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International Ophthalmology
Published in: International Ophthalmology 1/2020

Open Access 01-01-2020 | Allergic Rhinitis | Original Paper

Association between allergic conjunctivitis and provisional tic disorder in children

Authors: Lin Chen, Xinke Chen, Ning Ke, Lianhong Pi, Qing Liu

Published in: International Ophthalmology | Issue 1/2020

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Abstract

Background

Allergic diseases are associated with a higher risk of Tourette’s syndrome (TS). Provisional tic disorder (PTD) and eye blinking are often reported as the initial symptoms both in TS and in allergic conjunctivitis (AC).

Objective

To investigate the association between AC and PTD in children of 4–10 years of age in southwest China.

Methods

This case–control study was carried out at the Children’s Hospital of Chongqing Medical University between January 2016 and June 2017. Age- and gender-matched children without PTD were included as the control group. Intraocular pressure was measured by non-contact tonometry, tear film break-up time by slit-lamp examination, and allergens by skin prick test (SPT). Multivariable logistic regression analysis was applied to adjust for the simultaneous effects of AC, dry eye, and allergic history in children with PTD.

Results

The frequency of AC was higher in the PTD group (74.3%, 52/70) than in the control group (17.1%, 12/70) (P < 0.001). The frequencies of positive SPT were found to be higher in the PTD group (80.0%, 56/70) than in the control group (20.0%, 14/70). AC, dry eye, and history of allergic rhinitis were significantly associated with PTD.

Conclusion

The frequencies of AC are high in children with PTD. AC and dry eye may be both associated with PTD in children.
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Metadata
Title
Association between allergic conjunctivitis and provisional tic disorder in children
Authors
Lin Chen
Xinke Chen
Ning Ke
Lianhong Pi
Qing Liu
Publication date
01-01-2020
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 1/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-019-01174-w

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