Endocrinology

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

Selenium and zinc deficiency led to thyroid dysfunction in a patient who received total parenteral nutrition without trace element supplementation for one and a half months after intestinal resection.

Thyrotoxicosis in a patient with a THRβ mutation was kept under control for 5 years by treatment with 3,5,3-triiodothyroacetic acid. Loss of efficacy occurred after autoimmune hyperthyroidism developed.

Late orbital radiotherapy combined with intravenous methylprednisolone successfully treated a patient with recurrent and long-lasting unilateral reactivating Graves’ orbitopathy.

Rapidly progressive insulin-dependent diabetes in the absence of islet autoantibodies developed 2 years after starting treatment with the immune checkpoint inhibitor nivolumab.

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

HC-HB is a rare movement disorder that can occur in patients with poorly controlled diabetes and hyperglycemia without ketoacidosis. The mainstay of treatment is prompt correction of hyperglycemia.

A pancreatic neuroendocrine microtumor with a high proliferation rate but metabolic, genetic, and epigenetic features correlated with a less aggressive disease course highlights the need to better understand PanNET tumorigenesis.

This case report considers two cases of type 1 diabetes diagnosed after multiple COVID-19 vaccinations. HLA haplotypes associated with susceptibility to type 1 diabetes were present in both cases.

Although rare, primary thyroid lymphoma should be considered in cases of rapidly growing goiters. Timely needle biopsy can avoid unnecessary surgery.

Diabetic radiculoplexus neuropathy, or Bruns–Garland syndrome, is a rare form of microvascular complication that more commonly affects the lumbosacral plexus and, very rarely, the cervical plexus.

Signs of scurvy are non-specific and wide ranging, so vitamin C deficiency is often misdiagnosed. This is the first case of DVT caused by large pelvic subperiosteal hematomas in an autistic boy with severe dietary restriction.

HNF1A mutations are responsible for maturity-onset diabetes of the young (MODY). Coexistence of POF and MODY 3 in an adolescent girl raised the idea that these mutations might also have a role in POF.

Awareness that lymphocytic hypophysitis can present without hypopituitarism is key as early intervention can prevent progression of visual disturbances and the need for surgery.

Ectopic thyroid is very rarely found as a solitary tumor in the submandibular region, but it should be considered in the differential diagnosis when papillary structures are seen on histopathology.

A rare case of thyroid gland blastomycosis in an immunocompromised man with a history of heart transplant who presented with leukocytosis and pneumonia. Blastomycosis was also evident in the heart, lungs, liver, pancreas, and skin.

A patient with small-cell lung cancer developed type 1 diabetes many weeks after receiving serplulimab, highlighting the need for continued monitoring of blood glucose levels and early signs and symptoms of diabetes.

A diagnosis of glycogen storage disease type IX is easy to overlook, but it should be considered in children presenting with unexplained hepatomegaly and elevated transaminase levels. Genetic analysis is vital for accurate diagnosis.

A case of treatment-resistant hyperparathyroidism with severe complications in a long-term kidney dialysis patient, who presented with an atypically located adenoma that required comprehensive surgical intervention.

Pediatric pulmonary hypertension related to vitamin C deficiency can manifest in multiple ways, from mild symptoms to life-threatening episodes characterized by pulmonary hypertensive crises. This educational study looks at two pediatric cases.