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International Journal of Colorectal Disease
Published in: International Journal of Colorectal Disease 4/2020

01-04-2020 | Coma | Original Article

Is abdominal vascular calcification score valuable in predicting the occurrence of colorectal anastomotic leakage? A meta-analysis

Authors: Lingling Tong, Di Xie, Xiangping Song, Xin Wu, Shiwu Wen, Aizhong Liu

Published in: International Journal of Colorectal Disease | Issue 4/2020

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Abstract

Objective

Anastomotic leakage (AL) is a catastrophic surgical complication affecting the prognosis of patients after colorectal surgery. We aimed to determine the value of the arterial calcification (AC) score in predicting AL.

Methods

Medline and Embase were searched through November 2019. The odds ratio (OR) and 95% confidence interval (CI) were used to estimate the association between AC and AL after colorectal surgery. The fixed-effects model or random-effects model was adopted for data pooling. Subgroup analyses were conducted to assess the effect of different aortoiliac trajectories.

Results

Four studies involving 496 patients were included. The calcium volume and calcium score measurements of different trajectories revealed a significant difference with regard to the left and right common iliac arteries, the superior mesenteric artery, and the left common iliac artery. Calcification of the internal iliac artery significantly increased the risk of AL compared with no AL (OR = 1.005; 95% CI 1.002–1.009; P = 0.005), as did calcification of the left internal iliac artery (OR = 1.009; 95% CI 1.002–1.016; P = 0.011), but not of the common iliac artery (OR = 1.001; 95% CI 1.000–1.001; P = 0.317) or common and internal iliac artery (OR = 1.000; 95% CI 1.000–1.000; P = 1.000).

Conclusions

AC is associated with increased risk of AL following colorectal surgery.

Trial registration

CRD42019141236
Appendix
Available only for authorised users
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Metadata
Title
Is abdominal vascular calcification score valuable in predicting the occurrence of colorectal anastomotic leakage? A meta-analysis
Authors
Lingling Tong
Di Xie
Xiangping Song
Xin Wu
Shiwu Wen
Aizhong Liu
Publication date
01-04-2020
Publisher
Springer Berlin Heidelberg
Keyword
Coma
Published in
International Journal of Colorectal Disease / Issue 4/2020
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-020-03513-1

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