Hematology

Cardiac and thrombotic problems are severe outcomes of Kawasaki disease. The standard therapy is intravenous immunoglobulin plus aspirin but the ideal aspirin dose is still controversial.

A young woman with systemic lupus erythematosus presented with pain in her right thigh and restriction of hip movement, and was diagnosed with obturator neuropathy due to lupus-related lymphadenopathy.

A patient with suspected advanced renal cell carcinoma developed thrombotic thrombocytopenic purpura after receiving a single dose of pembrolizumab, underscoring the need for clinician vigilance.

Eosinophilic ascites is a rare but clinically significant manifestation of eosinophilic gastroenteritis, often misdiagnosed as malignancy, tuberculosis, or cirrhosis. Accurate and timely diagnosis and treatment with corticosteroids are key.

People receiving Bruton tyrosine kinase inhibitors for the treatment of B-cell malignancies could be at increased risk for developing pericardial effusion.

Varicose veins and venous thromboembolism can occur in the context of chronic inflammation in inflammatory rheumatic diseases. Find out more about the key risk factors and prevention and rehabilitation strategies.

The CAR T-cell therapy lisocabtagene maraleucel elicits high rates of durable responses in people with relapsed or refractory marginal zone lymphoma, a population with a high unmet need.

Systemic inflammatory disorders are increasingly recognized to exist along a continuum between autoimmunity and autoinflammation. Where does Still disease fall on this spectrum?

This case of subacute inferolateral myocardial infarction secondary to coronary thrombosis occurring after adjuvant doxorubicin–cyclophosphamide therapy in a patient with breast cancer underscores the need for vigilance for uncommon, yet life-threatening, complications.

A case of eosinophilic cholangitis presenting as a localized biliary stricture in a 65-year-old man. As perihilar cholangiocarcinoma could not be ruled out, the patient opted for surgical intervention.

What are the clinical and pathological features of immune thrombocytopenia secondary to systemic lupus erythematosus and Sjögren syndrome? And how can current and emerging therapeutic strategies improve outcomes?

Updated guideline from the German Society for Hematology and Medical Oncology on the prevention, diagnosis, and management of community-acquired respiratory virus infections in people with cancer.

Long-term monitoring for portal hypertension is important – even after resolution of acute sinusoidal obstruction syndrome and achievement of leukemia remission – to optimize outcomes in inotuzumab ozogamicin-treated patients.

Glucocorticoids are cornerstone agents in oncology due to their potent anti-inflammatory, immunosuppressive, and antitumor properties. But it is crucial to strike a balance between therapeutic benefit and harm.

Among people with cancer, the presence of fatigue before starting treatment is associated with an increased risk for severe, life-threatening, or fatal adverse events.

Common infections can trigger macrophage activation syndrome. This case of a 10-year-old girl developing MAS during the convalescence period after varicella highlights the complexities of MAS diagnosis.

Taking hydroxyurea for sickle cell disease shortly before or during pregnancy may not be associated with worse maternal or neonatal outcomes.

A case illustrating a rare but important association between Behçet disease and Hodgkin lymphoma, possibly mediated by immune dysregulation and chronic immunosuppression.

Uveitic macular edema, acute retinal necrosis, and vitreoretinal lymphoma are highly refractory and often result in vision- or life-threatening outcomes. What are the latest advances in imaging, molecular diagnostics, and treatment?

Deaths due to hemophagocytic lymphohistiocytosis in Europe have almost doubled in a decade, highlighting major gaps in awareness, diagnosis, and reporting.