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European Journal of Nuclear Medicine and Molecular Imaging

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01-07-2020 | Frontotemporal Dementia | Editorial

Hide-and-seek for radiotracers and neurodegenerative pathology

Author: Karl Herholz

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 8/2020

Excerpt

Hide-and-seek for radiotracers and neurodegenerative pathology …

Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006–14.CrossRef

Grossman M. Primary progressive aphasia: clinicopathological correlations. Nat Rev Neurol. 2010;6(2):88–97.CrossRef

Mann DMA, Snowden JS. Frontotemporal lobar degeneration: pathogenesis, pathology and pathways to phenotype. Brain Pathol. 2017;27(6):723–36.CrossRef

Cho H, Kim HJ, Choi JY, Ryu YH, Lee MS, Na DL, et al. 18F-flortaucipir uptake patterns in clinical subtypes of primary progressive aphasia. Neurobiol Aging. 2019;75:187–97.CrossRef

Pontecorvo MJ, Devous MD Sr, Navitsky M, Lu M, Salloway S, Schaerf FW, et al. Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition. Brain. 2017;140(3):748–63.PubMedPubMedCentral

Harada R, Ishiki A, Kai H, Sato N, Furukawa K, Furumoto S, et al. Correlations of 18F-THK5351 PET with postmortem burden of tau and astrogliosis in Alzheimer disease. J Nucl Med. 2018;59(4):671–4.CrossRef

Carter SF, Herholz K, Rosa-Neto P, Pellerin L, Nordberg A, Zimmer ER. Astrocyte biomarkers in Alzheimer's disease. Trends Mol Med. 2019;25(2):77–95.CrossRef

Baker SL, Harrison TM, Maass A, Joie RL, Jagust WJ. Effect of off-target binding on 18F-flortaucipir variability in healthy controls across the life span. J Nucl Med. 2019;60(10):1444–51.CrossRef

Sweeney MD, Sagare AP, Zlokovic BV. Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders. Nat Rev Neurol. 2018;14(3):133–50.CrossRef

10.

Hahn A, Schain M, Erlandsson M, Sjölin P, James GM, Strandberg OT, et al. Modeling strategies for quantification of in vivo 18F-AV-1451 binding in patients with tau pathology. J Nucl Med. 2017;58(4):623–31.CrossRef

11.

Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain. 2019;142(6):1503–27.CrossRef

Title: Hide-and-seek for radiotracers and neurodegenerative pathology
Author: Karl Herholz
Publication date: 01-07-2020
Publisher: Springer Berlin Heidelberg
Keywords: Frontotemporal Dementia
Frontotemporal Dementia
Alzheimer's Disease
Dementia
Alzheimer's Disease
Dementia
Aphasia
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 8/2020
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-019-04661-5

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