Issue 5/2021
Content (28 Articles)
Honorary Professor Garry Graham
Richard O. Day, Kenneth M. Williams, Kieran F. Scott
Limitations of drug concentrations used in cell culture studies for understanding clinical responses of NSAIDs
Garry G. Graham, Kieran F. Scott
Bortezomib: a proteasome inhibitor for the treatment of autoimmune diseases
Naeemeh Khalesi, Shahla Korani, Mitra Korani, Thomas P. Johnston, Amirhossein Sahebkar
Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target
Ehsan Nourbakhsh, Ali Mohammadi, Mohammad Salemizadeh Parizi, Atena Mansouri, Farnoosh Ebrahimzadeh
Thioredoxin-interacting protein (TXNIP) as a target for Alzheimer’s disease: flavonoids and phenols
Meng Zhang, Guanhua Hu, Nan Shao, Yunpeng Qin, Qian Chen, Yan Wang, Peng Zhou, Biao Cai
Recent updates on immunological, pharmacological, and alternative approaches to combat COVID-19
Ammara Saleem, Muhammad Furqan Akhtar, Muhammad Haris, Mohamed M. Abdel-Daim
Management of COVID-19-induced cytokine storm by Keap1-Nrf2 system: a review
Ekta Singh, Gurubasavaraja Swamy Purawarga Matada, Nahid Abbas, Prasad Sanjay Dhiwar, Abhishek Ghara, Arka Das
COVID-19 vaccines and decreased transmission of SARS-CoV-2
A. Vitiello, F. Ferrara, V. Troiano, R. La Porta
A pilot safety, tolerability and pharmacokinetic study of an oro-buccal administered cannabidiol-dominant anti-inflammatory formulation in healthy individuals: a randomized placebo-controlled single-blinded study
Luis Vitetta, Belinda Butcher, Jeremy D. Henson, David Rutolo, Sean Hall
Colchicine effectively attenuates inflammatory biomarker high-sensitivity C-reactive protein (hs-CRP) in patients with non-ST-segment elevation myocardial infarction: a randomised, double-blind, placebo-controlled clinical trial
Arash Gholoobi, Vahid Reza Askari, Hossein Naghedinia, Mostafa Ahmadi, Vida Vakili, Vafa Baradaran Rahimi
Beneficial effect of dimethyl fumarate on experimental autoimmune uveitis is dependent of pro-inflammatory markers immunomodulation
Moussa Labsi, Imene Soufli, Houda Belguendouz, Sara Djebbara, Leila Hannachi, Zine-Charaf Amir, Chafia Touil-Boukoffa
Comparative assessment of proliferation and immunomodulatory potential of Hypericum perforatum plant and callus extracts on mesenchymal stem cells derived adipose tissue from multiple sclerosis patients
Negin Afsharzadeh, Fahimeh Lavi Arab, Mojtaba Sankian, Leila Samiei, Nafiseh Sadat Tabasi, Danial Afsharzadeh, Karim Nikkhah, Mahmoud Mahmoudi
Venlafaxine demonstrated anti-arthritic activity possibly through down regulation of TNF-α, IL-6, IL-1β, and COX-2
Mater Hussen Mahnashi, Zeeshan Jabbar, Alamgeer, Hafiz Muhammad Irfan, Mulazim Hussain Asim, Muhammad Akram, Ahmed Saif, Mohammed Abdulrahman Alshahrani, Mohammed Ali Alshehri, Saeed Ahmed Asiri
Methotrexate and theaflavin-3, 3′-digallate synergistically restore the balance between apoptosis and autophagy in synovial fibroblast of RA: an ex vivo approach with cultured human RA FLS
Sanchaita Misra, Aniruddha Bagchi, Avik Sarkar, Sougata Niyogi, Dipanjan Bhattacharjee, Sulagna Chatterjee, Sumantro Mondal, Arghya Chattopadhyay, Ayindrila Saha, Sudipta Chatterjee, Pradyot Sinhamahapatra, Partha Chakrabarti, Mitali Chatterjee, Alakendu Ghosh
Anti-inflammatory and antioxidant properties of Alternanthera brasiliana improve cutaneous wound healing in rats
Rogério Marchete, Sarah Oliveira, Leonardo Bagne, Jennyffer Ione de Souza Silva, Ana Paula Valverde, Andrea Aparecida de Aro, Mariana Moreira Figueira, Marcio Fronza, Thainá Mikaela Bressam, Vivian Fernandes Furletti de Goes, Fernanda Oliveira de Gaspari de Gaspi, Gláucia Maria Tech dos Santos, Thiago Antônio Moretti Andrade
Effects of nitro-butoxyl- and butyl-esters of non-steroidal anti-inflammatory drugs compared with parent compounds on the contractility of digital arterial smooth muscle from the fallow deer (Dama dama)
Brian A. Callingham, M. Akram Khan, Anthony S. Milton, K. D. Rainsford
Anti-inflammatory activity of palmitoylethanolamide ameliorates osteoarthritis induced by monosodium iodoacetate in Sprague–Dawley rats
Jae In Jung, Hyun Sook Lee, Young Eun Jeon, So Mi Kim, Su Hee Hong, Joo Myung Moon, Cho Young Lim, Yoon Hee Kim, Eun Ji Kim
The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund’s adjuvant-induced chronic inflammatory pain
Xiaoyu Zhang, Fangxia Xu, Lijuan Wang, Jinbao Li, Jianhai Zhang, Lina Huang
Evaluation of antioxidant and anti-ulcerogenic effects of Eremurus persicus (Jaub & Spach) Boiss leaf hydroalcoholic extract on ethanol-induced gastric ulcer in rats
Mohammad Beiranvand, Seifollah Bahramikia, Omid Dezfoulian
Fatty ethanolamide of Bertholletia excelsa triglycerides (Brazil nuts): anti-inflammatory action and acute toxicity evaluation in Zebrafish (Danio rerio)
Yesica Fernanda Quitian-Useche, Brenda Lorena Sánchez-Ortiz, Swanny Ferreira Borges, Benilson Ramos, Gisele Custódio de Souza, Mateus Alves Batista, Lorane Izabel da Silva Hage Melim, Irlon Maciel Ferreira, José Carlos Tavares Carvalho, Raphaelle Sousa Borges
Evaluating the mucoprotective effects of glycyrrhizic acid-loaded polymeric nanoparticles in a murine model of 5-fluorouracil-induced intestinal mucositis via suppression of inflammatory mediators and oxidative stress
Mahira Zeeshan, Ayesha Atiq, Qurat Ul Ain, Jawad Ali, Salman Khan, Hussain Ali
Melatonin reduces inflammation in intestinal cells, organoids and intestinal explants
Xi-Zhang, Xiao-qiang Yuan, Xu-ming Zhang
Acteoside isolated from Colebrookea oppositifolia attenuates I/R brain injury in Wistar rats via modulation of HIF-1α, NF-κB, and VEGF pathways
Gollapalle Lakshminarayanashastry Viswanatha, Hanumanthappa Shylaja, Krishnadas Nandakumar, Subbanna Rajesh, CH K. V. L. S. N. Anjana Male
Diabetic neovascularization defects in the retina are improved by genistein supplementation in the ovariectomized rat
Hadi Yousefi, Alireza Komaki, Siamak Shahidi, Parisa Habibi, Reihaneh Sadeghian, Nasser Ahmadiasl, Faeze Daghigh
Kaempferol potentiates the sensitivity of pancreatic cancer cells to erlotinib via inhibition of the PI3K/AKT signaling pathway and epidermal growth factor receptor
Zhengguang Zhang, Yuanyuan Guo, Meijuan Chen, Feiyan Chen, Bing Liu, Cunsi Shen
Anti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells infected with Cryptococcus neoformans
Bruno Sada Salerno, Aline Beatriz Mahler Pereira, Henrique Ismarsi de Souza, Mario Leon Silva-Vergara, Bruce David Levy, Alexandre Paula Rogerio