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Comparative Clinical Pathology OnlineFirst articles

04-06-2024 | Original Article

Taurine and protocatechuic acid attenuate Vincristine sulphate-induced bone marrow, liver and intestinal injuries via anti-oxidative, anti-inflammatory and anti-apoptotic activities

Chemotherapy with Vincristine (Vcr) is often compromised by undesirable gastrointestinal, myeloid and hepatic effects. In this study, we evaluated and compared the efficacy of taurine (Tau) and/or protocatechuic acid (Pca) in alleviating …

Authors:
Akinleye Stephen Akinrinde, Jadesola Juliana Ajao, Ademola Adetokunbo Oyagbemi, Olufunke Eunice Ola-Davies

03-06-2024 | Original Article

Performance, haematology, and blood chemistry of broiler chickens fed diets having reduced energy and protein with or without baker’s yeast (Saccharomyces cerevisiae)

The role of baker’s yeast in poultry performance when fed a standard diet is well known. However, its effect on broiler chickens fed low-nutrient diets is lacking in literature. The aim of this study is to evaluate the performance, haematology …

Authors:
E. U. Ahiwe, O. E. Kadurumba, I. P. Ogbuewu, I. Ejiofor, T. C. Iwuji, V. U. Odoemelam, I. F. Etuk, O. O. Emenalom

31-05-2024 | Original Article

Passive immunity transfer in bovine calves: analysis methods and their correlations with maternal and colostral parameters

Failure of passive transfer of immunity (FPT) is a prevalent concern in veterinary practice and can be assessed through various methodologies. Hence, the aim of this study was to assess different methodologies for determining FPT in calves, along …

Authors:
Pedro Paulo Arcanjo Lima, Jefferson Filgueira Alcindo, Joyce Cristina Ripi Fioruci, Letícia Ramos Costa, Paula Lima de Oliveira, Maria Rachel Melo Bosculo, Thiago Luís Magnani Grassi, Elisa Helena Giglio Ponsano, Claudia Yumi Matsubara Rodrigues Ferreira, Breno Fernando Martins de Almeida

29-05-2024 | Estradiol | Original Article

Oleic acid induces mitochondrial-mediated cell death via mPT pore and protects against estradiol benzoate-induced endometrial hyperplasia in female Wistar rats

Endometrial hyperplasia (EH) is a female gynecological disorder which occurs in women of reproductive age. It has been attributed to excessive exposure to estrogen and this has been linked to a loss of apoptotic signaling, thereby leading to …

Authors:
Adeola Oluwakemi Olowofolahan, Oluwasanmi Olayinka Aina, Olufunso Olabode Olorunsogo

20-05-2024 | Original Article

Use of homeopathy in feeding piglets as an alternative to reduce fighting behavior in the nursery phase: effects on production and hematological, metabolic, and oxidative variables

This study aimed to determine whether using a homeopathic agent would improve the behavior, growth performance, redox status, and neuroimmune pathways of the central nervous system in weaned pigs. A total of 108 pigs in the nursery phase were …

Authors:
Isadora Zago, Gabriela M. Galli, Cássio A. Ficagna, Emerson Zatti, Lara Tarasconi, Maksuel G. D’Vitt, Diovani Paiano, Aleksandro S. da Silva

18-05-2024 | Metformin | Original Article

Myocardial complications induced by hypothyroidism in rats: effects of metformin and alpha lipoic acid

Hypothyroidism has adverse effects on heart metabolism and functions including reduced heart rate, cardiac output and cardiac contractility. The therapeutic effects of alpha lipoic acid (LA) and metformin (MET) against hypothyroidism-induced …

Authors:
Yasser A. Khadrawy, Eman N. Hosny, Howida S. Abou-Seif, Fatma A. Morsy, Hussein G. Sawie

06-05-2024 | Probiotics | Original Article

Hemato-biochemical and histopathological effects of blue-green algae, probiotic, and antibiotic in Cyprinus carpio L

Feed additives in fish rations improve feed efficiency, increase the growth rate of fisheries, and play a significant role in the immunoprophylactic control of infections in aquaculture. This study aims to evaluate the hematological and …

Authors:
Shahbaa Khalil AL-Taee, Fawwaz Fadhil Ali, Nidhal Tahseen Taha AL-Taee, Mahmoud Ahmad Mohammad, Donea Abdulrazak Abdullah, Shola David Ola-Fadunsin

04-05-2024 | Salpingitis | Case Report

Unilateral hyperplasia of the oviduct in a dog with a history of normal reproduction

A 2.5-year-old mixed-breed female dog with a history of normal reproduction underwent ovariohysterectomy. A large, asymmetrical, reddish mass about 12.5 × 9 cm was discovered between the uterus and left ovary in the location of the left oviduct.

Authors:
Amirreza Hashemi, Asghar Mogheiseh, Nasrollah Ahmadi, Amin Bigham-Sadegh, Arian Rajabi

29-04-2024 | Neonatal Screening | Original Article

Instability of acylcarnitine and amino acids in dried blood spots preserved at various temperatures: the impact on retrospective analysis of inborn errors of metabolism biomarkers

Stored dried blood spots (DBSs) give significant specimens for retrospective detection of inborn errors of metabolisms (IEM) including for validation studies through newborn screening (NBS) programs. Inborn errors of metabolisms have severe …

Authors:
Zaed A. Asiri, Zahir H. Alshehry, Mohammed Zourob, Maram S. Alharbi, Haitham M. Al Shomar, Abeer AlGadhi, Abdullah S. Alshehri

26-04-2024 | Hypothyroidism | Correction

Correction to: The effects of wild pistachio oil on serum leptin, thyroid hormones, and lipid profile in female rats with experimental hypothyroidism

Authors:
Saeed Nazifi, M. Saeb, M. Sepehrimanesh, S. Pourgonabadi

18-04-2024 | Original Article

Protective effects of Allium cepa-fortified feed on testicular function alterations by potassium bromate-induced oxidative damage: an in vivo and in silico approach

Human infertility can arise from various factors including oxidative stress and endocrine disruptors. This study evaluated the protective effects of Allium cepa-fortified feed on testicular function alterations caused by oxidative damage by KBrO3.

Authors:
Charles Obiora Nwonuma, Teslim Alabi Lawal, Marvelous Amarachi Acho, Omokolade O. Alejolowo, Tobiloba C. Elebiyo, Hephzibah Onyeje Obekpa, Oluwafemi Adeleke Ojo, Nnaemeka Tobechukwu Asogwa, Emmanuel Olorunleke Oludipe

18-04-2024 | Intoxication | Review Article

Sudden death syndrome in domestic ruminants: a review

This review provides a comprehensive exploration of factors contributing to sudden death (SD) in ruminants, focusing on cattle, sheep, and goats. The definition of unexpected death varies based on the farming system. In intensive systems, constant …

Authors:
Mokhtar Benchohra, Houari Hemida, Abdelkader Ali-Nehari, Mounir Adnane, Assia Boumezrag, Mira Chikhaoui

05-04-2024 | Acute Lymphoblastic Leukemia | Case Report

T-cell acute lymphoblastic leukemia with atypical intracytoplasmic inclusions in the blasts

In this study, we investigate the utility of flow cytometry as a diagnostic tool for identifying T-cell acute lymphoblastic leukemia (T-ALL). Traditional hematopathological examination has limitations, prompting the need for more accurate …

Authors:
Ashish Ranjan Singh, Prabhat Kumar, Prince Kumar, Bipin Kumar

04-04-2024 | Alzheimer's Disease | Original Article

Antioxidant and anticholinesterase activity of rutin in aluminum chloride-exposed Drosophila melanogaster

Aluminum (Al) toxicity has been associated with multiple neurodegenerative disorders, including Alzheimer’s disease (AD). Since current medications for AD and Al-related toxicity are reported to have significant side effects, the search for …

Authors:
Mary Ekene Iyiegbu, Adaze Bijou Enogieru

08-03-2024 | Biomarkers | Original Article

Influence of dietary supplementation of vitamin A (retinol) on haematology and oxidative stress biomarkers pregnant of West African Dwarf ewes

Vitamin A plays a crucial physiological role in pregnant ewes; it has been documented to be a limited mineral during seasons when pastures are scarce and/or lignified. This study investigated the influence of dietary supplementation of vitamin A …

Authors:
Azeez Olanrewaju Yusuf, Inioluwa Adegbenga Adediran, Oladapo Ayokunle Fasae, Oludotun Olusegun Adelusi, Ayobami John Owolabi

07-03-2024 | Hematology | Original Article

Reticular abscess in buffaloes and cattle: clinical-biochemical, diagnostic imaging findings, treatment and long-term follow-up

The hematological alterations of bovine reticular abscess are reported in literature, but the detailed biochemical alterations and long-term outcome of bovine reticular abscess have not been reported so far and are not available in the standard …

Authors:
Syed Ashaq Hussain, S. K. Uppal, S. K. Mahajan, N. K. Sood, C. S. Randhawa, H. Athar

28-02-2024 | Original Article

Occupational exposure to the dust of chemical fertilizers (NPK 15.15.15): effect on biochemical parameters and oxidative stress status among workers in Annaba

The hazardous elements contained in chemical fertilizers may not only potentially cause adverse health effects to the environment but also to professional health. The current study has been conducted to evaluate the probable effects of chemical …

Authors:
Sara Menadi, Fatima Sara Boubidi, Rim Bouchelaghem, Mahfoud Messarah, Amel Boumendjel

12-02-2024 | Abdominal Surgery | Original Article

Evaluation of the effect of Dracocephalum kotschyi hydroalcoholic extract in preventing intra-abdominal adhesions after abdominal surgery in rats based on inflammatory factors (TNF-α and IL-1β)

Intra-abdominal adhesion is a common complication after abdominal surgery and causes many complications. Inflammatory reactions and oxidative stress are effective in creating adhesions. Several methods have been invented to prevent intra-abdominal …

Authors:
Mahsa Rezvan, Firoozeh Saghaei

07-02-2024 | Original Article

The therapeutic potential of saharian monovarietal virgin olive oil (olea europea l.) on hematological, histological, and antioxidant status in titanium dioxide nanoparticles-induced oxidative stress in rats

Olive oil, particularly monovarietal virgin olive oil (MVOO), has garnered significant attention due to its potential health benefits attributed to a rich composition of bioactive compounds. This study aimed to assess the composition of bioactive …

Authors:
Khaoula Boughediri, Meryem Ouazouaz, Ramzi Triki, Cherifa Henchiri

06-02-2024 | Original Article

Gene expression of hemostasis biomarkers following HIIT and RIPC

To prevent and manage cardiovascular risk factors, two effective strategies are remote ischemic preconditioning and regular exercise training. The objective of this study was to examine how these strategies might affect gene expression of …

Authors:
Shahidi Fereshte, Kashef Majid, Ahmadizad Sajad, Khaje Bahrami Saeed