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3729 search results for:

Malignant Hyperthermia 

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  1. Open Access 01-12-2024 | Malignant Hyperthermia | OriginalPaper

    Remimazolam-based total intravenous anesthesia in a patient with a confirmed diagnosis of malignant hyperthermia: a case report

    Malignant hyperthermia (MH) is a rare, life-threatening, and pharmacogenetic disorder precipitated by the administration of halogenated volatile anesthetics, such as sevoflurane or desflurane and the depolarizing muscle relaxant succinylcholine [ 1 …–

  2. Open Access 01-12-2023 | Malignant Hyperthermia | ReviewPaper

    The 100 most cited articles in malignant hyperthermia

    Bibliometric analysis is a widely used method to identify and evaluate the trends and characteristics of the scientific publications in a specific research field. A large volume of literature has been published in the field of malignant

  3. Open Access 01-12-2023 | Metabolic Acidosis | OriginalPaper

    Pediatric fulminant malignant hyperthermia with severe electroencephalographic abnormality and brain damage: a case report

    Malignant hyperthermia (MH), which requires immediate intervention, is an extremely dangerous condition that can occur with exposure to volatile inhalant anesthetics and depolarizing muscle relaxants. In MH, the rate of calcium (Ca) release from …

  4. Open Access 01-12-2023 | Malignant Hyperthermia | OriginalPaper

    A WeChat applet-based national remote emergency system for malignant hyperthermia in China: a usability study

  5. Awake malignant hyperthermia: report of a case to help prevent crises in operating rooms

    Rare malignant hyperthermia (MH) crises termed “nonanesthetic,” “awake MH,” or “MH-like” reactions may present outside the operating room or without anesthetic triggers, 1 – 3 incited by viral infections, stress, and dehydration. 1 – 3 Dantrolene …

  6. 01-03-2022 | Malignant Hyperthermia

    Comment on “Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture”

    The results from Sagui et al. [ 2 ] are remarkable and have indeed never been confirmed by other researchers. In their study, muscle biopsies were taken from the biceps brachii, an uncommon biopsy site for samples used for the in vitro contracture …

  7. 01-12-2021 | Malignant Hyperthermia

    Malignant hyperthermia when dantrolene is not readily available

    Malignant hyperthermia (MH) is a rare but life-threatening pharmacogenetic muscle disorder characterized by abnormal hypermetabolic reactions and commonly triggered in susceptible individuals by volatile anesthetics or succinylcholine, or both.

  8. 01-03-2022 | Malignant Hyperthermia | OriginalPaper

    Spinal cord injury-related thermoregulatory impairment masks a fatal malignant hyperthermia crisis: a case report

    Consent for this report has been obtained from the parents of the patient. This case report adheres to CARE guidelines for reporting of case reports. CARE. Case report guidelines. Available from URL: https://www.care-statement.org (accessed October …

  9. 01-03-2022 | Malignant Hyperthermia | Letter

    Response to Comment on “Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture”

    It appears that van den Bersselaar et al. question the data and methods reported by Sagui et al. [ 3 ]. It is important to clarify that we are not associated with Sagui et al. [ 3 ] whatsoever. Therefore, we are unable to take responsibility for or …

  10. Open Access 01-12-2021 | Malignant Hyperthermia | Letter

    General anesthesia with remimazolam in a patient with clinically suspected malignant hyperthermia

  11. Open Access 01-12-2021 | Malignant Hyperthermia | OriginalPaper

    Preparation of Dräger Atlan A350 and General Electric Healthcare Carestation 650 anesthesia workstations for malignant hyperthermia susceptible patients

    Malignant hyperthermia (MH) is an inherited pharmaco-genetic disorder in which affected individuals are at risk to develop life-threatening metabolic crises when in contact to volatile anesthetics and/or succinylcholine. Whenever patients with a …

  12. 01-04-2021 | Diaphragmatic Hernia | OriginalPaper

    Malignant hyperthermia in a 16-day-old infant with congenital diaphragmatic hernia: a case report

    Malignant hyperthermia (MH) is a severe hypermetabolic disorder associated with dysregulation of calcium homeostasis and is triggered by inhalational anesthetics (isoflurane, sevoflurane, desflurane) and a depolarizing muscle relaxant …

  13. Open Access 01-12-2021 | Breast Cancer | OriginalPaper

    Postoperative malignant hyperthermia confirmed by calcium-induced calcium release rate after breast cancer surgery, in which prompt recognition and immediate dantrolene administration were life-saving: a case report

    Malignant hyperthermia (MH) is a very rare disease, in which symptoms are induced by a pharmacogenomic reaction, caused by genetic mutations in the ryanodine receptor 1 (RYR1) gene, which encodes a calcium channel protein. The prevalence of MH is …

  14. Open Access 01-12-2020 | Malignant Hyperthermia | OriginalPaper

    Impact of statin intake on malignant hyperthermia: an in vitro and in vivo swine study

    Statins are widely prescribed drugs to treat hypercholesterolemia due to a safe profile and significant efficacy at reducing cardiovascular-related morbidities in coronary artery disease patients, as well as in healthy individuals [ 1 , 2 ]. A …

  15. Open Access 01-12-2020 | Malignant Hyperthermia | OriginalPaper

    Prevalence of malignant hyperthermia diagnosis in obstetric patients in the United States, 2003 to 2014

    Malignant hyperthermia (MH) is a pharmacogenetic disorder of the skeletal muscle triggered by halogenated inhalational agents or the depolarizing muscle relaxant succinylcholine [ 1 , 2 ]. Exposure to triggering agents can lead to a rapid and …

  16. 01-09-2020 | Malignant Hyperthermia

    Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture

    Exertional heat stroke (EHS) and malignant hyperthermia (MH) are life-threatening conditions, triggered by different environmental stimuli that share several clinical symptoms and pathophysiological features. EHS manifests during physical activity …

  17. 01-05-2019 | Malignant Hyperthermia | OriginalPaper

    Fatal awake malignant hyperthermia episodes in a family with malignant hyperthermia susceptibility: a case series

    Informed consent for this report was obtained from the relevant family members.

  18. Preclinical model systems of ryanodine receptor 1-related myopathies and malignant hyperthermia: a comprehensive scoping review of works published 1990–2019

    Ryanodine receptor 1-related myopathies ( RYR1 -RM) are a diverse spectrum of rare monogenic neuromuscular disorders that manifest from variations in the RYR1 gene [ 1 , 2 ]. In total, > 700 RYR1 variations have been identified; many of which are …

  19. 01-06-2021 | Malignant Hyperthermia | EditorialNotes

    Unravelling the unseen metabolic changes in patients with malignant hyperthermia

  20. Open Access 01-12-2019 | Dystonia | OriginalPaper

    GTP-Cyclohydrolase I deficiency presenting as malignant hyperphenylalaninemia, recurrent hyperthermia and progressive neurological dysfunction in a South Asian child – a case report

    Tetrahydrobiopterin (BH 4 ) deficiencies comprises a heterogeneous group of disorders caused by mutations at one of the genes encoding enzymes involved in the biosynthesis(GTP cyclohydrolase I or 6-pyruvoyltetrahydropterinsynthase) or regeneration …

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