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Clinical Journal of Gastroenterology
Published in: Clinical Journal of Gastroenterology 5/2020

01-10-2020 | Hepatitis A | Case Report

Hepatitis A virus infection in an HIV-positive man with previously confirmed immunity against hepatitis A virus

Authors: Yukihiro Yoshimura, Hiroshi Horiuchi, Nobuyuki Miyata, Makiko Kondo, Natsuo Tachikawa

Published in: Clinical Journal of Gastroenterology | Issue 5/2020

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Abstract

A Japanese man with human immunodeficiency virus (HIV) was detected 9 years ago to have a positive titer for hepatitis A virus (HAV) immunoglobulin (Ig) G, without a history of HAV infection or vaccination. His plasma HIV RNA was well-controlled on antiretroviral therapy for more than 6 years. He developed HAV infection with subsequent reduction of the HAV IgG titer. A decreasing HAV IgG in persons living with HIV might indicate the possibility of HAV reinfection and should prompt the consideration for additional vaccination.
Literature
1.
Freidl GS, Sonder GJ, Bovée LP, et al. Hepatitis A outbreak among men who have sex with men (MSM) predominantly linked with the EuroPride, the Netherlands, July 2016 to February 2017. Euro Surveill. 2017;22:30468.CrossRef
2.
Chen NY, Liu ZH, Shie SS, et al. Clinical characteristics of acute hepatitis A outbreak in Taiwan, 2015–2016: observations from a tertiary medical center. BMC Infect Dis. 2017;17:441.CrossRef
3.
4.
Charre C, Ramière C, Roque-Afonso AM, et al. Hepatitis A outbreak in HIV-infected MSM and in PrEP-using MSM despite a high level of immunity, Lyon, France, January to June 2017. Euro Surveill. 2017;22:17–007422017.CrossRef
5.
Lee HJV, Jeong HS, Cho BK, et al. Evaluation of an immunochromatographic assay for the detection of anti-hepatitis A virus IgM. Virol J. 2010;7:164.CrossRef
6.
Lee MJ, Douthwaite S, Kulasegaram R. Acute hepatitis A infection after hepatitis A immunity in a HIV-positive individual. Sex Transm Infect. 2018;94:30–1.CrossRef
7.
Gallego M, Robles M, Palacios R, et al. Impact of acute hepatitis A virus (HAV) infection on HIV viral load in HIV-infected patients and influence of HIV infection on acute HAV infection. J Int Assoc Physicians AIDS Care (Chic). 2011;10:40–2.CrossRef
8.
Solen K, Odile L, Clément T, et al. Long-term immune responses to vaccination in HIV-infected patients: a systematic review and meta-analysis. Clin Infect Dis. 2014;58:1130–9.CrossRef
9.
DeGroote NP, Mattson CL, Tie Y, et al. Hepatitis A virus immunity and vaccination among at-risk persons receiving HIV medical care. Prev Med Rep. 2018;11:139–44.CrossRef
10.
Brennan J, Moore K, Sizemore L, et al. Notes from the field: acute hepatitis A virus infection among previously vaccinated persons with HIV infection—tennessee, 2018. MMWR Morb Mortal Wkly Rep. 2019;68:328–9.CrossRef
11.
Fritzsche C, Bergmann L, Loebermann M, et al. Immune response to hepatitis A vaccine in patients with HIV. Vaccine. 2019;37:2278–83.CrossRef
12.
13.
14.
Valota M, Thienemann F, Misselwitz B. False-positive serologies for acute hepatitis A and autoimmune hepatitis in a patient with acute Epstein-Barr virus infection. BMJ Case Rep. 2019;12:pii: e228356.CrossRef
15.
De Milito A, Nilsson A, Titanji K, et al. Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection. Blood. 2004;103:2180–6.CrossRef
16.
Gray JR, Steinbrecher UP. False positive anti-hepatitis A virus IgM result in a patient with autoimmune hepatitis. Can J Gastroenterol. 1989;3:115–8.CrossRef
17.
Alatoom A, Ansari MQ, Cuthbert J. Multiple factors contribute to positive results for hepatitis A virus immunoglobulin M antibody. Arch Pathol Lab Med. 2013;137:90–5.CrossRef
18.
19.
Park GC, Hwang S, Yu YD, et al. Intractable recurrent hepatitis A virus infection requiring repeated liver transplantation: a case report. Transplant Proc. 2010;42:4658–60.CrossRef
20.
Eisenbach C, Longerich T, Fickenscher H, et al. Recurrence of clinically significant hepatitis A following liver transplantation for fulminant hepatitis A. J Clin Virol. 2006;35:109–12.CrossRef
21.
Inoue K, Yoshiba M, Yotsuyanagi H, et al. Chronic hepatitis A with persistent viral replication. J Med Virol. 1996;50:322–4.CrossRef
Metadata
Title
Hepatitis A virus infection in an HIV-positive man with previously confirmed immunity against hepatitis A virus
Authors
Yukihiro Yoshimura
Hiroshi Horiuchi
Nobuyuki Miyata
Makiko Kondo
Natsuo Tachikawa
Publication date
01-10-2020
Publisher
Springer Singapore
Published in
Clinical Journal of Gastroenterology / Issue 5/2020
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-020-01102-x

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