Issue 12/2023
Content (11 Articles)
Acknowledgement to Referees
Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs)
Sebastian Sten, Tim Cardilin, Madeleine Antonsson, Peter Gennemark
The Pharmacokinetics of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone
Roland Heinig, Thomas Eissing
High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints
Anouk M. E. Jansen, Rob ter Heine, Paul E. Verweij, Roger J. M. Brüggemann
Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies
Anouk M. E. Jansen, Beatrijs Mertens, Isabel Spriet, Paul E. Verweij, Jeroen Schouten, Joost Wauters, Yves Debaveye, Rob ter Heine, Roger J. M. Brüggemann
Pharmacokinetics and Tolerability of Zibotentan in Patients with Concurrent Moderate Renal and Moderate Hepatic Impairment
Anne-Kristina Mercier, Mikael Sunnåker, Sebastian Ueckert, Tadeusz Pawlik, Emilia Henricson, Oleksandr Molodetskyi, Gordon C. Law, Victoria E. R. Parker, Jan Oscarsson
Population Pharmacokinetics of Digoxin in Nonagenarian Patients: Optimization of the Dosing Regimen
Angel Luis Salcedo-Mingoarranz, Susanna Edith Medellín-Garibay, Emilia Barcia-Hernández, Benito García-Díaz
Safety, Pharmacokinetics, and Pharmacodynamics of SHR7280, a Non-peptide GnRH Antagonist in Premenopausal Women with Endometriosis: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
Yuan Li, Ying Zheng, Bing Xu, Linrui Cai, Sheng Feng, Yiming Liu, Zhenyi Zhu, Qin Yu, Hongyan Guo
Prognostic Value of Nivolumab Clearance in Non-Small Cell Lung Cancer Patients for Survival Early in Treatment
Leila S. Otten, Berber Piet, Demy van den Haak, Robert D. Schouten, Milou Schuurbiers, Sushil K. Badrising, Emmy Boerrigter, Sjaak A. Burgers, Rob ter Heine, Michel M. van den Heuvel
A Phase I, Open-Label, Fixed Sequence Study to Investigate the Effect of Cytochrome P450 2D6 Inhibition on the Pharmacokinetics of Ulotaront in Healthy Subjects
Hironobu Tsukada, Yu-Luan Chen, Guangqing Xiao, Lisa Lennek, Snezana M. Milanovic, MaryAlice Worden, Daniel G. Polhamus, Yu-Yuan Chiu, Seth C. Hopkins, Gerald R. Galluppi
Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development
Jessica Wojciechowski, Vivek S Purohit, Yeamin Huh, Christopher Banfield, Timothy Nicholas