Skip to main content

Internal and Emergency Medicine OnlineFirst articles

Open Access 15-05-2024 | EM - ORIGINAL

Treat and release: an observational study of non-conveyed high-acuity dispatches in a Danish emergency medical system

Non-conveyance refers to the practice of treating a patient on-site without transporting them to a medical facility. It may decrease unnecessary hospital transfers and improve patient satisfaction. Nonetheless, ensuring patient safety remains …

Authors:
Signe Amalie Wolthers, Tor Jerker Mikaelsson, Mathias Geldermann Holgersen, Stig Nikolaj Fasmer Blomberg, Lars Bredevang Andersen, Søren Mikkelsen, Helle Collatz Christensen

15-05-2024 | CE - LETTER TO THE EDITOR

Carlo Tortoni (1640–1700) and the Early Use of Microscope in Medical Experimentation

Authors:
Michele Augusto Riva, Vincenzo Buontempo

Open Access 14-05-2024 | EM - REVIEW

Food contamination and cardiovascular disease: a narrative review

Cardiovascular disease is a significant cause of morbidity and mortality among non-communicable diseases worldwide. Evidence shows that a healthy dietary pattern positively influences many risk factors of cardiometabolic health, stroke, and heart …

Authors:
Gerardo Mancuso, Francesco Violi, Cristina Nocella

Open Access 14-05-2024 | Stroke | IM - REVIEW

Factor XI Inhibitors: perspectives in primary and secondary prevention of ischemic stroke

Stroke is one of the most common causes of mortality and disability worldwide. Antithrombotic therapy represents the mainstay in primary and secondary prevention, both in cardioembolic and non-cardioembolic stroke. Particularly, direct oral …

Authors:
Domenico Prisco, Maria Canfora, Matteo Mazzetti, Irene Mattioli, Alessandra Bettiol

14-05-2024 | AL Amyloidosis | IM - ORIGINAL

Advancing precision medicine in immunoglobulin light-chain amyloidosis: a novel prognostic model incorporating multi-organ indicators

To develop a more accurate prognostic model that incorporates indicators of multi-organ involvement for immunoglobulin light-chain (AL) Amyloidosis patients. Biopsy-proven AL amyloidosis patients between January 1, 2012, and February 28, 2023 …

Authors:
Yan Xing, Xiayin Li, Jin Zhao, Hao Wu, Lijuan Zhao, Wanting Zheng, Shiren Sun

13-05-2024 | Non-Invasive Ventilation | EM - ORIGINAL

HACOR score to predict NIV failure in patients with COVID-related hypoxemic respiratory failure managed in the ordinary ward and in the critical care setting

We evaluated the prevalence of non-invasive ventilation (NIV) failure among patients with COVID-19-related pneumonia, managed in the ordinary ward and in the HDU/ICU and we tested the prognostic role of the HACOR score in those different settings.

Authors:
Francesco Pepe, Ginevra Fabiani, Carolina Cogozzo, Valerio Mazzilli, Maurizio Villanti, Riccardo Pini, Francesca Innocenti

Open Access 09-05-2024 | IM - ORIGINAL

Monocyte distribution width (MDW) and DECAF: two simple tools to determine the prognosis of severe COPD exacerbation

Monocyte distribution width (MDW) has been associated with inflammation and poor prognosis in various acute diseases. Chronic obstructive pulmonary disease (COPD) exacerbations (ECOPD) are associated with mortality. The objective of this study was …

Authors:
Carlos A. Amado, Cristina Ghadban, Adriana Manrique, Joy Selene Osorio, Milagros Ruiz de Infante, Rodrigo Perea, Laura Gónzalez-Ramos, Sergio García-Martín, Lucia Huidobro, Javier Zuazaga, Patricia Druet, Pedro Argos, Claudia Poo, Ma Josefa Muruzábal, Helena España, Guido Andretta

08-05-2024 | Respiratory Syncytial Virus Infection | IM - CASE RECORD

A man with diarrhea

Respiratory syncytial virus (RSV) primarily affects infants and children and can manifest as upper airway dysfunction. Patients at the highest risk of increased morbidity and mortality from RSV include those who are immunosuppressed and the …

Authors:
Anthony Acosta, Clarence Calhoun, Zane Elfessi

08-05-2024 | Ulcerative Colitis | IM - ORIGINAL

Ulcerative colitis and nephrotic syndrome: a two-sample Mendelian randomization study

To investigate the potential causal relationship between ulcerative colitis and nephrotic syndrome. We obtained the whole-genome association study data of ulcerative colitis in the European population from the GWAS database. Relevant single …

Authors:
Jinfeng Zhan, Yujie Rao, Jiahao Liu, Haizhou Miao, Zhongbin Xia

08-05-2024 | Acute Kidney Injury | IM - COMMENTARY

High versus low chloride load in adult hyperglycemic emergencies with acute kidney injury: a great fluid debate

Authors:
Antonietta Gigante, Francesca Di Mario, Michele Melena, Rosario Cianci, Giovanni Talerico

08-05-2024 | Shock | EM - ORIGINAL

Perfusion index: could it be a new tool for early identification of pulmonary embolism severity?

Perfusion index (PI) is a promising indicator for monitoring peripheral perfusion. The present study aimed to compare the efficiency of PI and PESI score in estimating the 30-day mortality and treatment needs of patients diagnosed with pulmonary …

Authors:
Cemre Ipek Esen, Salim Satar, Muge Gulen, Selen Acehan, Sarper Sevdımbas, Cagdas Ince

08-05-2024 | Pneumonia | EM - ORIGINAL

Bidirectional association between pneumonia and intestinal infection: an analysis of the MIMIC-IV database

The purpose is to analyze the prevalence of intestinal infection in patients with pneumonia in intensive care units (ICU) and the impact of intestinal infection on the prognosis of patients with pneumonia, so as to explore the bidirectional …

Authors:
Weiqian Hou, Yi Zhu, Xigui Lai, Yujie Yang

Open Access 03-05-2024 | Vasovagal Syncope | IM - ORIGINAL

Autonomic responses in young females with typical vasovagal syncope

To determine whether young women who have experienced typical vasovagal syncope (tVVS) have altered autonomic response parameters, based on a battery of autonomic tests and maneuvers. Notably, previous studies including small cohorts and a partial …

Authors:
Ben Amir, Sapir Barak Lanciano, Ronen Rubinshtein, Udi Nussinovitch

Open Access 03-05-2024 | COVID-19 | IM - ORIGINAL

Association between serum levels of GDF-15, suPAR, PIVKA-II, sdLDL and clinical outcomes in hospitalized COVID-19 patients

To quantify the circulating levels of novel serum biomarkers including GDF-15, PIVKA-II, sdLDL, suPAR, and of CRP in hospitalized COVID-19 patients compared with healthy subjects, and to evaluate their association(s) with outcomes in COVID-19. We …

Authors:
Alessio Molfino, Emanuela Anastasi, Eleonora Assanto, Ludovica Toccini, Giovanni Imbimbo, Antonietta Gigante, Valentina Viggiani, Antonella Farina, Orietta Picconi, Antonio Angeloni, Maurizio Muscaritoli
Blood bags

02-05-2024 | Anemia | IM - CASE RECORD Free for a limited time

An atypical adverse reaction to iron infusion

A person receiving a blood transfusion for severe anemia developed acute respiratory distress with hypoxia that resolved after treatment with steroids and supplemental oxygen.

Authors:
Fabiana Belviso, Teodoro Marcianò, Matteo Silva

30-04-2024 | Colorectal Cancer | IM - COMMENTARY

Bridging current knowledge gap: better primary colorectal cancer prevention in people living with metabolic dysfunction-associated steatotic liver

Authors:
Agostino Di Ciaula, Piero Portincasa

Open Access 29-04-2024 | Cardiopulmonary Resuscitation | EM - ORIGINAL

Ecology of emergency care in lower-tier healthcare providers in Ghana: an empirical data-driven Bayesian network analytical approach

The healthcare landscape in Ghana is primarily composed of lower-tier providers, which serve as the initial point of contact for most medical emergencies. This study aimed to assess the emergency care preparedness and readiness of primary …

Authors:
Ebenezer Afrifa-Yamoah, Victor Fannam Nunfam, Bernard Agyei Kwanin, Kwasi Frimpong

29-04-2024 | CE - LETTER TO THE EDITOR

Chinese authors are overrepresented in medical articles retracted for fake peer review or paper mill

On 31 December 2024, I uploaded the RWD, which lists retractions, expressions of concern, and corrections for published articles. The RWD website describes how the authors gathered the data for their database [ 1 ]. I removed from the database all …

Author:
Paul Sebo

Open Access 27-04-2024 | Irritable Bowel Syndrome | IM - ORIGINAL

Site and duration of abdominal pain discriminate symptomatic uncomplicated diverticular disease from previous diverticulitis patients

Abdominal pain in patients with diverticular disease (DD) can be challenging in clinical practice. Patients with symptomatic uncomplicated diverticular disease (SUDD) and patients with a previous acute diverticulitis (PD) may share a similar …

Authors:
Marilia Carabotti, Giovanni Marasco, Caterina Sbarigia, Rosario Cuomo, Giovanni Barbara, Fabio Pace, Giovanni Sarnelli, Bruno Annibale, at behalf of REMAD group

Open Access 26-04-2024 | Colorectal Cancer | IM - ORIGINAL

Fasting hyperglycaemia and fatty liver drive colorectal cancer: a retrospective analysis in 1145 patients

Colorectal cancer (CRC) is one of the most common malignancies in the Western world [ 1 ], ranking as the second leading cause of cancer-related death [ 2 ]. Although colonoscopy represents the gold standard for CRC screening and diagnosis, the …

Authors:
Lucilla Crudele, Carlo De Matteis, Fabio Novielli, Stefano Petruzzelli, Ersilia Di Buduo, Giusi Graziano, Marica Cariello, Elena Piccinin, Raffaella Maria Gadaleta, Antonio Moschetta