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Heart Failure Reviews
Published in: Heart Failure Reviews 3/2015

01-05-2015

Exosome and its roles in cardiovascular diseases

Authors: Wang Zhao, Xi-Long Zheng, Shui-Ping Zhao

Published in: Heart Failure Reviews | Issue 3/2015

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Abstract

Exosomes are nanosized vesicles secreted by cells, which are capable of carrying signaling molecules in the forms of protein, mRNA and miRNA to serve as the platforms for complex intercellular communications. During the past few years, increasing efforts have been devoted to exosome research, and tremendous progress has been made in terms of identifying the molecular composition, elucidating the mechanisms and regulations of biogenesis and characterizing the functions in a variety of physiological and pathological settings including cardiovascular diseases, a leading cause of morbidity and mortality in modern society. This review provides an update on exosome research and summarizes the roles of exosomes in cardiovascular diseases.
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Metadata
Title
Exosome and its roles in cardiovascular diseases
Authors
Wang Zhao
Xi-Long Zheng
Shui-Ping Zhao
Publication date
01-05-2015
Publisher
Springer US
Published in
Heart Failure Reviews / Issue 3/2015
Print ISSN: 1382-4147
Electronic ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-014-9469-0

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