Issue 11/2019
Content (9 Articles)
Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting Them
Sheila Annie Peters, Hugues Dolgos
Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches
Gaëlle Magliocco, Aurélien Thomas, Jules Desmeules, Youssef Daali
Immune Checkpoint Inhibitors in Melanoma: A Review of Pharmacokinetics and Exposure–Response Relationships
Cyril Leven, Maël Padelli, Jean-Luc Carré, Eric Bellissant, Laurent Misery
What Antibiotic Exposures Are Required to Suppress the Emergence of Resistance for Gram-Negative Bacteria? A Systematic Review
Chandra Datta Sumi, Aaron J. Heffernan, Jeffrey Lipman, Jason A. Roberts, Fekade B. Sime
Optimal Sampling Strategies for Therapeutic Drug Monitoring of First-Line Tuberculosis Drugs in Patients with Tuberculosis
Antonia Morita I. Saktiawati, Marcel Harkema, Althaf Setyawan, Yanri W. Subronto, Sumardi, Ymkje Stienstra, Rob E. Aarnoutse, Cecile Magis-Escurra, Jos G. W. Kosterink, Tjip S. van der Werf, Jan-Willem C. Alffenaar, Marieke G. G. Sturkenboom
Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis
Christine Xu, Yaming Su, Anne Paccaly, Vanaja Kanamaluru
Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, for the Treatment of Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Invasive Procedures
Takayuki Katsube, Ryosuke Shimizu, Takahiro Fukuhara, Takeshi Kano, Toshihiro Wajima
Population Pharmacokinetics of Mycophenolic Acid Co-Administered with Tacrolimus in Corticosteroid-Free Adult Kidney Transplant Patients
Yan Rong, Patrick Mayo, Mary H. H. Ensom, Tony K. L. Kiang
The Effect of Food Intake on the Pharmacokinetics of Oral Basal Insulin: A Randomised Crossover Trial in Healthy Male Subjects
Inge B. Halberg, Karsten Lyby, Karsten Wassermann, Tim Heise, Leona Plum-Mörschel, Eric Zijlstra