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International Ophthalmology

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01-01-2020 | Review

Changes in axial length after orthokeratology lens treatment for myopia: a meta-analysis

Authors: Meng Guan, Weijia Zhao, Yu Geng, Yang Zhang, Jia Ma, Zonghan Chen, Mingqian Peng, Yan Li

Published in: International Ophthalmology | Issue 1/2020

Abstract

Purpose

Orthokeratology (OK) lens is a popular optical method to control myopia progression. This study aimed to assess the effect of OK lens on axial length change compared with glasses.

Methods

PubMed, Web of Science, and Embase were searched to retrieve the related articles. Then, the articles were selected according to predefined criteria. Standardized mean difference (SMD) and 95% confidence interval (CI) were selected as effect size for combining and analyzing the change in axial length.

Results

A total of 13 articles were included in the present study. Different models were selected according to the heterogeneity of each analysis. The axial length change in OKs group was significantly smaller than control group; SMD (95% CI) of change in axial length was − 0.857 (− 1.146, − 0.568), p < 0.001 at the end of 1 year and − 0.701 (− 1.675, 0.272), p < 0.001 at the end of 2 years or longer time.

Conclusions

OK lens treatment appears more effective in slowing axial elongation than glasses during the early treatment of myopia in children.

Rudnicka AR, Kapetanakis VV, Wathern AK, Logan NS, Gilmartin B, Whincup PH, Cook DG, Owen CG (2016) Global variations and time trends in the prevalence of childhood myopia, a systematic review and quantitative meta-analysis: implications for aetiology and early prevention. Br J Ophthalmol 100(7):882–890. https://doi.org/10.1136/bjophthalmol-2015-307724 CrossRefPubMedPubMedCentral

Morgan IG, Ohno-Matsui K, Saw SM (2012) Myopia. Lancet 379(9827):1739–1748. https://doi.org/10.1016/S0140-6736(12)60272-4 CrossRefPubMed

Resnikoff S, Pascolini D, Mariotti SP, Pokharel GP (2008) Global magnitude of visual impairment caused by uncorrected refractive errors in 2004. Bull World Health Organ 86(1):63–70CrossRef

Morgan I, Rose K (2005) How genetic is school myopia? Prog Retin Eye Res 24(1):1–38. https://doi.org/10.1016/j.preteyeres.2004.06.004 CrossRefPubMed

Pan CW, Ramamurthy D, Saw SM (2012) Worldwide prevalence and risk factors for myopia. Ophthalmic Physiol Opt 32(1):3–16. https://doi.org/10.1111/j.1475-1313.2011.00884.x CrossRefPubMed

Swarbrick HA, Alharbi A, Watt K, Lum E, Kang P (2015) Myopia control during orthokeratology lens wear in children using a novel study design. Ophthalmology 122(3):620–630. https://doi.org/10.1016/j.ophtha.2014.09.028 CrossRefPubMed

Vitale S, Sperduto RD, Ferris FL (2009) Increased prevalence of myopia in the United States between 1971–1972 and 1999–2004. Arch Ophthalmol 127(12):1632–1639. https://doi.org/10.1001/archophthalmol.2009.303 CrossRefPubMed

Saw SM, Goh PP, Cheng A, Shankar A, Tan DT, Ellwein LB (2006) Ethnicity-specific prevalences of refractive errors vary in Asian children in neighbouring Malaysia and Singapore. Br J Ophthalmol 90(10):1230–1235. https://doi.org/10.1136/bjo.2006.093450 CrossRefPubMedPubMedCentral

Congdon N, Wang Y, Song Y, Choi K, Zhang M, Zhou Z, Xie Z, Li L, Liu X, Sharma A, Wu B, Lam DS (2008) Visual disability, visual function, and myopia among rural chinese secondary school children: the Xichang Pediatric Refractive Error Study (X-PRES)–report 1. Invest Ophthalmol Vis Sci 49(7):2888–2894. https://doi.org/10.1167/iovs.07-1160 CrossRefPubMed

10.

Saw SM, Gazzard G, Shih-Yen EC, Chua WH (2005) Myopia and associated pathological complications. Ophthalmic Physiol Opt 25(5):381–391. https://doi.org/10.1111/j.1475-1313.2005.00298.x CrossRefPubMed

11.

Rein DB, Zhang P, Wirth KE, Lee PP, Hoerger TJ, McCall N, Klein R, Tielsch JM, Vijan S, Saaddine J (2006) The economic burden of major adult visual disorders in the United States. Arch Ophthalmol 124(12):1754–1760. https://doi.org/10.1001/archopht.124.12.1754 CrossRefPubMed

12.

Verhoeven VJ, Wong KT, Buitendijk GH, Hofman A, Vingerling JR, Klaver CC (2015) Visual consequences of refractive errors in the general population. Ophthalmology 122(1):101–109. https://doi.org/10.1016/j.ophtha.2014.07.030 CrossRefPubMed

13.

Zhu MJ, Feng HY, He XG, Zou HD, Zhu JF (2014) The control effect of orthokeratology on axial length elongation in Chinese children with myopia. BMC Ophthalmol 14:141. https://doi.org/10.1186/1471-2415-14-141 CrossRefPubMedPubMedCentral

14.

Smith EL III (2013) Optical treatment strategies to slow myopia progression: effects of the visual extent of the optical treatment zone. Exp Eye Res 114:77–88. https://doi.org/10.1016/j.exer.2012.11.019 CrossRefPubMedPubMedCentral

15.

Lee JJ, Fang PC, Yang IH, Chen CH, Lin PW, Lin SA, Kuo HK, Wu PC (2006) Prevention of myopia progression with 0.05% atropine solution. J Ocul Pharmacol Ther 22(1):41–46. https://doi.org/10.1089/jop.2006.22.41 CrossRefPubMed

16.

Walline JJ, Jones LA, Sinnott LT (2009) Corneal reshaping and myopia progression. Br J Ophthalmol 93(9):1181–1185. https://doi.org/10.1136/bjo.2008.151365 CrossRefPubMed

17.

Hiraoka T, Kakita T, Okamoto F, Takahashi H, Oshika T (2012) Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study. Invest Ophthalmol Vis Sci 53(7):3913–3919. https://doi.org/10.1167/iovs.11-8453 CrossRefPubMed

18.

Sun Y, Xu F, Zhang T, Liu M, Wang D, Chen Y, Liu Q (2015) Orthokeratology to control myopia progression: a meta-analysis. PLoS ONE 10(4):e0124535. https://doi.org/10.1371/journal.pone.0124535 CrossRefPubMedPubMedCentral

19.

Maddern GJ, Thavaneswaran P, Coventry BJ (2014) Evaluation of surgical safety and efficacy. Springer, LondonCrossRef

20.

Margulis AV, Pladevall M, Riera-Guardia N, Varas-Lorenzo C, Hazell L, Berkman ND, Viswanathan M, Perez-Gutthann S (2014) Quality assessment of observational studies in a drug-safety systematic review, comparison of two tools: the Newcastle–Ottawa Scale and the RTI item bank. Clin Epidemiol 6(8):359–368CrossRef

21.

Cho P, Cheung SW (2017) Discontinuation of orthokeratology on eyeball elongation (DOEE). Cont Lens Anterior Eye 40(2):82–87. https://doi.org/10.1016/j.clae.2016.12.002 CrossRefPubMed

22.

Chen C, Cheung SW, Cho P (2013) Myopia control using toric orthokeratology (TO-SEE study). Invest Ophthalmol Vis Sci 54(10):6510–6517. https://doi.org/10.1167/iovs.13-12527 CrossRefPubMed

23.

Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutierrez-Ortega R, Sugimoto K (2017) Long-term efficacy of orthokeratology contact lens wear in controlling the progression of childhood myopia. Curr Eye Res 42(5):713–720. https://doi.org/10.1080/02713683.2016.1221979 CrossRefPubMed

24.

Charm J, Cho P (2013) High myopia-partial reduction ortho-k: a 2-year randomized study. Optom Vis Sci 90(6):530–539. https://doi.org/10.1097/OPX.0b013e318293657d CrossRefPubMed

25.

He M, Du Y, Liu Q, Ren C, Liu J, Wang Q, Li L, Yu J (2016) Effects of orthokeratology on the progression of low to moderate myopia in Chinese children. BMC Ophthalmol 16:126. https://doi.org/10.1186/s12886-016-0302-5 CrossRefPubMedPubMedCentral

26.

Cho P, Cheung SW (2012) Retardation of myopia in Orthokeratology (ROMIO) study: a 2-year randomized clinical trial. Invest Ophthalmol Vis Sci 53(11):7077–7085. https://doi.org/10.1167/iovs.12-10565 CrossRefPubMed

27.

Cheung SW, Cho P (2016) Long-term effect of orthokeratology on the anterior segment length. Cont Lens Anterior Eye 39(4):262–265. https://doi.org/10.1016/j.clae.2016.02.003 CrossRefPubMed

28.

Kakita T, Hiraoka T, Oshika T (2011) Influence of overnight orthokeratology on axial elongation in childhood myopia. Invest Ophthalmol Vis Sci 52(5):2170–2174. https://doi.org/10.1167/iovs.10-5485 CrossRefPubMed

29.

Paun J (2015) Myopia control with a novel peripheral gradient soft lens and orthokeratology: a 2-year clinical trial. Biomed Res Int 2015(D):507572. https://doi.org/10.1155/2015/507572 CrossRef

30.

MaYA Na (2018) The effect of orthokeratology on axial length elongation in children with myopia: contralateral comparison study. Jpn J Ophthalmol 62(3):327–334. https://doi.org/10.1007/s10384-018-0573-x CrossRef

31.

Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, Wong TY, Naduvilath TJ, Resnikoff S (2016) Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology 123(5):1036–1042. https://doi.org/10.1016/j.ophtha.2016.01.006 CrossRefPubMed

32.

Meng W, Butterworth J, Malecaze F, Calvas P (2011) Axial length of myopia: a review of current research. Ophthalmologica 225(3):127–134. https://doi.org/10.1159/000317072 CrossRefPubMed

33.

Young TL, Metlapally R, Shay AE (2007) Complex trait genetics of refractive error. Arch Ophthalmol 125(1):38–48. https://doi.org/10.1001/archopht.125.1.38 CrossRefPubMed

34.

Smith MJ, Walline JJ (2015) Controlling myopia progression in children and adolescents. Adolesc Health Med Ther 6:133–140. https://doi.org/10.2147/AHMT.S55834 CrossRefPubMedPubMedCentral

35.

Aller TA (2014) Clinical management of progressive myopia. Eye (Lond) 28(2):147–153. https://doi.org/10.1038/eye.2013.259 CrossRef

36.

Cooper J, Schulman E, Jamal N (2012) Current status on the development and treatment of myopia. Optometry 83(5):179–199PubMed

37.

Liu YM, Xie P (2016) The safety of orthokeratology—a systematic review. Eye Contact Lens 42(1):35–42. https://doi.org/10.1097/ICL.0000000000000219 CrossRefPubMed

38.

Caroline PJ (2001) Contemporary orthokeratology. Cont Lens Anterior Eye 24(1):41–46CrossRef

39.

Lum E, Swarbrick HA (2011) Lens Dk/t influences the clinical response in overnight orthokeratology. Optom Vis Sci 88(4):469–475. https://doi.org/10.1097/OPX.0b013e31820bb0db CrossRefPubMed

40.

Cheung SW, Cho P, Fan D (2004) Asymmetrical increase in axial length in the two eyes of a monocular orthokeratology patient. Optom Vis Sci 81(9):653–656CrossRef

41.

Si JK, Tang K, Bi HS, Guo DD, Guo JG, Wang XR (2015) Orthokeratology for myopia control: a meta-analysis. Optom Vis Sci 92(3):252–257. https://doi.org/10.1097/OPX.0000000000000505 CrossRefPubMed

42.

Cho P, Cheung SW, Edwards M (2005) The longitudinal orthokeratology research in children (LORIC) in Hong Kong: a pilot study on refractive changes and myopic control. Curr Eye Res 30(1):71–80CrossRef

43.

Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutierrez-Ortega R (2012) Myopia control with orthokeratology contact lenses in Spain: refractive and biometric changes. Invest Ophthalmol Vis Sci 53(8):5060–5065. https://doi.org/10.1167/iovs.11-8005 CrossRefPubMed

Title: Changes in axial length after orthokeratology lens treatment for myopia: a meta-analysis
Authors: Meng Guan
Weijia Zhao
Yu Geng
Yang Zhang
Jia Ma
Zonghan Chen
Mingqian Peng
Yan Li
Publication date: 01-01-2020
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 1/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-019-01167-9

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Changes in axial length after orthokeratology lens treatment for myopia: a meta-analysis

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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