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Published in: Archives of Virology 10/2019

01-10-2019 | Hepatitis E | Brief Report

Natural infection of captive cynomolgus monkeys (Macaca fascicularis) with hepatitis E virus genotype 4

Authors: Dmitriy I. Dogadov, L. I. Korzaya, K. K. Kyuregyan, A. A. Karlsen, V. S. Kichatova, I. A. Potemkin, A. M. Goncharenko, M. I. Mikhailov, B. A. Lapin

Published in: Archives of Virology | Issue 10/2019

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Abstract

Data on natural HEV infection of infection in monkeys are limited. We report a case of hepatitis E virus genotype 4 infection in captive non-human primates (cynomolgus monkeys) imported from Vietnam. Phylogenetic analysis demonstrated that HEV infection was not the result of spillover from single source of infection, but rather the persistent circulation of HEV-4 among cynomolgus monkeys or multiple infections by related strains from a human or swine reservoir.
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Literature
3.
go back to reference Tsarev SA, Emerson SU, Tsareva TS, Yarbough PO, Lewis M, Govindarajan S, Reyes GR, Shapiro M, Purcell RH (1993) Variation in course of hepatitis E in experimentally infected cynomolgus monkeys. J Infect Dis 167(6):1302–1306CrossRefPubMed Tsarev SA, Emerson SU, Tsareva TS, Yarbough PO, Lewis M, Govindarajan S, Reyes GR, Shapiro M, Purcell RH (1993) Variation in course of hepatitis E in experimentally infected cynomolgus monkeys. J Infect Dis 167(6):1302–1306CrossRefPubMed
10.
go back to reference Drobeniuc J, Meng J, Reuter G, Greene-Montfort T, Khudyakova N, Dimitrova Z, Kamili S, Teo CG (2010) Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performances. Clin Infect Dis 51(3):24–27. https://doi.org/10.1086/654801 CrossRef Drobeniuc J, Meng J, Reuter G, Greene-Montfort T, Khudyakova N, Dimitrova Z, Kamili S, Teo CG (2010) Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performances. Clin Infect Dis 51(3):24–27. https://​doi.​org/​10.​1086/​654801 CrossRef
11.
go back to reference Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, Haynes JS, Thacker BJ, Emerson SU (1997) A novel virus in swine is closely related to the human hepatitis E virus. Proc Natl Acad Sci USA 94:9860–9865CrossRefPubMed Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, Haynes JS, Thacker BJ, Emerson SU (1997) A novel virus in swine is closely related to the human hepatitis E virus. Proc Natl Acad Sci USA 94:9860–9865CrossRefPubMed
12.
16.
go back to reference Mikhailov MI, Malinnikova EYu, Kyuregyan KK, Isaeva OV (2016) A case of importation of genotype 4 hepatitis E virus in Russia. Zh Mikrobiol Epidemiol Immunobiol 3:64–69 (in Russian) Mikhailov MI, Malinnikova EYu, Kyuregyan KK, Isaeva OV (2016) A case of importation of genotype 4 hepatitis E virus in Russia. Zh Mikrobiol Epidemiol Immunobiol 3:64–69 (in Russian)
17.
go back to reference Korzaia LI, Keburia VV, Dogadov DI, Lapin BA, Kyuregyan KK, Mikhailov MI (2016) Markers of hepatitis E among the population of the Greater Sochi and in monkeys of the Adler primate center. Voprosy Virusologii 61(4):176–180 (in Russian) Korzaia LI, Keburia VV, Dogadov DI, Lapin BA, Kyuregyan KK, Mikhailov MI (2016) Markers of hepatitis E among the population of the Greater Sochi and in monkeys of the Adler primate center. Voprosy Virusologii 61(4):176–180 (in Russian)
Metadata
Title
Natural infection of captive cynomolgus monkeys (Macaca fascicularis) with hepatitis E virus genotype 4
Authors
Dmitriy I. Dogadov
L. I. Korzaya
K. K. Kyuregyan
A. A. Karlsen
V. S. Kichatova
I. A. Potemkin
A. M. Goncharenko
M. I. Mikhailov
B. A. Lapin
Publication date
01-10-2019
Publisher
Springer Vienna
Keyword
Hepatitis E
Published in
Archives of Virology / Issue 10/2019
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-019-04337-3

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