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Thyroiditis 

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  1. Open Access 30-04-2024 | Hashimoto Thyroiditis | Online First

    The Underestimated Impact of Hashimoto Thyroiditis on Thyroid Papillary Carcinoma

    It is stated that Hashimoto’s Thyroiditis (HT) is a risk factor for the development of Papillary Thyroid Cancer (PTC). However, the effect of HT on the coexistence of HT and PTC is still controversial. In this study, our aim is to investigate the …

  2. Open Access 01-12-2024 | Autoimmune Hepatitis | OriginalPaper

    Prevalence of autoimmune thyroiditis among children with autoimmune hepatitis

    Autoimmune hepatitis (AIH) is an organ-specific autoimmune disease of unknown etiology that manifests as a chronic inflammatory disease of the liver, typically characterized by periportal inflammation, elevated autoantibodies, and …

  3. Open Access 01-12-2024 | Thyroiditis | OriginalPaper

    Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia

    Autoimmune thyroiditis (AT) is the most common cause of primary hypothyroidism (PHT) in children and adolescents. Atrophic autoimmune thyroiditis (AAT) is a particular form of AT whose incidence is rare in children [ 1 ]. Unlike the classic …

  4. 20-12-2023 | Hypothyroidism | OriginalPaper

    Transition from Hashimoto thyroiditis to Graves’s Disease: an unpredictable change?

    Hashimoto thyroiditis (HT) is a chronic autoimmune disorder due to an immunologic attack with destructive characteristics and very common evolution towards hypothyroidism [ 1 , 2 ]. This is in contrast to the stimulatory immunopathological process …

  5. Open Access 18-04-2024 | Hashimoto Thyroiditis | Online First

    One sip of water with LT-4 supplementation—a key to euthyroidism in Hashimoto’s thyroiditis

    Hashimoto’s thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is the most common autoimmune disease [ 1 ]. The pathophysiology of autoimmune thyroid syndromes, including Graves’ and Basedow’s disease, is believed to result from a …

  6. Open Access 20-04-2024 | Hashimoto Thyroiditis | Online First

    CD20 + T lymphocytes in isolated Hashimoto’s thyroiditis and type 3 autoimmune polyendocrine syndrome: a pilot study

    The non-glycosylated protein CD20 is an immune phenotypic marker associated with B lymphocyte population. 1 However, it has been described a subset of T lymphocytes expressing this surface antigen, as well. 2 Indeed, up to 5% of circulating T …

  7. 27-11-2023 | Hashimoto Thyroiditis | OriginalPaper

    Experimental rat models for Hashimoto’s thyroiditis

    Chronic autoimmune thyroiditis (AIT) or chronic lymphocytic thyroiditis, also known as Hashimoto’s thyroiditis (HT), is an autoimmune thyroid disease characterized by the destruction of thyroid follicles, and manifesting clinically as …

  8. 01-12-2024 | Thyroiditis | OriginalPaper

    Chronic Lymphocytic Thyroiditis with Oncocytic Metaplasia Influences PD-L1 Expression in Papillary Thyroid Carcinoma

    Thyroid cancer (TC) stands as the most common endocrine malignancy, constituting nearly 1% of all human malignancies [ 1 ]. The global incidence of TC has shown a notable increase [ 2 ]. Papillary thyroid carcinoma (PTC) alone comprises around 90% …

  9. 08-03-2024 | Thyroiditis | Online First

    Thyroiditis and COVID-19: focus on pediatric age. A narrative review

    In the pediatric age, the prevalence of thyroid dysfunction is approximately 1–2% [ 1 , 2 ]. The term thyroiditis refers to a wide range of diseases of the thyroid gland that are characterized by some degree of inflammation. It includes thyroid …

  10. Open Access 01-12-2024 | Hashimoto Thyroiditis | ReviewPaper

    Intestinal microbiota regulates the gut-thyroid axis: the new dawn of improving Hashimoto thyroiditis

    Intestinal microbiota plays an indispensable role in the host's innate immune system, which may be related to the occurrence of many autoimmune diseases. Hashimoto thyroiditis (HT) is one of the most common autoimmune diseases, and there is plenty …

  11. 26-12-2023 | Subacute Granulomatous Thyroiditis | ReviewPaper

    The prevalence of positive thyroid autoantibodies in patients with subacute thyroiditis: a systematic review and meta-analysis

    Subacute thyroiditis (SAT), or De Quervain thyroiditis, is a transient inflammatory disorder of the thyroid gland caused by a viral infection or a post-viral inflammatory response. It accounts for up to 5% of all thyroid abnormalities and mostly …

  12. Open Access 01-12-2024 | Langerhans Cell Histiocytosis | OriginalPaper

    Langerhans cell histiocytosis of the thyroid mimicking thyroiditis in a boy: a case report and literature review

    Langerhans cell histiocytosis (LCH) is the monoclonal proliferation of Langerhans cells presenting with CD1a + /CD207 (Langerin) + markers in lesions [ 1 ]. The annual incidence of this disease is 8.9 per million children, under 15 years of age [ 2 …]. LCH can affect many organs, including the bones, skin, lungs, lymph nodes, hypothalamus-pituitary axis, liver, and spleen. The incidence of thyroid involvement is relatively low at 14% in children and 10.10% in adults according to a single-center analysis [

  13. 12-01-2024 | Hashimoto Thyroiditis | Online First

    A systematic review of dysregulated microRNAs in Hashimoto’s thyroiditis

    Autoimmune thyroid diseases (AITDs) are common thyroid disorders resulting from autoimmune thyroid attacks. AITDs are T cell-mediated disorders characterized by lymphocytic infiltration of the thyroid parenchyma. T helper 1 (Th1) lymphocytes are …

  14. 24-02-2024 | Hashimoto Thyroiditis | Online First

    Unraveling the connection between Hashimoto’s Thyroiditis and non-alcoholic fatty liver disease: exploring the role of CD4+central memory T cells through integrated genetic approaches

    Hashimoto’s Thyroiditis (HT), also termed chronic lymphocytic thyroiditis, is one of the most common autoimmune diseases in the world [ 1 , 2 ]. Individuals with HT are also more likely to develop differentiated thyroid cancer and tumors outside of …

  15. 21-01-2024 | Hashimoto Thyroiditis | Online First

    Are sonographic characteristics of Hashimoto’s thyroiditis related with immunologic parameters? A cross-sectional study

    Hashimoto’s thyroiditis (HT) is the most common type of chronic thyroiditis characterized by high serum thyroid antibodies and the presence of goiter. It is the most common cause of goiter and hypothyroidism in populations without iodine …

  16. Open Access 01-12-2024 | Hashimoto Thyroiditis | OriginalPaper

    Effect of Hashimoto’s thyroiditis on the dual-energy CT quantitative parameters and performance in diagnosing metastatic cervical lymph nodes in patients with papillary thyroid cancer

    Papillary thyroid cancer (PTC) accounts for up to 90% of the malignant tumors in the thyroid [ 1 ]. Cervical lymph node (LN) metastasis is highly associated with a poor prognosis of PTC [ 2 ]. Therefore, accurate preoperative identification of …

  17. Open Access 14-10-2023 | Thyrotoxicosis | Case Study

    Thyrotoxicosis as a rare presentation in acute suppurative thyroiditis: a case report

    A rare case of acute suppurative thyroiditis associated with thyrotoxicosis. The patient received antibiotic therapy and underwent drainage of the left thyroid abscess, but ultimately total thyroidectomy was required.  

  18. 03-02-2024 | Thyroiditis | Online First

    A novel homozygous SLC12A3 mutation causing Gitelman syndrome with co-existent autoimmune thyroiditis: a case report and review of the literature

    Gitelman syndrome is a rare, autosomal recessively inherited tubulopathy manifesting with hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. Common symptoms include fatigue, myalgia, reduced performance capacity, tetany …

  19. 29-01-2024 | Thyroiditis | Online First

    Notch signaling regulates Th17 cells differentiation through PI3K/AKT/mTORC1 pathway and involves in the thyroid injury of autoimmune thyroiditis

    Autoimmune thyroiditis (AIT) is a common organ-specific autoimmune disorder characterized by the production of autoantibodies against thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb) and infiltration of inflammatory cells in …

  20. Open Access 01-12-2023 | Thyroiditis | OriginalPaper

    COVISHIELD vaccine-induced thyroiditis: a case report

    The novel coronavirus disease 2019 (COVID-19), which is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in pandemic worldwide. It created a devastating effect on the demographics of the world, causing …

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