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Published in: Endocrine 3/2019

01-12-2019 | Hashimoto Thyroiditis | Original Article

Is there a correlation between thyroiditis and thyroid cancer?

Authors: Paolo Del Rio, Chiara Montana Montana, Federico Cozzani, Matteo Rossini, Tommaso Loderer, Elisabetta Dall’Aglio, Simona Cataldo, Michela Marina, Ceresini Graziano

Published in: Endocrine | Issue 3/2019

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Abstract

Background

In the past few decades, the incidence of thyroid cancer has increased significantly all over the world. In the same period, there also seems to have been an increase in the incidence of Hashimoto’s Thyroiditis—the most common inflammatory autoimmune thyroid disease. Several studies have linked thyroiditis to thyroid cancer.

Methods

In our study, we examined 2304 cases of thyroid surgery collected over a 12-year period starting from 2004. In 2090 cases (90.7%) out of our sample, it has been possible to compare the presence, or lack thereof, of thyroiditis by means of a histological diagnosis post-surgery; 214 (9.3%) cases were excluded from our study due to insufficient data. We then divided the different histological classifications into two groups. Group A included all the benign histological classifications and Group B included all the malignant histological classifications. In each group, we then assessed the presence, or lack thereof, of thyroiditis in order to evaluate if thyroiditis can be linked to a higher incidence of thyroid cancer.

Results

Data analysis showed a higher incidence of thyroiditis in Group B, 36.4% (malignant pathology report), than in Group A, 32.4% (benign pathology report), but no statistically significant difference emerged between those two groups (P > 0.05).

Conclusions

Our conclusion was that a correlation between thyroiditis and a higher incidence of thyroid cancer is still undefined.
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Metadata
Title
Is there a correlation between thyroiditis and thyroid cancer?
Authors
Paolo Del Rio
Chiara Montana Montana
Federico Cozzani
Matteo Rossini
Tommaso Loderer
Elisabetta Dall’Aglio
Simona Cataldo
Michela Marina
Ceresini Graziano
Publication date
01-12-2019
Publisher
Springer US
Published in
Endocrine / Issue 3/2019
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-019-01935-8

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