Published in:
11-11-2022 | Diseases of the neuromuscular synapses and muscles | Correspondence
Awake malignant hyperthermia: report of a case to help prevent crises in operating rooms
Authors:
Natalia Puerto, MD, Kazuyoshi Aoyama, MD, PhD, Tara Der, MD, Igor Luginbuehl, MD, Cengiz Karsli, MD, Reinhard Zeller, MD, Christian Zaarour, MD
Published in:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie
|
Issue 1/2023
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Excerpt
Rare malignant hyperthermia (MH) crises termed “nonanesthetic,” “awake MH,” or “MH-like” reactions may present outside the operating room or without anesthetic triggers,
1‐3 incited by viral infections, stress, and dehydration.
1‐3 Dantrolene is used to prevent and treat these cases. Awake MH presents as a hypermetabolic state (e.g., hyperthermia, sustained contracture, rhabdomyolysis, hyperkalemia); unrecognized and untreated, it can progress to arrhythmias and cardiac arrest. Diagnosing, preventing, and treating awake MH remain challenging. We report on the perioperative management of a pediatric patient with a history of awake MH episodes. Written informed consent was obtained from the patient’s legal guardian for the publication of this report. …
