Issue 1/2017
Content (262 Articles)
Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease
Charbel Moussa, Michaeline Hebron, Xu Huang, Jaeil Ahn, Robert A. Rissman, Paul S. Aisen, R. Scott Turner
Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
E. Soemirien Kasanmoentalib, Mercedes Valls Seron, Bart Ferwerda, Michael W. Tanck, Aeilko H. Zwinderman, Frank Baas, Arie van der Ende, Matthijs C. Brouwer, Diederik van de Beek
Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide
Ester Bonfill-Teixidor, Amaia Otxoa-de-Amezaga, Miriam Font-Nieves, M. Glòria Sans-Fons, Anna M. Planas
Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator
Sven Micklisch, Yuchen Lin, Saskia Jacob, Marcus Karlstetter, Katharina Dannhausen, Prasad Dasari, Monika von der Heide, Hans-Martin Dahse, Lisa Schmölz, Felix Grassmann, Medhanie Alene, Sascha Fauser, Harald Neumann, Stefan Lorkowski, Diana Pauly, Bernhard H. Weber, Antonia M. Joussen, Thomas Langmann, Peter F. Zipfel, Christine Skerka
Resolvin RvD2 reduces hypothalamic inflammation and rescues mice from diet-induced obesity
Livia B. Pascoal, Bruna Bombassaro, Albina F. Ramalho, Andressa Coope, Rodrigo F. Moura, Felipe Correa-da-Silva, Leticia Ignacio-Souza, Daniela Razolli, Diogo de Oliveira, Rodrigo Catharino, Licio A. Velloso
Enhanced neuroinflammation mediated by DNA methylation of the glucocorticoid receptor triggers cognitive dysfunction after sevoflurane anesthesia in adult rats subjected to maternal separation during the neonatal period
Yangzi Zhu, Yu Wang, Rui Yao, Ting Hao, Junli Cao, He Huang, Liwei Wang, Yuqing Wu
WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism
Mikiei Tanaka, Sean Moran, Jie Wen, Kwame Affram, Tinghua Chen, Aviva J. Symes, Yumin Zhang
Microglial activation in Parkinson’s disease using [18F]-FEPPA
Christine Ghadery, Yuko Koshimori, Sarah Coakeley, Madeleine Harris, Pablo Rusjan, Jinhee Kim, Sylvain Houle, Antonio P. Strafella
Absence of system xc − on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis
Ellen Merckx, Giulia Albertini, Magdalena Paterka, Cathy Jensen, Philipp Albrecht, Michael Dietrich, Joeri Van Liefferinge, Eduard Bentea, Lise Verbruggen, Thomas Demuyser, Lauren Deneyer, Jan Lewerenz, Geert van Loo, Jacques De Keyser, Hideyo Sato, Pamela Maher, Axel Methner, Ann Massie
Inflammation in epileptogenesis after traumatic brain injury
Kyria M. Webster, Mujun Sun, Peter Crack, Terence J. O’Brien, Sandy R. Shultz, Bridgette D. Semple
BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset
M. Puthenparampil, L. Federle, S. Miante, A. Zito, E. Toffanin, S. Ruggero, M. Ermani, S. Pravato, D. Poggiali, P. Perini, F. Rinaldi, P. Gallo
Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer’s disease
Chi-Wei Huang, Shih-Wei Hsu, Shih-Jen Tsai, Nai-Ching Chen, Mu-En Liu, Chen-Chang Lee, Shu-Hua Huang, Weng-Neng Chang, Ya-Ting Chang, Wan-Chen Tsai, Chiung-Chih Chang
Activation of human B cells negatively regulates TGF-β1 production
Nicolas Molnarfi, Kristbjörg Bjarnadóttir, Mahdia Benkhoucha, Catherine Juillard, Patrice H. Lalive
Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration
Lei Zhao, Jun Li, Yingmei Fu, Mengxue Zhang, Bowen Wang, Jonathan Ouellette, Pawan K. Shahi, Bikash R. Pattnaik, Jyoti J. Watters, Wai T. Wong, Lian-Wang Guo
Everolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures
Ming-Tao Yang, Yi-Chin Lin, Whae-Hong Ho, Chao-Lin Liu, Wang-Tso Lee
Interleukin-1 as a mediator of fatigue in disease: a narrative review
Megan E. Roerink, Marieke E. van der Schaaf, Charles A. Dinarello, Hans Knoop, Jos W. M. van der Meer
Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity
Wei-Xing Zhao, Jun-Han Zhang, Jiang-Bei Cao, Wei Wang, Dong-Xin Wang, Xiao-Ying Zhang, Jun Yu, Yong-Yi Zhang, You-Zhi Zhang, Wei-Dong Mi
Blocking of platelet glycoprotein receptor Ib reduces “thrombo-inflammation” in mice with acute ischemic stroke
Michael K. Schuhmann, Josua Guthmann, Guido Stoll, Bernhard Nieswandt, Peter Kraft, Christoph Kleinschnitz
Rab32 connects ER stress to mitochondrial defects in multiple sclerosis
Yohannes Haile, Xiaodan Deng, Carolina Ortiz-Sandoval, Nasser Tahbaz, Aleksandra Janowicz, Jian-Qiang Lu, Bradley J. Kerr, Nicholas J. Gutowski, Janet E. Holley, Paul Eggleton, Fabrizio Giuliani, Thomas Simmen
Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis
Jessica Freundt-Revilla, Arianna Maiolini, Regina Carlson, Martin Beyerbach, Kai Rentmeister, Thomas Flegel, Andrea Fischer, Andrea Tipold
Cerebral ischemic damage in diabetes: an inflammatory perspective
Vibha Shukla, Akhalesh Kumar Shakya, Miguel A. Perez-Pinzon, Kunjan R. Dave
Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7
Leon G. Coleman Jr, Jian Zou, Fulton T. Crews
HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis
Jadwiga Nitkiewicz, Alejandra Borjabad, Susan Morgello, Jacinta Murray, Wei Chao, Luni Emdad, Paul B. Fisher, Mary Jane Potash, David J. Volsky
Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons
María Calvo-Rodríguez, Carmen de la Fuente, Mónica García-Durillo, Carmen García-Rodríguez, Carlos Villalobos, Lucía Núñez
Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid
Soraya Wilke Saliba, Erica Leandro Marciano Vieira, Rebeca Priscila de Melo Santos, Eduardo Candelario-Jalil, Bernd L. Fiebich, Luciene Bruno Vieira, Antonio Lucio Teixeira, Antonio Carlos Pinheiro de Oliveira
Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin
Fernando Bartolome, Desiree Antequera, Eva Tavares, Consuelo Pascual, Rosario Maldonado, Antoni Camins, Eva Carro
Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study
Paula Gyllemark, Pia Forsberg, Jan Ernerudh, Anna J. Henningsson
Effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in glial and neuronal cells of the central nervous system
Geeta Ramesh, Alejandra N. Martinez, Dale S. Martin, Mario T. Philipp
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
Anthony J. Carlos, Liqi Tong, G. Aleph Prieto, Carl W. Cotman
Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis
Uta Baddack-Werncke, Melanie Busch-Dienstfertig, Sara González-Rodríguez, Santhosh Chandar Maddila, Jenny Grobe, Martin Lipp, Christoph Stein, Gerd Müller
Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
Catherine W. M. Ong, Przemyslaw J. Pabisiak, Sara Brilha, Poonam Singh, Federico Roncaroli, Paul T. Elkington, Jon S. Friedland
Combined effect of BCG vaccination and enriched environment promote neurogenesis and spatial cognition via a shift in meningeal macrophage M2 polarization
Fangfang Qi, Zejie Zuo, Junhua Yang, Saisai Hu, Yang Yang, Qunfang Yuan, Juntao Zou, Kaihua Guo, Zhibin Yao
Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia
Yafa Fetfet Malada-Edelstein, Nurit Hadad, Rachel Levy
The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia
Joanna Jaworska, Malgorzata Ziemka-Nalecz, Joanna Sypecka, Teresa Zalewska
Erratum to: SDF1 in the dorsal corticospinal tract promotes CXCR4+ cell migration after spinal cord injury
Vicki M. Tysseling, Divakar S. Mithal, Vibhu Sahni, Derin Birch, Hosung Jung, Richard J. Miller, John A. Kessler
Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype
Jie Wu, Liang Sun, Haiying Li, Haitao Shen, Weiwei Zhai, Zhengquan Yu, Gang Chen
Aprepitant limits in vivo neuroinflammatory responses in a rhesus model of Lyme neuroborreliosis
Alejandra N. Martinez, Amanda R. Burmeister, Geeta Ramesh, Lara Doyle-Meyers, Ian Marriott, Mario T. Philipp
Microglia P2Y6 receptor is related to Parkinson’s disease through neuroinflammatory process
Xiaodong Yang, Yue Lou, Guidong Liu, Xueping Wang, Yiwei Qian, Jianqing Ding, Shengdi Chen, Qin Xiao
Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
Sarah Hopp, Marc W. Nolte, Christian Stetter, Christoph Kleinschnitz, Anna-Leena Sirén, Christiane Albert-Weissenberger
Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study
Gabriele Farina, Roberta Magliozzi, Marco Pitteri, Richard Reynolds, Stefania Rossi, Alberto Gajofatto, Maria Donata Benedetti, Francesco Facchiano, Salvatore Monaco, Massimiliano Calabrese
Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculation
Katja Thomas, Tony Sehr, Undine Proschmann, Francisco Alejandro Rodriguez-Leal, Rocco Haase, Tjalf Ziemssen
Peripheral blood mononuclear cells from neovascular age-related macular degeneration patients produce higher levels of chemokines CCL2 (MCP-1) and CXCL8 (IL-8)
Judith Lechner, Mei Chen, Ruth E. Hogg, Levente Toth, Giuliana Silvestri, Usha Chakravarthy, Heping Xu
Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease
Tracoyia Roach, Donald J. Alcendor
Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model
Eridan Rocha-Ferreira, Dorottya Kelen, Stuart Faulkner, Kevin D. Broad, Manigandan Chandrasekaran, Áron Kerenyi, Takenori Kato, Alan Bainbridge, Xavier Golay, Mark Sullivan, Boris W. Kramer, Nicola J. Robertson
Molecular imaging of nestin in neuroinflammatory conditions reveals marked signal induction in activated microglia
Senthil Krishnasamy, Yuan-Cheng Weng, Sai Sampath Thammisetty, Daniel Phaneuf, Melanie Lalancette-Hebert, Jasna Kriz
Pleiotrophin regulates microglia-mediated neuroinflammation
Rosalía Fernández-Calle, Marta Vicente-Rodríguez, Esther Gramage, Jimena Pita, Carmen Pérez-García, Marcel Ferrer-Alcón, María Uribarri, María P. Ramos, Gonzalo Herradón
Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury
Alok Kumar, Bogdan A. Stoica, David J. Loane, Ming Yang, Gelareh Abulwerdi, Niaz Khan, Asit Kumar, Stephen R. Thom, Alan I. Faden
Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain
Maria I. Fonseca, Shu-Hui Chu, Michael X. Hernandez, Melody J. Fang, Lila Modarresi, Pooja Selvan, Grant R. MacGregor, Andrea J. Tenner
Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro
Nikki Bortell, Liana Basova, Svetlana Semenova, Howard S. Fox, Timothy Ravasi, Maria Cecilia G. Marcondes
Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection
Rebecca Montacute, Kerry Foley, Ruth Forman, Kathryn Jane Else, Sheena Margaret Cruickshank, Stuart McRae Allan
Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity
Björn Ambrosius, Simon Faissner, Kirsten Guse, Marec von Lehe, Thomas Grunwald, Ralf Gold, Bastian Grewe, Andrew Chan
Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats
Qianpeng Han, Qiongyu Lin, Peixian Huang, Mengmeng Chen, Xin Hu, Hui Fu, Shaoru He, Fengcai Shen, Hongke Zeng, Yiyu Deng
Macrophage and nerve interaction in endometriosis
Jinjie Wu, Hongyu Xie, Shuzhong Yao, Yanchun Liang
Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis
Marta Pulido-Salgado, Jose M. Vidal-Taboada, Gerardo Garcia Diaz-Barriga, Joan Serratosa, Tony Valente, Paola Castillo, Jonathan Matalonga, Marco Straccia, Josep M. Canals, Annabel Valledor, Carme Solà, Josep Saura
MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis
Farideh Talebi, Samira Ghorbani, Wing Fuk Chan, Roobina Boghozian, Farimah Masoumi, Sedigheh Ghasemi, Mohammed Vojgani, Christopher Power, Farshid Noorbakhsh
Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation
Katherine Conant, Stefano Daniele, P. Lorenzo Bozzelli, Tsion Abdi, Amanda Edwards, Arek Szklarczyk, India Olchefske, David Ottenheimer, Kathleen Maguire-Zeiss
Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis
Shailender Singh, Tobias Dallenga, Anne Winkler, Shanu Roemer, Brigitte Maruschak, Heike Siebert, Wolfgang Brück, Christine Stadelmann
Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy
Mohan S. Maddur, Emmanuel Stephen-Victor, Mrinmoy Das, Praveen Prakhar, Varun K. Sharma, Vikas Singh, Magalie Rabin, Jamma Trinath, Kithiganahalli N. Balaji, Francis Bolgert, Jean-Michel Vallat, Laurent Magy, Srini V. Kaveri, Jagadeesh Bayry
The Alzheimer’s disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway
Charlotte Jendresen, Vibeke Årskog, Michael R. Daws, Lars N. G. Nilsson
Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes
Vincent R. Parillaud, Guillaume Lornet, Yann Monnet, Anne-Laure Privat, Andrei T. Haddad, Vanessa Brochard, Amaury Bekaert, Camille Baudesson de Chanville, Etienne C. Hirsch, Christophe Combadière, Stéphane Hunot, Christian S. Lobsiger
Development of a model of Saint Louis encephalitis infection and disease in mice
Rafael Elias Marques, Juliana L. Del Sarto, Rebeca P. F. Rocha, Giovanni F. Gomes, Allysson Cramer, Milene A. Rachid, Danielle G. Souza, Maurício L. Nogueira, Mauro M. Teixeira
Lymphocytes have a role in protection, but not in pathogenesis, during La Crosse Virus infection in mice
Clayton W. Winkler, Lara M. Myers, Tyson A. Woods, Aaron B. Carmody, Katherine G. Taylor, Karin E. Peterson
Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response
Qing Cai, Yuanyuan Li, Gang Pei
Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model
Simone Vodret, Giulia Bortolussi, Jana Jašprová, Libor Vitek, Andrés F. Muro
NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury
James P. Barrett, Rebecca J. Henry, Sonia Villapol, Bogdan A. Stoica, Alok Kumar, Mark P. Burns, Alan I. Faden, David J. Loane
Activation of FXR pathway does not alter glial cell function
Stefanie Albrecht, Ann-Katrin Fleck, Ina Kirchberg, Stephanie Hucke, Marie Liebmann, Luisa Klotz, Tanja Kuhlmann
Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo
Dan Li, Nan Liu, Hai-Hua Zhao, Xu Zhang, Hitoshi Kawano, Lu Liu, Liang Zhao, Hong-Peng Li
Amelioration of experimental autoimmune encephalomyelitis by clozapine is not associated with defective CD4 T cell responses
Pirooz Zareie, Bronwen Connor, Anne Camille La Flamme
In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study
Teruyo Hosoya, Dai Fukumoto, Takeharu Kakiuchi, Shingo Nishiyama, Shigeyuki Yamamoto, Hiroyuki Ohba, Hideo Tsukada, Takatoshi Ueki, Kohji Sato, Yasuomi Ouchi
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat
Fan Liu, Zhiyao Wang, Yue Qiu, Min Wei, Chunyan Li, Yikuan Xie, Le Shen, Yuguang Huang, Chao Ma
Atypical periodic alternating nystagmus responding to high-dose intravenous immunoglobulins: a case report
Herminia Argente-Escrig, Luis Bataller, Claudio Krstulovic Roa, Vanesa Pérez Guillén, Herminio Perez Garrigues, Bonaventura Casanova Estruch
Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairment
Sanjay R. Mehta, Josué Pérez-Santiago, Todd Hulgan, Tyler R. C. Day, Jill Barnholtz-Sloan, Haley Gittleman, Scott Letendre, Ronald Ellis, Robert Heaton, Stephanie Patton, Jesse D. Suben, Donald Franklin, Debralee Rosario, David B. Clifford, Ann C. Collier, Christina M. Marra, Benjamin B. Gelman, Justin McArthur, Allen McCutchan, Susan Morgello, David Simpson, James Connor, Igor Grant, Asha Kallianpur
Cytokine cascades induced by mechanical trauma injury alter voltage-gated sodium channel activity in intact cortical neurons
Weiqiang Chen, Jiangtao Sheng, Jingfang Guo, Guoyi Peng, Jinfang Hong, Bingbing Li, Xiaoxuan Chen, Kangsheng Li, Shousen Wang
Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression
Hai-Jiao Liu, Xiu-Xiu Pan, Bing-Qian Liu, Xuan Gui, Liang Hu, Chun-Yi Jiang, Yuan Han, Yi-Xin Fan, Yu-Lin Tang, Wen-Tao Liu
Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
Zhengqiu Zhou, Adam D. Bachstetter, Claudia B. Späni, Saktimayee M. Roy, D. Martin Watterson, Linda J. Van Eldik
Microglia activation is essential for BMP7-mediated retinal reactive gliosis
Subramanian Dharmarajan, Debra L. Fisk, Christine M. Sorenson, Nader Sheibani, Teri L. Belecky-Adams
Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
E. Soemirien Kasanmoentalib, Mercedes Valls Seron, Bart Ferwerda, Michael W. Tanck, Aeilko H. Zwinderman, Frank Baas, Arie van der Ende, William J. Schwaeble, Matthijs C. Brouwer, Diederik van de Beek
Diffusion MRI quantifies early axonal loss in the presence of nerve swelling
Tsen-Hsuan Lin, Chia-Wen Chiang, Carlos J. Perez-Torres, Peng Sun, Michael Wallendorf, Robert E. Schmidt, Anne H. Cross, Sheng-Kwei Song
The involvement of mast cells in the irinotecan-induced enteric neurons loss and reactive gliosis
Ludmila T. Nogueira, Deiziane V. S. Costa, Antoniella S. Gomes, Conceição S. Martins, Angeline M. H. P. Silva, Juliana M. Coelho-Aguiar, Patrícia Castelucci, Roberto C. P. Lima-Júnior, Renata F. C. Leitão, Vivaldo Moura-Neto, Gerly A. C. Brito
Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring
Billy Vuong, Gary Odero, Stephanie Rozbacher, Mackenzie Stevenson, Stephanie M. Kereliuk, Troy J. Pereira, Vernon W. Dolinsky, Tiina M. Kauppinen
Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion
Yoshiki Hase, Lucinda Craggs, Mai Hase, William Stevenson, Janet Slade, Dianne Lopez, Rubin Mehta, Aiqing Chen, Di Liang, Arthur Oakley, Masafumi Ihara, Karen Horsburgh, Raj N. Kalaria
The PD-1: PD-L1 pathway promotes development of brain-resident memory T cells following acute viral encephalitis
Sujata Prasad, Shuxian Hu, Wen S. Sheng, Priyanka Chauhan, Amar Singh, James R. Lokensgard
Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol
Pallavi Shrivastava, Miguel A. Cabrera, Lucy G. Chastain, Nadka I. Boyadjieva, Shaima Jabbar, Tina Franklin, Dipak K. Sarkar
Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo
Nicholas C. Woodward, Morgan C. Levine, Amin Haghani, Farimah Shirmohammadi, Arian Saffari, Constantinos Sioutas, Todd E. Morgan, Caleb E. Finch
Adiponectin levels in the serum and cerebrospinal fluid of amyotrophic lateral sclerosis patients: possible influence on neuroinflammation?
Patrizia Bossolasco, Raffaella Cancello, Alberto Doretti, Claudia Morelli, Vincenzo Silani, Lidia Cova
Microglial depletion alters the brain neuroimmune response to acute binge ethanol withdrawal
T. Jordan Walter, Fulton T. Crews
TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase
Kaizhe Wang, Ling Ye, Hongfang Lu, Huili Chen, Yanyan Zhang, Yunlong Huang, Jialin C. Zheng
Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress
Simone Mori, Shuei Sugama, William Nguyen, Tatiana Michel, M. Germana Sanna, Manuel Sanchez-Alavez, Rigo Cintron-Colon, Gianluca Moroncini, Yoshihiko Kakinuma, Pamela Maher, Bruno Conti
Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study
Ryo Yamasaki, Hiroo Yamaguchi, Takuya Matsushita, Takayuki Fujii, Akio Hiwatashi, Jun-ichi Kira
Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/IL-6/synapsin I axis in traumatic brain injury rats
Chung-Ching Chio, Hung-Jung Lin, Yu-Feng Tian, Yu-Chieh Chen, Mao-Tsun Lin, Cheng-Hsien Lin, Ching-Ping Chang, Chien-Chin Hsu
Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation
Nathalia R. V. Dragano, Carina Solon, Albina F. Ramalho, Rodrigo F. de Moura, Daniela S. Razolli, Elisabeth Christiansen, Carlos Azevedo, Trond Ulven, Licio A. Velloso
Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection
Björn Ambrosius, Kalliopi Pitarokoili, Lisa Schrewe, Xiomara Pedreiturria, Jeremias Motte, Ralf Gold
GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma
Pete A. Williams, Catherine E. Braine, Nicole E. Foxworth, Kelly E. Cochran, Simon W. M. John
YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2
Zheng-Yi Li, Yoon Hee Chung, Eun-Joo Shin, Duy-Khanh Dang, Ji Hoon Jeong, Sung Kwon Ko, Seung-Yeol Nah, Tae Gon Baik, Jin Hyeong Jhoo, Wei-Yi Ong, Toshitaka Nabeshima, Hyoung-Chun Kim
Retraction Note to: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats
Jagadeesh Sridhara Rao, Hyung-Wook Kim, Matthew Kellom, Dede Greenstein, Mei Chen, Andrew David Kraft, Gaylia Jean Harry, Stanley Isaac Rapoport, Mireille Basselin
Proteomic analysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response
Antwoine Flowers, Harris Bell-Temin, Ahmad Jalloh, Stanley M. Stevens Jr., Paula C. Bickford
HSYA alleviates secondary neuronal death through attenuating oxidative stress, inflammatory response, and neural apoptosis in SD rat spinal cord compression injury
Jun-peng Pei, Li-hong Fan, Kai Nan, Jia Li, Xiao-qian Dang, Kun-zheng Wang
Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice
Naoki Ito, Eiji Hirose, Tatsuya Ishida, Atsushi Hori, Takayuki Nagai, Yoshinori Kobayashi, Hiroaki Kiyohara, Tetsuro Oikawa, Toshihiko Hanawa, Hiroshi Odaguchi
Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity
Kelly S. Kirkley, Katriana A. Popichak, Maryam F. Afzali, Marie E. Legare, Ronald B. Tjalkens
Sex-dependent treatment of chronic EAE with partial MHC class II constructs
Gil Benedek, Priya Chaudhary, Roberto Meza-Romero, Evan Calkins, Gail Kent, Halina Offner, Dennis Bourdette, Arthur A. Vandenbark
Characteristics of primary rat microglia isolated from mixed cultures using two different methods
Li Lin, Rakhi Desai, Xiaoying Wang, Eng H. Lo, Changhong Xing
Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors
Na Yue, Huijie Huang, Xiaocang Zhu, Qiuqin Han, Yalin Wang, Bing Li, Qiong Liu, Gencheng Wu, Yuqiu Zhang, Jin Yu
A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis
Euan R. O. Allan, Rhiannon I. Campden, Benjamin W. Ewanchuk, Pankaj Tailor, Dale R. Balce, Neil T. McKenna, Catherine J. Greene, Amy L. Warren, Thomas Reinheckel, Robin M. Yates
Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage
Qing Zhao, Xudong Che, Hongxia Zhang, Pianpian Fan, Guanping Tan, Liu Liu, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Yidan Liang, Xiaochuan Sun, Zhaohui He
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation
Suzanne A. B. M. Aarts, Tom T. P. Seijkens, Pascal J. H. Kusters, Susanne M. A. van der Pol, Barbara Zarzycka, Priscilla D. A. M. Heijnen, Linda Beckers, Myrthe den Toom, Marion J. J. Gijbels, Louis Boon, Christian Weber, Helga E. de Vries, Gerry A. F. Nicolaes, Christine D. Dijkstra, Gijs Kooij, Esther Lutgens
LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface
Ø. Salvesen, M. R. Reiten, A. Espenes, M. K. Bakkebø, M. A. Tranulis, C. Ersdal
Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice
Wenhui Qu, Andrea Johnson, Joo Hyun Kim, Abigail Lukowicz, Daniel Svedberg, Marija Cvetanovic
Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy
Ellie Edlmann, Susan Giorgi-Coll, Peter C. Whitfield, Keri L. H. Carpenter, Peter J. Hutchinson
MicroRNA-101a regulates microglial morphology and inflammation
Reiko Saika, Hiroshi Sakuma, Daisuke Noto, Shuhei Yamaguchi, Takashi Yamamura, Sachiko Miyake
Receptor tyrosine kinases play a significant role in human oligodendrocyte inflammation and cell death associated with the Lyme disease bacterium Borrelia burgdorferi
Geetha Parthasarathy, Mario T. Philipp
Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes
Stephanie S. Dusaban, Jerold Chun, Hugh Rosen, Nicole H. Purcell, Joan Heller Brown
B cells do not have a major pathophysiologic role in acute ischemic stroke in mice
Michael K. Schuhmann, Friederike Langhauser, Peter Kraft, Christoph Kleinschnitz
Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder
Sarika Singh, Umar Yazdani, Bharathi Gadad, Sayed Zaman, Linda S. Hynan, Nichole Roatch, Claire Schutte, C. Nathan Marti, Laura Hewitson, Dwight C. German
Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages
Rachita K. Sumbria, Vitaly Vasilevko, Mher Mahoney Grigoryan, Annlia Paganini-Hill, Ronald Kim, David H. Cribbs, Mark J. Fisher
Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system
Nádia Pereira Gonçalves, João Moreira, Diana Martins, Paulo Vieira, Laura Obici, Giampaolo Merlini, Margarida Saraiva, Maria João Saraiva
Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner
S. D. Benusa, N. M. George, B. A. Sword, G. H. DeVries, J. L. Dupree
Regulatory T cells in multiple sclerosis and myasthenia gravis
K. M. Danikowski, S. Jayaraman, B. S. Prabhakar
YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies
Marta Querol-Vilaseca, Martí Colom-Cadena, Jordi Pegueroles, Carla San Martín-Paniello, Jordi Clarimon, Olivia Belbin, Juan Fortea, Alberto Lleó
Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway
Jun Zeng, Yizhao Chen, Rui Ding, Liang Feng, Zhenghao Fu, Shuo Yang, Xinqing Deng, Zhichong Xie, Shizhong Zheng
Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement
Aarti Narang, Fei Qiao, Carl Atkinson, Hong Zhu, Xiaofeng Yang, Liudmila Kulik, V. Michael Holers, Stephen Tomlinson
Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130
Xinlei Wang, Eric B. Miller, Mayank Goswami, Pengfei Zhang, Kaitryn E. Ronning, Sarah J. Karlen, Robert J. Zawadzki, Edward N. Pugh Jr., Marie E. Burns
Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation
Haiying Zhang, Joon Ha Park, Sony Maharjan, Jeong Ae Park, Kyu-Sung Choi, Hyojin Park, Yoonjeong Jeong, Ji Hyeon Ahn, In Hye Kim, Jae-Chul Lee, Jeong Hwi Cho, In-Kyu Lee, Choong Hyun Lee, In Koo Hwang, Young-Myeong Kim, Young-Ger Suh, Moo-Ho Won, Young-Guen Kwon
Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis
S. Hahn, G. Trendelenburg, M. Scharf, Y. Denno, S. Brakopp, B. Teegen, C. Probst, K. P. Wandinger, M. Buttmann, A. Haarmann, F. Szabados, M. vom Dahl, T. Kümpfel, P. Eichhorn, H. Gold, F. Paul, S. Jarius, N. Melzer, W. Stöcker, L. Komorowski
Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells
Chandra M. Menendez, Daniel J. J. Carr
Interleukin-1 receptor type 1 is overexpressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant-induced inflammatory pain
Krisztina Holló, László Ducza, Zoltán Hegyi, Klaudia Dócs, Krisztina Hegedűs, Erzsébet Bakk, Ildikó Papp, Gréta Kis, Zoltán Mészár, Zsuzsanna Bardóczi, Miklós Antal
The increased concentration of macrophage migration inhibitory factor in serum and cerebrospinal fluid of patients with tick-borne encephalitis
Sambor Grygorczuk, Miłosz Parczewski, Renata Świerzbińska, Piotr Czupryna, Anna Moniuszko, Justyna Dunaj, Maciej Kondrusik, Sławomir Pancewicz
Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination
Carsten Tue Berg, Reza Khorooshi, Nasrin Asgari, Trevor Owens
A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation
Srikant Rangaraju, Syed Ali Raza, Andrea Pennati, Qiudong Deng, Eric B. Dammer, Duc Duong, Michael W. Pennington, Malu G. Tansey, James J. Lah, Ranjita Betarbet, Nicholas T. Seyfried, Allan I. Levey
Evidence for an early innate immune response in the motor cortex of ALS
Javier H. Jara, Barış Genç, Macdonell J. Stanford, Peter Pytel, Raymond P. Roos, Sandra Weintraub, M. Marsel Mesulam, Eileen H. Bigio, Richard J. Miller, P. Hande Özdinler
The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats’ retinal ganglion cells after ischemia and reperfusion injury
Felix Ulbrich, Claus Hagmann, Hartmut Buerkle, Carlos C. Romao, Nils Schallner, Ulrich Goebel, Julia Biermann
Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β
Paul R. Lee, Tory P. Johnson, Sharmilee Gnanapavan, Gavin Giovannoni, Tongguang Wang, Joseph P. Steiner, Marie Medynets, Mark J. Vaal, Valerie Gartner, Avindra Nath
Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia
Min Yin, Zhiying Chen, Yetong Ouyang, Huiyan Zhang, Zhigang Wan, Han Wang, Wei Wu, Xiaoping Yin
Amplification and propagation of interleukin-1β signaling by murine brain endothelial and glial cells
Stephanie M. Krasnow, J. Gabriel Knoll, Santhosh Chakkaramakkil Verghese, Peter R. Levasseur, Daniel L. Marks
CXCL11 production in cerebrospinal fluid distinguishes herpes simplex meningitis from herpes simplex encephalitis
Liza Lind, Marie Studahl, Linn Persson Berg, Kristina Eriksson
The role of microglial P2X7: modulation of cell death and cytokine release
Yingbo He, Natalie Taylor, Lawrence Fourgeaud, Anindya Bhattacharya
MHC class II expression and potential antigen-presenting cells in the retina during experimental autoimmune uveitis
Deborah A. Lipski, Rémi Dewispelaere, Vincent Foucart, Laure E. Caspers, Matthieu Defrance, Catherine Bruyns, François Willermain
Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats
Benjarat Changyaleket, Zhao Zhong Chong, Randal O. Dull, Danop Nanegrungsunk, Haoliang Xu
Activation of cannabinoid receptor type 2 attenuates surgery-induced cognitive impairment in mice through anti-inflammatory activity
Lingling Sun, Rui Dong, Xin Xu, Xi Yang, Mian Peng
Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage
Biqiong Zhang, Yaodong Zhang, Wenning Wu, Tanzhen Xu, Yanyan Yin, Junyan Zhang, Dake Huang, Weizu Li
Ischaemic stroke and the recanalization drug tissue plasminogen activator interfere with antibacterial phagocyte function
Antje Vogelgesang, Claudia Lange, Lara Blümke, Georg Laage, Sarah Rümpel, Sönke Langner, Barbara M. Bröker, Alexander Dressel, Johanna Ruhnau
Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging
Colleen A. Mangold, Benjamin Wronowski, Mei Du, Dustin R. Masser, Niran Hadad, Georgina V. Bixler, Robert M. Brucklacher, Matthew M. Ford, William E. Sonntag, Willard M. Freeman
Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease
Shinji Yamamoto, Kota Yamashina, Masaki Ishikawa, Mari Gotoh, Sosuke Yagishita, Kensuke Iwasa, Kei Maruyama, Kimiko Murakami-Murofushi, Keisuke Yoshikawa
Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury
Xiangrong Chen, Shukai Wu, Chunnuan Chen, Baoyuan Xie, Zhongning Fang, Weipeng Hu, Junyan Chen, Huangde Fu, Hefan He
Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients
Patrice H. Lalive, Mario Kreutzfeldt, Odile Devergne, Imke Metz, Wolfgang Bruck, Doron Merkler, Caroline Pot
TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders
María Pascual, Jorge Montesinos, Sandra Montagud-Romero, Jerónimo Forteza, Marta Rodríguez-Arias, José Miñarro, Consuelo Guerri
Erratum to: The role of PPAR activation during the systemic response to brain injury
Patrick Losey, Emma Ladds, Maud Laprais, Borna Guevel, Laura Burns, Regis Bordet, Daniel C. Anthony
Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury
Raffaela Cipriani, Juan Carlos Chara, Alfredo Rodríguez-Antigüedad, Carlos Matute
Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis
Kathrin Bail, Quirin Notz, Damiano M. Rovituso, Andrea Schampel, Marie Wunsch, Tobias Koeniger, Verena Schropp, Richa Bharti, Claus-Juergen Scholz, Konrad U. Foerstner, Christoph Kleinschnitz, Stefanie Kuerten
Adaptive lymphocyte profiles correlate to brain Aβ burden in patients with mild cognitive impairment
Ann M. Stowe, Sara J. Ireland, Sterling B. Ortega, Ding Chen, Ryan M. Huebinger, Takashi Tarumi, Thomas S. Harris, C. Munro Cullum, Roger Rosenberg, Nancy L. Monson, Rong Zhang
Sensitization of ASIC3 by proteinase-activated receptor 2 signaling contributes to acidosis-induced nociception
Jing Wu, Ting-Ting Liu, Yi-Mei Zhou, Chun-Yu Qiu, Ping Ren, Ming Jiao, Wang-Ping Hu
A translocator protein 18 kDa agonist protects against cerebral ischemia/reperfusion injury
Han-Dong Li, Minshu Li, Elaine Shi, Wei-Na Jin, Kristofer Wood, Rayna Gonzales, Qiang Liu
Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis
Leonie Stolz, Amin Derouiche, Kavi Devraj, Frank Weber, Robert Brunkhorst, Christian Foerch
Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke
Ruimin Ge, Daniel Tornero, Masao Hirota, Emanuela Monni, Cecilia Laterza, Olle Lindvall, Zaal Kokaia
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
Sylvia Torres-Odio, Jana Key, Hans-Hermann Hoepken, Júlia Canet-Pons, Lucie Valek, Bastian Roller, Michael Walter, Blas Morales-Gordo, David Meierhofer, Patrick N. Harter, Michel Mittelbronn, Irmgard Tegeder, Suzana Gispert, Georg Auburger
microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells
Reema Roshan, Ashwani Choudhary, Aksheev Bhambri, Bhawani Bakshi, Tanay Ghosh, Beena Pillai
Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis
Danfeng Xu, Di Lian, Jing Wu, Ying Liu, Mingjie Zhu, Jiaming Sun, Dake He, Ling Li
Erratum to: VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage
Catalina Abad, Bhavaani Jayaram, Laurine Becquet, Yuqi Wang, M. Sue O’Dorisio, James A. Waschek, Yossan-Var Tan
Regulation of inflammation in Japanese encephalitis
Nils Lannes, Artur Summerfield, Luis Filgueira
The chemokine fractalkine (CX3CL1) attenuates H2O2-induced demyelination in cerebellar slices
Sinead A. O’Sullivan, Kumlesh K. Dev
Bioinformatics analysis of glial inflammatory responses to air pollution
Chenyu Li, Wei Jiang, Nina Tang, Yan Xu
Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury
Ramona E. von Leden, Guzal Khayrullina, Kasey E. Moritz, Kimberly R. Byrnes
Inflammatory demyelination alters subcortical visual circuits
Sheila Espírito Santo Araújo, Henrique Rocha Mendonça, Natalie A. Wheeler, Paula Campello-Costa, Kimberle M. Jacobs, Flávia C. A. Gomes, Michael A. Fox, Babette Fuss
Endogenous hydrogen sulphide attenuates NLRP3 inflammasome-mediated neuroinflammation by suppressing the P2X7 receptor after intracerebral haemorrhage in rats
Hengli Zhao, Pengyu Pan, Yang Yang, Hongfei Ge, Weixiang Chen, Jie Qu, Jiantao Shi, Gaoyu Cui, Xin Liu, Hua Feng, Yujie Chen
Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease
Lori N. Eidson, George T. Kannarkat, Christopher J. Barnum, Jianjun Chang, Jaegwon Chung, Chelsea Caspell-Garcia, Peggy Taylor, Brit Mollenhauer, Michael G. Schlossmacher, Larry Ereshefsky, Mark Yen, Catherine Kopil, Mark Frasier, Kenneth Marek, Vicki S. Hertzberg, Malú G. Tansey
Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies
José Carlos Rivera, Mari Holm, Dordi Austeng, Tora Sund Morken, Tianwei (Ellen) Zhou, Alexandra Beaudry-Richard, Estefania Marin Sierra, Olaf Dammann, Sylvain Chemtob
Responses of rat and mouse primary microglia to pro- and anti-inflammatory stimuli: molecular profiles, K+ channels and migration
Doris Lam, Starlee Lively, Lyanne C. Schlichter
Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury
Xin Xu, Weiwei Gao, Shiqi Cheng, Dongpei Yin, Fei Li, Yingang Wu, Dongdong Sun, Shuai Zhou, Dong Wang, Yongqiang Zhang, Rongcai Jiang, Jianning Zhang
Prophylactic inhibition of neutrophil elastase prevents the development of chronic neuropathic pain in osteoarthritic mice
Milind M. Muley, Eugene Krustev, Allison R. Reid, Jason J. McDougall
Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats
Dongshu Du, Li Hu, Jiaxiang Wu, Qin Wu, Wenjing Cheng, Yuhong Guo, Ruijuan Guan, Yahui Wang, Xingxin Chen, Xanxia Yan, Danian Zhu, Jijiang Wang, Shutian Zhang, Yanfang Guo, Chunmei Xia
Docosahexaenoic acid-containing choline phospholipid modulates LPS-induced neuroinflammation in vivo and in microglia in vitro
Célia Fourrier, Julie Remus-Borel, Andrew D. Greenhalgh, Michel Guichardant, Nathalie Bernoud-Hubac, Michel Lagarde, Corinne Joffre, Sophie Layé
Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis
S. Jarius, F.B. König, I. Metz, K. Ruprecht, F. Paul, W. Brück, B. Wildemann
Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS
Tjalf Ziemssen, Hayrettin Tumani, Tony Sehr, Katja Thomas, Friedemann Paul, Nils Richter, Emil Samara, Ofer Spiegelstein, Ella Sorani, Oren Bar-Ilan, Dorit Mimrod, Liat Hayardeny
Cerebrospinal fluid CXCL13 as a diagnostic marker of neuroborreliosis in children: a retrospective case-control study
M. M. Remy, N. Schöbi, L. Kottanattu, S. Pfister, A. Duppenthaler, F. Suter-Riniker
Selective suppression of the JNK-MMP2/9 signal pathway by tetramethylpyrazine attenuates neuropathic pain in rats
Lai Jiang, Cai-Long Pan, Chao-Yu Wang, Bing-Qian Liu, Yuan Han, Liang Hu, Lei Liu, Yang Yang, Jun-Wei Qu, Wen-Tao Liu
Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer’s disease with cerebrovascular disease
Xavier Gallart-Palau, Aida Serra, Benjamin Sian Teck Lee, Xue Guo, Siu Kwan Sze
Arginine vasopressin altered the expression of monocarboxylate transporters in cultured astrocytes isolated from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats
Kazuo Yamagata, Natsumi Takahashi, Nozomi Akita, Toru Nabika
Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis
Volodymyr Gerzanich, Tapas K. Makar, Poornachander Reddy Guda, Min Seong Kwon, Jesse A. Stokum, Seung Kyoon Woo, Svetlana Ivanova, Alexander Ivanov, Rupal I. Mehta, Alexandra Brooke Morris, Joseph Bryan, Christopher T. Bever, J. Marc Simard
Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype
Milena Fioravante, Bruna Bombassaro, Albina F. Ramalho, Nathalia R. Dragano, Joseane Morari, Carina Solon, Natalia Tobar, Celso D. Ramos, Licio A. Velloso
Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations
Joana Prata, Susana G. Santos, Maria Inês Almeida, Rui Coelho, Mário A. Barbosa
Functional changes in hippocampal synaptic signaling in offspring survivors of a mouse model of intrauterine inflammation
Melissa H. Kelley, Wendy W. Wu, Jun Lei, Michael McLane, Han Xie, Kyle D. Hart, Leonardo Pereira, Irina Burd, James Maylie
Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina
José Carlos Rivera, Baraa Noueihed, Ankush Madaan, Isabelle Lahaie, Jingyi Pan, Jaques Belik, Sylvain Chemtob
Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu
Andrea Alice Silva, Rafael Rodrigues Silva, Daniel Gibaldi, Rafael Meyer Mariante, Jessica Brandão dos Santos, Isabela Resende Pereira, Otacílio Cruz Moreira, Joseli Lannes-Vieira
Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation
Amila Omeragic, Md Tozammel Hoque, U-yeong Choi, Reina Bendayan
Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation
Anna Hammer, Anne Schliep, Stefanie Jörg, Aiden Haghikia, Ralf Gold, Markus Kleinewietfeld, Dominik N. Müller, Ralf A. Linker
Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats
Juan Niu, Dujuan Huang, Rui Zhou, MingXia Yue, Tao Xu, Junna Yang, Li He, Hong Tian, XiaoHong Liu, Junwei Zeng
Fluoxetine-enhanced autophagy ameliorates early brain injury via inhibition of NLRP3 inflammasome activation following subarachnoid hemorrhage in rats
Jian-ru Li, Hang-zhe Xu, Sheng Nie, Yu-cong Peng, Lin-Feng Fan, Zhi-jiang Wang, Cheng Wu, Feng Yan, Jing-yin Chen, Chi Gu, Chun Wang, Jing-sen Chen, Lin Wang, Gao Chen
Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke
Shuang Chen, Zhiping Dong, Man Cheng, Yaqian Zhao, Mengying Wang, Na Sai, Xuan Wang, Huan Liu, Guowei Huang, Xumei Zhang
Using blood cytokine measures to define high inflammatory biotype of schizophrenia and schizoaffective disorder
Danny Boerrigter, Thomas W. Weickert, Rhoshel Lenroot, Maryanne O’Donnell, Cherrie Galletly, Dennis Liu, Martin Burgess, Roxanne Cadiz, Isabella Jacomb, Vibeke S. Catts, Stu G. Fillman, Cynthia Shannon Weickert
Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons
Hyunjung Baek, Hyo Jung Shin, Jwa-Jin Kim, Nara Shin, Sena Kim, Min-Hee Yi, Enji Zhang, Jinpyo Hong, Joon Won Kang, Yonghyun Kim, Cuk-Seong Kim, Dong Woon Kim
Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice
Mengmeng Li, Chenli Li, Hanjie Yu, Xiongxiong Cai, Xinbei Shen, Xin Sun, Jinting Wang, Yanhua Zhang, Chuang Wang
Increased frequency of IL-6-producing non-classical monocytes in neuromyelitis optica spectrum disorder
Byung Soo Kong, Yeseul Kim, Ga Young Kim, Jae-Won Hyun, Su-Hyun Kim, Aeran Jeong, Ho Jin Kim
Anti-inflammatory effects of astroglial α7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-κB pathway and activation of the Nrf2 pathway
Hiral Patel, Jessica McIntire, Sarah Ryan, Anthone Dunah, Ralph Loring
Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study
Andreas Pikwer, Markus Castegren, Sijal Namdar, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson
αVβ3 Integrin regulates astrocyte reactivity
Raúl Lagos-Cabré, Alvaro Alvarez, Milene Kong, Francesca Burgos-Bravo, Areli Cárdenas, Edgardo Rojas-Mancilla, Ramón Pérez-Nuñez, Rodrigo Herrera-Molina, Fabiola Rojas, Pascal Schneider, Mario Herrera-Marschitz, Andrew F. G. Quest, Brigitte van Zundert, Lisette Leyton
Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress
Feroz Akhtar, Christopher A. Rouse, Gabriel Catano, Marcus Montalvo, Sarah L. Ullevig, Reto Asmis, Kusum Kharbanda, Shivani K. Maffi
The contribution of the acute phase response to the pathogenesis of relapse in chronic-relapsing experimental autoimmune encephalitis models of multiple sclerosis
Silvy Mardiguian, Emma Ladds, Roberta Turner, Hazel Shepherd, Sandra J. Campbell, Daniel C. Anthony
Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats
Hidetsugu Maekawa, Yoshiteru Tada, Kenji Yagi, Takeshi Miyamoto, Keiko T. Kitazato, Masaaki Korai, Junichiro Satomi, Tomoki Hashimoto, Shinji Nagahiro
Agonists for G-protein-coupled receptor 84 (GPR84) alter cellular morphology and motility but do not induce pro-inflammatory responses in microglia
Li Wei, Kyohei Tokizane, Hiroyuki Konishi, Hua-Rong Yu, Hiroshi Kiyama
Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation
Wen Fu, Vlatka Vukojevic, Aarti Patel, Rania Soudy, David MacTavish, David Westaway, Kamaljit Kaur, Valeri Goncharuk, Jack Jhamandas
Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures
Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim, Ran Lee
Withania somnifera as a potential candidate to ameliorate high fat diet-induced anxiety and neuroinflammation
Taranjeet Kaur, Gurcharan Kaur
Erythropoietin reduces experimental autoimmune encephalomyelitis severity via neuroprotective mechanisms
M. Moransard, M. Bednar, K. Frei, M. Gassmann, O. O. Ogunshola
The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke
Mengni Yi, Tianjiao Wei, Yanxia Wang, Qin Lu, Gaoxian Chen, Xiaoling Gao, Herbert M. Geller, Hongzhuan Chen, Zhihua Yu
Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties
Chittappen K. Prajeeth, Julius Kronisch, Reza Khorooshi, Benjamin Knier, Henrik Toft-Hansen, Viktoria Gudi, Stefan Floess, Jochen Huehn, Trevor Owens, Thomas Korn, Martin Stangel
Elevated microRNA-129-5p level ameliorates neuroinflammation and blood-spinal cord barrier damage after ischemia-reperfusion by inhibiting HMGB1 and the TLR3-cytokine pathway
Xiao-Qian Li, Feng-Shou Chen, Wen-Fei Tan, Bo Fang, Zai-Li Zhang, Hong Ma
Correction to: the disruption of mitochondrial axonal transport is an early event in neuroinflammation
Oihana Errea, Beatriz Moreno, Alba Gonzalez-Franquesa, Pablo M. Garcia-Roves, Pablo Villoslada
Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice
Wu Jiang, Maoqiang Li, Fan He, Shaobo Zhou, Liulong Zhu
Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination
Patrick Peschl, Kathrin Schanda, Bleranda Zeka, Katherine Given, Denise Böhm, Klemens Ruprecht, Albert Saiz, Andreas Lutterotti, Kevin Rostásy, Romana Höftberger, Thomas Berger, Wendy Macklin, Hans Lassmann, Monika Bradl, Jeffrey L. Bennett, Markus Reindl
Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
Pierre J. Doyen, Maxime Vergouts, Amandine Pochet, Nathalie Desmet, Sabien van Neerven, Gary Brook, Emmanuel Hermans
Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance
Wen-Jun Su, Wei Peng, Hong Gong, Yun-Zi Liu, Yi Zhang, Yong-Jie Lian, Zhi-Yong Cao, Ran Wu, Lin-Lin Liu, Bo Wang, Yun-Xia Wang, Chun-Lei Jiang
Lidocaine alleviates morphine tolerance via AMPK-SOCS3-dependent neuroinflammation suppression in the spinal cord
Yan Zhang, Gao-Jian Tao, Liang Hu, Jie Qu, Yuan Han, Guangqin Zhang, Yanning Qian, Chun-Yi Jiang, Wen-Tao Liu
Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala
Elaine O’Loughlin, Janelle M. P. Pakan, Deniz Yilmazer-Hanke, Kieran W. McDermott
The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells
Xiao-Fan Hu, Xiao-Tao He, Kai-Xiang Zhou, Chen Zhang, Wen-Jun Zhao, Ting Zhang, Jin-Lian Li, Jian-Ping Deng, Yu-Lin Dong
Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis
Ilias Masouris, Matthias Klein, Susanne Dyckhoff, Barbara Angele, H. W. Pfister, Uwe Koedel
DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
Henna Martiskainen, Kaisa M. A. Paldanius, Teemu Natunen, Mari Takalo, Mikael Marttinen, Stina Leskelä, Nadine Huber, Petra Mäkinen, Enni Bertling, Hiramani Dhungana, Mikko Huuskonen, Paavo Honkakoski, Pirta Hotulainen, Kirsi Rilla, Jari Koistinaho, Hilkka Soininen, Tarja Malm, Annakaisa Haapasalo, Mikko Hiltunen
Chronic cerebral hypoperfusion induces post-stroke dementia following acute ischemic stroke in rats
Dong Bin Back, Kyoung Ja Kwon, Dong-Hee Choi, Chan Young Shin, Jongmin Lee, Seol-Heui Han, Hahn Young Kim
Endothelial α6β4 integrin protects during experimental autoimmune encephalomyelitis-induced neuroinflammation by maintaining vascular integrity and tight junction protein expression
Jennifer V. Welser, Sebok K. Halder, Ravi Kant, Amin Boroujerdi, Richard Milner
Microglial dynamics after axotomy-induced retinal ganglion cell death
Francisco M. Nadal-Nicolás, Manuel Jiménez-López, Manuel Salinas-Navarro, Paloma Sobrado-Calvo, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice
J. Gabriel Knoll, Stephanie M. Krasnow, Daniel L. Marks
EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment
Yatao Yin, Shuwei Qiu, Xiangpen Li, Bo Huang, Yun Xu, Ying Peng
Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery
Xi Xin, Fei Xin, Xuguang Chen, Qi Zhang, Yanan Li, Shuping Huo, Chongfu Chang, Qiujun Wang
Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation
Meetu Wadhwa, Amit Prabhakar, Koushik Ray, Koustav Roy, Punita Kumari, Prabhash Kumar Jha, Krishna Kishore, Sanjeev Kumar, Usha Panjwani
Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity
Yang Liu, Xin Xie, Li-Ping Xia, Hong Lv, Fan Lou, Yan Ren, Zhi-Yi He, Xiao-Guang Luo
Anti-NF155 chronic inflammatory demyelinating polyradiculoneuropathy strongly associates to HLA-DRB15
Laura Martinez-Martinez, Ma. Cinta Lleixà, Gemma Boera-Carnicero, Andrea Cortese, Jérôme Devaux, Ana Siles, Yusuf Rajabally, Alicia Martinez-Piñeiro, Alejandra Carvajal, Julio Pardo, Emilien Delmont, Shahram Attarian, Jordi Diaz-Manera, Ilaria Callegari, Enrico Marchioni, Diego Franciotta, Luana Benedetti, Guiseppe Lauria, Oscar de la Calle Martin, Cándido Juárez, Isabel Illa, Luis Querol
Selective depletion of microglial progranulin in mice is not sufficient to cause neuronal ceroid lipofuscinosis or neuroinflammation
Terri L. Petkau, Natalia Kosior, Kathleen de Asis, Colúm Connolly, Blair R. Leavitt
Correction to: Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures
Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim, Ran Lee
Humoral response in experimental autoimmune encephalomyelitis targets neural precursor cells in the central nervous system of naive rodents
Evangelia Kesidou, Olga Touloumi, Roza Lagoudaki, Evangelia Nousiopoulou, Paschalis Theotokis, Kyriaki-Nepheli Poulatsidou, Marina Boziki, Evangelia Kofidou, Nickoleta Delivanoglou, Fani Minti, Georgios Hadjigeorgiou, Nikolaos Grigoriadis, Constantina Simeonidou
Blocking ATP-sensitive potassium channel alleviates morphine tolerance by inhibiting HSP70-TLR4-NLRP3-mediated neuroinflammation
Jie Qu, Xue-You Tao, Peng Teng, Yan Zhang, Ci-Liang Guo, Liang Hu, Yan-Ning Qian, Chun-Yi Jiang, Wen-Tao Liu
MicroRNA expression changes in association with changes in interleukin-1ß/interleukin10 ratios produced by monocytes in autism spectrum disorders: their association with neuropsychiatric symptoms and comorbid conditions (observational study)
Harumi Jyonouchi, Lee Geng, Deanna L. Streck, James J. Dermody, Gokce A. Toruner
Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage
Chun-Hu Wu, Song-Kun Shyue, Tai-Ho Hung, Shin Wen, Chao-Chang Lin, Che-Feng Chang, Szu-Fu Chen
Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner
Lin Sun, Man Li, Xun Ma, Haoyu Feng, Junlai Song, Cong Lv, Yajun He
Novel pathomechanisms in inflammatory neuropathies
David Schafflick, Bernd C. Kieseier, Heinz Wiendl, Gerd Meyer zu Horste
Mild endoplasmic reticulum stress ameliorates lipopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization
Yi-wei Wang, Qin Zhou, Xiang Zhang, Qing-qing Qian, Jia-wen Xu, Peng-fei Ni, Yan-ning Qian
Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress
Dan Zhao, Xulin Xu, Linna Pan, Wei Zhu, Xiaopei Fu, Lianjun Guo, Qing Lu, Jian Wang
Regulator of oligodendrocyte maturation, miR-219, a potential biomarker for MS
Ilona B. Bruinsma, Marie van Dijk, Claire Bridel, Timothy van de Lisdonk, Sanne Q. Haverkort, Tessel F. Runia, Lawrence Steinman, Rogier Q. Hintzen, Joep Killestein, Marcel M. Verbeek, Charlotte E. Teunissen, Brigit A. de Jong
Selective proliferative response of microglia to alternative polarization signals
Giovanna Pepe, Marcella De Maglie, Lucia Minoli, Alessandro Villa, Adriana Maggi, Elisabetta Vegeto
Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation
Hiramani Dhungana, Mikko T. Huuskonen, Merja Jaronen, Sighild Lemarchant, Humair Ali, Velta Keksa-Goldsteine, Gundars Goldsteins, Katja M. Kanninen, Jari Koistinaho, Tarja Malm
Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection
Charles L. Howe, Reghann G. LaFrance-Corey, Emma N. Goddery, Renee K. Johnson, Kanish Mirchia
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome
Pei Jiang, Yujin Guo, Ruili Dang, Mengqi Yang, Dehua Liao, Huande Li, Zhen Sun, Qingyan Feng, Pengfei Xu
Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway
Ji-Hyun Park, Young Ho Seo, Jung-Hee Jang, Chul-Ho Jeong, Sooyeun Lee, Byoungduck Park
Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes
Gabriel Gustafsson, Veronica Lindström, Jinar Rostami, Eva Nordström, Lars Lannfelt, Joakim Bergström, Martin Ingelsson, Anna Erlandsson
Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion
Alizé Proust, Corinne Barat, Mathieu Leboeuf, Jean Drouin, Michel J. Tremblay
DNA repair protein APE1 is involved in host response during pneumococcal meningitis and its expression can be modulated by vitamin B6
Leonam G. Coutinho, Ana Helena Sales de Oliveira, Matthias Witwer, Stephen L. Leib, Lucymara F. Agnez-Lima
Distinct cytokine patterns may regulate the severity of neonatal asphyxia—an observational study
Anna Bajnok, László Berta, Csaba Orbán, Gábor Veres, Dénes Zádori, Hajnalka Barta, Ünőke Méder, László Vécsei, Tivadar Tulassay, Miklós Szabó, Gergely Toldi
Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P
Amanda R. Burmeister, M. Brittany Johnson, Vinita S. Chauhan, Megan J. Moerdyk-Schauwecker, Ada D. Young, Ian D. Cooley, Alejandra N. Martinez, Geeta Ramesh, Mario T. Philipp, Ian Marriott
AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity
Soraya Wilke Saliba, Ariel R. Marcotegui, Ellen Fortwängler, Johannes Ditrich, Juan Carlos Perazzo, Eduardo Muñoz, Antônio Carlos Pinheiro de Oliveira, Bernd L. Fiebich
Dimethylarginines in patients with intracerebral hemorrhage: association with outcome, hematoma enlargement, and edema
Hans Worthmann, Na Li, Jens Martens-Lobenhoffer, Meike Dirks, Ramona Schuppner, Ralf Lichtinghagen, Jan T. Kielstein, Peter Raab, Heinrich Lanfermann, Stefanie M. Bode-Böger, Karin Weissenborn
Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models
Yan Feng, Shiwei Liao, Changjuan Wei, Dongmei Jia, Kristofer Wood, Qiang Liu, Xiaoying Wang, Fu-Dong Shi, Wei-Na Jin
Macrophages in trigeminal ganglion contribute to ectopic mechanical hypersensitivity following inferior alveolar nerve injury in rats
Dulguun Batbold, Masamichi Shinoda, Kuniya Honda, Akihiko Furukawa, Momoko Koizumi, Ryuta Akasaka, Satoshi Yamaguchi, Koichi Iwata
EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination
Aleksandra Rutkowska, Andreas W. Sailer, Kumlesh K. Dev
Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia
Pooja-Shree Mishra, K. Vijayalakshmi, A. Nalini, T. N. Sathyaprabha, B. W. Kramer, Phalguni Anand Alladi, T. R. Raju
Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome
Elizabeth Nance, Siva P. Kambhampati, Elizabeth S. Smith, Zhi Zhang, Fan Zhang, Sarabdeep Singh, Michael V. Johnston, Rangaramanujam M. Kannan, Mary E. Blue, Sujatha Kannan
Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype
I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. F. Graier, D. Kratky, E. Malle, W. Sattler
Prenatal alcohol exposure is a risk factor for adult neuropathic pain via aberrant neuroimmune function
Joshua J. Sanchez, Shahani Noor, Suzy Davies, Daniel Savage, Erin D. Milligan
γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice
Xiaoli Zhang, Eridan Rocha-Ferreira, Tao Li, Regina Vontell, Darakhshan Jabin, Sha Hua, Kai Zhou, Arshed Nazmi, Anna-Maj Albertsson, Kristina Sobotka, Joakim Ek, Claire Thornton, Henrik Hagberg, Carina Mallard, Jianmei W. Leavenworth, Changlian Zhu, Xiaoyang Wang
Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia
Zheng Fan, Zhigang Liang, Hui Yang, Yuting Pan, Yan Zheng, Xiaomin Wang
Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?
Claudia Sestito, John J. P. Brevé, Marja C. J. A. van Eggermond, Joep Killestein, Charlotte E. Teunissen, Joram van Rossum, Micha M. M. Wilhelmus, Benjamin Drukarch, Peter J. van den Elsen, Anne-Marie van Dam
Donepezil suppresses intracellular Ca2+ mobilization through the PI3K pathway in rodent microglia
Yoshinori Haraguchi, Yoshito Mizoguchi, Masahiro Ohgidani, Yoshiomi Imamura, Toru Murakawa-Hirachi, Hiromi Nabeta, Hiroshi Tateishi, Takahiro A. Kato, Akira Monji
Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis
Wissam Beaino, Bieneke Janssen, Gijs Kooij, Susanne M. A. van der Pol, B. van Het Hof, Jack van Horssen, Albert D. Windhorst, Helga E. de Vries
Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures
Nathaly Espitia Pinzón, John J. P. Brevé, John G. J. M. Bol, Benjamin Drukarch, Wia Baron, Anne-Marie van Dam
Inflammatory dysregulation of monocytes in pediatric patients with obsessive-compulsive disorder
Natalia Rodríguez, Astrid Morer, E. Azucena González-Navarro, Carles Serra-Pages, Daniel Boloc, Teresa Torres, Susana García-Cerro, Sergi Mas, Patricia Gassó, Luisa Lázaro
Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain
Alyssa L. Pedersen, Colin J. Saldanha