through the automatic extraction of genes via a nonnegative matrix factorization approach on gene expression profiles
Angelina Boccarelli, Flavia Esposito, Mauro Coluccia, Maria Antonia Frassanito, Angelo Vacca, Nicoletta Del Buono
The role of miR-29c/B7-H3 axis in children with allergic asthma
Xinxing Zhang, Xin Zhao, Huiming Sun, Yongdong Yan, Li Huang, Wenjin Gu, Wujun Jiang, Yuqing Wang, Canhong Zhu, Wei Ji, Chuangli Hao, Zhengrong Chen
Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC?
Andrea Botticelli, Bruna Cerbelli, Luana Lionetto, Ilaria Zizzari, Massimiliano Salati, Annalinda Pisano, Mazzuca Federica, Maurizio Simmaco, Marianna Nuti, Paolo Marchetti
A circRNA–miRNA–mRNA network identification for exploring underlying pathogenesis and therapy strategy of hepatocellular carcinoma
Dan-dan Xiong, Yi-wu Dang, Peng Lin, Dong-yue Wen, Rong-quan He, Dian-zhong Luo, Zhen-bo Feng, Gang Chen
HBV infection increases the risk of macular degeneration: the roles of HBx-mediated sensitization of retinal pigment epithelial cells to UV and blue light irradiation
Ruey-Hwang Chou, Chang-Yin Lee, Lee-Won Chong, Kuang-Hsi Chang, Cheng-Li Lin, Ke-Sin Yan, Chingfu Tsou, Yi-Chao Hsu
Comparing atmospheric and hypoxic cultured mesenchymal stem cell transcriptome: implication for stem cell therapies targeting intervertebral discs
C. Elabd, T. E. Ichim, K. Miller, A. Anneling, V. Grinstein, V. Vargas, F. J. Silva
Protocol for serum exosomal miRNAs analysis in prostate cancer patients treated with radiotherapy
Bijaya Malla, Daniel M. Aebersold, Alan Dal Pra
Cord blood leptin and insulin levels in association with mitochondrial DNA content
Annette Vriens, Michelle Plusquin, Willy Baeyens, Liesbeth Bruckers, Elly Den Hond, Ilse Loots, Vera Nelen, Greet Schoeters, Bram G. Janssen, Tim S. Nawrot
Lactobacillus salivarius reverse antibiotic-induced lung defense impairment in a ventilator model
Tzyy-Bin Tsay, Ming-Chieh Yang, Wan-Hsuan Chang, Pei-Hsuan Chen, Lee-Wei Chen
Enhanced effect of checkpoint inhibitors when given after or together with IMM-101: significant responses in four advanced melanoma patients with no additional major toxicity
Angus G. Dalgleish, Satvinder Mudan, Alberto Fusi
Urinary exosome miR-146a is a potential marker of albuminuria in essential hypertension
Javier Perez-Hernandez, Dolores Olivares, Maria J. Forner, Ana Ortega, Elena Solaz, Fernando Martinez, Felipe J. Chaves, Josep Redon, Raquel Cortes
YKL-40 is highly expressed in the epicardial adipose tissue of patients with atrial fibrillation and associated with atrial fibrosis
Qing Wang, Hua Shen, Jie Min, Yang Gao, Kai Liu, Wang Xi, Jie Yang, Liang Yin, Jibin Xu, Jian Xiao, Zhinong Wang
Blood pressure components and incident cardiovascular disease and mortality events among Iranian adults with chronic kidney disease during over a decade long follow-up: a prospective cohort study
Ashkan Hashemi, Sormeh Nourbakhsh, Samaneh Asgari, Mohammadhassan Mirbolouk, Fereidoun Azizi, Farzad Hadaegh
The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome
Chin-An Yang, Sandra Bauer, Yu-Chen Ho, Franziska Sotzny, Jan-Gowth Chang, Carmen Scheibenbogen
NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome
Luiza Handschuh, Pawel Wojciechowski, Maciej Kazmierczak, Malgorzata Marcinkowska-Swojak, Magdalena Luczak, Krzysztof Lewandowski, Mieczyslaw Komarnicki, Jacek Blazewicz, Marek Figlerowicz, Piotr Kozlowski
RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung injury in mice
Jingxian Chen, Shuang Wang, Rong Fu, Mianjing Zhou, Tengyue Zhang, Wenxu Pan, Niansheng Yang, Yuefang Huang
Clinical significance of hyaluronan levels and its pro-osteogenic effect on mesenchymal stromal cells in myelodysplastic syndromes
Cheng-Ming Fei, Juan Guo, You-Shan Zhao, Si-Da Zhao, Qing-Qing Zhen, Lei Shi, Xiao Li, Chun-Kang Chang
The changes of immunoglobulin G N-glycosylation in blood lipids and dyslipidaemia
Di Liu, Xi Chu, Hao Wang, Jing Dong, Si-Qi Ge, Zhong-Yao Zhao, Hong-Li Peng, Ming Sun, Li-Juan Wu, Man-Shu Song, Xiu-Hua Guo, Qun Meng, You-Xin Wang, Gordan Lauc, Wei Wang
Large-scale in silico identification of drugs exerting sex-specific effects in the heart
Changting Cui, Chuanbo Huang, Kejia Liu, Guoheng Xu, Jichun Yang, Yong Zhou, Yingmei Feng, Georgios Kararigas, Bin Geng, Qinghua Cui
Cytokines induced killer cells produced in good manufacturing practices conditions: identification of the most advantageous and safest expansion method in terms of viability, cellular growth and identity
Sara Castiglia, Aloe Adamini, Deborah Rustichelli, Laura Castello, Katia Mareschi, Giuseppe Pinnetta, Marco Leone, Alessandra Mandese, Ivana Ferrero, Giulia Mesiano, Franca Fagioli
Improved CD4 T cell profile in HIV-infected subjects on maraviroc-containing therapy is associated with better responsiveness to HBV vaccination
Inés Herrero-Fernández, Isaac Rosado-Sánchez, Miguel Genebat, Laura Tarancón-Díez, María Mar Rodríguez-Méndez, María Mar Pozo-Balado, Carmen Lozano, Ezequiel Ruiz-Mateos, Manuel Leal, Yolanda M. Pacheco
Invasive non-typhoidal Salmonella in sickle cell disease in Africa: is increased gut permeability the missing link?
Seah H. Lim, Barbara A. Methé, Bettina M. Knoll, Alison Morris, Stephen K. Obaro
Acute effects of different resistance training loads on cardiac autonomic modulation in hypertensive postmenopausal women
Arthur F. Vale, Juliana A. Carneiro, Paulo C. V. Jardim, Thiago V. Jardim, James Steele, James P. Fisher, Paulo Gentil
Molecular analysis of inherited cardiomyopathy using next generation semiconductor sequencing technologies
Chaoxia Lu, Wei Wu, Fang Liu, Kunqi Yang, Jiacheng Li, Yaping Liu, Rongrong Wang, Nuo Si, Peng Gao, Yongtai Liu, Shuyang Zhang, Xue Zhang
Unleashing endogenous TNF-alpha as a cancer immunotherapeutic
Steven F. Josephs, Thomas E. Ichim, Stephen M. Prince, Santosh Kesari, Francesco M. Marincola, Anton Rolando Escobedo, Amir Jafri
Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway
Mohamed A. Ghonim, Jeffrey Wang, Salome V. Ibba, Hanh H. Luu, Kusma Pyakurel, Ilyes Benslimane, Shaker Mousa, A. Hamid Boulares
Fecal microbiota and bile acid interactions with systemic and adipose tissue metabolism in diet-induced weight loss of obese postmenopausal women
José O. Alemán, Nicholas A. Bokulich, Jonathan R. Swann, Jeanne M. Walker, Joel Correa De Rosa, Thomas Battaglia, Adele Costabile, Alexandros Pechlivanis, Yupu Liang, Jan L. Breslow, Martin J. Blaser, Peter R. Holt
Effect of metformin on the survival of patients with ALL who express high levels of the ABCB1 drug resistance gene
Christian Ramos-Peñafiel, Irma Olarte-Carrillo, Rafael Cerón-Maldonado, Etta Rozen-Fuller, Juan Julio Kassack-Ipiña, Guillermo Meléndez-Mier, Juan Collazo-Jaloma, Adolfo Martínez-Tovar
Symptomatic anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow concentrate and platelet products: a non-controlled registry study
Christopher Centeno, Jason Markle, Ehren Dodson, Ian Stemper, Christopher Williams, Matthew Hyzy, Thomas Ichim, Michael Freeman
Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer
Matteo Pallocca, Frauke Goeman, Francesca De Nicola, Elisa Melucci, Francesca Sperati, Irene Terrenato, Laura Pizzuti, Beatrice Casini, Enzo Gallo, Carla Azzurra Amoreo, Patrizia Vici, Luigi Di Lauro, Simonetta Buglioni, Maria Grazia Diodoro, Edoardo Pescarmona, Marco Mazzotta, Maddalena Barba, Maurizio Fanciulli, Ruggero De Maria, Gennaro Ciliberto, Marcello Maugeri-Saccà
Unveiling metabolic remodeling in mucopolysaccharidosis type III through integrative metabolomics and pathway analysis
Abdellah Tebani, Lenaig Abily-Donval, Isabelle Schmitz-Afonso, Bénédicte Héron, Monique Piraud, Jérôme Ausseil, Farid Zerimech, Bruno Gonzalez, Stéphane Marret, Carlos Afonso, Soumeya Bekri
CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5
Dirk Lassner, Christine S. Siegismund, Uwe Kühl, Maria Rohde, Andrea Stroux, Felicitas Escher, Heinz-Peter Schultheiss
Multi-focused psychosocial residential rehabilitation interventions improve quality of life among cancer survivors: a community-based controlled trial
Xuefen Chen, Xiaohuan Gong, Changhong Shi, Li Sun, Zheng Tang, Zhengping Yuan, Jiwei Wang, Jinming Yu
Circulating tumor cells criteria (CyCAR) versus standard RECIST criteria for treatment response assessment in metastatic colorectal cancer patients
Mayte Delgado-Ureña, Francisco G. Ortega, Diego de Miguel-Pérez, Alba Rodriguez-Martínez, Jose L. García-Puche, Hugh Ilyine, Jose A. Lorente, Jose Exposito-Hernandez, M. Carmen Garrido-Navas, Miguel Delgado-Ramirez, M. José Serrano
The triennial International Pigment Cell Conference (IPCC)
Neil F. Box, Lionel Larue, Prashiela Manga, Lluis Montoliu, Richard A. Spritz, Fabian V. Filipp
Differential responses of MET activations to MET kinase inhibitor and neutralizing antibody
Jianqun Kou, Phillip R. Musich, Ben Staal, Liang Kang, Yuan Qin, Zhi Q. Yao, Boheng Zhang, Weizhong Wu, Angela Tam, Alan Huang, Huai-Xiang Hao, George F. Vande Woude, Qian Xie
Sex-specific associations between telomere length and candidate miRNA expression in placenta
Maria Tsamou, Dries S. Martens, Bianca Cox, Narjes Madhloum, Karen Vrijens, Tim S. Nawrot
Increased circulating endothelial progenitor cells and improved short-term outcomes in acute non-cardioembolic stroke after hyperbaric oxygen therapy
Chen-Yu Chen, Re-Wen Wu, Nai-Wen Tsai, Mel S. Lee, Wei-Che Lin, Mei-Chi Hsu, Chih-Cheng Huang, Yun-Ru Lai, Chia-Te Kung, Hung-Chen Wang, Yu-Jih Su, Chih-Min Su, Sheng-Yuan Hsiao, Ben-Chung Cheng, Yi-Fang Chiang, Cheng-Hsien Lu
MAGIC: once upon a time in consent management—a FHIR® tale
Martin Bialke, Thomas Bahls, Lars Geidel, Henriette Rau, Arne Blumentritt, Sandra Pasewald, Robert Wolff, Jonas Steinmann, Tobias Bronsch, Björn Bergh, Galina Tremper, Martin Lablans, Frank Ückert, Stefan Lang, Tarik Idris, Wolfgang Hoffmann
The diagnostic value of [18F]-FDG-PET/CT in assessment of radiation renal injury in Tibet minipigs model
Yu-Guang Tian, Min Yue, Bayaer Nashun, Shao-Jie Wu, Wei-Wang Gu, Yu-Jue Wang
The role of diffusion tensor imaging as an objective tool for the assessment of motor function recovery after paraplegia in a naturally-occurring large animal model of spinal cord injury
Adriano Wang-Leandro, Marc K. Hobert, Sabine Kramer, Karl Rohn, Veronika M. Stein, Andrea Tipold
Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas
Nicolas Jonckheere, Isabelle Van Seuningen
A loss-of-function mutation p.T52S in RIPPLY3 is a potential predisposing genetic risk factor for Chinese Han conotruncal heart defect patients without the 22q11.2 deletion/duplication
Nanchao Hong, Erge Zhang, Qingjie Wang, Xiaoqing Zhang, Fen Li, Qihua Fu, Rang Xu, Yu Yu, Sun Chen, Yuejuan Xu, Kun Sun
Predictive values of the selected inflammatory index in elderly patients with papillary thyroid cancer
Weiheng Wen, Peili Wu, Jitong Li, He Wang, Jia Sun, Hong Chen
Roles of airway smooth muscle dysfunction in chronic obstructive pulmonary disease
Furong Yan, Hongzhi Gao, Hong Zhao, Madhav Bhatia, Yiming Zeng
China Intracranial Aneurysm Project (CIAP): protocol for a registry study on a multidimensional prediction model for rupture risk of unruptured intracranial aneurysms
Junfan Chen, Jian Liu, Yisen Zhang, Zhongbin Tian, Kun Wang, Ying Zhang, Shiqing Mu, Ming Lv, Peng Jiang, ChuanZhi Duan, Hongqi Zhang, Yan Qu, Min He, Xinjian Yang
Systematic analysis of lncRNA–miRNA–mRNA competing endogenous RNA network identifies four-lncRNA signature as a prognostic biomarker for breast cancer
Chun-Ni Fan, Lei Ma, Ning Liu
Identification of serum β-catenin as a biomarker in patients with HBV-related liver diseases
Liang Duan, Qianfan Yang, Jun Yang, Qin Hu, Bo Wang, Pu Li, Weixian Chen
Identification of invasion-metastasis-associated microRNAs in hepatocellular carcinoma based on bioinformatic analysis and experimental validation
Weiyang Lou, Jing Chen, Bisha Ding, Danni Chen, Huilin Zheng, Donghai Jiang, Liang Xu, Chang Bao, Guoqiang Cao, Weimin Fan
MiR-425 expression profiling in acute myeloid leukemia might guide the treatment choice between allogeneic transplantation and chemotherapy
Chen Yang, Tingting Shao, Huihui Zhang, Ninghan Zhang, Xiaoying Shi, Xuejiao Liu, Yao Yao, Linyan Xu, Shengyun Zhu, Jiang Cao, Hai Cheng, Zhiling Yan, Zhenyu Li, Mingshan Niu, Kailin Xu
Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Santa Rasa, Zaiga Nora-Krukle, Nina Henning, Eva Eliassen, Evelina Shikova, Thomas Harrer, Carmen Scheibenbogen, Modra Murovska, Bhupesh K. Prusty
Cell adhesion-related gene somatic mutations are enriched in aggressive papillary thyroid microcarcinomas
Jianlu Song, Shouxin Wu, Xiaotian Xia, Yu Wang, Youben Fan, Zhili Yang
Subtype-specific associations between breast cancer risk polymorphisms and the survival of early-stage breast cancer
Fangmeng Fu, Wenhui Guo, Yuxiang Lin, Bangwei Zeng, Wei Qiu, Meng Huang, Chuan Wang
Surgical peritoneal stress creates a pro-metastatic niche promoting resistance to apoptosis via IL-8
Jennifer Pasquier, Fabien Vidal, Jessica Hoarau-Véchot, Claire Bonneau, Emile Daraï, Cyril Touboul, Arash Rafii
Screening and identification of potential novel biomarker for diagnosis of complicated Plasmodium vivax malaria
Hargobinder Kaur, Rakesh Sehgal, Archit Kumar, Alka Sehgal, Devendra Bansal, Ali A. Sultan
The systemic immune-inflammation index is an independent predictor of survival for metastatic colorectal cancer and its association with the lymphocytic response to the tumor
Qian-Kun Xie, Ping Chen, Wan-Ming Hu, Peng Sun, Wen-Zhuo He, Chang Jiang, Peng-Fei Kong, Shou-Sheng Liu, Hai-Tian Chen, Yuan-Zhong Yang, Dan Wang, Lin Yang, Liang-Ping Xia
Molecular network-based identification of competing endogenous RNAs and mRNA signatures that predict survival in prostate cancer
Ning Xu, Yu-Peng Wu, Hu-Bin Yin, Xue-Yi Xue, Xin Gou
Correction to: Cytokines induced killer cells produced in good manufacturing practices conditions: identification of the most advantageous and safest expansion method in terms of viability, cellular growth and identity
Sara Castiglia, Aloe Adamini, Deborah Rustichelli, Laura Castello, Katia Mareschi, Giuseppe Pinnetta, Marco Leone, Alessandra Mandese, Ivana Ferrero, Giulia Mesiano, Franca Fagioli
Tailoring cells for clinical needs: Meeting report from the Advanced Therapy in Healthcare symposium (October 28–29 2017, Doha, Qatar)
Sara Deola, Bella S. Guerrouahen, Heba Sidahmed, Anjud Al-Mohannadi, Muhammad Elnaggar, Ramaz Elsadig, Essam M. Abdelalim, Goran Petrovski, Massimo Gadina, Adrian Thrasher, Winfried S. Wels, Stephen P. Hunger, Ena Wang, Francesco M. Marincola, Maria Ester Bernardo, Patrizia Comoli, Kevin Curran, Graham Davies, Gianpietro Dotti, Mamoun Elawad, Soldano Ferrone, Antonia Follenzi, Ramsay Fuleihan, Amar Gajjar, Amel Hassan, Ziyad Hijazi, Katarina Le Blanc, Michele Maio, Eoin McGrath, Peter Parham, Lorenzo Piemonti, Matthew Porteus, Waseem Qasim, Raya Saab, David Stroncek, Fewzi Teskrat, Abdalla E. Zarroug, Cristina Maccalli, Chiara Cugno
Plasma interleukin-37 is increased and inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells in systemic juvenile idiopathic arthritis patients
Miao Feng, Min Kang, Feng He, Zonghui Xiao, Zhewei Liu, Hailan Yao, Jianxin Wu
Establishment of urinary exosome-like vesicles isolation protocol for FHHNC patients and evaluation of different exosomal RNA extraction methods
M. Vall-Palomar, J. Arévalo, G. Ariceta, A. Meseguer
A lipidated bi-epitope vaccine comprising of MHC-I and MHC-II binder peptides elicits protective CD4 T cell and CD8 T cell immunity against Mycobacterium tuberculosis
Pradeep K. Rai, Sathi Babu Chodisetti, Sudeep K. Maurya, Sajid Nadeem, Weiguang Zeng, Ashok K. Janmeja, David C. Jackson, Javed N. Agrewala
The development of a Biobank of cancer tissue samples from World Trade Center responders
Wil Lieberman-Cribbin, Stephanie Tuminello, Christina Gillezeau, Maaike van Gerwen, Rachel Brody, Michael Donovan, Emanuela Taioli
Boswellia frereana suppresses HGF-mediated breast cancer cell invasion and migration through inhibition of c-Met signalling
Christian Parr, Ahmed Y. Ali
p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification
Kun Tian, Emyr Bakker, Michelle Hussain, Alice Guazzelli, Hasen Alhebshi, Parisa Meysami, Constantinos Demonacos, Jean-Marc Schwartz, Luciano Mutti, Marija Krstic-Demonacos
Correction to: Harnessing Qatar Biobank to understand type 2 diabetes and obesity in adult Qataris from the First Qatar Biobank Project
Ehsan Ullah, Raghvendra Mall, Reda Rawi, Naima Moustaid-Moussa, Adeel A. Butt, Halima Bensmail
Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis
Yaoqin Yuan, Dongzi Lin, Long Feng, Mingyuan Huang, Huimin Yan, Yumei Li, Yinwen Chen, Bihua Lin, Yan Ma, Ziyu Ye, Yuezhi Mei, Xiaolin Yu, Keyuan Zhou, Qunzhou Zhang, Tao Chen, Jincheng Zeng
Joint associations of serum uric acid and ALT with NAFLD in elderly men and women: a Chinese cross-sectional study
Huanhuan Yang, Deming Li, Xiaochao Song, Fang Liu, Xinjing Wang, Qinghua Ma, Xi Zhang, Xinli Li
Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients
Annacarmen Petrizzo, Maria Tagliamonte, Angela Mauriello, Valerio Costa, Marianna Aprile, Roberta Esposito, Andrea Caporale, Antonio Luciano, Claudio Arra, Maria Lina Tornesello, Franco M. Buonaguro, Luigi Buonaguro
Analysis of circulating tumour cell and the epithelial mesenchymal transition (EMT) status during eribulin-based treatment in 22 patients with metastatic breast cancer: a pilot study
Yoshiya Horimoto, Emi Tokuda, Fumi Murakami, Toshitaka Uomori, Takanori Himuro, Katsuya Nakai, Gotaro Orihata, Kotaro Iijima, Shinsaku Togo, Hideo Shimizu, Mitsue Saito
A modified method for isolation of human cardiomyocytes to model cardiac diseases
Guang-ran Guo, Liang Chen, Man Rao, Kai Chen, Jiang-ping Song, Sheng-shou Hu
Heterogeneity of insulin resistance and beta cell dysfunction in gestational diabetes mellitus: a prospective cohort study of perinatal outcomes
Yingfeng Liu, Wolin Hou, Xiyan Meng, Weijing Zhao, Jiemin Pan, Junling Tang, Yajuan Huang, Minfang Tao, Fang Liu
Podocalyxin-like protein as a predictive biomarker for benefit of neoadjuvant chemotherapy in resectable gastric and esophageal adenocarcinoma
David Borg, Anna H. Larsson, Charlotta Hedner, Björn Nodin, Anders Johnsson, Karin Jirström
Stability enhancement of clinical grade multipotent mesenchymal stromal cell-based products
Clémentine Mirabel, Eduard Puente-Massaguer, Anna del Mazo-Barbara, Blanca Reyes, Philip Morton, Francesc Gòdia, Joaquim Vives
Genomic approaches in the search for molecular biomarkers in chronic kidney disease
M. Cañadas-Garre, K. Anderson, J. McGoldrick, A. P. Maxwell, A. J. McKnight
iTRAQ-based quantitative analysis of age-specific variations in salivary proteome of caries-susceptible individuals
Kun Wang, Xiuqing Wang, Sainan Zheng, Yumei Niu, Wenyue Zheng, Xi Qin, Zhongcheng Li, Junyuan Luo, Wentao Jiang, Xuedong Zhou, Wei Li, Linglin Zhang
CD25 and TGF-β blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer
Ning Pu, Guochao Zhao, Hanlin Yin, Jian-ang Li, Abulimiti Nuerxiati, Dansong Wang, Xuefeng Xu, Tiantao Kuang, Dayong Jin, Wenhui Lou, Wenchuan Wu
An increase in myocardial 18-fluorodeoxyglucose uptake is associated with left ventricular ejection fraction decline in Hodgkin lymphoma patients treated with anthracycline
Matteo Sarocchi, Matteo Bauckneht, Eleonora Arboscello, Selene Capitanio, Cecilia Marini, Silvia Morbelli, Maurizio Miglino, Angela Giovanna Congiu, Giorgio Ghigliotti, Manrico Balbi, Claudio Brunelli, Gianmario Sambuceti, Pietro Ameri, Paolo Spallarossa
The immune response to sub-clinical mastitis is impaired in HIV-infected women
Roxane Schaub, Stéphanie Badiou, Johannes Viljoen, Pierre Dujols, Karine Bolloré, Philippe Van de Perre, Marie-Louise Newell, Ruth Bland, Nicolas Nagot, Edouard Tuaillon
Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance
Lin Wang, Zhong Sheng Sun, Bingwu Xiang, Chi-ju Wei, Yan Wang, Kevin Sun, Guanjie Chen, Michael S. Lan, Gilberto N. Carmona, Abner L. Notkins, Tao Cai
Peptide vaccine against chikungunya virus: immuno-informatics combined with molecular docking approach
Muhammad Tahir ul Qamar, Amna Bari, Muhammad Muzammal Adeel, Arooma Maryam, Usman Ali Ashfaq, Xiaoyong Du, Iqra Muneer, Hafiz Ishfaq Ahmad, Jia Wang
Galectin-3 predicts response and outcomes after cardiac resynchronization therapy
Clémentine Andre, Eric Piver, Romain Perault, Arnaud Bisson, Julien Pucheux, Emmanuelle Vermes, Bertrand Pierre, Laurent Fauchier, Dominique Babuty, Nicolas Clementy
Fragment size and level of cell-free DNA provide prognostic information in patients with advanced pancreatic cancer
Morten Lapin, Satu Oltedal, Kjersti Tjensvoll, Tove Buhl, Rune Smaaland, Herish Garresori, Milind Javle, Nils Idar Glenjen, Bente Kristin Abelseth, Bjørnar Gilje, Oddmund Nordgård
Analysis of longitudinal semicontinuous data using marginalized two-part model
Miran A. Jaffa, Mulugeta Gebregziabher, Sara M. Garrett, Deirdre K. Luttrell, Kenneth E. Lipson, Louis M. Luttrell, Ayad A. Jaffa
Periostin involved in the activated hepatic stellate cells-induced progression of residual hepatocellular carcinoma after sublethal heat treatment: its role and potential for therapeutic inhibition
Rui Zhang, Xia-Hui Lin, Min Ma, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Rong-Xin Chen
Status of programmed death-ligand 1 expression in sarcomas
Hyung Kyu Park, Mingi Kim, Minjung Sung, Seung Eun Lee, Yu Jin Kim, Yoon-La Choi
Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail
Pandora Pound, Merel Ritskes-Hoitinga
Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis
Ae Ri Kim, Ji-Hye Kim, Aeryun Kim, Yongsung Sohn, Jeong-Heon Cha, Eun-Jung Bak, Yun-Jung Yoo
Significance of intrinsic breast cancer subtypes on the long-term prognosis after neoadjuvant chemotherapy
Wataru Goto, Shinichiro Kashiwagi, Koji Takada, Yuka Asano, Katsuyuki Takahashi, Hisakazu Fujita, Tsutomu Takashima, Shuhei Tomita, Kosei Hirakawa, Masaichi Ohira
Influence of FTO rs9939609 and Mediterranean diet on body composition and weight loss: a randomized clinical trial
Laura Di Renzo, Giorgia Cioccoloni, Simone Falco, Ludovico Abenavoli, Alessandra Moia, Paola Sinibaldi Salimei, Antonino De Lorenzo
High density lipoprotein cholesterol and proteome in SR-B1 KO mice: lost in precipitation
Susana Contreras-Duarte, Nicolás Santander, Ruth Birner-Gruenberger, Christian Wadsack, Attilio Rigotti, Dolores Busso
GAP43, a novel metastasis promoter in non-small cell lung cancer
Fanrong Zhang, Lisha Ying, Jiaoyue Jin, Jianguo Feng, Kaiyan Chen, Minran Huang, Yingxue Wu, Herbert Yu, Dan Su
Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors
Qi Luo, Guangyu Wei, Xiaoqing Wu, Kai Tang, Mengdi Xu, Yulu Wu, Yun Liu, Xiaoqian Li, Zengtian Sun, Wen Ju, Kunming Qi, Chong Chen, Zhiling Yan, Hai Cheng, Feng Zhu, Zhenyu Li, Lingyu Zeng, Kailin Xu, Jianlin Qiao
Association of serum angiopoietin-2 with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients: a prospective cohort study
Xiaoxiao Yang, He Zhang, Yuanyuan Shi, Zanzhe Yu, Hao Yan, Zhaohui Ni, Jiaqi Qian, Wei Fang
Sirtuin 3 deficiency aggravates contrast-induced acute kidney injury
Qinghai Zhang, Xun Liu, Na li, Jihong Zhang, Jianmin Yang, Peili Bu
Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia
Kyosuke Yamanishi, Seishi Maeda, Sachi Kuwahara-Otani, Takuya Hashimoto, Kaoru Ikubo, Keiichiro Mukai, Keiji Nakasho, Naomi Gamachi, Yosif El-Darawish, Wen Li, Daisuke Okuzaki, Yuko Watanabe, Hiromichi Yamanishi, Haruki Okamura, Hisato Matsunaga
Associations of immunological factors with metabolic syndrome and its characteristic elements in Chinese centenarians
Shihui Fu, Yao Yao, Faqin Lv, Fu Zhang, Yali Zhao, Fuxin Luan
Serum uromodulin and progression of kidney disease in patients with chronic kidney disease
Li Lv, Jinwei Wang, Bixia Gao, Liang Wu, Fang Wang, Zhao Cui, Kevin He, Luxia Zhang, Min Chen, Ming-Hui Zhao
NLRC5: potential novel non-invasive biomarker for predicting and reflecting the progression of IgA nephritis
Yusa Chen, Huihui Li, Chenggen Xiao, Xiangli Zeng, Xiangcheng Xiao, Qiaoling Zhou, Ping Xiao
Possibility of avoiding axillary lymph node dissection by immune microenvironment monitoring in preoperative chemotherapy for breast cancer
Koji Takada, Shinichiro Kashiwagi, Wataru Goto, Yuka Asano, Katsuyuki Takahashi, Hisakazu Fujita, Tsutomu Takashima, Shuhei Tomita, Kosei Hirakawa, Masaichi Ohira
Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway
Xiaobo Gao, Shun Guo, Song Zhang, An Liu, Lei Shi, Yan Zhang
Clinicopathologic implication of PD-L1 and phosphorylated STAT3 expression in diffuse large B cell lymphoma
Hyun Jung Kwon, Jeong Mi Yang, Jeong-Ok Lee, Jong Seok Lee, Jin Ho Paik
Optimizing bone wound healing using BMP2 with absorbable collagen sponge and Talymed nanofiber scaffold
Emily L. Durham, R. Nicole Howie, SarahRose Hall, Nicholas Larson, Brayden Oakes, Reed Houck, Zachary Grey, Martin Steed, Amanda C. LaRue, Robin Muise-Helmericks, James Cray
Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis
Kenny L. De Meirleir, Tatjana Mijatovic, Krishnamurthy Subramanian, Karen A. Schlauch, Vincent C. Lombardi
N-glycosylation patterns of plasma proteins and immunoglobulin G in chronic obstructive pulmonary disease
Tamara Pavić, Dario Dilber, Domagoj Kifer, Najda Selak, Toma Keser, Đivo Ljubičić, Andrea Vukić Dugac, Gordan Lauc, Lada Rumora, Olga Gornik
Effects of physiological aging factor on bone tissue engineering repair based on fetal BMSCs
Dingyu Wu, Zhenxing Wang, Zhiwei Zheng, Yingnan Geng, Zhanzhao Zhang, Qiannan Li, Quan Zhou, Yilin Cao, Zhi-Yong Zhang
Feasibility study of dual parametric 2D histogram analysis of breast lesions with dynamic contrast-enhanced and diffusion-weighted MRI
Yanqiong Chen, Bin Wu, Hui Liu, Dan Wang, Yajia Gu
Therapeutic value of surgical paraaortic staging in locally advanced cervical cancer: a multicenter cohort analysis from the FRANCOGYN study group
Yohann Dabi, Vanille Simon, Xavier Carcopino, Sofiane Bendifallah, Lobna Ouldamer, Vincent Lavoue, Geoffroy Canlorbe, Emilie Raimond, Charles Coutant, Olivier Graesslin, Pierre Collinet, Alexandre Bricou, Emile Daraï, Cyrille Huchon, Marcos Ballester, Bassam Haddad, Cyril Touboul
Evaluation of the prognostic value of paraoxonase 1 in the recurrence and metastasis of hepatocellular carcinoma and establishment of a liver-specific predictive model of survival
Zheng Yu, Qifeng Ou, Fan Chen, Jiong Bi, Wen Li, Jieyi Ma, Rongchang Wang, Xiaohui Huang
Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer
Xingxiang Pu, Ran Zhang, Li Wang, Yungchang Chen, Yi Xu, Apar Pataer, Ismail M. Meraz, Xiaoshan Zhang, Shuhong Wu, Lin Wu, Dan Su, Weimin Mao, John V. Heymach, Jack A. Roth, Stephen G. Swisher, Bingliang Fang
Epicutaneous immunotherapy in rhino-conjunctivitis and food allergies: a review of the literature
Susanna Esposito, Chiara Isidori, Alessandra Pacitto, Cristina Salvatori, Laura Sensi, Franco Frati, Giuseppe Di Cara, Francesco Marcucci
Mutational and phenotypic spectrum of OTOF-related auditory neuropathy in Koreans: eliciting reciprocal interaction between bench and clinics
Bong Jik Kim, Jeong Hun Jang, Jin Hee Han, Hye-Rim Park, Doo Yi Oh, Seungmin Lee, Min Young Kim, Ah Reum Kim, Chung Lee, Nayoung K. D. Kim, Woong-Yang Park, Yun-Hoon Choung, Byung Yoon Choi
Early goal-directed and lactate-guided therapy in adult patients with severe sepsis and septic shock: a meta-analysis of randomized controlled trials
Xian-Fei Ding, Zi-Yue Yang, Zhen-Tao Xu, Li-Feng Li, Bo Yuan, Li-Na Guo, Le-Xin Wang, Xi Zhu, Tong-Wen Sun
Crosstalk in competing endogenous RNA networks reveals new circular RNAs involved in the pathogenesis of early HIV infection
Yue Zhang, Hui Zhang, Minghui An, Bin Zhao, Haibo Ding, Zining Zhang, Youwen He, Hong Shang, Xiaoxu Han
Scrub typhus and depression: a nationwide cohort analysis
Ying-Chuan Wang, Chun-Hsiang Chiu, Cheng-Li Lin, Feng-You Lee, Kuang-Hsi Chang
Machine-learned models using hematological inflammation markers in the prediction of short-term acute coronary syndrome outcomes
Konrad Pieszko, Jarosław Hiczkiewicz, Paweł Budzianowski, Janusz Rzeźniczak, Jan Budzianowski, Jerzy Błaszczyński, Roman Słowiński, Paweł Burchardt
Autoimmune disorders but not heparin are associated with cell-free fetal DNA test failure
Yohann Dabi, Sarah Guterman, Jacques C. Jani, Alexandra Letourneau, Adèle Demain, Pascale Kleinfinger, Laurence Lohmann, Jean-Marc Costa, Alexandra Benachi
Reviewing the role of healthy volunteer studies in drug development
Joyson J. Karakunnel, Nam Bui, Latha Palaniappan, Keith T. Schmidt, Kenneth W. Mahaffey, Briggs Morrison, William D. Figg, Shivaani Kummar
The treatment value of IL-1β monoclonal antibody under the targeting location of alpha-methyl-l-tryptophan and superparamagnetic iron oxide nanoparticles in an acute temporal lobe epilepsy model
Yanli Wang, Yanling Wang, Ran Sun, Xingrao Wu, Xu Chu, Shuhu Zhou, Xibin Hu, Lingyun Gao, Qingxia Kong
Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis
Clara Benna, Senthilkumar Rajendran, Giovanna Spiro, Saveria Tropea, Paolo Del Fiore, Carlo Riccardo Rossi, Simone Mocellin
Immunological effects of the intraparenchymal administration of allogeneic and autologous adipose-derived mesenchymal stem cells after the acute phase of middle cerebral artery occlusion in rats
Zhang Yu, Tang Wenyan, Su Xuewen, Dong Baixiang, Wang Qian, Wang Zhaoyan, Yang Yinxiang, Qu Suqing, Luan Zuo
Diffusion-weighted imaging and diffusion kurtosis imaging for early evaluation of the response to docetaxel in rat epithelial ovarian cancer
Su-juan Yuan, Tian-kui Qiao, Jin-Wei Qiang
microRNA expression pattern as an ancillary prognostic signature for radiotherapy
An-Lun Li, Tao-Sang Chung, Yao-Ning Chan, Chien-Lung Chen, Shih-Chieh Lin, Yun-Ru Chiang, Chen-Huan Lin, Chi-Ching Chen, Nianhan Ma
Increased risk of chronic fatigue syndrome following burn injuries
Shin-Yi Tsai, Cheng-Li Lin, Shou-Chuan Shih, Cheng-Wei Hsu, Kam-Hang Leong, Chien-Feng Kuo, Chon-Fu Lio, Yu-Tien Chen, Yan-Jiun Hung, Leiyu Shi
Mitochondrial haplogroup H is related to CD4+ T cell recovery in HIV infected patients starting combination antiretroviral therapy
Luz M. Medrano, Mónica Gutiérrez-Rivas, Julià Blanco, Marcial García, María A. Jiménez-Sousa, Yolanda M. Pacheco, Marta Montero, José Antonio Iribarren, Enrique Bernal, Onofre Juan Martínez, José M. Benito, Norma Rallón, Salvador Resino
l-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice
Guangyan Wu, Mengwei Niu, Wenli Tang, Jingjuan Hu, Guoquan Wei, Zhanke He, Yangping Chen, Yong Jiang, Peng Chen
Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease
Ye-Xuan Cao, Na-Qiong Wu, Di Sun, Hui-Hui Liu, Jing-Lu Jin, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Qiu-Ting Dong, Geng Liu, Qian Dong, Jian-Jun Li
Real-world use of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers/β-blocks in Chinese patients before acute myocardial infarction occurs: patient characteristics and hospital follow-up
Xuhe Gong, Xiaosong Ding, Hui Chen, Hongwei Li
Dexmedetomidine expands monocytic myeloid-derived suppressor cells and promotes tumour metastasis after lung cancer surgery
Xiaosan Su, Yaodong Fan, Liu Yang, Jie Huang, Fei Qiao, Yu Fang, Jun Wang
A heterogeneous label propagation approach to explore the potential associations between miRNA and disease
Xing Chen, De-Hong Zhang, Zhu-Hong You
Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma
Joseph A. Impellizeri, Alessandra Gavazza, Eliana Greissworth, Anna Crispo, Maurizio Montella, Gennaro Ciliberto, George Lubas, Luigi Aurisicchio
Posterior HOX genes and HOTAIR expression in the proximal and distal colon cancer pathogenesis
Fabiana Tatangelo, Annabella Di Mauro, Giosuè Scognamiglio, Gabriella Aquino, Antonio Lettiero, Paolo Delrio, Antonio Avallone, Monica Cantile, Gerardo Botti
Measurement of hepatitis B virus DNA in fresh versus processed dentin from chronically infected patients
Inwoong Um, Sungweon Choi, Youngkyun Kim, Kangmi Pang, Jongho Lee, Minsun Lee, Bongju Kim
Integrin ανβ5 in vitro inhibition limits pro-fibrotic response in cardiac fibroblasts of spontaneously hypertensive rats
Gianluca Lorenzo Perrucci, Veronica Antonietta Barbagallo, Maria Corlianò, Delfina Tosi, Rosaria Santoro, Patrizia Nigro, Paolo Poggio, Gaetano Bulfamante, Federico Lombardi, Giulio Pompilio
Gut microbiota dysbiosis in male patients with chronic traumatic complete spinal cord injury
Chao Zhang, Wenhao Zhang, Jie Zhang, Yingli Jing, Mingliang Yang, Liangjie Du, Feng Gao, Huiming Gong, Liang Chen, Jun Li, Hongwei Liu, Chuan Qin, Yanmei Jia, Jiali Qiao, Bo Wei, Yan Yu, Hongjun Zhou, Zhizhong Liu, Degang Yang, Jianjun Li
Diverse roles of macrophage polarization in aortic aneurysm: destruction and repair
Zhao Cheng, Yang-zhao Zhou, Yin Wu, Qi-ying Wu, Xiao-bo Liao, Xian-ming Fu, Xin-min Zhou
A specific protocol of autologous bone marrow concentrate and platelet products versus exercise therapy for symptomatic knee osteoarthritis: a randomized controlled trial with 2 year follow-up
Christopher Centeno, Mitchell Sheinkop, Ehren Dodson, Ian Stemper, Christopher Williams, Matthew Hyzy, Thomas Ichim, Michael Freeman
Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer
Monika Pizon, Daniel Lux, Ulrich Pachmann, Katharina Pachmann, Dorothea Schott
A novel semi-supervised model for miRNA-disease association prediction based on -norm graph
Cheng Liang, Shengpeng Yu, Ka-Chun Wong, Jiawei Luo
Implementing a comprehensive translational oncology platform: from molecular testing to actionability
Zahi I. Mitri, Swapnil Parmar, Brett Johnson, Annette Kolodzie, Jamie M. Keck, Max Morris, Alexander R. Guimaraes, Brooke R. Beckett, Uma Borate, Charles D. Lopez, Kathleen A. Kemmer, Joshi J. Alumkal, Tomasz M. Beer, Christopher L. Corless, Gordon B. Mills, Joe W. Gray, Raymond C. Bergan
Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease
Ritian Lin, Hongwei Chen, Weigang Shu, Mingming Sun, Leilei Fang, Yanhong Shi, Zhi Pang, Wei Wu, Zhanju Liu
The ruxolitinib effect: understanding how molecular pathogenesis and epigenetic dysregulation impact therapeutic efficacy in myeloproliferative neoplasms
Graeme Greenfield, Suzanne McPherson, Ken Mills, Mary Frances McMullin
Circular RNA regulatory network reveals cell–cell crosstalk in acute myeloid leukemia extramedullary infiltration
Chengfang Lv, Lili Sun, Zhibo Guo, Huibo Li, Desheng Kong, Bingqi Xu, Leilei Lin, Tianjiao Liu, Dan Guo, Jin Zhou, Yinghua Li
The roles of HLA-DQB1 gene polymorphisms in hepatitis B virus infection
Guojin Ou, Haixia Xu, Hao Yu, Xiao Liu, Liu Yang, Xin Ji, Jue Wang, Zhong Liu
Prediction and prognostic significance of BCAR3 expression in patients with multiple myeloma
Weilong Zhang, Yuansheng Lin, Xiaoni Liu, Xue He, Ye Zhang, Wei Fu, Zuozhen Yang, Ping Yang, Jing Wang, Kai Hu, Xiuru Zhang, Weiyou Liu, Xiaoliang Yuan, Hongmei Jing
Pro-atherosclerotic disturbed flow disrupts caveolin-1 expression, localization, and function via glycocalyx degradation
Ian C. Harding, Ronodeep Mitra, Solomon A. Mensah, Ira M. Herman, Eno E. Ebong
Preoperative systemic immune-inflammation index predicts prognosis of patients with oral squamous cell carcinoma after curative resection
Pengfei Diao, Yaping Wu, Jin Li, Wei Zhang, Rong Huang, Chen Zhou, Yanling Wang, Jie Cheng
Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer
Yoshinaga Okugawa, Yuji Toiyama, Kunitoshi Shigeyasu, Akira Yamamoto, Tsunehiko Shigemori, Chengzeng Yin, Takashi Ichikawa, Hiromi Yasuda, Hiroyuki Fujikawa, Shigeyuki Yoshiyama, Junichiro Hiro, Masaki Ohi, Toshimitsu Araki, Masato Kusunoki, Ajay Goel
Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery
Lisanne L. de Boer, Torre M. Bydlon, Frederieke van Duijnhoven, Marie-Jeanne T. F. D. Vranken Peeters, Claudette E. Loo, Gonneke A. O. Winter-Warnars, Joyce Sanders, Henricus J. C. M. Sterenborg, Benno H. W. Hendriks, Theo J. M. Ruers
Identification of a multidimensional transcriptome signature for survival prediction of postoperative glioblastoma multiforme patients
Wei-Zhen Gao, Lie-Mei Guo, Tian-Qi Xu, Yu-Hua Yin, Feng Jia
Identification of a novel role of IL-13Rα2 in human Glioblastoma multiforme: interleukin-13 mediates signal transduction through AP-1 pathway
Rukmini Bhardwaj, Akiko Suzuki, Pamela Leland, Bharat H. Joshi, Raj K. Puri
NovelmiRNA-25 inhibits AMPD2 in peripheral blood mononuclear cells of patients with systemic lupus erythematosus and represents a promising novel biomarker
Gangqiang Guo, Huijing Wang, Xinyu Shi, Lele Ye, Kai Wu, Kangmin Lin, Sisi Ye, Baoqing Li, Huidi Zhang, Qiaoai Lin, Shuang Ye, Xiangyang Xue, Chaosheng Chen
Intermittent versus continuous energy restriction on weight loss and cardiometabolic outcomes: a systematic review and meta-analysis of randomized controlled trials
Iolanda Cioffi, Andrea Evangelista, Valentina Ponzo, Giovannino Ciccone, Laura Soldati, Lidia Santarpia, Franco Contaldo, Fabrizio Pasanisi, Ezio Ghigo, Simona Bo
Integrated analysis of dysregulated long non-coding RNAs/microRNAs/mRNAs in metastasis of lung adenocarcinoma
Lifeng Li, Mengle Peng, Wenhua Xue, Zhirui Fan, Tian Wang, Jingyao Lian, Yunkai Zhai, Wenping Lian, Dongchun Qin, Jie Zhao
Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms
Vincent M. Tutino, Kerry E. Poppenberg, Lu Li, Hussain Shallwani, Kaiyu Jiang, James N. Jarvis, Yijun Sun, Kenneth V. Snyder, Elad I. Levy, Adnan H. Siddiqui, John Kolega, Hui Meng
FGFR1 expression defines clinically distinct subtypes in pancreatic cancer
Farhan Haq, You-Na Sung, Inkeun Park, Mahmood Akhtar Kayani, Faizah Yousuf, Seung-Mo Hong, Sung-Min Ahn