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Published in: Neurocritical Care 3/2021

01-06-2021 | Central Nervous System Trauma | Practical Pearl

Intravenous Immunoglobulin (IVIG) in Severe Heparin-Induced Thrombocytopenia (HIT) in a Traumatic Brain Injury (TBI) Patient with Cerebral Venous Sinus Thrombosis (CVST)

Authors: Niall A. Buckley, Mustafa K. Baskaya, Marin E. Darsie

Published in: Neurocritical Care | Issue 3/2021

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Excerpt

There is an absence of literature discussing heparin-induced thrombocytopenia (HIT) management in traumatic brain injury (TBI) patients with post-traumatic cerebral venous sinus thrombosis (CVST). …
Literature
1.
go back to reference Nguyen R, Fiest K, McChesney J, et al. The international incidence of traumatic brain injury: a systematic review and meta-analysis. Can J Neurol Sci. 2016;43(6):774–85.CrossRef Nguyen R, Fiest K, McChesney J, et al. The international incidence of traumatic brain injury: a systematic review and meta-analysis. Can J Neurol Sci. 2016;43(6):774–85.CrossRef
2.
go back to reference Dewan M, Rattani A, Gupta S, et al. Estimating the global incidence of traumatic brain injury. J Neurosurg. 2019;130(4):1080–97.CrossRef Dewan M, Rattani A, Gupta S, et al. Estimating the global incidence of traumatic brain injury. J Neurosurg. 2019;130(4):1080–97.CrossRef
3.
go back to reference Delgado Almandoz J, Kelly H, Schaefer P, Lev M, Gonzalez R, Romero J. Prevalence of traumatic dural venous sinus thrombosis in high-risk acute blunt head trauma patients evaluated with multidetector CT venography. Radiology. 2010;255(2):570–7.CrossRef Delgado Almandoz J, Kelly H, Schaefer P, Lev M, Gonzalez R, Romero J. Prevalence of traumatic dural venous sinus thrombosis in high-risk acute blunt head trauma patients evaluated with multidetector CT venography. Radiology. 2010;255(2):570–7.CrossRef
4.
go back to reference Filippidis A, Kapsalaki E, Patramani G, Fountas K. Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment. Neurosurg Focus. 2009;27(5):E3.CrossRef Filippidis A, Kapsalaki E, Patramani G, Fountas K. Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment. Neurosurg Focus. 2009;27(5):E3.CrossRef
5.
go back to reference Saposnik G, Barinagarrementeria F, Brown R, et al. Diagnosis and management of cerebral venous thrombosis. Stroke. 2011;42(4):1158–92.CrossRef Saposnik G, Barinagarrementeria F, Brown R, et al. Diagnosis and management of cerebral venous thrombosis. Stroke. 2011;42(4):1158–92.CrossRef
6.
go back to reference Smythe M, Koerber J, Mattson J. The incidence of recognized heparin-induced thrombocytopenia in a large. Tert Care Teach Hosp Chest. 2007;131(6):1644–9. Smythe M, Koerber J, Mattson J. The incidence of recognized heparin-induced thrombocytopenia in a large. Tert Care Teach Hosp Chest. 2007;131(6):1644–9.
7.
go back to reference Arepally G, Ortel T. Heparin-induced thrombocytopenia. Annu Rev Med. 2010;61(1):77–90.CrossRef Arepally G, Ortel T. Heparin-induced thrombocytopenia. Annu Rev Med. 2010;61(1):77–90.CrossRef
8.
go back to reference Martel N, Lee J, Wells P. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood. 2005;106(8):2710–5.CrossRef Martel N, Lee J, Wells P. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood. 2005;106(8):2710–5.CrossRef
9.
go back to reference Kim J, Gearhart M, Zurick A, Zuccarello M, James L, Luchette F. Preliminary report on the safety of heparin for deep venous thrombosis prophylaxis after severe head injury. J Trauma Inj Infect Crit Care. 2002;53(1):38–433.CrossRef Kim J, Gearhart M, Zurick A, Zuccarello M, James L, Luchette F. Preliminary report on the safety of heparin for deep venous thrombosis prophylaxis after severe head injury. J Trauma Inj Infect Crit Care. 2002;53(1):38–433.CrossRef
10.
go back to reference Ning S, Warkentin T. IV immunoglobulin for autoimmune heparin-induced thrombocytopenia. Chest. 2017;152(3):453–5.CrossRef Ning S, Warkentin T. IV immunoglobulin for autoimmune heparin-induced thrombocytopenia. Chest. 2017;152(3):453–5.CrossRef
11.
go back to reference Park B, Kumar M, Nagalla S, et al. Intravenous immunoglobulin as an adjunct therapy in persisting heparin-induced thrombocytopenia. Transfus Apheres Sci. 2018;57(4):561–5.CrossRef Park B, Kumar M, Nagalla S, et al. Intravenous immunoglobulin as an adjunct therapy in persisting heparin-induced thrombocytopenia. Transfus Apheres Sci. 2018;57(4):561–5.CrossRef
12.
go back to reference Mohanty E, Nazir S, Sheppard J, Forman D, Warkentin T. High-dose intravenous immunoglobulin to treat spontaneous heparin-induced thrombocytopenia syndrome. J Thromb Haemost. 2019;17(5):841–4.CrossRef Mohanty E, Nazir S, Sheppard J, Forman D, Warkentin T. High-dose intravenous immunoglobulin to treat spontaneous heparin-induced thrombocytopenia syndrome. J Thromb Haemost. 2019;17(5):841–4.CrossRef
13.
go back to reference Irani M, Siegal E, Jella A, Aster R, Padmanabhan A. Use of intravenous immunoglobulin G to treat spontaneous heparin-induced thrombocytopenia. Transfusion. 2018;59(3):931–4.CrossRef Irani M, Siegal E, Jella A, Aster R, Padmanabhan A. Use of intravenous immunoglobulin G to treat spontaneous heparin-induced thrombocytopenia. Transfusion. 2018;59(3):931–4.CrossRef
14.
go back to reference Ammann EM, Haskins CB, Fillman KM, et al. Intravenous immune globulin and thromboembolic adverse events: a systematic review and meta-analysis of RCTs. Am J Hematol. 2016;91(6):594–605.CrossRef Ammann EM, Haskins CB, Fillman KM, et al. Intravenous immune globulin and thromboembolic adverse events: a systematic review and meta-analysis of RCTs. Am J Hematol. 2016;91(6):594–605.CrossRef
15.
go back to reference Thomas S, Makris M. The reversal of anticoagulation in clinical practice. Clin Med. 2018;18(4):314–9.CrossRef Thomas S, Makris M. The reversal of anticoagulation in clinical practice. Clin Med. 2018;18(4):314–9.CrossRef
16.
go back to reference Warkentin T, Crowther M. Reversing anticoagulants both old and new. Can J Anaesth. 2002;49:S11–S25.PubMed Warkentin T, Crowther M. Reversing anticoagulants both old and new. Can J Anaesth. 2002;49:S11–S25.PubMed
17.
go back to reference Lee C, Ansell J. Direct thrombin inhibitors. Br J Clin Pharmacol. 2011;72(4):581–92.CrossRef Lee C, Ansell J. Direct thrombin inhibitors. Br J Clin Pharmacol. 2011;72(4):581–92.CrossRef
18.
go back to reference Joppa S, Salciccioli J, Adamski J, et al. A practical review of the emerging direct anticoagulants, laboratory monitoring, and reversal agents. J Clin Med. 2018;7(2):29.CrossRef Joppa S, Salciccioli J, Adamski J, et al. A practical review of the emerging direct anticoagulants, laboratory monitoring, and reversal agents. J Clin Med. 2018;7(2):29.CrossRef
Metadata
Title
Intravenous Immunoglobulin (IVIG) in Severe Heparin-Induced Thrombocytopenia (HIT) in a Traumatic Brain Injury (TBI) Patient with Cerebral Venous Sinus Thrombosis (CVST)
Authors
Niall A. Buckley
Mustafa K. Baskaya
Marin E. Darsie
Publication date
01-06-2021

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