Biliary atresia (BA) is a rare progressive hepatic disease in children with unclear etiology [ 1 , 2 ]. It is caused by progressive inflammation and fibrosis, which interrupts bile flow and eventually causes severe hepatic injury [ 3 ]. The …
The CblC type of combined methylmalonic acidemia (MMA) and homocysteinemia (CblC disease) caused by mutations in the MMACHC gene is the most common defect in the intracellular cobalamin metabolism pathway, which is also the most common type of MMA …
Infantile epileptic spasms syndrome (IESS), also known as infantile spasms, is a serious disease for infants with a low incidence rate (0.25–0.42/1000 live births) [ 1 ]. It frequently evolves to other epilepsy types or syndromes, especially …
Congenital diaphragmatic hernia (CDH) is a structural birth defect characterized by incomplete formation of the diaphragm, which allows abdominal organs to herniate into the thoracic cavity and impair pulmonary and vascular development. The …
Authors:
Zhi-Yu Chen, Jing Tao, Wen-Li Xu, Yu-Yang Gao, Wen-Yan Li, Zhen Liu, Jia-Yuan Zhou, Li Dai
Bisphenol A (BPA) is a widely used chemical compound found in various products, such as plastic bottles, medical devices, and food packaging coatings [ 1 , 2 ]. BPA can be detected in human biological samples such as blood, urine, placenta, and …
Hypothalamus hamartomas (HHs) are rare, congenital, tumor-like, and nonprogressive malformations composed of heterotopic neurons and glia surrounding the hypothalamus [ 1 ]. The incidence of HH is estimated to be within the range of one per 50,000 …
Recombinant human growth hormone (rhGH) therapy has been widely used in patients with short stature since its initial approval in 1985 [ 1 – 3 ]. However, for short-stature children in late puberty, the rhGH response is often not as good as that of …
Authors:
Xi Bai, Zhi-Bo Zhou, Xiao-Yuan Guo, Yi-Ling He, Yue-Lun Zhang, Feng-Dan Wang, Feng Feng, Hong-Bo Yang, Shi Chen, Feng-Ying Gong, Hui-Juan Zhu, Hui Pan
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in either TSC1 or TSC2 [ 1 ]. This genetic disorder can cause benign, noninvasive lesions in many organs, including the kidney, brain, heart, skin and so on [ 1 …
Authors:
Shuo Dun, Yang-Yang Wang, Lin Wan, Qiu-Hong Wang, Qian Lu, Xiao-Yan Yang, Qi Zhang, Hui-Min Chen, Lu-Peng Qiu, Li-Ping Zou
Childhood and adolescent cancers are major public health concerns [ 1 ]. Hepatoblastoma (HB) is the most common hepatic malignancy in infants and children and accounts for about 50%–60% of primary malignant liver tumors. Over the past 30 years …
Congenital heart defects (CHDs) are the leading causes of neonatal and under-5 deaths and encompass a variety of malformations and anomalies of the heart and great vessels that develop in utero [ 1 ]. Despite a decrease in the global mortality of …
Barbara Vodicska, Júlia Déri, Dóra Tihanyi, Edit Várkondi, Enikő Kispéter, Róbert Dóczi, Dóra Lakatos, Anna Dirner, Mátyás Vidermann, Péter Filotás, Réka Szalkai-Dénes, István Szegedi, Katalin Bartyik, Krisztina Míta Gábor, Réka Simon, Péter Hauser, György Péter, Csongor Kiss, Miklós Garami, István Peták
Childhood or adolescent-onset neurological disorders are prevalent in the pediatric clinic, ranking second only to respiratory disorders, and they are the primary cause of morbidity and mortality among chronic pediatric diseases [ 1 , 2 ]. The …
Authors:
Jing Peng, Wei-Wei Zou, Xiao-Lei Wang, Zhi-Guo Zhang, Ran Huo, Li Yang
In the original publication, the author has missed to include the reference 20 “Fu Y, Tang Z, Ye Z, Mo S, Tian X, Ni K, et al. Human adenovirus type 7 infection causes a more severe disease than type 3. BMC Infect Dis. 2019;19:36” in the reference …
