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Cardiovascular Toxicology
Published in: Cardiovascular Toxicology 4/2024

02-04-2024 | Hypertension

The Association of Iron Intake and Hypertension, Does Iron Intake Decrease Blood Pressure?

Authors: Mahdi Mousavi Mele, Atefeh Tahavorgar, Zahra Salimi, Ali Shaker, Seyed Ali Askarpour, Mohammad Keshavarz Mohammadian, Seyed Reza Mirshafaei, Zahra Saeedirad, Mahdie Torkaman, Zahra Mahmoudi, Shirin Tajadod, Sara Khoshdooz, Saeid Doaei, Akram Kooshki, Maryam Gholamalizadeh

Published in: Cardiovascular Toxicology | Issue 4/2024

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Abstract

Previous studies reported that iron may have an indispensable role in the risk of hypertension (HTN). However, the result of the studies on the relationship between iron and risk of HTN is inconsistent. This study aimed to assess the association between the association of dietary iron intake and HTN in the Iranian population. This case–control study was conducted on 4184 people aged 35 to 70, including 1239 people with HTN and 2945 people with normal blood pressure (BP) in Sabzevar, Iran. Dietary intake was assessed using a food frequency questionnaire (FFQ). The Nutritionist IV software was used in terms of the assessment of dietary intake of iron. An inverse association was found between iron intake and HTN (OR = 0.97, CI 95%: 0.94–0.99, P = 0.04). The association remained significant after adjustment for age, gender, smoking, drinking alcohol, calorie intake, and BMI (OR = 0.94, CI 95%: 0.89–0.98, P = 0.01). As a conclusion, iron intake was inversely associated with HTN. Further longitudinal studies on the effect of iron intake on BP are required to confirm this finding.
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Metadata
Title
The Association of Iron Intake and Hypertension, Does Iron Intake Decrease Blood Pressure?
Authors
Mahdi Mousavi Mele
Atefeh Tahavorgar
Zahra Salimi
Ali Shaker
Seyed Ali Askarpour
Mohammad Keshavarz Mohammadian
Seyed Reza Mirshafaei
Zahra Saeedirad
Mahdie Torkaman
Zahra Mahmoudi
Shirin Tajadod
Sara Khoshdooz
Saeid Doaei
Akram Kooshki
Maryam Gholamalizadeh
Publication date
02-04-2024
Publisher
Springer US
Published in
Cardiovascular Toxicology / Issue 4/2024
Print ISSN: 1530-7905
Electronic ISSN: 1559-0259
DOI
https://doi.org/10.1007/s12012-024-09848-3

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