Issue 5/2019
Content (14 Articles)
Fluctuations in Pharmacokinetics Profiles of Monoclonal Antibodies
Tomasz Grabowski, Joannes A. A. Reijers, Artur Burmańczuk, Anna Chełmońska-Soyta
Opioids: A Review of Pharmacokinetics and Pharmacodynamics in Neonates, Infants, and Children
James C. Thigpen, Brian L. Odle, Sam Harirforoosh
Inhibitory Mechanisms of Myricetin on Human and Rat Liver Cytochrome P450 Enzymes
Dan Lou, Su-su Bao, Ying-hui Li, Qian-meng Lin, Su-fen Yang, Jia-yang He
Pharmacokinetics of the Novel Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone (BAY 94-8862) in Individuals with Mild or Moderate Hepatic Impairment
Roland Heinig, Marc Lambelet, Johannes Nagelschmitz, Abir Alatrach, Atef Halabi
Comparative Evaluation of Median Versus Youden Index Dichotomization Methods: Exposure–Response Analysis of Mycophenolic Acid and Acyl-Glucuronide Metabolite
Malek Okour, Pamala A. Jacobson, Ajay Israni, Richard C. Brundage
Clinical and Pharmacokinetic Outcomes of Peak–Trough-Based Versus Trough-Based Vancomycin Therapeutic Drug Monitoring Approaches: A Pragmatic Randomized Controlled Trial
Fatima Khalifa Al-Sulaiti, Ahmed Mohamed Nader, Mohamed Omar Saad, Adila Shaukat, Rakesh Parakadavathu, Ahmed Elzubair, Daoud Al-Badriyeh, Hazem Elewa, Ahmed Awaisu
In Vitro Study of the Enzymatic and Nonenzymatic Conjugation of Treosulfan with Glutathione
Michał Romański, Franciszek K. Główka
Population Pharmacokinetics of Voriconazole in Chinese Patients with Hematopoietic Stem Cell Transplantation
Chaoyang Chen, Ting Yang, Xinran Li, Lingyun Ma, Yaou Liu, Ying Zhou, Hanyun Ren, Yimin Cui
In Vitro Metabolism by Aldehyde Oxidase Leads to Poor Pharmacokinetic Profile in Rats for c-Met Inhibitor MET401
Jiang Wei Zhang, Hai Bing Deng, Chun Ye Zhang, Jing Quan Dai, Qian Li, Qian Gang Zheng, Hui Xin Wan, Hong Ping Yu, Feng He, Yao Chang Xu, Sylvia Zhao, Ji Yue Jeff Zhang
Pharmacokinetics and Safety of a Diclofenac Sodium 75 mg/1 mL Solution (Akis®/Dicloin®) Administered as a Single Intravenous Bolus Injection in Healthy Men and Women
Chiara Leuratti, Luca Loprete, Matteo Rossini, Valeria Frangione, Stefano Rovati, Milko Radicioni
Minimal Physiologically Based Pharmacokinetic Model of Intravenously and Orally Administered Delta-9-Tetrahydrocannabinol in Healthy Volunteers
William R. Wolowich, Robert Greif, Maren Kleine-Brueggeney, Werner Bernhard, Lorenz Theiler
Inhibitory Effect of Vonoprazan on the Metabolism of [14C]Prasugrel in Human Liver Microsomes
Mitsuhiro Nishihara
Comment on: Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Healthy Chinese Subjects
Nuggehally R. Srinivas
Author’s Reply to: “Comment on: Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Chinese Healthy Subjects”
Ran Xie, Yang Zhang, Nan Zhao, Shuang Zhou, Xin Wang, Wei Han, Yan Yu, Xia Zhao, Yimin Cui